DK1039895T3 - Anvendelse af 3-benzoylphenyleddikesyrer, estere eller amider til behandling af GLC1A-glaukom - Google Patents

Anvendelse af 3-benzoylphenyleddikesyrer, estere eller amider til behandling af GLC1A-glaukom

Info

Publication number
DK1039895T3
DK1039895T3 DK98960732T DK98960732T DK1039895T3 DK 1039895 T3 DK1039895 T3 DK 1039895T3 DK 98960732 T DK98960732 T DK 98960732T DK 98960732 T DK98960732 T DK 98960732T DK 1039895 T3 DK1039895 T3 DK 1039895T3
Authority
DK
Denmark
Prior art keywords
amides
esters
treat
glaucoma
benzoylphenylacetic acids
Prior art date
Application number
DK98960732T
Other languages
English (en)
Inventor
John M Yanni
Mark R Hellberg
Original Assignee
Alcon Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Lab Inc filed Critical Alcon Lab Inc
Application granted granted Critical
Publication of DK1039895T3 publication Critical patent/DK1039895T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
DK98960732T 1997-12-19 1998-12-04 Anvendelse af 3-benzoylphenyleddikesyrer, estere eller amider til behandling af GLC1A-glaukom DK1039895T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/994,903 US6066671A (en) 1997-12-19 1997-12-19 Treatment of GLC1A glaucoma with 3-benzoyl-phenylacetic acids, esters, or amides
PCT/US1998/025744 WO1999032104A1 (en) 1997-12-19 1998-12-04 Use of 3-benzoyl-phenylacetic acids, esters, or amides for treatment of glc1a glaucoma

Publications (1)

Publication Number Publication Date
DK1039895T3 true DK1039895T3 (da) 2002-09-23

Family

ID=25541199

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98960732T DK1039895T3 (da) 1997-12-19 1998-12-04 Anvendelse af 3-benzoylphenyleddikesyrer, estere eller amider til behandling af GLC1A-glaukom

Country Status (13)

Country Link
US (2) US6066671A (da)
EP (1) EP1039895B1 (da)
JP (1) JP2001526218A (da)
AT (1) ATE218336T1 (da)
AU (1) AU746075C (da)
BR (1) BR9813767A (da)
CA (1) CA2313386A1 (da)
DE (1) DE69805846T2 (da)
DK (1) DK1039895T3 (da)
ES (1) ES2178291T3 (da)
HK (1) HK1027748A1 (da)
PT (1) PT1039895E (da)
WO (1) WO1999032104A1 (da)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6475724B1 (en) * 1997-01-28 2002-11-05 The Regents Of The University Of California Nucleic acids, kits, and methods for the diagnosis, prognosis and treatment of glaucoma and related disorders
US7138511B1 (en) 1997-01-28 2006-11-21 The Regents Of The University Of California Nucleic acids, kits and methods for the diagnosis, prognosis and treatment of glaucoma and related disorders
US6646001B2 (en) 1997-12-19 2003-11-11 Alcon Manufacturing, Ltd. Use of non-steroidal anti-inflammatory agents in combination with prostaglandin FP receptor agonists to treat glaucoma and ocular hypertension
US6066671A (en) * 1997-12-19 2000-05-23 Alcon Laboratories, Inc. Treatment of GLC1A glaucoma with 3-benzoyl-phenylacetic acids, esters, or amides
US6416777B1 (en) * 1999-10-21 2002-07-09 Alcon Universal Ltd. Ophthalmic drug delivery device
BR0014929B1 (pt) 1999-10-21 2009-01-13 dispositivo para distribuiÇço de medicamento oftÁlmico.
US7943162B2 (en) 1999-10-21 2011-05-17 Alcon, Inc. Drug delivery device
AR030346A1 (es) * 2000-08-14 2003-08-20 Alcon Inc Metodo de tratamiento de desordenes neurodegenerativos de la retina y cabeza de nervio optico
AR030345A1 (es) * 2000-08-14 2003-08-20 Alcon Inc Metodo de tratamiento de desordenes relacionados con angiogenesis
BR0210287A (pt) 2001-07-23 2005-12-13 Alcon Inc Dispositivo de administração de droga oftalmológica
DE60217679T2 (de) 2001-07-23 2007-10-25 Alcon Inc. Vorrichtung zur freisetzung eines ophthalmischen arzneimittels
US20040132773A1 (en) * 2001-08-13 2004-07-08 Gamache Daniel A Method of treating neurodgenerative disorders of the retina and optic nerve head
US20030119000A1 (en) * 2001-11-05 2003-06-26 Jon Polansky Methods to screen and treat individuals with glaucoma or the propensity to develop glaucoma
CN1649575A (zh) * 2002-05-03 2005-08-03 爱尔康公司 用氨芬酸或奈帕芬胺治疗血管内皮生长因子介导的血管疾病的方法
US6864282B2 (en) 2002-08-05 2005-03-08 Allergan, Inc. 9,11-cycloendoperoxide pro-drugs of prostaglandin analogues for treatment of ocular hypertension and glaucoma
EP1586316B1 (en) * 2003-01-21 2008-04-30 Senju Pharmaceutical Co., Ltd. Aqueous liquid preparation containing 2-amino-3-(4-bromobenzoyl)phenylacetic acid
US20040225014A1 (en) * 2003-02-14 2004-11-11 Sucampo Ag Method for treating ocular hypertension and glaucoma
US20030187072A1 (en) * 2003-02-14 2003-10-02 Kapin Michael A. Method of treating angiogenesis-related disorders
WO2005014046A2 (en) * 2003-08-07 2005-02-17 Allergan, Inc. Compositions for delivery of therapeutics into the eyes and methods for making and using the same
WO2005044276A1 (ja) 2003-11-07 2005-05-19 Senju Pharmaceutical Co., Ltd. プロスタグランジン含有医薬組成物
ATE412400T1 (de) * 2004-11-09 2008-11-15 Novagali Pharma Sa Öl-in-wasser-emulsion mit niedriger konzentration des kationischen mittels und positivem zetapotential
TWI358290B (en) * 2004-12-02 2012-02-21 Alcon Inc Topical nepafenac formulations
EP2026651B1 (en) * 2006-03-08 2013-04-17 Cortria Corporation Combination therapy with non-selective cox inhibitors to prevent cox-related gastric injuries
WO2008080110A1 (en) * 2006-12-21 2008-07-03 Alcon, Inc. Methods for treating macular edema and pathologic ocular angiogenesis using a neuroprotective agent and a receptor tyrosine kinase inhibitor
US20080153818A1 (en) * 2006-12-21 2008-06-26 Bingaman David P Methods for preventing inflammation during surgery
US20090105245A1 (en) * 2006-12-21 2009-04-23 Bingaman David P Methods for treating macular edema and ocular angiogenesis using an anti-inflammatory agent and a receptor tyrosine kinase inhibitor
US20100292289A1 (en) * 2007-11-30 2010-11-18 Ampla Pharmaceuticals Inc. Treatment of metabolic syndrome with novel amides
EP2127638A1 (en) 2008-05-30 2009-12-02 Santen Pharmaceutical Co., Ltd Method and composition for treating ocular hypertension and glaucoma
WO2010056741A2 (en) * 2008-11-12 2010-05-20 Auspex Pharmaceuticals, Inc. Phenylacetic acid inhibitors of cyclooxygenase
US20110293549A1 (en) 2009-02-03 2011-12-01 Athena Cosmetics, Inc. Composition, method and kit for enhancing hair
EP2228058A1 (en) 2009-03-04 2010-09-15 Novagali Pharma S.A. Anionic oil-in-water emulsion containing prostaglandins and uses thereof
EP2389939A1 (en) 2010-05-28 2011-11-30 Novagali Pharma S.A. Use of prostaglandins F2alpha and analogues for the healing of corneal and conjunctival lesions
EP3013790A1 (en) 2013-06-27 2016-05-04 Mylan Laboratories Ltd. Process for the preparation of nepafenac

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA805476B (en) * 1979-09-26 1981-11-25 Robins Co Inc A H 2-amino-3-benzoyl-phenylacetamides and cyclic homologues
US4683242A (en) * 1985-10-28 1987-07-28 A. H. Robins Company, Incorporated Transdermal treatment for pain and inflammation with 2-amino-3-aroylbenzeneacetic acids, salts and esters
US5151444B1 (en) 1987-09-18 1999-07-06 R Tech Ueno Ltd Ocular hypotensive agents
US5565492A (en) 1988-07-18 1996-10-15 Alcon Laboratories, Inc. Prostaglandin combinations in glaucoma therapy
DE1300150T1 (de) 1988-09-06 2003-09-18 Pharmacia Ab Prostaglandin-Derivate zur Behandlung von Glaukom oder Augenüberdruck
US5093329A (en) 1990-03-12 1992-03-03 Allergan, Inc. Intraocular pressure reducing prostaglandin-like 7-oxabicyclo derivatives
US5270049A (en) 1990-11-09 1993-12-14 Allergan, Inc. 2-decarboxyl-2-aminoalkyl-prostaglandins as ocular hypotensives
US5510383A (en) 1993-08-03 1996-04-23 Alcon Laboratories, Inc. Use of cloprostenol, fluprostenol and their salts and esters to treat glaucoma and ocular hypertension
US5721273A (en) 1993-12-15 1998-02-24 Alcon Laboratories, Inc. Use of certain 9-halo-13,14-dihydroprostaglandins to treat glaucoma and ocular hypertension
US5627209A (en) 1993-12-15 1997-05-06 Alcon Laboratories, Inc. Use of certain 9-haloprostaglandins to treat glaucoma and ocular hypertension
US5474985A (en) * 1993-12-22 1995-12-12 The Regents Of The University Of California Preventing and treating elevated intraocular pressure associated with administered or endogenous steroids using non-steroidal cyclooxygenase inhibitors
US5475034A (en) * 1994-06-06 1995-12-12 Alcon Laboratories, Inc. Topically administrable compositions containing 3-benzoylphenylacetic acid derivatives for treatment of ophthalmic inflammatory disorders
US5698733A (en) 1994-09-30 1997-12-16 Alcon Laboratories, Inc. Use of 9-deoxy prostaglandin derivatives to treat glaucoma
US5807892A (en) 1994-09-30 1998-09-15 Alcon Laboratories, Inc. Use of certain prostaglandin analogues to treat glaucoma and ocular hypertension
US5891913A (en) * 1994-10-10 1999-04-06 Novartis Finance Corporation Ophthalmic and aural compositions containing diclofenac potassium
US5606043A (en) * 1994-11-03 1997-02-25 The Regents Of The University Of California Methods for the diagnosis of glaucoma
US5925673A (en) 1994-12-23 1999-07-20 Alcon Laboratories, Inc. Benzofurans and benzopyrans as cytoprotective agents
US5607966A (en) 1994-12-23 1997-03-04 Alcon Laboratories, Inc. Esters and amides of non-steroidal anti-inflammatory carboxylic acids which may be used as anti-oxidants, 5-lipoxygenase inhibitors and non-steroidal anti-inflammatory prodrugs
US5674888A (en) * 1995-06-07 1997-10-07 University Of California Method for the treatment of a trabecular meshwork whose cells are subject to inhibition of cell division
WO1998021180A1 (en) * 1995-06-07 1998-05-22 Alcon Laboratories, Inc. Conformationally rigid aryl- or heteroaryl prostaglandins for use in glaucoma therapy
US5599535A (en) * 1995-06-07 1997-02-04 Regents Of The University Of California Methods for the cyto-protection of the trabecular meshwork
US5750564A (en) 1995-09-12 1998-05-12 Hellberg; Mark Anti-oxidant esters of non-steroidal anti-inflammatory agents
ATE273009T1 (de) 1995-12-22 2004-08-15 Alcon Lab Inc Substituierte tetrahydrofuran-analoge von prostaglandinen als augendrucksenkende mittel
US5814660A (en) 1995-12-22 1998-09-29 Alcon Laboratories, Inc. 9-oxa prostaglandin analogs as ocular hypotensives
US5866602A (en) 1995-12-22 1999-02-02 Alcon Laboratories, Inc. Keto-substituted tetrahydrofuran analogs of prostaglandins as ocular hypotensives
WO1998039293A2 (en) * 1997-03-07 1998-09-11 Alcon Laboratories, Inc. 13-thia prostaglandins for use in glaucoma therapy
US6066671A (en) * 1997-12-19 2000-05-23 Alcon Laboratories, Inc. Treatment of GLC1A glaucoma with 3-benzoyl-phenylacetic acids, esters, or amides
SE9803761D0 (sv) 1998-11-04 1998-11-04 Synphora Ab Method to avoid increased iridial pigmentation during prostaglandin treatment

Also Published As

Publication number Publication date
HK1027748A1 (en) 2001-01-23
ATE218336T1 (de) 2002-06-15
EP1039895A1 (en) 2000-10-04
US6342524B1 (en) 2002-01-29
PT1039895E (pt) 2002-10-31
AU1625999A (en) 1999-07-12
DE69805846T2 (de) 2003-01-16
CA2313386A1 (en) 1999-07-01
US6066671A (en) 2000-05-23
BR9813767A (pt) 2000-10-03
DE69805846D1 (de) 2002-07-11
AU746075C (en) 2002-10-17
WO1999032104A1 (en) 1999-07-01
AU746075B2 (en) 2002-04-11
EP1039895B1 (en) 2002-06-05
JP2001526218A (ja) 2001-12-18
ES2178291T3 (es) 2002-12-16

Similar Documents

Publication Publication Date Title
DK1039895T3 (da) Anvendelse af 3-benzoylphenyleddikesyrer, estere eller amider til behandling af GLC1A-glaukom
DK112190A (da) Prostaglandinderivater til behandling af glaukom eller foroeget okulaert tryk
MX9702349A (es) Usos de derivado de 9-deoxi prostaglandina para tratar glaucoma.
DK1920764T3 (da) Fluprostenolisopropylester til anvendelse i behandling af glaukom og okulær hypertension
ATE356113T1 (de) Probucolbernsteinsäureester zur hemmung der expression von vcam-1
BR9811099A (pt) Inibidores de urocinase
DE69430538D1 (de) 2-azylalkyl-oder arylalenyl-cyclopentanheptan-und heptensäuren, derivate und therapeutische anwendung
DE60016181D1 (de) C-16 ungesätigte fp-selektive prostaglandin analoge
AU687906B2 (en) Use of certain prostaglandin analogues to treat glaucoma and ocular hypertension
NO980296L (no) Forbedrede terapeutiske midler
SE9401087D0 (sv) New prostaglandin derivatives for the treatment of glaucoma or ocular hypertension
YU17999A (sh) Novi derivati pentaeritrita, njihova izrada i primena kao i međuproizvodi za njihovu sintezu
MY115877A (en) Cyclopeptolides