ES2175184T3 - Virus que expresan proteinas toxicas y leneas celulares productoras. - Google Patents
Virus que expresan proteinas toxicas y leneas celulares productoras.Info
- Publication number
- ES2175184T3 ES2175184T3 ES96945414T ES96945414T ES2175184T3 ES 2175184 T3 ES2175184 T3 ES 2175184T3 ES 96945414 T ES96945414 T ES 96945414T ES 96945414 T ES96945414 T ES 96945414T ES 2175184 T3 ES2175184 T3 ES 2175184T3
- Authority
- ES
- Spain
- Prior art keywords
- viruses
- toxic proteins
- producing cellular
- cellular lines
- express toxic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
- C12N2740/13041—Use of virus, viral particle or viral elements as a vector
- C12N2740/13043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
- C12N2760/20222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
- C12N2830/002—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor
- C12N2830/003—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor tet inducible
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/10—Vectors comprising a special translation-regulating system regulates levels of translation
- C12N2840/105—Vectors comprising a special translation-regulating system regulates levels of translation enhancing translation
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
SE DESCRIBEN VECTORES DE EXPRESION QUE PRESENTAN UN PROMOTOR FUERTEMENTE CONTROLABLE, QUE DIRIGE LA EXPRESION DE UNA PROTEINA FUSOGENICA. TAMBIEN SE DESCRIBEN MOLECULAS DE ACIDOS NUCLEICOS QUE CODIFICAN TOXICOS DE PROTEINAS FUSOGENICAS, ESTANDO ALTERADOS UNO O MAS RESTOS CISTEINA DE LA MOLECULA DEL ACIDO NUCLEICO PARA PRODUCIR UN CODON DE TERMINACION OPALO.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US58055495A | 1995-12-29 | 1995-12-29 | |
US58055695A | 1995-12-29 | 1995-12-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2175184T3 true ES2175184T3 (es) | 2002-11-16 |
Family
ID=27078078
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES96945414T Expired - Lifetime ES2175184T3 (es) | 1995-12-29 | 1996-12-20 | Virus que expresan proteinas toxicas y leneas celulares productoras. |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0870050B1 (es) |
JP (1) | JP2000502261A (es) |
AT (1) | ATE219521T1 (es) |
DE (1) | DE69621949T2 (es) |
DK (1) | DK0870050T3 (es) |
ES (1) | ES2175184T3 (es) |
PT (1) | PT870050E (es) |
WO (1) | WO1997024452A2 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2337520B (en) * | 1998-05-22 | 2000-06-14 | Oxford Biomedica Ltd | Delivery system |
CA2340335A1 (en) * | 1998-08-20 | 2000-03-02 | Cell Genesys, Inc. | Use of suppressor trna's to regulate cytotoxicity during the production of recombinant gene products |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4963481A (en) * | 1985-12-18 | 1990-10-16 | Genetics Institute Inc | Promoter system |
US5512421A (en) * | 1991-02-19 | 1996-04-30 | The Regents Of The University Of California | Generation, concentration and efficient transfer of VSV-G pseudotyped retroviral vectors |
-
1996
- 1996-12-20 WO PCT/US1996/020587 patent/WO1997024452A2/en active IP Right Grant
- 1996-12-20 EP EP96945414A patent/EP0870050B1/en not_active Expired - Lifetime
- 1996-12-20 ES ES96945414T patent/ES2175184T3/es not_active Expired - Lifetime
- 1996-12-20 DK DK96945414T patent/DK0870050T3/da active
- 1996-12-20 DE DE69621949T patent/DE69621949T2/de not_active Expired - Fee Related
- 1996-12-20 AT AT96945414T patent/ATE219521T1/de not_active IP Right Cessation
- 1996-12-20 JP JP09523909A patent/JP2000502261A/ja not_active Ceased
- 1996-12-20 PT PT96945414T patent/PT870050E/pt unknown
Also Published As
Publication number | Publication date |
---|---|
PT870050E (pt) | 2002-10-31 |
EP0870050B1 (en) | 2002-06-19 |
JP2000502261A (ja) | 2000-02-29 |
EP0870050A2 (en) | 1998-10-14 |
WO1997024452A3 (en) | 1997-11-06 |
DE69621949T2 (de) | 2002-09-26 |
DE69621949D1 (de) | 2002-08-01 |
ATE219521T1 (de) | 2002-07-15 |
WO1997024452A2 (en) | 1997-07-10 |
DK0870050T3 (da) | 2002-07-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NZ316787A (en) | Methods and compositions for the selective modification of nucleic acids | |
ATE188740T1 (de) | Viruspartikel mit veraendertem wirtspektrum | |
NO964862D0 (no) | Papillomavirusvaksiner | |
CA2282497A1 (en) | In vitro peptide or protein expression library | |
DK0770679T3 (da) | HCV-specifikke peptider, præparater indeholdende dem og anvendelse deraf | |
BR9509001A (pt) | Proteína que objetiva virions de HIV com base em moléculas de fusão HIV-1 VPR | |
DE69834908D1 (de) | Verfahren zur erhöhung der expression von endogenen oder exogenen genprodukten in pflanzen | |
PT698216E (pt) | Metodos de tipificacao do virus da hepatite c e reagentes para utilizar nestes | |
PT742821E (pt) | Processo de preparacao de uma biblioteca multicombinatoria de vectores de expressao de genes de anticorpos | |
HUP0000318A2 (hu) | Tumorvakcina és eljárás előállítására | |
EP1012603A4 (en) | FUNCTIONAL FRAGMENTS OF THE HIV-1 VPR PROTEIN AND METHODS OF USE | |
ATE273388T1 (de) | Veränderte menschliche c3-proteine | |
ES2232860T3 (es) | Proteinas recombinantes de ribonucleasa. | |
DK1082423T3 (da) | Cyclin E2-gener og -proteiner | |
BR0015287A (pt) | Moléculas recombinantes de fusão | |
EP0749312A4 (en) | DIROFILARIA IMMITIS - Gp29 - PROTEINS, NUCLEIC ACID MOLECULES AND THEIR USE | |
ES2175184T3 (es) | Virus que expresan proteinas toxicas y leneas celulares productoras. | |
DK0941252T3 (da) | Enkeltkædede anti-P53-antistoffragmenter og anvendelse heraf | |
ES2073451T3 (es) | Vectores de clonacion y de expresion en una cepa de actinomiceto, procedimiento de transformacion de dicha cepa, cepa de actinomiceto obtenida y preparacion de proteinas. | |
ATE194648T1 (de) | Verfahren zur inaktivierung von viren in präparationen von proteinen | |
ATE301721T1 (de) | In vivo herstellung von replicativen molekülen | |
DE69533905D1 (de) | Interferon alpha/beta bindendes Protein, seine Herstellung und Anwendung | |
KR890008166A (ko) | 융합 단백질의 선택적 분해 방법 | |
HUP0104254A2 (hu) | Ezrin szabályozó/kihajtogató peptidek | |
EP0846165A4 (en) | NOVEL PROTEINS AND NUCLEIC ACID MOLECULES OF FILARIID NEMATODE CYSTEIN PROTEASE AND THEIR USE |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
Ref document number: 870050 Country of ref document: ES |