DE69621949T2 - Toxisches protein exprimierende viren und produktionszellinien - Google Patents
Toxisches protein exprimierende viren und produktionszellinienInfo
- Publication number
- DE69621949T2 DE69621949T2 DE69621949T DE69621949T DE69621949T2 DE 69621949 T2 DE69621949 T2 DE 69621949T2 DE 69621949 T DE69621949 T DE 69621949T DE 69621949 T DE69621949 T DE 69621949T DE 69621949 T2 DE69621949 T2 DE 69621949T2
- Authority
- DE
- Germany
- Prior art keywords
- cell lines
- production cell
- toxic protein
- expressing viruses
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
- C12N2740/13041—Use of virus, viral particle or viral elements as a vector
- C12N2740/13043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
- C12N2760/20222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
- C12N2830/002—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor
- C12N2830/003—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor tet inducible
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/10—Vectors comprising a special translation-regulating system regulates levels of translation
- C12N2840/105—Vectors comprising a special translation-regulating system regulates levels of translation enhancing translation
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US58055695A | 1995-12-29 | 1995-12-29 | |
US58055495A | 1995-12-29 | 1995-12-29 | |
PCT/US1996/020587 WO1997024452A2 (en) | 1995-12-29 | 1996-12-20 | Toxic-protein expressing viruses and producer cell lines |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69621949D1 DE69621949D1 (de) | 2002-08-01 |
DE69621949T2 true DE69621949T2 (de) | 2002-09-26 |
Family
ID=27078078
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69621949T Expired - Fee Related DE69621949T2 (de) | 1995-12-29 | 1996-12-20 | Toxisches protein exprimierende viren und produktionszellinien |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0870050B1 (de) |
JP (1) | JP2000502261A (de) |
AT (1) | ATE219521T1 (de) |
DE (1) | DE69621949T2 (de) |
DK (1) | DK0870050T3 (de) |
ES (1) | ES2175184T3 (de) |
PT (1) | PT870050E (de) |
WO (1) | WO1997024452A2 (de) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2337520B (en) * | 1998-05-22 | 2000-06-14 | Oxford Biomedica Ltd | Delivery system |
KR20010079671A (ko) * | 1998-08-20 | 2001-08-22 | 스티븐 에이. 서윈. 엠.디. | 재조합 유전자 생성물을 생성시키는 동안 세포독성을조절하는 억제 tRNA의 용도 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4963481A (en) * | 1985-12-18 | 1990-10-16 | Genetics Institute Inc | Promoter system |
US5512421A (en) * | 1991-02-19 | 1996-04-30 | The Regents Of The University Of California | Generation, concentration and efficient transfer of VSV-G pseudotyped retroviral vectors |
-
1996
- 1996-12-20 ES ES96945414T patent/ES2175184T3/es not_active Expired - Lifetime
- 1996-12-20 EP EP96945414A patent/EP0870050B1/de not_active Expired - Lifetime
- 1996-12-20 AT AT96945414T patent/ATE219521T1/de not_active IP Right Cessation
- 1996-12-20 JP JP09523909A patent/JP2000502261A/ja not_active Ceased
- 1996-12-20 DE DE69621949T patent/DE69621949T2/de not_active Expired - Fee Related
- 1996-12-20 PT PT96945414T patent/PT870050E/pt unknown
- 1996-12-20 WO PCT/US1996/020587 patent/WO1997024452A2/en active IP Right Grant
- 1996-12-20 DK DK96945414T patent/DK0870050T3/da active
Also Published As
Publication number | Publication date |
---|---|
DK0870050T3 (da) | 2002-07-15 |
EP0870050B1 (de) | 2002-06-19 |
ES2175184T3 (es) | 2002-11-16 |
EP0870050A2 (de) | 1998-10-14 |
ATE219521T1 (de) | 2002-07-15 |
WO1997024452A3 (en) | 1997-11-06 |
PT870050E (pt) | 2002-10-31 |
DE69621949D1 (de) | 2002-08-01 |
WO1997024452A2 (en) | 1997-07-10 |
JP2000502261A (ja) | 2000-02-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |