ES2174995T3 - Procedimiento para la preparacion de acidos carboxilicos de heterociclos aromaticos con contenido en nitrogeno. - Google Patents
Procedimiento para la preparacion de acidos carboxilicos de heterociclos aromaticos con contenido en nitrogeno.Info
- Publication number
- ES2174995T3 ES2174995T3 ES96107208T ES96107208T ES2174995T3 ES 2174995 T3 ES2174995 T3 ES 2174995T3 ES 96107208 T ES96107208 T ES 96107208T ES 96107208 T ES96107208 T ES 96107208T ES 2174995 T3 ES2174995 T3 ES 2174995T3
- Authority
- ES
- Spain
- Prior art keywords
- aromatic
- heterocicles
- nitrogen
- procedure
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B43/00—Formation or introduction of functional groups containing nitrogen
- C07B43/06—Formation or introduction of functional groups containing nitrogen of amide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/84—Nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Quinoline Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
SE DESCRIBE UN PROCEDIMIENTO PARA LA OBTENCION DE ACIDOS CARBOXILICOS DE HETEROCICLOS AROMATICOS CON NITROGENO POR HIDROLISIS ALCALINA DE DE CARBOXAMIDAS DE LOS CORRESPONDIENTES N-HETEROCICLOS. LAS CARBOXAMIDAS SE OBTIENEN A PARTIR DE LOS NHETEROCICLOS HACIENDOLOS REACCIONAR CON FORMAMIDA EN PRESENCIA DE ACIDO PEROXODISULFURICO O DE UN PEROXODISULFATO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH163093 | 1993-06-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2174995T3 true ES2174995T3 (es) | 2002-11-16 |
Family
ID=4214940
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES94108389T Expired - Lifetime ES2099994T3 (es) | 1993-06-01 | 1994-05-31 | Procedimiento para la preparacion de carboxamidas de heterociclos aromaticos con contenido en nitrogeno. |
ES96107208T Expired - Lifetime ES2174995T3 (es) | 1993-06-01 | 1994-05-31 | Procedimiento para la preparacion de acidos carboxilicos de heterociclos aromaticos con contenido en nitrogeno. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES94108389T Expired - Lifetime ES2099994T3 (es) | 1993-06-01 | 1994-05-31 | Procedimiento para la preparacion de carboxamidas de heterociclos aromaticos con contenido en nitrogeno. |
Country Status (10)
Country | Link |
---|---|
US (1) | US5614636A (es) |
EP (2) | EP0627422B1 (es) |
JP (2) | JP3493727B2 (es) |
AT (2) | ATE151417T1 (es) |
CA (2) | CA2539969C (es) |
DE (2) | DE59410101D1 (es) |
DK (2) | DK0627422T3 (es) |
ES (2) | ES2099994T3 (es) |
GR (1) | GR3023095T3 (es) |
PT (1) | PT728744E (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE59711086D1 (de) * | 1996-03-21 | 2004-01-22 | Lonza Ag | Verfahren zur Herstellung von Arylamiden Heteroaromatischer Carbonsäuren |
SK283920B6 (sk) * | 1996-03-28 | 2004-05-04 | Lonza Ag | Spôsob výroby arylamidov heteroaromatických karboxylových kyselín |
DE59701125D1 (de) * | 1996-05-09 | 2000-03-23 | Lonza Ag | Verfahren zur Herstellung von Arylamiden heteroaromatischer Carbonsäuren |
US5900484A (en) * | 1996-09-18 | 1999-05-04 | Lonza Ag | Process for the preparation of arylamides of heteroaromatic carboxylic acids |
CA2209392C (en) * | 1996-07-23 | 2007-02-20 | Yves Bessard | Process for preparing pyridinecarboxylic esters |
CN110981795B (zh) * | 2019-12-18 | 2021-02-12 | 武汉世纪久海检测技术有限公司 | 一种利用2-氰基异烟酸甲酯制备2-氨酰基异烟酸的方法 |
CN115477638A (zh) * | 2022-10-09 | 2022-12-16 | 浙江神洲药业有限公司 | 一种托匹司他的制备方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2780624A (en) * | 1953-01-29 | 1957-02-05 | American Cyanamid Co | Process of producing pyrazinamide |
BE759237A (fr) * | 1969-11-21 | 1971-05-01 | Montedison Spa | Procede de preparation d'amides a partir de composes heterocycliques azotes |
JPS5817462B2 (ja) * | 1974-09-11 | 1983-04-07 | 昭和電工株式会社 | ピリジンカルボンサンアミド ノ セイゾウホウ |
US4496736A (en) * | 1981-06-23 | 1985-01-29 | Bayer Aktiengesellschaft | Process for the preparation of carboxylic acids and N-tert.-alkylamines |
-
1994
- 1994-05-17 CA CA002539969A patent/CA2539969C/en not_active Expired - Fee Related
- 1994-05-17 CA CA002123731A patent/CA2123731C/en not_active Expired - Fee Related
- 1994-05-27 US US08/250,576 patent/US5614636A/en not_active Expired - Lifetime
- 1994-05-30 JP JP11656294A patent/JP3493727B2/ja not_active Expired - Fee Related
- 1994-05-31 DE DE59410101T patent/DE59410101D1/de not_active Expired - Fee Related
- 1994-05-31 DK DK94108389.1T patent/DK0627422T3/da active
- 1994-05-31 ES ES94108389T patent/ES2099994T3/es not_active Expired - Lifetime
- 1994-05-31 DE DE59402341T patent/DE59402341D1/de not_active Expired - Fee Related
- 1994-05-31 EP EP94108389A patent/EP0627422B1/de not_active Expired - Lifetime
- 1994-05-31 EP EP96107208A patent/EP0728744B1/de not_active Expired - Lifetime
- 1994-05-31 AT AT94108389T patent/ATE151417T1/de not_active IP Right Cessation
- 1994-05-31 AT AT96107208T patent/ATE215933T1/de not_active IP Right Cessation
- 1994-05-31 ES ES96107208T patent/ES2174995T3/es not_active Expired - Lifetime
- 1994-05-31 PT PT96107208T patent/PT728744E/pt unknown
- 1994-05-31 DK DK96107208T patent/DK0728744T3/da active
-
1997
- 1997-04-10 GR GR970400599T patent/GR3023095T3/el unknown
-
2003
- 2003-09-02 JP JP2003310018A patent/JP3858876B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE59410101D1 (de) | 2002-05-16 |
PT728744E (pt) | 2002-09-30 |
JP2004043491A (ja) | 2004-02-12 |
DE59402341D1 (de) | 1997-05-15 |
CA2123731A1 (en) | 1994-12-02 |
DK0728744T3 (da) | 2002-07-29 |
DK0627422T3 (es) | 1997-05-05 |
ATE215933T1 (de) | 2002-04-15 |
EP0728744B1 (de) | 2002-04-10 |
GR3023095T3 (en) | 1997-07-30 |
JP3493727B2 (ja) | 2004-02-03 |
CA2123731C (en) | 2006-07-11 |
EP0627422A3 (de) | 1995-03-22 |
EP0728744A3 (de) | 1996-11-27 |
ATE151417T1 (de) | 1997-04-15 |
CA2539969A1 (en) | 1994-12-02 |
JP3858876B2 (ja) | 2006-12-20 |
JPH06340632A (ja) | 1994-12-13 |
CA2539969C (en) | 2009-07-07 |
ES2099994T3 (es) | 1997-06-01 |
EP0627422A2 (de) | 1994-12-07 |
EP0627422B1 (de) | 1997-04-09 |
US5614636A (en) | 1997-03-25 |
EP0728744A2 (de) | 1996-08-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP0326151A3 (en) | Improved controlled release formulation | |
IL91309A (en) | Transformed filamentous fungus and its use for production of proteins | |
NO924978D0 (no) | Chinolon- og naftyridon-karboksylsyrederivater | |
ES2174995T3 (es) | Procedimiento para la preparacion de acidos carboxilicos de heterociclos aromaticos con contenido en nitrogeno. | |
AU8052094A (en) | Novel retinoid conjugate compounds and methods for treating skin aging | |
DK0611767T3 (da) | Heterocyclisk substituerede phenylcyclohexancarboxylsyrederivater som angiotension II-antagonister | |
AR034936A1 (es) | Procedimiento flexible para la obtencion conjunta de acido formico y un acido carboxilico con por lo menos dos atomos de carbono y/o sus derivados. | |
ATE113599T1 (de) | Heterozyklisch substituierte chinolincarbonsäure. | |
DE59709031D1 (de) | Stabile wässrige formulierung von 3-(n-butylacetamino)-propionsäureethylester | |
CA2170486A1 (en) | Synthesis of Amido Acids from Carboxylic Acids and Lactams | |
DE50215007D1 (de) | Verfahren zur Herstellung von Anhydriden ungesättiger Carbonsäuren | |
DE59308469D1 (de) | Fluorierte Carbonsäureester von Phosphono- und Phosphinocarbonsäuren sowie deren Verwendung | |
EP0359087A3 (en) | Proteolytic perhydrolysis system and method of use for bleaching | |
NZ242279A (en) | Enzymatic hydrolysis of carboxylic acid derivatives using an organic solvent and saturating the solution with water | |
EP0563729A3 (en) | Alkenylaminoalkane-1,1-disphosphonic acid derivatives and its copolymers with unsaturated carboxylic acids | |
BR0004064A (pt) | Processos para a preparação de um éster carboxilato de arila, e para a preparação de uma mistura de ésteres carboxilato de arila | |
DK0610697T3 (da) | Imidazolyl-substituerede phenyleddikesyreprolinamider. | |
ES2148689T3 (es) | Procedimiento para producir acido 2-hidroxi-4-arilbutirico opticamente activo, o su ester, e intermedio para su preparacion. | |
IT1230706B (it) | Derivati dell'acido 3 piroglutamoil tiazolidin 4 carbossilico e loro proprieta' farmacologiche. | |
DE59401050D1 (de) | Salze von Copolymeren aus ethylenisch ungesättigten Carbonsäuren und ethylenisch ungesättigten Fettsäurederivaten | |
MY132151A (en) | Novel carboxylic acid derivatives, their preparation and use | |
DE69333132D1 (de) | Stabilisierte Copolymere des Ethylens mit ethylenisch ungesättigten Carbonsäuren | |
ES8605228A1 (es) | Procedimiento de preparacion de 1-naftiltioamidas | |
NO961640L (no) | Stabilt farmasöytisk preparat av terfenadin og ibuprofen | |
DE3774829D1 (de) | Verfahren zur herstellung von polymaleinsaeureanhydridpulver. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
Ref document number: 728744 Country of ref document: ES |