ES2174073T3 - Forma farmaceutica solida para uso oral. - Google Patents
Forma farmaceutica solida para uso oral.Info
- Publication number
- ES2174073T3 ES2174073T3 ES96918678T ES96918678T ES2174073T3 ES 2174073 T3 ES2174073 T3 ES 2174073T3 ES 96918678 T ES96918678 T ES 96918678T ES 96918678 T ES96918678 T ES 96918678T ES 2174073 T3 ES2174073 T3 ES 2174073T3
- Authority
- ES
- Spain
- Prior art keywords
- administration
- solid pharmaceutical
- ingrediently
- easily soluble
- active ingredient
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000007787 solid Substances 0.000 title abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- 230000003111 delayed effect Effects 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 238000012423 maintenance Methods 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 230000002035 prolonged effect Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
POR COMBINACION DEL MISMO INGREDIENTE ACTIVO EN UNA FORMA FACILMENTE SOLUBLE EN AGUA O EN LIQUIDOS ACUOSOS Y EN UNA FORMA DE LIBERACION DEMORADA Y PROGRAMABLE EN LA MISMA FORMA FARMACEUTICA SOLIDA PARA ADMINISTRACION ORAL, PREFERENTEMENTE EN FORMA DE UNA TABLETA DE DOBLE CAPA, SE OBTIENEN ELEVADOS NIVELES PLASMATICOS INMEDIATAMENTE DESPUES DE LA ADMINISTRACION, CON LO QUE SE CONSIGUE UN RAPIDO EFECTO TERAPEUTICO Y EL MANTENIMIENTO DE ELEVADOS NIVELES PLASMATICOS DURANTE UN PERIODO PROLONGADO DE TIEMPO TRAS LA ADMINISTRACION. LAS DOS FORMAS DE INGREDIENTES ACTIVOS VAN ACOMPAÑADAS POR LOS APROPIADOS ADYUVANTES Y EXCIPIENTES QUE SON CAPACES DE PRODUCIR LA RAPIDA DISGREGACION DE LA CAPA QUE CONTIENE EL INGREDIENTE ACTIVO EN UNA FORMA FACILMENTE SOLUBLE Y LA LIBERACION DEMORADA DEL INGREDIENTE ACTIVO EN LA FORMA DE LIBERACION DEMORADA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT95MI001223A IT1276689B1 (it) | 1995-06-09 | 1995-06-09 | Forma farmaceutica solida ad uso orale |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2174073T3 true ES2174073T3 (es) | 2002-11-01 |
Family
ID=11371782
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES96918678T Expired - Lifetime ES2174073T3 (es) | 1995-06-09 | 1996-06-05 | Forma farmaceutica solida para uso oral. |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP0833618B1 (es) |
KR (1) | KR19990021897A (es) |
AT (1) | ATE215816T1 (es) |
CA (1) | CA2224267A1 (es) |
DE (1) | DE69620606T2 (es) |
ES (1) | ES2174073T3 (es) |
IT (1) | IT1276689B1 (es) |
PT (1) | PT833618E (es) |
WO (1) | WO1996041617A1 (es) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6486177B2 (en) | 1995-12-04 | 2002-11-26 | Celgene Corporation | Methods for treatment of cognitive and menopausal disorders with D-threo methylphenidate |
US5837284A (en) | 1995-12-04 | 1998-11-17 | Mehta; Atul M. | Delivery of multiple doses of medications |
TW430561B (en) * | 1995-12-20 | 2001-04-21 | Gea Farmaceutisk Fabrik As | Rapid release tablet composition comprising tolfenamic acid or a pharmaceutically acceptable salt thereof as active ingredient and a method of preparing such tablet |
US6638948B1 (en) * | 1996-09-09 | 2003-10-28 | Pentech Pharmaceuticals, Inc. | Amorphous paroxetine composition |
US6261537B1 (en) | 1996-10-28 | 2001-07-17 | Nycomed Imaging As | Diagnostic/therapeutic agents having microbubbles coupled to one or more vectors |
DE19816070A1 (de) | 1998-04-09 | 1999-10-14 | Aventis Res & Tech Gmbh & Co | Retardtablette hergestellt aus linearen wasserunlöslichen Polysacchariden |
EP1064937A1 (en) * | 1999-06-28 | 2001-01-03 | Sanofi-Synthelabo | Timed dual release dosage forms comprising a short acting hypnotic or a salt thereof |
IT1313590B1 (it) * | 1999-08-03 | 2002-09-09 | Formenti Farmaceutici Spa | Composizioni a rilascio controllato di acido acetilsalicilico. |
DE19954421A1 (de) * | 1999-11-12 | 2001-05-31 | Lohmann Therapie Syst Lts | Filmförmige Zubereitung zur biphasigen Freisetzung pharmakologisch wirksamer oder anderer Substanzen |
KR100446829B1 (ko) * | 2002-02-20 | 2004-09-04 | 한국유나이티드제약 주식회사 | 가용화된 피록시캄을 함유한 확산형 정제의 조성물 및그의 제조방법 |
BR0318201A (pt) | 2003-03-21 | 2006-03-21 | Mcneil Ppc Inc | regime de dosagem de fármaco antiinflamatório não-esteroidal |
US20040186180A1 (en) | 2003-03-21 | 2004-09-23 | Gelotte Cathy K. | Non-steroidal anti-inflammatory drug dosing regimen |
AU2013267036B2 (en) * | 2003-03-21 | 2016-05-26 | Mcneil-Ppc, Inc. | Non-steroidal anti-inflammatory drug dosing regimen |
GB0501809D0 (en) * | 2005-01-28 | 2005-03-09 | Pharmakodex Ltd | Anti-migraine formulations |
CN101111242A (zh) * | 2005-01-31 | 2008-01-23 | 协和发酵工业株式会社 | 含有鸟氨酸盐酸盐的片剂 |
KR20170123724A (ko) | 2006-03-28 | 2017-11-08 | 자블린 파머슈티칼스 인코포레이티드 | 저 투여량의 디클로페낙 및 베타-사이클로덱스트린 제형 |
WO2009021127A2 (en) * | 2007-08-07 | 2009-02-12 | Neurogen Corporation | Controlled released compositions |
JP5345620B2 (ja) | 2007-08-15 | 2013-11-20 | マクニール−ピーピーシー・インコーポレーテツド | 即時放出及び徐放型イブプロフェンの投与法 |
EP2250149B1 (en) | 2008-02-08 | 2019-09-18 | Colgate-Palmolive Company | Method for the production of arginine bicarbonate |
CN101938985A (zh) | 2008-02-08 | 2011-01-05 | 高露洁-棕榄公司 | 组合物和装置 |
EP2255797A4 (en) * | 2008-02-22 | 2011-09-07 | Hanall Biopharma Co Ltd | COMPOSITE PREPARATION |
BR112012013930A2 (pt) | 2009-12-18 | 2016-06-07 | Colgate Palmolive Co | métodos para produção de bicarbonato de arginina em baixa pressão |
MY157789A (en) | 2009-12-18 | 2016-07-29 | Colgate Palmolive Co | Methods for production of high concentration of arginine bicarbonate solution at high pressure |
KR101320802B1 (ko) * | 2010-02-16 | 2013-10-23 | 주식회사 드림파마 | 방출 제어형 사포그릴레이트 염산염 함유 다층 정제 |
US10905652B2 (en) | 2011-03-23 | 2021-02-02 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
US9283214B2 (en) | 2011-03-23 | 2016-03-15 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
EP4011364B1 (en) | 2011-03-23 | 2023-12-13 | Ironshore Pharmaceuticals & Development, Inc. | Methods and compositions for treatment of attention deficit disorder |
US10292937B2 (en) | 2011-03-23 | 2019-05-21 | Ironshore Pharmaceuticals & Development, Inc. | Methods of treatment of attention deficit hyperactivity disorder |
US9603809B2 (en) | 2011-03-23 | 2017-03-28 | Ironshore Pharmaceuticals & Development, Inc. | Methods of treatment of attention deficit hyperactivity disorder |
US8916588B2 (en) | 2011-03-23 | 2014-12-23 | Ironshore Pharmaceuticals & Development, Inc. | Methods for treatment of attention deficit hyperactivity disorder |
US9498447B2 (en) | 2011-03-23 | 2016-11-22 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
US9119809B2 (en) | 2011-03-23 | 2015-09-01 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
US11241391B2 (en) | 2011-03-23 | 2022-02-08 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
US8927010B2 (en) | 2011-03-23 | 2015-01-06 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
KR102124459B1 (ko) | 2018-05-02 | 2020-06-23 | 주식회사 에코앤휴먼 | 종패 부착용 식생부 및 이를 포함하는 인공어초 |
CN110037994B (zh) * | 2019-05-24 | 2022-04-12 | 中国药科大学 | 一种布洛芬速释缓释双层片及其制备方法 |
CN114983973B (zh) * | 2022-05-31 | 2023-05-05 | 石家庄四药有限公司 | 一种乌拉地尔缓释胶囊及其制备方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4806359A (en) * | 1987-04-22 | 1989-02-21 | Mcneilab, Inc. | Iburprofen sustained release matrix and process |
US5032406A (en) * | 1989-02-21 | 1991-07-16 | Norwich Eaton Pharmaceuticals, Inc. | Dual-action tablet |
US5204116A (en) * | 1991-05-01 | 1993-04-20 | Alza Corporation | Dosage form providing immediate therapy followed by prolonged therapy |
FI93924C (fi) * | 1991-09-17 | 1995-06-26 | Martti Lauri Antero Marvola | Menetelmä säädellysti lääkeainetta vapauttavan valmisteen valmistamiseksi |
US5609884A (en) * | 1992-08-31 | 1997-03-11 | G. D. Searle & Co. | Controlled release naproxen sodium plus naproxen combination tablet |
IT1255522B (it) * | 1992-09-24 | 1995-11-09 | Ubaldo Conte | Compressa per impiego terapeutico atta a cedere una o piu' sostanze attive con differenti velocita' |
IT1264696B1 (it) * | 1993-07-09 | 1996-10-04 | Applied Pharma Res | Forme farmaceutiche destinate alla somministrazione orale in grado di rilasciare sostanze attive a velocita' controllata e differenziata |
-
1995
- 1995-06-09 IT IT95MI001223A patent/IT1276689B1/it active IP Right Grant
-
1996
- 1996-06-05 KR KR1019970708372A patent/KR19990021897A/ko not_active Application Discontinuation
- 1996-06-05 AT AT96918678T patent/ATE215816T1/de not_active IP Right Cessation
- 1996-06-05 PT PT96918678T patent/PT833618E/pt unknown
- 1996-06-05 EP EP96918678A patent/EP0833618B1/en not_active Expired - Lifetime
- 1996-06-05 WO PCT/EP1996/002495 patent/WO1996041617A1/en active IP Right Grant
- 1996-06-05 DE DE69620606T patent/DE69620606T2/de not_active Expired - Lifetime
- 1996-06-05 ES ES96918678T patent/ES2174073T3/es not_active Expired - Lifetime
- 1996-06-05 CA CA002224267A patent/CA2224267A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
KR19990021897A (ko) | 1999-03-25 |
WO1996041617A1 (en) | 1996-12-27 |
EP0833618B1 (en) | 2002-04-10 |
DE69620606D1 (de) | 2002-05-16 |
ITMI951223A1 (it) | 1996-12-09 |
IT1276689B1 (it) | 1997-11-03 |
PT833618E (pt) | 2002-09-30 |
EP0833618A1 (en) | 1998-04-08 |
ITMI951223A0 (it) | 1995-06-09 |
ATE215816T1 (de) | 2002-04-15 |
CA2224267A1 (en) | 1996-12-27 |
DE69620606T2 (de) | 2002-10-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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