ES2173862T3 - Ligandos de aminocarboxilato que tienen restos amidicos aromaticos sustituidos. - Google Patents

Ligandos de aminocarboxilato que tienen restos amidicos aromaticos sustituidos.

Info

Publication number
ES2173862T3
ES2173862T3 ES92307091T ES92307091T ES2173862T3 ES 2173862 T3 ES2173862 T3 ES 2173862T3 ES 92307091 T ES92307091 T ES 92307091T ES 92307091 T ES92307091 T ES 92307091T ES 2173862 T3 ES2173862 T3 ES 2173862T3
Authority
ES
Spain
Prior art keywords
substituted aromatic
amidic
remains
aminocarboxylate ligands
aminocarboxylate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92307091T
Other languages
English (en)
Inventor
Radhakrishna Pillai
Edmund R Marinelli
Michael F Tweedle
Ramachandran S Ranganathan
Sang-Ihn Kang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bracco International BV
Original Assignee
Bracco International BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco International BV filed Critical Bracco International BV
Application granted granted Critical
Publication of ES2173862T3 publication Critical patent/ES2173862T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0474Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0478Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0474Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0482Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

SE PRESENTAN COMPLEJOS DE METAL-QUELATO QUE COMPRENDEN LIGANTES DE AMINOCARBOXILATO QUE INCLUYEN MOLECULAS DE AMIDO AROMATICO SUBSTITUIDO, TALES COMO LAS QUE TIENEN LA FORMULA EN LA QUE R13, A1, R1 Y R2 SE DEFINEN EN LAS ESPECIFICACIONES.
ES92307091T 1991-08-01 1992-08-03 Ligandos de aminocarboxilato que tienen restos amidicos aromaticos sustituidos. Expired - Lifetime ES2173862T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US73899891A 1991-08-01 1991-08-01

Publications (1)

Publication Number Publication Date
ES2173862T3 true ES2173862T3 (es) 2002-11-01

Family

ID=24970389

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92307091T Expired - Lifetime ES2173862T3 (es) 1991-08-01 1992-08-03 Ligandos de aminocarboxilato que tienen restos amidicos aromaticos sustituidos.

Country Status (17)

Country Link
EP (1) EP0543482B1 (es)
JP (1) JP2538165B2 (es)
KR (1) KR930003911A (es)
CN (1) CN1069027A (es)
AT (1) ATE212861T1 (es)
AU (1) AU2061592A (es)
CA (1) CA2074867A1 (es)
DE (1) DE69232408T2 (es)
ES (1) ES2173862T3 (es)
FI (1) FI923470A (es)
HU (1) HUT62906A (es)
IL (1) IL102570A0 (es)
MX (1) MX9204434A (es)
NO (1) NO305126B1 (es)
PL (1) PL295490A1 (es)
TW (1) TW213864B (es)
ZA (1) ZA925521B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5310535A (en) * 1992-04-24 1994-05-10 The Dow Chemical Company Carboxamide modified polyamine chelators and radioactive complexes thereof for conjugation to antibodies
WO1995027705A1 (en) * 1994-04-08 1995-10-19 Bracco International B.V. Aromatic amide compounds and metal chelates thereof
TW319763B (es) 1995-02-01 1997-11-11 Epix Medical Inc
DE60016898T2 (de) * 1999-02-18 2006-03-30 The Regents Of The University Of California, Oakland Phthalamid-lanthanid komplexe zur verwendung als lumineszenzmarker
FR2802928B1 (fr) * 1999-12-22 2003-01-31 Air Liquide Polyazacycloalcanes eventuellement greffes sur une matrice solide, complexes organometalliques les incorporant comme ligands. utilisation desdits composes a l'extraction de metaux lourds
EP1289571B1 (en) * 2000-05-12 2004-07-21 University Hospital Prochelators of radiometal labeled molecules
FR2827515B1 (fr) * 2001-07-20 2005-06-03 Oreal Composition moussante a base de silice et de polymere cationique
BRPI0619198A2 (pt) * 2005-12-02 2011-09-20 Ge Healthcare As composto, composição, uso da composição, e, métodos para formação de imagem por rm e/ou de espectroscopia por rm, e para a preparação de compostos
EP2774611A4 (en) * 2011-10-06 2015-03-04 Ihi Corp MAGNETIC COMPOSITION AND METHOD FOR THE PRODUCTION THEREOF
CN103073667B (zh) * 2013-01-25 2016-05-11 南京大学 一种双伯胺基螯合树脂及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03203282A (ja) * 1989-12-29 1991-09-04 Nec Kansai Ltd 半導体レーザダイオード
JP2776953B2 (ja) * 1990-04-10 1998-07-16 日本メジフィジックス株式会社 多官能性金属キレート化合物とその用途
DE4035760A1 (de) * 1990-11-08 1992-05-14 Schering Ag Mono-n-substituierte 1,4,7,10-tetraazacyclododecan-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
JP2807852B2 (ja) * 1991-07-18 1998-10-08 株式会社ミドリ十字 新規キレート化剤、該キレート化剤と金属原子との錯化合物及びそれを含む診断剤

Also Published As

Publication number Publication date
PL295490A1 (en) 1993-05-31
IL102570A0 (en) 1993-01-14
DE69232408D1 (de) 2002-03-21
ATE212861T1 (de) 2002-02-15
HU9202513D0 (en) 1992-10-28
FI923470A (fi) 1993-02-02
EP0543482A1 (en) 1993-05-26
JP2538165B2 (ja) 1996-09-25
HUT62906A (en) 1993-06-28
TW213864B (es) 1993-10-01
AU2061592A (en) 1993-02-04
ZA925521B (en) 1993-04-28
CA2074867A1 (en) 1993-02-02
FI923470A0 (fi) 1992-07-31
JPH05208920A (ja) 1993-08-20
DE69232408T2 (de) 2002-09-19
NO923038D0 (no) 1992-07-31
NO923038L (no) 1993-02-02
EP0543482B1 (en) 2002-02-06
MX9204434A (es) 1994-06-30
CN1069027A (zh) 1993-02-17
KR930003911A (ko) 1993-03-22
NO305126B1 (no) 1999-04-06

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