ES2171542T3 - Aparato y tecnica de patch-clamp que tienen alta produccion y que requieren un pequeño volumen de fluido. - Google Patents

Aparato y tecnica de patch-clamp que tienen alta produccion y que requieren un pequeño volumen de fluido.

Info

Publication number
ES2171542T3
ES2171542T3 ES95923258T ES95923258T ES2171542T3 ES 2171542 T3 ES2171542 T3 ES 2171542T3 ES 95923258 T ES95923258 T ES 95923258T ES 95923258 T ES95923258 T ES 95923258T ES 2171542 T3 ES2171542 T3 ES 2171542T3
Authority
ES
Spain
Prior art keywords
utilizing
novel
tested
small amounts
high throughput
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95923258T
Other languages
English (en)
Inventor
S Ren-Peter Olesen
Palle Christophersen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sophion Bioscience AS
Original Assignee
Sophion Bioscience AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sophion Bioscience AS filed Critical Sophion Bioscience AS
Application granted granted Critical
Publication of ES2171542T3 publication Critical patent/ES2171542T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1095—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers
    • G01N35/1097—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers characterised by the valves
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10—Perfusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C12M33/04—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus by injection or suction, e.g. using pipettes, syringes, needles
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48—Automatic or computerized control
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
    • G01N33/48728—Investigating individual cells, e.g. by patch clamp, voltage clamp

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Computer Hardware Design (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Container, Conveyance, Adherence, Positioning, Of Wafer (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicinal Preparation (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)

Abstract

SE PRESENTA UNA APARATO PARA LLEVAR A CABO UNA TECNICA DE SUJECION DE PARCHES UTILIZADO EN EL ESTUDIO DEL EFECTO DE CIERTOS MATERIALES SOBRE LOS C ANALES DE TRANSFERENCIA DE IONES EN EL TEJIDO BIOLOGICO, Y MAS PARTICULARMENTE UN APARATO PARA LA SUJECION DE PARCHES QUE UTILIZA UN AUTOMUESTREADOR, TAL COMO AQUELLOS UTILIZADOS CON EL APARATO HPLC, PARA SUMINISTRAR UN ALTO RENDIMIENTO. LA INVENCION INCLUYE ADICIONALMENTE NUEVOS MONTAJES DE CAMARAS DE MICROPERFUSION CAPACES DE UTILIZAR SOLAMENTE PEQUEÑAS CANTIDADES DEL MATERIAL A COMPROBAR Y SOLAMENTE PEQUEÑAS CANTIDADES DE PORTADOR LIQUIDO, MEDIANTE LO CUAL SE HACE POSIBLE QUE SE COMPLETEN MUCHAS PRUEBAS EN UN CORTO PERIODO DE TIEMPO. LA INVENCION MAS AMPLIAMENTE SE REFIERE AL MANEJO Y LA DISPOSICION DE APLICACION DE NUEVAS DROGAS DE ELECTROFISIOLOGIA PARA SELECCIONAR SUBSTANCIAS QUIMICAS MIENTRAS QUE SE SUMINISTRA UN ALTO RENDIMIENTO Y SE REQUIERE SOLAMENTE UN PEQUEÑO VOLUMEN DE SOLUCIONES Y MUESTRAS A COMPROBAR. LA INVENCION TAMBIEN COMPRENDEVARIOS PROCEDIMIENTOS NUEVOS PARA UTILIZAR EL APARATO DE LA INVENCION.
ES95923258T 1994-10-28 1995-06-07 Aparato y tecnica de patch-clamp que tienen alta produccion y que requieren un pequeño volumen de fluido. Expired - Lifetime ES2171542T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK125294 1994-10-28

Publications (1)

Publication Number Publication Date
ES2171542T3 true ES2171542T3 (es) 2002-09-16

Family

ID=8102743

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95923258T Expired - Lifetime ES2171542T3 (es) 1994-10-28 1995-06-07 Aparato y tecnica de patch-clamp que tienen alta produccion y que requieren un pequeño volumen de fluido.

Country Status (12)

Country Link
US (2) US6063260A (es)
EP (1) EP0788600B1 (es)
JP (1) JP3688713B2 (es)
AT (1) ATE216080T1 (es)
AU (1) AU2788695A (es)
CA (1) CA2203886C (es)
DE (1) DE69526364T2 (es)
DK (1) DK0788600T3 (es)
ES (1) ES2171542T3 (es)
PT (1) PT788600E (es)
SI (1) SI0788600T1 (es)
WO (1) WO1996013721A1 (es)

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DE10008373C2 (de) * 2000-02-23 2002-11-28 Helmut Adelsberger Verfahren und Vorrichtung zur Bestimmung der Ionenkanalaktivität
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US7270730B2 (en) * 2000-08-04 2007-09-18 Essen Instruments, Inc. High-throughput electrophysiological measurement system
US7067046B2 (en) * 2000-08-04 2006-06-27 Essen Instruments, Inc. System for rapid chemical activation in high-throughput electrophysiological measurements
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US20050058990A1 (en) * 2001-03-24 2005-03-17 Antonio Guia Biochip devices for ion transport measurement, methods of manufacture, and methods of use
US20040146849A1 (en) * 2002-01-24 2004-07-29 Mingxian Huang Biochips including ion transport detecting structures and methods of use
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US8202439B2 (en) * 2002-06-05 2012-06-19 Panasonic Corporation Diaphragm and device for measuring cellular potential using the same, manufacturing method of the diaphragm
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Also Published As

Publication number Publication date
ATE216080T1 (de) 2002-04-15
US6117291A (en) 2000-09-12
DE69526364T2 (de) 2002-11-28
DE69526364D1 (de) 2002-05-16
JPH10509794A (ja) 1998-09-22
EP0788600B1 (en) 2002-04-10
CA2203886A1 (en) 1996-05-09
JP3688713B2 (ja) 2005-08-31
SI0788600T1 (en) 2002-06-30
US6063260A (en) 2000-05-16
AU2788695A (en) 1996-05-23
CA2203886C (en) 2003-09-02
DK0788600T3 (da) 2002-08-05
PT788600E (pt) 2002-07-31
WO1996013721A1 (en) 1996-05-09
EP0788600A1 (en) 1997-08-13

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