ES2169258T3 - Utilizacion de proteasa de subtilisina mutada en productos cosmeticos. - Google Patents
Utilizacion de proteasa de subtilisina mutada en productos cosmeticos.Info
- Publication number
- ES2169258T3 ES2169258T3 ES96929256T ES96929256T ES2169258T3 ES 2169258 T3 ES2169258 T3 ES 2169258T3 ES 96929256 T ES96929256 T ES 96929256T ES 96929256 T ES96929256 T ES 96929256T ES 2169258 T3 ES2169258 T3 ES 2169258T3
- Authority
- ES
- Spain
- Prior art keywords
- subtilisine
- muted
- protease
- cosmetic products
- type
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 108091005804 Peptidases Proteins 0.000 title abstract 3
- 239000004365 Protease Substances 0.000 title abstract 3
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 title abstract 2
- 239000002537 cosmetic Substances 0.000 title abstract 2
- 102000035195 Peptidases Human genes 0.000 abstract 1
- 150000001413 amino acids Chemical group 0.000 abstract 1
- 230000007794 irritation Effects 0.000 abstract 1
- 230000035772 mutation Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
- C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cosmetics (AREA)
- Detergent Compositions (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Abstract
SE REIVINDICA EL USO EN PRODUCTOS COSMETICOS DE UNA PROTEASA MUTADA DEL TIPO SUBTILISINA QUE LLEVA AL MENOS UNA MUTACION EN SU SECUENCIA DE AMINOACIDOS, QUE HACE QUE LA CARGA POSITIVA DISMINUYA O LA CARGA NEGATIVA AUMENTE EN LA REGION DE UNION AL SUBSTRATO DE LA MOLECULA. LAS PROTEASAS DE ESTE TIPO MUESTRAN UN POTENCIAL DE IRRITACION SORPRENDENTEMENTE PEQUEÑO PARA LA PIEL Y LAS MUCOSAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19530816A DE19530816A1 (de) | 1995-08-23 | 1995-08-23 | Verwendung von mutierter Subtilisin-Protease in kosmetischen Produkten |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2169258T3 true ES2169258T3 (es) | 2002-07-01 |
Family
ID=7770073
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES96929256T Expired - Lifetime ES2169258T3 (es) | 1995-08-23 | 1996-08-14 | Utilizacion de proteasa de subtilisina mutada en productos cosmeticos. |
Country Status (8)
Country | Link |
---|---|
US (1) | US6509021B1 (es) |
EP (1) | EP0845972B1 (es) |
JP (1) | JPH11512092A (es) |
AT (1) | ATE209888T1 (es) |
DE (2) | DE19530816A1 (es) |
DK (1) | DK0845972T3 (es) |
ES (1) | ES2169258T3 (es) |
WO (1) | WO1997007770A1 (es) |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2204105T3 (es) * | 1998-01-08 | 2004-04-16 | Cosmoferm B.V. | Aplicacion local de enzimas utilizando una pelicula susceptible de desprendimiento. |
US6495136B1 (en) | 1998-03-26 | 2002-12-17 | The Procter & Gamble Company | Proteases having modified amino acid sequences conjugated to addition moieties |
US6908757B1 (en) | 1998-03-26 | 2005-06-21 | The Procter & Gamble Company | Serine protease variants having amino acid deletions and substitutions |
CA2325568A1 (en) | 1998-03-26 | 1999-09-30 | The Procter & Gamble Company | Serine protease variants having amino acid substitutions |
DE19829789A1 (de) * | 1998-07-03 | 2000-01-05 | Beiersdorf Ag | Gegen Akne und entzündete Comedonen wirksame Zubereitungen enthaltend Serin-Proteasen und ein oder mehrere Calciumsalze |
DE19857543A1 (de) * | 1998-12-14 | 2000-06-15 | Henkel Kgaa | Verwendung von Protease in flüssigen bis gelförmigen Wasch- und Reinigungsmitteln |
AU6085800A (en) | 1999-07-22 | 2001-02-13 | Procter & Gamble Company, The | Subtilisin protease variants having amino acid substitutions in defined epitope regions |
JP2003516116A (ja) | 1999-07-22 | 2003-05-13 | ザ、プロクター、エンド、ギャンブル、カンパニー | 立体的に保護されたクリップ部位を有するプロテアーゼ抱合体 |
CN1373802A (zh) | 1999-07-22 | 2002-10-09 | 宝洁公司 | 在特定表位区域具有氨基酸缺失和取代的枯草杆菌蛋白酶变体 |
US6946128B1 (en) | 1999-07-22 | 2005-09-20 | The Procter & Gamble Company | Protease conjugates having sterically protected epitope regions |
DE10121463A1 (de) * | 2001-05-02 | 2003-02-27 | Henkel Kgaa | Neue Alkalische Protease-Varianten und Wasch- und Reinigungsmittel enthaltend diese neuen Alkalischen Protease-Varianten |
DE10153792A1 (de) * | 2001-10-31 | 2003-05-22 | Henkel Kgaa | Neue Alkalische Protease-Varianten und Wasch- und Reinigungsmittel enthaltend diese neuen Alkalischen Protease-Varianten |
DE10162728A1 (de) * | 2001-12-20 | 2003-07-10 | Henkel Kgaa | Neue Alkalische Protease aus Bacillus gibsonii (DSM 14393) und Wasch-und Reinigungsmittel enthaltend diese neue Alkalische Protease |
DE10162727A1 (de) * | 2001-12-20 | 2003-07-10 | Henkel Kgaa | Neue Alkalische Protease aus Bacillus gibsonii (DSM 14391) und Wasch-und Reinigungsmittel enthaltend diese neue Alkalische Protease |
DE10163884A1 (de) * | 2001-12-22 | 2003-07-10 | Henkel Kgaa | Neue Alkalische Protease aus Bacillus sp. (DSM 14392) und Wasch- und Reinigungsmittel enthaltend diese neue Alkalische Protease |
DE10163883A1 (de) * | 2001-12-22 | 2003-07-10 | Henkel Kgaa | Neue Alkalische Protease aus Bacillus sp. (DSM 14390) und Wasch- und Reinigungsmittel enthaltend diese neue Alkalische Protease |
US6835385B2 (en) * | 2002-06-14 | 2004-12-28 | Carol J. Buck | Compositions and methods for softening, thinning and removing hyperkeratotic tissue |
EP1694847B1 (en) | 2003-11-19 | 2012-06-13 | Danisco US Inc. | Serine proteases, nucleic acids encoding serine enzymes and vectors and host cells incorporating same |
US7985569B2 (en) | 2003-11-19 | 2011-07-26 | Danisco Us Inc. | Cellulomonas 69B4 serine protease variants |
DE10360805A1 (de) * | 2003-12-23 | 2005-07-28 | Henkel Kgaa | Neue Alkalische Protease und Wasch- und Reinigungsmittel, enthaltend diese neue Alkalische Protease |
DE102004019751A1 (de) * | 2004-04-23 | 2005-11-17 | Henkel Kgaa | Neue Alkalische Proteasen und Wasch- und Reinigungsmittel, enthaltend diese neuen Alkalischen Proteasen |
KR100558751B1 (ko) | 2004-10-18 | 2006-03-14 | 주식회사 태평양 | 피부보습용 화장료 조성물 |
FR2884711A1 (fr) * | 2005-04-26 | 2006-10-27 | Clarins Soc Par Actions Simpli | Composition cosmetique preparant la peau au rasage |
FR2884710A1 (fr) * | 2005-04-26 | 2006-10-27 | Clarins Soc Par Actions Simpli | Composition cosmetique preparant la peau au rasage |
EP2032698B1 (en) | 2006-06-23 | 2012-06-27 | Danisco US Inc. | Systematic evaluation of sequence and activity relationships using site evaluation libraries for engineering multiple properties |
BRPI0717515A2 (pt) * | 2006-10-16 | 2013-11-19 | Danisco Us Inc Genencor Div | Detergentes de louças sem fosfatos |
DE102007003143A1 (de) | 2007-01-16 | 2008-07-17 | Henkel Kgaa | Neue Alkalische Protease aus Bacillus gibsonii und Wasch- und Reinigungsmittel enthaltend diese neue Alkalische Protease |
DE102007032111B4 (de) | 2007-07-09 | 2017-07-20 | Henkel Ag & Co. Kgaa | Neue Proteasen und Wasch- und Reinigungsmittel enthaltend diese Proteasen |
DE102007036756A1 (de) | 2007-08-03 | 2009-02-05 | Henkel Ag & Co. Kgaa | Neue Proteasen und Wasch- und Reinigungsmittel, enthaltend diese neuen Proteasen |
DE102007049830A1 (de) | 2007-10-16 | 2009-04-23 | Henkel Ag & Co. Kgaa | Neue Proteinvarianten durch zirkulare Permutation |
DE102007051092A1 (de) | 2007-10-24 | 2009-04-30 | Henkel Ag & Co. Kgaa | Subtilisin aus Becillus pumilus und Wasch- und Reinigungsmittel enthaltend dieses neue Subtilisin |
US7618801B2 (en) | 2007-10-30 | 2009-11-17 | Danison US Inc. | Streptomyces protease |
EP2947147A3 (en) | 2008-06-06 | 2015-12-23 | Danisco US Inc. | Compositions and methods comprising variant microbial proteases |
US8753861B2 (en) | 2008-11-11 | 2014-06-17 | Danisco Us Inc. | Protease comprising one or more combinable mutations |
AR073420A1 (es) | 2008-11-11 | 2010-11-03 | Danisco Us Inc | Variantes de serina proteasas, composiciones y metodos de limpieza que las comprenden |
DE102009029513A1 (de) * | 2009-09-16 | 2011-03-24 | Henkel Ag & Co. Kgaa | Lagerstabiles flüssiges Wasch- oder Reinigungsmittel enthaltend Proteasen |
PL2558573T3 (pl) | 2010-04-15 | 2017-08-31 | Danisco Us Inc. | Kompozycje i sposoby obejmujące warianty proteazy |
JP6448904B2 (ja) | 2010-05-06 | 2019-01-09 | ダニスコ・ユーエス・インク | サブチリシン変異体を含む組成物及び方法 |
CN106065381B (zh) | 2011-05-05 | 2019-07-26 | 宝洁公司 | 包含丝氨酸蛋白酶变体的组合物和方法 |
CA3111256C (en) | 2011-05-05 | 2023-05-09 | Danisco Us Inc. | Compositions and methods comprising serine protease variants |
DE102012201522A1 (de) * | 2012-02-02 | 2013-08-08 | Basf Se | Lagerstabiles flüssiges Geschirrspülmittel enthaltend Protease und Amylase |
DE102013219467A1 (de) * | 2013-09-26 | 2015-03-26 | Henkel Ag & Co. Kgaa | Stabilisierte Inhibitor-Proteasevarianten |
JP2019510037A (ja) | 2016-03-31 | 2019-04-11 | ゴジョ・インダストリーズ・インコーポレイテッド | 抗菌ペプチド刺激性洗浄組成物 |
EP3436041B1 (en) | 2016-03-31 | 2023-05-24 | Gojo Industries, Inc. | Sanitizer composition with probiotic/prebiotic active ingredient |
EP3544575A1 (en) | 2016-11-23 | 2019-10-02 | GOJO Industries, Inc. | Sanitizer composition with probiotic/prebiotic active ingredient |
US11446235B2 (en) * | 2017-05-07 | 2022-09-20 | Locus Ip Company, Llc | Cosmetic compositions for skin health and methods of using same |
WO2023225459A2 (en) | 2022-05-14 | 2023-11-23 | Novozymes A/S | Compositions and methods for preventing, treating, supressing and/or eliminating phytopathogenic infestations and infections |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4760025A (en) | 1984-05-29 | 1988-07-26 | Genencor, Inc. | Modified enzymes and methods for making same |
NZ208612A (en) | 1983-06-24 | 1991-09-25 | Genentech Inc | Method of producing "procaryotic carbonyl hydrolases" containing predetermined, site specific mutations |
US5801038A (en) * | 1984-05-29 | 1998-09-01 | Genencor International Inc. | Modified subtilisins having amino acid alterations |
NZ221627A (en) | 1986-09-09 | 1993-04-28 | Genencor Inc | Preparation of enzymes, modifications, catalytic triads to alter ratios or transesterification/hydrolysis ratios |
PT89702B (pt) | 1988-02-11 | 1994-04-29 | Gist Brocades Nv | Processo para a preparacao de novos enzimas proteoliticos e de detergentes que os contem |
DK316989D0 (da) | 1989-06-26 | 1989-06-26 | Novo Nordisk As | Enzymer |
DE69033388T2 (de) | 1989-08-25 | 2000-05-11 | Henkel Research Corp | Alkalisches proteolytisches enzym und verfahren zur herstellung |
US5230891A (en) * | 1990-08-20 | 1993-07-27 | Kanebo Limited | Modified protease, method of producing the same and cosmetic products containing the modified protease |
EP0769549A3 (en) | 1990-12-21 | 1997-05-21 | Novo Nordisk A/S | Enzyme mutants having a low degree of variation of the molecular charge over a pH range |
US5340735A (en) | 1991-05-29 | 1994-08-23 | Cognis, Inc. | Bacillus lentus alkaline protease variants with increased stability |
ES2098731T3 (es) | 1991-06-19 | 1997-05-01 | Exxon Chemical Patents Inc | Metodo para suprimir la formacion de nebulizacion a partir de un aceite lubricante de un solo uso. |
AU682314B2 (en) | 1992-07-17 | 1997-10-02 | Genencor International, Inc. | High alkaline serine proteases |
MA23346A1 (fr) * | 1993-10-14 | 1995-04-01 | Genencor Int | Variantes de la subtilisine |
ES2287931T3 (es) | 1993-10-14 | 2007-12-16 | THE PROCTER & GAMBLE COMPANY | Composiciones limpiadoras que contienen proteasa. |
ES2302330T3 (es) | 1994-02-24 | 2008-07-01 | Henkel Kommanditgesellschaft Auf Aktien | Enzimas mejoradas y detergentes que las contienen. |
US5691295A (en) * | 1995-01-17 | 1997-11-25 | Cognis Gesellschaft Fuer Biotechnologie Mbh | Detergent compositions |
ES2364776T3 (es) * | 1994-02-24 | 2011-09-14 | HENKEL AG & CO. KGAA | Enzimas mejoradas y detergentes que las contienen. |
US6599730B1 (en) * | 1994-05-02 | 2003-07-29 | Procter & Gamble Company | Subtilisin 309 variants having decreased adsorption and increased hydrolysis |
FR2737116B1 (fr) * | 1995-07-25 | 1997-08-22 | Oreal | Composition stable contenant un actif cosmetique et/ou dermatologique sensible a l'eau |
FR2737119B1 (fr) * | 1995-07-25 | 1997-09-12 | Oreal | Composition siliconee contenant un actif sensible a l'eau |
-
1995
- 1995-08-23 DE DE19530816A patent/DE19530816A1/de not_active Withdrawn
-
1996
- 1996-08-14 DK DK96929256T patent/DK0845972T3/da active
- 1996-08-14 DE DE59608385T patent/DE59608385D1/de not_active Expired - Fee Related
- 1996-08-14 WO PCT/EP1996/003589 patent/WO1997007770A1/de active IP Right Grant
- 1996-08-14 EP EP96929256A patent/EP0845972B1/de not_active Revoked
- 1996-08-14 AT AT96929256T patent/ATE209888T1/de not_active IP Right Cessation
- 1996-08-14 JP JP9509779A patent/JPH11512092A/ja active Pending
- 1996-08-14 US US09/011,889 patent/US6509021B1/en not_active Expired - Fee Related
- 1996-08-14 ES ES96929256T patent/ES2169258T3/es not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DK0845972T3 (da) | 2002-04-02 |
EP0845972B1 (de) | 2001-12-05 |
EP0845972A1 (de) | 1998-06-10 |
ATE209888T1 (de) | 2001-12-15 |
JPH11512092A (ja) | 1999-10-19 |
DE19530816A1 (de) | 1997-02-27 |
US6509021B1 (en) | 2003-01-21 |
DE59608385D1 (de) | 2002-01-17 |
WO1997007770A1 (de) | 1997-03-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2169258T3 (es) | Utilizacion de proteasa de subtilisina mutada en productos cosmeticos. | |
ES2190653T3 (es) | Productos de reaccion del acido hialuronico y de aminoacidos naturales y su utilizacion en composiciones cosmeticas y farmaceuticas. | |
AR053946A2 (es) | Variante de alfa-amilasa de bacillus stearothermophilus original | |
ES2168285T3 (es) | Agentes endoparasiticidas que contienen praziquantel y epsiprantel. | |
ES2094669T3 (es) | Composiciones a base de un sistema abrasivo y de un sistema tensioactivo. | |
CO5150154A1 (es) | Composicion de sustrato y metodo para usarlo para el secuestro de irritantes de la piel | |
ES2174248T3 (es) | Composiciones para la eliminacion de una placa dental. | |
ES2135062T3 (es) | Pirazolo y pirrolopiridinas. | |
AR009626A1 (es) | Una composicion dermatologica o cosmetica que comprende una cantidad de esfingomielinasa efectiva para producir un aumento en el nivel de las ceramidas de la piel y de la mucosa. | |
ES2194107T3 (es) | Formulaciones farmaceuticas y dieteticas para la profilaxis y tratamiento de trastornos gastrointestinales. | |
ES2182874T3 (es) | Procedimiento de tratamiento de las uñas. | |
ES2102275T5 (es) | Composicion cosmetica o dermatologica que contiene una mezcla de ceramidas, su utilizacion para hidratar la piel. | |
ES2144239T3 (es) | Derivados de vitamina d con sustituyentes en c-25, procedimiento para su preparacion, productos intermedios y la utilizacion para la preparacion de medicamentos. | |
ES2096018T3 (es) | Goma gelana para geles no quebradizos. | |
DK0764209T3 (da) | Albuminekspression i gær | |
DE69006021D1 (de) | Überdruckventil und kryopumpe die dieses verwendet. | |
ES2182374T3 (es) | Preparaciones cosmeticas acuosas en forma de barra. | |
DE3583460D1 (de) | Haarpflegemittel. | |
BR9815469A (pt) | Inibidores de protease | |
ES2136091T3 (es) | Inhibidores de catepsina g y elastasa para prevenir la degradacion del tejido conectivo. | |
ES2129624T3 (es) | Preparacion de proteinas para la prevencion y terapia de periodontitis y otras patologias bacterianas de la cavidad bucal. | |
ES2170143T3 (es) | Composiciones que comprenden halofantrina en una forma especial. | |
ES2166577T3 (es) | Acidos 6- y 7-aminotetrahidroisoquinolin-carboxilicos sustituidos. | |
ES2032465T3 (es) | Variantes de la hirudina, su utilizacion y su preparacion. | |
ES2140175T3 (es) | Utilizacion de la monoetanolamina para preparar una composicion destinada para determinar los cueros cabelludos sensibles. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
Ref document number: 845972 Country of ref document: ES |