ES2167853T3 - N-aril 2-hidroxi alquilamidas. - Google Patents

N-aril 2-hidroxi alquilamidas.

Info

Publication number
ES2167853T3
ES2167853T3 ES98402503T ES98402503T ES2167853T3 ES 2167853 T3 ES2167853 T3 ES 2167853T3 ES 98402503 T ES98402503 T ES 98402503T ES 98402503 T ES98402503 T ES 98402503T ES 2167853 T3 ES2167853 T3 ES 2167853T3
Authority
ES
Spain
Prior art keywords
halogen
alkyl
optionally substituted
hydroxy
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98402503T
Other languages
English (en)
Inventor
Jean-Baptiste Galey
Odile Destree
Lionel Breton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LOreal SA
Original Assignee
LOreal SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LOreal SA filed Critical LOreal SA
Application granted granted Critical
Publication of ES2167853T3 publication Critical patent/ES2167853T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/62—Compounds containing any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylcarbamates
    • C07C271/64—Y being a hydrogen or a carbon atom, e.g. benzoylcarbamates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/46—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylureas
    • C07C275/48—Y being a hydrogen or a carbon atom
    • C07C275/50—Y being a hydrogen or an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/215—Radicals derived from nitrogen analogues of carbonic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)

Abstract

LA INVENCION SE REFIERE A NUEVOS COMPUESTOS DERIVADOS DE N- ARIL 2 - HIDROXI ALQUILAMIDAS, A SU PROCEDIMIENTO DE SINTESIS, A LAS COMPOSICIONES QUE LOS CONTIENEN ASI COMO A LA UTILIZACION COMO PRINCIPIO ACTIVO, EN UN MEDIO FISIOLOGICAMENTE ACEPTABLE, EN UNA COMPOSICION COSMETICA O PARA LA PREPARACION DE UNA COMPOSICION FARMACEUTICA, DE UNA CANTIDAD EFICAZ DE AL MENOS UNO DE ESTOS COMPUESTOS, DESTINANDOSE ESTE COMPUESTO O ESTAS COMPOSICIONES A INDUCIR Y/O A ESTIMULAR EL CRECIMIENTO DEL CABELLO Y/O DETENER SU CAIDA Y/O TRATAR LA HIPERSEBORREA Y/O EL ACNE.
ES98402503T 1997-11-13 1998-10-08 N-aril 2-hidroxi alquilamidas. Expired - Lifetime ES2167853T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9714241A FR2770842B1 (fr) 1997-11-13 1997-11-13 Nouveaux composes derives de n-aryl 2-hydroxy alkylamides

Publications (1)

Publication Number Publication Date
ES2167853T3 true ES2167853T3 (es) 2002-05-16

Family

ID=9513334

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98402503T Expired - Lifetime ES2167853T3 (es) 1997-11-13 1998-10-08 N-aril 2-hidroxi alquilamidas.

Country Status (8)

Country Link
US (1) US6156899A (es)
EP (1) EP0916652B1 (es)
JP (1) JP3222846B2 (es)
AT (1) ATE207887T1 (es)
CA (1) CA2251003C (es)
DE (1) DE69802249T2 (es)
ES (1) ES2167853T3 (es)
FR (1) FR2770842B1 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1123082T3 (da) * 1998-10-23 2006-06-26 Aventis Pharma Sa Præparater til topisk applikation af antiandrogent aktive forbindelser
EP1132396A4 (en) * 1998-11-13 2002-05-08 Kyowa Hakko Kogyo Kk PHYSIOLOGICALLY ACTIVE PEPTIDES
DE10025553A1 (de) * 2000-05-24 2001-11-29 Merck Patent Gmbh Zusammensetzung, enthaltend mindestens ein Aryloxim und mindestens einen Wirkstoff zur Behandlung von Akne und ihre Verwendung
FR2811550B1 (fr) * 2000-07-11 2003-02-14 Oreal Composition a base de vitamines et de sels mineraux, pour diminuer la chute des cheveux et/ou favoriser la repousse des cheveux
AU2005282624A1 (en) * 2004-09-02 2006-03-16 Shih, Charles C-Y. Methods and compositions for enhancing degradation of nuclear receptor transcription factors and uses thereof
FR2918885B1 (fr) 2007-07-17 2009-08-28 Oreal Utilisation d'extrait de bacterie cultivee sur eau thermale pour diminuer les poches et/ou les cernes perioculaires
JP2010200971A (ja) * 2009-03-03 2010-09-16 Hoyu Co Ltd 異常脱毛予測／推定方法、異常脱毛予防／防止方法及び異常脱毛防止剤評価方法
CA2788907A1 (en) 2010-02-04 2011-08-11 Radius Health, Inc. Selective androgen receptor modulators
MX342898B (es) 2010-05-12 2016-10-18 Radius Health Inc * Regimen terapéutico de la sal de diclorhidrato del (r) -6-(2-(etil (4-2(etilamino) etil) bencil) amino)-4-metoxifenil)-5, 6,7,8-tetrahidronaftaleno-2-ol.
BR112013007685B1 (pt) 2010-09-28 2021-11-09 Radius Pharmaceuticals, Inc Compostos moduladores de receptor andrógeno seletivos, composição farmacêutica compreendendo os referidos compostos, método de identificação de um composto capaz de modular um receptor andrógeno, usos de um composto ou da composição e processo para a preparação de um composto
FR3015282B1 (fr) 2013-12-20 2016-01-22 Oreal Utilisation cosmetique d'une huile essentielle de laserpitium siler l. pour les matieres keratiniques.
DK3122426T3 (da) 2014-03-28 2023-04-03 Univ Duke Behandling af brystcancer ved anvendelse af selektive østrogenreceptormodulatorer
US9421264B2 (en) 2014-03-28 2016-08-23 Duke University Method of treating cancer using selective estrogen receptor modulators
AU2017281038B2 (en) 2016-06-22 2021-09-09 Ellipses Pharma Ltd AR+ breast cancer treatment methods
KR20230109795A (ko) 2017-01-05 2023-07-20 래디어스 파마슈티컬스, 인코포레이티드 Rad1901-2hcl의 다형 형태
SG11202013177WA (en) 2018-07-04 2021-01-28 Radius Pharmaceuticals Inc Polymorphic forms of rad 1901-2hcl

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9214120D0 (en) * 1991-07-25 1992-08-12 Ici Plc Therapeutic amides
JP2000508296A (ja) * 1996-03-06 2000-07-04 ロレアル 髪の成長の刺激または誘発および／または抜毛防止のためのｎ―アリール―２―ヒドロキシアルキルアミドの使用

Also Published As

Publication number Publication date
ATE207887T1 (de) 2001-11-15
FR2770842B1 (fr) 1999-12-17
US6156899A (en) 2000-12-05
CA2251003A1 (fr) 1999-05-13
DE69802249D1 (de) 2001-12-06
EP0916652A1 (fr) 1999-05-19
EP0916652B1 (fr) 2001-10-31
JPH11228525A (ja) 1999-08-24
FR2770842A1 (fr) 1999-05-14
CA2251003C (fr) 2003-10-07
DE69802249T2 (de) 2002-05-02
JP3222846B2 (ja) 2001-10-29

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