NO972942L - 4-amino-2-ureido-pyrimidin-5-karboksylsyreamider, fremgangsmåter for deres fremstilling, legemidler inneholdende disse forbindelsene og deres anvendelse - Google Patents
4-amino-2-ureido-pyrimidin-5-karboksylsyreamider, fremgangsmåter for deres fremstilling, legemidler inneholdende disse forbindelsene og deres anvendelseInfo
- Publication number
- NO972942L NO972942L NO972942A NO972942A NO972942L NO 972942 L NO972942 L NO 972942L NO 972942 A NO972942 A NO 972942A NO 972942 A NO972942 A NO 972942A NO 972942 L NO972942 L NO 972942L
- Authority
- NO
- Norway
- Prior art keywords
- amino
- ureido
- pyrimidine
- compounds
- processes
- Prior art date
Links
- SHGZREYDEWHPDB-UHFFFAOYSA-N 4-amino-2-(carbamoylamino)pyrimidine-5-carboxamide Chemical class NC(=O)NC1=NC=C(C(N)=O)C(N)=N1 SHGZREYDEWHPDB-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- NKTWBSSRNCDNCD-UHFFFAOYSA-N 4-amino-2-(2-oxoimidazolidin-1-yl)pyrimidine-5-carboxamide Chemical class N1=C(N)C(C(=O)N)=CN=C1N1C(=O)NCC1 NKTWBSSRNCDNCD-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000000876 trifluoromethoxy group Chemical group FC(F)(F)O* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19625088A DE19625088A1 (de) | 1996-06-24 | 1996-06-24 | 4-Amino-2-ureido-pyrimidin-5-carbonsäureamide, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO972942D0 NO972942D0 (no) | 1997-06-23 |
| NO972942L true NO972942L (no) | 1997-12-29 |
| NO312133B1 NO312133B1 (no) | 2002-03-25 |
Family
ID=7797761
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19972942A NO312133B1 (no) | 1996-06-24 | 1997-06-23 | 4-amino-2-ureido-pyrimidin-5-karboksylsyreamider, fremgangsmåter for deres fremstilling, legemidler inneholdendedisse forbindelsene og deres anvendelse |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5773447A (no) |
| EP (1) | EP0816359B1 (no) |
| JP (1) | JP4101905B2 (no) |
| AT (1) | ATE281453T1 (no) |
| CA (1) | CA2208611C (no) |
| DE (2) | DE19625088A1 (no) |
| DK (1) | DK0816359T3 (no) |
| ES (1) | ES2230576T3 (no) |
| MX (1) | MX9704621A (no) |
| NO (1) | NO312133B1 (no) |
| PT (1) | PT816359E (no) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19625089A1 (de) * | 1996-06-24 | 1998-01-02 | Hoechst Ag | 4-Amino-2-ureido-pyrimidin-5-carbonsäureamide, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
| DE60025243T2 (de) * | 1999-10-12 | 2006-06-22 | Takeda Pharmaceutical Co. Ltd. | Pyrimidin-5-carboximidverbindungen, verfahren zur herstellung derselben und deren verwendung |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2853220A1 (de) * | 1978-12-09 | 1980-07-03 | Hoechst Ag | Neue amino-pyrimidin-carbanilide, verfahren zu ihrer herstellung, diese verbindungen enthaltende arzneimittel und ihre verwendung |
| DE3522940A1 (de) * | 1985-06-27 | 1987-01-08 | Hoechst Ag | 4-amino-2-(imidazolidin-2-on-1-yl)-pyrimidin-5-carbonsaeure-(n-(3-trifluormethyl-phenyl)-amide) zur antithrombotischen prophylaxe und behandlung sowie ihre verwendung zur herstellung von antithrombotisch wirksamen arzneimitteln |
| DE59305012D1 (de) * | 1992-02-22 | 1997-02-20 | Hoechst Ag | 4-Amino-2-ureido-pyrimidin-5-carbonsäureamide, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
| ATE158581T1 (de) * | 1992-02-22 | 1997-10-15 | Hoechst Ag | Lösliche salze von 4-amino-2-(4,4-dimethyl- imidazolidin-2-on-1-yl)-pyrimidin-5 -carbonsäure- n-methyl-n-(3-trifluormethyl-phenyl)- amid, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel und ausgangsprodukte |
| DE19625089A1 (de) * | 1996-06-24 | 1998-01-02 | Hoechst Ag | 4-Amino-2-ureido-pyrimidin-5-carbonsäureamide, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
-
1996
- 1996-06-24 DE DE19625088A patent/DE19625088A1/de not_active Withdrawn
-
1997
- 1997-06-12 EP EP97109548A patent/EP0816359B1/de not_active Expired - Lifetime
- 1997-06-12 AT AT97109548T patent/ATE281453T1/de active
- 1997-06-12 PT PT97109548T patent/PT816359E/pt unknown
- 1997-06-12 DK DK97109548T patent/DK0816359T3/da active
- 1997-06-12 ES ES97109548T patent/ES2230576T3/es not_active Expired - Lifetime
- 1997-06-12 DE DE59712054T patent/DE59712054D1/de not_active Expired - Lifetime
- 1997-06-13 US US08/874,255 patent/US5773447A/en not_active Expired - Lifetime
- 1997-06-20 MX MX9704621A patent/MX9704621A/es not_active IP Right Cessation
- 1997-06-23 NO NO19972942A patent/NO312133B1/no not_active IP Right Cessation
- 1997-06-23 JP JP16581497A patent/JP4101905B2/ja not_active Expired - Fee Related
- 1997-06-23 CA CA002208611A patent/CA2208611C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ATE281453T1 (de) | 2004-11-15 |
| US5773447A (en) | 1998-06-30 |
| DE59712054D1 (de) | 2004-12-09 |
| JP4101905B2 (ja) | 2008-06-18 |
| CA2208611C (en) | 2006-10-03 |
| NO312133B1 (no) | 2002-03-25 |
| MX9704621A (es) | 1997-12-31 |
| PT816359E (pt) | 2005-02-28 |
| EP0816359B1 (de) | 2004-11-03 |
| DE19625088A1 (de) | 1998-01-02 |
| EP0816359A1 (de) | 1998-01-07 |
| JPH1072462A (ja) | 1998-03-17 |
| DK0816359T3 (da) | 2005-03-14 |
| NO972942D0 (no) | 1997-06-23 |
| ES2230576T3 (es) | 2005-05-01 |
| CA2208611A1 (en) | 1997-12-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |