ES2166987T3 - Metodo de formar articulos y superficies modeladas mediante micromoldeo capilar. - Google Patents
Metodo de formar articulos y superficies modeladas mediante micromoldeo capilar.Info
- Publication number
- ES2166987T3 ES2166987T3 ES97915950T ES97915950T ES2166987T3 ES 2166987 T3 ES2166987 T3 ES 2166987T3 ES 97915950 T ES97915950 T ES 97915950T ES 97915950 T ES97915950 T ES 97915950T ES 2166987 T3 ES2166987 T3 ES 2166987T3
- Authority
- ES
- Spain
- Prior art keywords
- substrate surface
- chemically
- biochemically active
- fluid
- pattern
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B81—MICROSTRUCTURAL TECHNOLOGY
- B81C—PROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICROSTRUCTURAL DEVICES OR SYSTEMS
- B81C1/00—Manufacture or treatment of devices or systems in or on a substrate
- B81C1/00015—Manufacture or treatment of devices or systems in or on a substrate for manufacturing microsystems
- B81C1/00206—Processes for functionalising a surface, e.g. provide the surface with specific mechanical, chemical or biological properties
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6957—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a device or a kit, e.g. stents or microdevices
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C31/00—Handling, e.g. feeding of the material to be shaped, storage of plastics material before moulding; Automation, i.e. automated handling lines in plastics processing plants, e.g. using manipulators or robots
- B29C31/04—Feeding of the material to be moulded, e.g. into a mould cavity
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C37/00—Component parts, details, accessories or auxiliary operations, not covered by group B29C33/00 or B29C35/00
- B29C37/0053—Moulding articles characterised by the shape of the surface, e.g. ribs, high polish
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C39/00—Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor
- B29C39/22—Component parts, details or accessories; Auxiliary operations
- B29C39/24—Feeding the material into the mould
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C67/00—Shaping techniques not covered by groups B29C39/00 - B29C65/00, B29C70/00 or B29C73/00
- B29C67/24—Shaping techniques not covered by groups B29C39/00 - B29C65/00, B29C70/00 or B29C73/00 characterised by the choice of material
- B29C67/246—Moulding high reactive monomers or prepolymers, e.g. by reaction injection moulding [RIM], liquid injection moulding [LIM]
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/00382—Stamping
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/00414—Means for dispensing and evacuation of reagents using suction
- B01J2219/00416—Vacuum
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/00427—Means for dispensing and evacuation of reagents using masks
- B01J2219/0043—Means for dispensing and evacuation of reagents using masks for direct application of reagents, e.g. through openings in a shutter
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00457—Dispensing or evacuation of the solid phase support
- B01J2219/00459—Beads
- B01J2219/00466—Beads in a slurry
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00612—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports the surface being inorganic
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00614—Delimitation of the attachment areas
- B01J2219/00621—Delimitation of the attachment areas by physical means, e.g. trenches, raised areas
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00623—Immobilisation or binding
- B01J2219/0063—Other, e.g. van der Waals forces, hydrogen bonding
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00632—Introduction of reactive groups to the surface
- B01J2219/00637—Introduction of reactive groups to the surface by coating it with another layer
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00646—Making arrays on substantially continuous surfaces the compounds being bound to beads immobilised on the solid supports
- B01J2219/00648—Making arrays on substantially continuous surfaces the compounds being bound to beads immobilised on the solid supports by the use of solid beads
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00659—Two-dimensional arrays
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00709—Type of synthesis
- B01J2219/00713—Electrochemical synthesis
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C33/00—Moulds or cores; Details thereof or accessories therefor
- B29C33/42—Moulds or cores; Details thereof or accessories therefor characterised by the shape of the moulding surface, e.g. ribs or grooves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2105/00—Condition, form or state of moulded material or of the material to be shaped
- B29K2105/0002—Condition, form or state of moulded material or of the material to be shaped monomers or prepolymers
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B81—MICROSTRUCTURAL TECHNOLOGY
- B81B—MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
- B81B2201/00—Specific applications of microelectromechanical systems
- B81B2201/02—Sensors
- B81B2201/0214—Biosensors; Chemical sensors
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B81—MICROSTRUCTURAL TECHNOLOGY
- B81C—PROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICROSTRUCTURAL DEVICES OR SYSTEMS
- B81C2201/00—Manufacture or treatment of microstructural devices or systems
- B81C2201/03—Processes for manufacturing substrate-free structures
- B81C2201/034—Moulding
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- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
- C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
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- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05K—PRINTED CIRCUITS; CASINGS OR CONSTRUCTIONAL DETAILS OF ELECTRIC APPARATUS; MANUFACTURE OF ASSEMBLAGES OF ELECTRICAL COMPONENTS
- H05K3/00—Apparatus or processes for manufacturing printed circuits
- H05K3/0073—Masks not provided for in groups H05K3/02 - H05K3/46, e.g. for photomechanical production of patterned surfaces
- H05K3/0079—Masks not provided for in groups H05K3/02 - H05K3/46, e.g. for photomechanical production of patterned surfaces characterised by the method of application or removal of the mask
-
- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05K—PRINTED CIRCUITS; CASINGS OR CONSTRUCTIONAL DETAILS OF ELECTRIC APPARATUS; MANUFACTURE OF ASSEMBLAGES OF ELECTRICAL COMPONENTS
- H05K3/00—Apparatus or processes for manufacturing printed circuits
- H05K3/02—Apparatus or processes for manufacturing printed circuits in which the conductive material is applied to the surface of the insulating support and is thereafter removed from such areas of the surface which are not intended for current conducting or shielding
- H05K3/06—Apparatus or processes for manufacturing printed circuits in which the conductive material is applied to the surface of the insulating support and is thereafter removed from such areas of the surface which are not intended for current conducting or shielding the conductive material being removed chemically or electrolytically, e.g. by photo-etch process
- H05K3/061—Etching masks
Landscapes
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Mechanical Engineering (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nanotechnology (AREA)
- Manufacturing & Machinery (AREA)
- Organic Chemistry (AREA)
- Materials Engineering (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Robotics (AREA)
- Physics & Mathematics (AREA)
- Composite Materials (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- General Physics & Mathematics (AREA)
- Microelectronics & Electronic Packaging (AREA)
- Crystallography & Structural Chemistry (AREA)
- Molecular Biology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Moulds For Moulding Plastics Or The Like (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Bipolar Transistors (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Chemically Coating (AREA)
Abstract
LA INVENCION SE REFIERE A TECNICAS PARA ADORNAR GRAFICAMENTE AGENTES QUIMICA O BIOQUIMICAMENTE ACTIVOS SOBRE UNA SUPERFICIE DE SUSTRATO QUE IMPLICA EL EMPLEO DE UN MICROMOLDE QUE TIENE UNA SUPERFICIE DE CONTORNO QUE INCLUYE DIENTES QUE DEFINEN UN DIBUJO Y QUE FORMAN, SOBRE UNA SUPERFICIE DE SUSTRATO, UN AGENTE QUIMICA O BIOQUIMICAMENTE ACTIVO O UN PRECURSOR DE UNA ESTRUCTURA SOBRE LA SUPERFICIE. UN AGENTE QUIMICA O BIOQUIMICAMENTE ACTIVO O PRECURSOR DE FLUIDO TAMBIEN PUEDE SER TRANSFERIDO DESDE LOS DIENTES EN UN APLICADOR A UNA SUPERFICIE DE SUSTRATO. LA SUPERFICIE DE SUSTRATO PUEDE SER PLANA O NO PLANA. SE PUEDEN EMPLEAR PRECURSORES FLUIDOS DE ESTRUCTURAS POLIMERICAS, CERAMICAS INORGANICAS Y SALES, Y SIMILARES PARA FORMAR ARTICULOS POLIMERICOS, SALES INORGANICAS Y CERAMICAS, ETC ADORNADOS GRAFICAMENTE EN LA SUPERFICIE. LOS ARTICULOS, DE ACUERDO CON UN ASPECTO, ESTAN FORMADOS EN UN PATRON QUE INCLUYE UNA PORCION QUE TIENE UNA DIMENSION LATERAL INFERIOR A APROXIMADAMENTE 1 MILIMETRO. SE PUEDEN LLEVAR A CABO DIMENSIONES INFERIORES. EL PATRON DE DIENTES DEL APLICADOR PUEDE USARSE PARA TRANSFERIR SEPARADAMENTE DISTINTOS AGENTES QUIMICA Y BIOQUIMICAMENTE ACTIVOS O PRECURSORES FLUIDOS PARA SEPARAR,REGIONES AISLADAS DE UNA SUPERFICIE DE SUSTRATO. LA INVENCION SE REFIERE A LA SINTESIS SENCILLA Y DE BAJO COSTO DE UNA BIBLIOTECA QUIMICA O BIOQUIMICA COMBINATORIA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US61692996A | 1996-03-15 | 1996-03-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2166987T3 true ES2166987T3 (es) | 2002-05-01 |
Family
ID=24471572
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES97915950T Expired - Lifetime ES2166987T3 (es) | 1996-03-15 | 1997-03-14 | Metodo de formar articulos y superficies modeladas mediante micromoldeo capilar. |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0894043B1 (es) |
AT (1) | ATE207798T1 (es) |
AU (1) | AU723909B2 (es) |
CA (1) | CA2248576C (es) |
DE (1) | DE69707853T2 (es) |
ES (1) | ES2166987T3 (es) |
WO (1) | WO1997033737A1 (es) |
Families Citing this family (60)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5776748A (en) | 1993-10-04 | 1998-07-07 | President And Fellows Of Harvard College | Method of formation of microstamped patterns on plates for adhesion of cells and other biological materials, devices and uses therefor |
US6355198B1 (en) | 1996-03-15 | 2002-03-12 | President And Fellows Of Harvard College | Method of forming articles including waveguides via capillary micromolding and microtransfer molding |
WO1998008931A1 (en) | 1996-08-26 | 1998-03-05 | Princeton University | Reversibly sealable microstructure sorting devices |
DE19706570C1 (de) | 1997-02-19 | 1998-02-26 | Inst Physikalische Hochtech Ev | Verfahren zur Herstellung von strukturierten, selbstorganisierten molekularen Monolagen einzelner molekularer Spezies, insbesondere von Substanzbibliotheken |
AU6704398A (en) * | 1997-03-19 | 1998-10-12 | Biosepra Inc. | Multifunctional ceramic particles as solid supports for solid phase and com binatorial solid phase synthesis |
GB9801061D0 (en) | 1998-01-20 | 1998-03-18 | Univ Nottingham | Patterning technique |
US6033202A (en) * | 1998-03-27 | 2000-03-07 | Lucent Technologies Inc. | Mold for non - photolithographic fabrication of microstructures |
US7282240B1 (en) | 1998-04-21 | 2007-10-16 | President And Fellows Of Harvard College | Elastomeric mask and use in fabrication of devices |
DE19827754C1 (de) * | 1998-06-23 | 2000-02-10 | Graffinity Pharm Design Gmbh | Einrichtung für eine nahezu gleichzeitige Synthese einer Vielzahl von Proben |
DE59906190D1 (de) * | 1998-04-30 | 2003-08-07 | Graffinity Pharmaceuticals Ag | Vorrichtung für den transport von flüssigkeiten entlang vorgegebener leitwege |
JP3780700B2 (ja) * | 1998-05-26 | 2006-05-31 | セイコーエプソン株式会社 | パターン形成方法、パターン形成装置、パターン形成用版、パターン形成用版の製造方法、カラーフィルタの製造方法、導電膜の製造方法及び液晶パネルの製造方法 |
US6284197B1 (en) * | 1998-06-05 | 2001-09-04 | The Regents Of The University Of California | Optical amplification of molecular interactions using liquid crystals |
US6858423B1 (en) | 1998-06-05 | 2005-02-22 | The Regents Of The University Of California | Optical Amplification of molecular interactions using liquid crystals |
US6576478B1 (en) | 1998-07-14 | 2003-06-10 | Zyomyx, Inc. | Microdevices for high-throughput screening of biomolecules |
US6897073B2 (en) | 1998-07-14 | 2005-05-24 | Zyomyx, Inc. | Non-specific binding resistant protein arrays and methods for making the same |
US6682942B1 (en) | 1998-07-14 | 2004-01-27 | Zyomyx, Inc. | Microdevices for screening biomolecules |
US6406921B1 (en) | 1998-07-14 | 2002-06-18 | Zyomyx, Incorporated | Protein arrays for high-throughput screening |
US6429027B1 (en) | 1998-12-28 | 2002-08-06 | Illumina, Inc. | Composite arrays utilizing microspheres |
US7582420B2 (en) | 2001-07-12 | 2009-09-01 | Illumina, Inc. | Multiplex nucleic acid reactions |
US6686184B1 (en) * | 2000-05-25 | 2004-02-03 | President And Fellows Of Harvard College | Patterning of surfaces utilizing microfluidic stamps including three-dimensionally arrayed channel networks |
US6645432B1 (en) | 2000-05-25 | 2003-11-11 | President & Fellows Of Harvard College | Microfluidic systems including three-dimensionally arrayed channel networks |
US7323143B2 (en) | 2000-05-25 | 2008-01-29 | President And Fellows Of Harvard College | Microfluidic systems including three-dimensionally arrayed channel networks |
GB0013394D0 (en) * | 2000-06-01 | 2000-07-26 | Microemissive Displays Ltd | A method of creating a color optoelectronic device |
EP1314189B1 (en) | 2000-08-22 | 2013-02-27 | President and Fellows of Harvard College | Electrical device comprising doped semiconductor nanowires and method for its production |
US6653089B2 (en) | 2000-09-18 | 2003-11-25 | President And Fellows Of Harvard College | Differential treatment of selected parts of a single cell with different fluid components |
JP3922338B2 (ja) | 2000-09-20 | 2007-05-30 | セイコーエプソン株式会社 | 基板の製造方法及び製造装置 |
EP1736760A3 (en) | 2000-12-11 | 2008-06-18 | President And Fellows Of Harvard College | Nanosensors |
KR20080005303A (ko) | 2000-12-11 | 2008-01-10 | 프레지던트 앤드 펠로우즈 오브 하버드 칼리지 | 나노센서 |
US7094810B2 (en) | 2001-06-08 | 2006-08-22 | Labopharm, Inc. | pH-sensitive block copolymers for pharmaceutical compositions |
US6939564B2 (en) | 2001-06-08 | 2005-09-06 | Labopharm, Inc. | Water-soluble stabilized self-assembled polyelectrolytes |
US7517496B2 (en) | 2001-07-17 | 2009-04-14 | Bio-Rad Laboratories, Inc. | Latex based adsorbent chip |
EP1483794A4 (en) * | 2001-07-17 | 2006-05-03 | Ciphergen Biosystems Inc | ADSORBENT CHIP BASED ON LATEX |
US20030099949A1 (en) * | 2001-10-05 | 2003-05-29 | Surmodics, Inc. | Arrays having clustered arrangements and methods of making and using |
DE10217089A1 (de) * | 2002-04-17 | 2003-10-30 | Inst Neue Mat Gemein Gmbh | Transferverfahren zur Herstellung mikrostrukturierter Substrate |
DE10217151A1 (de) * | 2002-04-17 | 2003-10-30 | Clariant Gmbh | Nanoimprint-Resist |
US7442336B2 (en) * | 2003-08-21 | 2008-10-28 | Molecular Imprints, Inc. | Capillary imprinting technique |
WO2005080983A2 (en) | 2003-09-23 | 2005-09-01 | Wisconsin Alumni Research Foundation | Using liquid crystals to detect affinity microcontact printed biomolecules |
US7795007B2 (en) | 2003-09-23 | 2010-09-14 | Wisconsin Alumni Research Foundation | Detection of post-translationally modified peptides with liquid crystals |
FR2861178B1 (fr) * | 2003-10-20 | 2006-05-19 | Univ Claude Bernard Lyon | Microplaques en elastomere porteuses de ligands reactifs, ainsi que leur procede de preparation |
DE102004020173B4 (de) * | 2004-04-24 | 2014-02-20 | Robert Bosch Gmbh | Mikrostrukturiertes Bauelement und ein Verfahren zum Herstellen eines mikrostrukturierten Bauelements |
DE102004056980A1 (de) | 2004-11-25 | 2006-06-01 | Clondiag Chip Technologies Gmbh | Verfahren zur ortsspezifischen Synthese von Biopolymeren auf festen Trägern |
EP1831973A2 (en) | 2004-12-06 | 2007-09-12 | The President and Fellows of Harvard College | Nanoscale wire-based data storage |
CN101248709A (zh) | 2005-05-18 | 2008-08-20 | 哈佛大学 | 微流体网络中传导通路、微电路和微结构的制造 |
JP4595119B2 (ja) * | 2005-05-23 | 2010-12-08 | 独立行政法人物質・材料研究機構 | 微細構造パターニング方法 |
US20100227382A1 (en) | 2005-05-25 | 2010-09-09 | President And Fellows Of Harvard College | Nanoscale sensors |
WO2006132659A2 (en) | 2005-06-06 | 2006-12-14 | President And Fellows Of Harvard College | Nanowire heterostructures |
US20100160182A1 (en) * | 2005-06-13 | 2010-06-24 | Northwestern University | Metal Ion-Based Immobilization |
US20070110639A1 (en) * | 2005-10-14 | 2007-05-17 | Pennsylvania State University | System and method for positioning and synthesizing of nanostructures |
CA2655340C (en) | 2006-06-12 | 2016-10-25 | President And Fellows Of Harvard College | Nanosensors and related technologies |
WO2008033303A2 (en) | 2006-09-11 | 2008-03-20 | President And Fellows Of Harvard College | Branched nanoscale wires |
EP2095100B1 (en) | 2006-11-22 | 2016-09-21 | President and Fellows of Harvard College | Method of operating a nanowire field effect transistor sensor |
EP3075867B1 (en) | 2008-09-03 | 2019-03-13 | Quantumdx Group Limited | Sensing strategies and methods for nucleic acid detection using biosensors |
WO2010026490A1 (en) | 2008-09-03 | 2010-03-11 | Quantumdx Group Limited | Design, synthesis and use of synthetic nucleotides comprising charge mass tags |
US20120135158A1 (en) | 2009-05-26 | 2012-05-31 | Sharp Kabushiki Kaisha | Methods and systems for electric field deposition of nanowires and other devices |
WO2011038228A1 (en) | 2009-09-24 | 2011-03-31 | President And Fellows Of Harvard College | Bent nanowires and related probing of species |
US9073033B2 (en) | 2010-01-19 | 2015-07-07 | Illumina, Inc. | Methods and compositions for processing chemical reactions |
KR101636453B1 (ko) * | 2015-01-29 | 2016-07-05 | 한림대학교 산학협력단 | 유기 박막 트랜지스터 및 그 제조 방법 |
WO2016137722A1 (en) * | 2015-02-24 | 2016-09-01 | 3M Innovative Properties Company | 3-d printing surface |
DE102019209700A1 (de) * | 2019-07-02 | 2021-01-07 | Hahn-Schickard-Gesellschaft für angewandte Forschung e.V. | Verfahren zum herstellen eines formwerkzeugs und formwerkzeug zum herstellen eines optischen elements |
DE102020204766A1 (de) | 2020-04-15 | 2021-10-21 | Robert Bosch Gesellschaft mit beschränkter Haftung | Verfahren zur Herstellung von Dämpferstrukturen an einem mikromechanischen Wafer |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4258001A (en) * | 1978-12-27 | 1981-03-24 | Eastman Kodak Company | Element, structure and method for the analysis or transport of liquids |
WO1984002578A1 (en) * | 1982-12-21 | 1984-07-05 | Comtech Res Unit | Assay technique |
US4555414A (en) * | 1983-04-15 | 1985-11-26 | Polyonics Corporation | Process for producing composite product having patterned metal layer |
US5227474A (en) * | 1987-02-13 | 1993-07-13 | Abbott Laboratories | Bifunctional chelating agents |
GB9003079D0 (en) * | 1990-02-12 | 1990-04-11 | Alcan Int Ltd | Lithographic plates |
US5439829A (en) * | 1991-01-30 | 1995-08-08 | Eli Lilly And Company | Immobilization of biologically active molecules by changing the Oxidation state of a chelated transition metal ion |
US5385116A (en) * | 1992-03-24 | 1995-01-31 | Sumitomo Electric Industries, Ltd. | Method for producing organic crystal film |
US5512131A (en) * | 1993-10-04 | 1996-04-30 | President And Fellows Of Harvard College | Formation of microstamped patterns on surfaces and derivative articles |
JP3239598B2 (ja) * | 1994-02-25 | 2001-12-17 | キヤノン株式会社 | 回折光学素子の製造方法 |
ES2133166T3 (es) * | 1994-03-14 | 1999-09-01 | Studiengesellschaft Kohle Mbh | Reduccion electroquimica de sales metalicas como metodo de preparar coloides metalicos altamente y agrupaciones de metales fijados a sustratos por reduccion electroquimica de sales metalicas. |
US5620850A (en) * | 1994-09-26 | 1997-04-15 | President And Fellows Of Harvard College | Molecular recognition at surfaces derivatized with self-assembled monolayers |
EP0812434B1 (en) * | 1995-03-01 | 2013-09-18 | President and Fellows of Harvard College | Microcontact printing on surfaces and derivative articles |
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- 1997-03-14 AU AU23247/97A patent/AU723909B2/en not_active Ceased
- 1997-03-14 ES ES97915950T patent/ES2166987T3/es not_active Expired - Lifetime
- 1997-03-14 WO PCT/US1997/004005 patent/WO1997033737A1/en active IP Right Grant
- 1997-03-14 AT AT97915950T patent/ATE207798T1/de not_active IP Right Cessation
- 1997-03-14 CA CA002248576A patent/CA2248576C/en not_active Expired - Fee Related
- 1997-03-14 EP EP97915950A patent/EP0894043B1/en not_active Expired - Lifetime
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AU723909B2 (en) | 2000-09-07 |
AU2324797A (en) | 1997-10-01 |
EP0894043A1 (en) | 1999-02-03 |
CA2248576A1 (en) | 1997-09-18 |
CA2248576C (en) | 2006-01-24 |
ATE207798T1 (de) | 2001-11-15 |
DE69707853D1 (de) | 2001-12-06 |
DE69707853T2 (de) | 2002-06-27 |
EP0894043B1 (en) | 2001-10-31 |
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