ES2160722T3 - Composiciones conservadas de farmacos oftalmicos que contienen compuestos polimeros de amonio cuaternario. - Google Patents

Composiciones conservadas de farmacos oftalmicos que contienen compuestos polimeros de amonio cuaternario.

Info

Publication number
ES2160722T3
ES2160722T3 ES95939996T ES95939996T ES2160722T3 ES 2160722 T3 ES2160722 T3 ES 2160722T3 ES 95939996 T ES95939996 T ES 95939996T ES 95939996 T ES95939996 T ES 95939996T ES 2160722 T3 ES2160722 T3 ES 2160722T3
Authority
ES
Spain
Prior art keywords
quaternary ammonium
conserved
compositions
containing polymer
polymer compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95939996T
Other languages
English (en)
Inventor
Suketu Dipakbhai Desai
Diane S Nelms
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alcon Vision LLC
Original Assignee
Alcon Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Laboratories Inc filed Critical Alcon Laboratories Inc
Application granted granted Critical
Publication of ES2160722T3 publication Critical patent/ES2160722T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

SE PRESENTAN COMPOSICIONES OFTALMOLOGICAS CONSERVADAS ESTABLES AL ALMACENAMIENTO QUE CONTIENEN DROGAS ACIDICAS EN COMBINACION CON COMPUESTOS POLIMERICOS DE AMONIO CUATERNARIO Y ACIDO BORICO.
ES95939996T 1994-11-16 1995-11-16 Composiciones conservadas de farmacos oftalmicos que contienen compuestos polimeros de amonio cuaternario. Expired - Lifetime ES2160722T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/340,763 US5603929A (en) 1994-11-16 1994-11-16 Preserved ophthalmic drug compositions containing polymeric quaternary ammonium compounds

Publications (1)

Publication Number Publication Date
ES2160722T3 true ES2160722T3 (es) 2001-11-16

Family

ID=23334841

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95939996T Expired - Lifetime ES2160722T3 (es) 1994-11-16 1995-11-16 Composiciones conservadas de farmacos oftalmicos que contienen compuestos polimeros de amonio cuaternario.

Country Status (13)

Country Link
US (2) US5603929A (es)
EP (1) EP0739197B1 (es)
JP (1) JP2954356B2 (es)
AT (1) ATE203897T1 (es)
AU (1) AU686917B2 (es)
CA (1) CA2180554C (es)
DE (1) DE69522094T2 (es)
DK (1) DK0739197T3 (es)
ES (1) ES2160722T3 (es)
GR (1) GR3036622T3 (es)
HK (1) HK1012556A1 (es)
PT (1) PT739197E (es)
WO (1) WO1996014829A1 (es)

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AU712908B2 (en) * 1996-02-14 1999-11-18 Alcon Laboratories, Inc. Polymeric quaternary ammonium compounds and their use as ophthalmic antimicrobials
ATE252369T1 (de) * 1996-08-09 2003-11-15 Alcon Mfg Ltd Konservierungssysteme fur cyclodextrine enthaltende arzneimittel
ES2262603T3 (es) 1996-12-13 2006-12-01 Alcon Laboratories, Inc. Composiciones oftalmicas que comprenden aminoalcoholes.
CN100408100C (zh) 1997-07-29 2008-08-06 阿尔康实验室公司 含半乳甘露聚糖聚合物和硼酸盐的眼用组合物
ATE504644T1 (de) 1997-11-26 2011-04-15 Abbott Medical Optics Inc Verwendung von hydroxypropylmethylcellulose in einem reinigungsmittel für kontaktlinsen
US6063745A (en) 1997-11-26 2000-05-16 Allergan Mutli-purpose contact lens care compositions
JPH11249087A (ja) * 1997-12-18 1999-09-17 Tome:Kk コンタクトレンズ用液剤
JP2006111636A (ja) * 1997-12-26 2006-04-27 Astellas Pharma Inc 徐放性医薬組成物
US7678836B2 (en) * 1999-11-04 2010-03-16 Fxs Ventures, Llc Method for rendering a contact lens wettable
CA2395866C (en) * 2000-01-25 2009-10-13 Alcon, Inc. Ophthalmic anti-allergy compositions suitable for use with contact lenses
AR035509A1 (es) * 2000-12-21 2004-06-02 Alcon Inc Solucion de lagrimas artificiales mejorada que contiene una combinacion de tres emolientes y el uso de dicha solucion para la fabricacion de un medicamento
US7923469B2 (en) * 2001-04-30 2011-04-12 Allergen, Inc. Compositions including vitamin-based surfactants and methods for using same
JP4286480B2 (ja) * 2001-09-17 2009-07-01 株式会社メニコン 殺菌液
ATE393627T1 (de) 2003-01-21 2008-05-15 Senju Pharma Co Wässrige flüssige zubereitung mit 2-amino-3-(4- bromobenzoyl)phenylessigsäure
CA2505836C (en) * 2004-05-06 2013-08-27 Alcon Inc. Topical brimonidine tartrate formulations that lack chlorine dioxide
US20060073184A1 (en) * 2004-09-29 2006-04-06 Bausch & Lomb Inc. Viscoelastic composition, methods of use and packaging device with anti-oxidant
KR101312740B1 (ko) * 2004-11-05 2013-09-27 센주 세이야꾸 가부시키가이샤 안구 내 이행성 촉진 수성 점안제
JP5108234B2 (ja) * 2005-02-07 2012-12-26 日本特殊陶業株式会社 マイクロヒータ及びセンサ
US7947010B2 (en) 2005-07-08 2011-05-24 Depuy Products, Inc. Composition and system for wound decontamination
US20100130580A1 (en) * 2006-01-25 2010-05-27 Aciex Therapeutics, Inc. Formulations and Methods for Treating Dry Eye
CA2621616A1 (en) * 2007-02-19 2008-08-19 Alcon Research, Ltd. Topical gatifloxacin formulations
US7705112B2 (en) * 2007-04-17 2010-04-27 Abbott Medical Optics Inc. Polyquaternium-1 synthesis methods
WO2008153746A1 (en) * 2007-05-24 2008-12-18 Aciex Therapeutics, Inc. Formulations and methods for treating dry eye
EP2197461B1 (en) 2007-10-08 2018-02-21 Aurinia Pharmaceuticals Inc. Ophthalmic compositions comprising calcineurin inhibitors or mtor inhibitors
EP2247289A4 (en) * 2008-02-21 2011-05-04 Ista Pharmaceuticals OPHTHALMIC NSAIDS AS ADJUVANTIES
US9192571B2 (en) 2008-03-03 2015-11-24 Allergan, Inc. Ketorolac tromethamine compositions for treating or preventing ocular pain
WO2009117242A2 (en) 2008-03-17 2009-09-24 Alcon Research, Ltd. Aqueous pharmaceutical compositions containing borate-polyol complexes
TWI544927B (zh) 2008-03-17 2016-08-11 愛爾康研究有限公司 具有低濃度的表面活性劑以促進治療劑之生物可利用性的藥學組成物
TWI454289B (zh) * 2008-04-03 2014-10-01 Alcon Res Ltd 使用順式二醇的聚合物於抑制陽離子殺生物劑被吸收進入水凝膠生物材質中之用途
TW201038295A (en) 2009-04-17 2010-11-01 Alcon Res Ltd Aqueous ophthalmic compositions containing anionic therapeutic agents
ES2537385T3 (es) 2009-06-09 2015-06-08 Aurinia Pharmaceuticals Inc. Sistemas de suministro tópico para uso oftálmico
TWI489997B (zh) 2009-06-19 2015-07-01 Alcon Res Ltd 含有硼酸－多元醇錯合物之水性藥學組成物
CN103379904A (zh) 2011-01-18 2013-10-30 千寿制药株式会社 具有保存效能的溴芬酸水性液剂组合物
CN104812370B (zh) * 2012-11-19 2018-05-08 博士伦公司 包含2-氨基-3-(4-溴苯甲酰基)苯基乙酸的含水液体组合物
US20160143869A1 (en) 2013-06-19 2016-05-26 Sentiss Research Center Stable bromfenac solution
WO2015026548A1 (en) 2013-08-20 2015-02-26 3M Innovative Properties Company Boron-silane polyether complex
WO2015087267A2 (en) 2013-12-12 2015-06-18 Sentiss Pharma Private Limited Stable bromfenac ophthalmic solution
US10632202B2 (en) 2016-03-04 2020-04-28 Johnson & Johnson Consumer Inc. Preservative containing compositions
US20190224275A1 (en) 2017-05-12 2019-07-25 Aurinia Pharmaceuticals Inc. Protocol for treatment of lupus nephritis
US20230159202A1 (en) * 2021-11-23 2023-05-25 Bausch + Lomb Ireland Limited Method for making a preservative-free packaged ophthalmic device product

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US4027020A (en) * 1974-10-29 1977-05-31 Millmaster Onyx Corporation Randomly terminated capped polymers
US3931319A (en) * 1974-10-29 1976-01-06 Millmaster Onyx Corporation Capped polymers
US4136173A (en) * 1977-01-31 1979-01-23 American Home Products Corp. Mixed xanthan gum and locust beam gum therapeutic compositions
US4136178A (en) * 1977-01-31 1979-01-23 American Home Products Corp. Locust bean gum therapeutic compositions
US4136177A (en) * 1977-01-31 1979-01-23 American Home Products Corp. Xanthan gum therapeutic compositions
FR2508440B1 (fr) * 1981-06-25 1985-11-08 Saint Gobain Isover Procede de preparation d'alcools orthohydroxybenzyliques
US4407791A (en) * 1981-09-28 1983-10-04 Alcon Laboratories, Inc. Ophthalmic solutions
US4525346A (en) * 1981-09-28 1985-06-25 Alcon Laboratories, Inc. Aqueous antimicrobial ophthalmic solutions
US4836986A (en) * 1984-09-28 1989-06-06 Bausch & Lomb Incorporated Disinfecting and preserving systems and methods of use
FR2588189B1 (fr) * 1985-10-03 1988-12-02 Merck Sharp & Dohme Composition pharmaceutique de type a transition de phase liquide-gel
US4822819A (en) * 1986-11-07 1989-04-18 Alcon Laboratories, Inc. Use of trimoprostil and derivatives in glaucoma therapy
US4822820A (en) * 1986-11-24 1989-04-18 Alcon Laboratories, Inc. Use of tri-methyl PG-F2 a and derivatives in glaucoma therapy
US5110493A (en) * 1987-09-11 1992-05-05 Syntex (U.S.A.) Inc. Ophthalmic NSAID formulations containing a quaternary ammonium preservative and a nonionic surfactant
KR950013754B1 (ko) * 1987-09-11 1995-11-15 신텍스(미합중국)인코포레이티드 안과용 비스테로이드계 소염제제
IE63392B1 (en) * 1988-02-08 1995-04-19 Insite Vision Inc Ophthalmic suspensions
US5188826A (en) * 1988-02-08 1993-02-23 Insite Vision Incorporated Topical ophthalmic suspensions
US5149693A (en) * 1988-03-09 1992-09-22 Alcon Laboratories, Inc. Combination of tobramycin and fluorometholone for topical ophthalmic use
US5149694A (en) * 1988-03-09 1992-09-22 Alcon Laboratories, Inc. Combination of tobramycin and dexamethasone for topical ophthalmic use
US5173507A (en) * 1988-07-18 1992-12-22 Alcon Laboratories, Inc. Prostaglandin combinations in glaucoma therapy
US4960799A (en) * 1988-09-13 1990-10-02 Ciba-Geigy Corporation Stabilized aqueous solutions of pharmaceutically acceptable salts of ortho-(2,6-dichlorophenyl)-aminophenylacetic acid for opthalmic use
US5037647A (en) * 1988-09-15 1991-08-06 Alcon Laboratories, Inc. Aqueous antimicrobial opthalmic solutions comprised of quaternary ammonium compound, citric acid, citrate and sodium chloride
US5145643A (en) * 1990-01-05 1992-09-08 Allergan, Inc. Nonoxidative ophthalmic compositions and methods for preserving and using same
EP0639070B2 (en) * 1992-05-06 2010-09-08 Alcon Laboratories, Inc. Use of borate-polyol complexes in ophthalmic compositions
US5300287A (en) * 1992-11-04 1994-04-05 Alcon Laboratories, Inc. Polymeric antimicrobials and their use in pharmaceutical compositions
WO1994015597A1 (en) * 1993-01-11 1994-07-21 Allergan, Inc. Ophthalmic compositions comprising benzyllauryldimethylammonium chloride

Also Published As

Publication number Publication date
AU686917B2 (en) 1998-02-12
EP0739197A1 (en) 1996-10-30
DE69522094D1 (de) 2001-09-13
WO1996014829A1 (en) 1996-05-23
US5603929A (en) 1997-02-18
JP2954356B2 (ja) 1999-09-27
AU4162296A (en) 1996-06-06
US5653972A (en) 1997-08-05
JPH09503791A (ja) 1997-04-15
DE69522094T2 (de) 2001-11-22
CA2180554C (en) 2001-08-21
DK0739197T3 (da) 2001-10-29
HK1012556A1 (en) 1999-08-06
GR3036622T3 (en) 2001-12-31
CA2180554A1 (en) 1996-05-23
PT739197E (pt) 2001-12-28
ATE203897T1 (de) 2001-08-15
EP0739197B1 (en) 2001-08-08

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