ATE203897T1 - Konservierungsmittelhaltige ophtalmisch anzuwendende arzneizusammensetzungen enthaltend quaternäre polymerammoniumverbindungen - Google Patents
Konservierungsmittelhaltige ophtalmisch anzuwendende arzneizusammensetzungen enthaltend quaternäre polymerammoniumverbindungenInfo
- Publication number
- ATE203897T1 ATE203897T1 AT95939996T AT95939996T ATE203897T1 AT E203897 T1 ATE203897 T1 AT E203897T1 AT 95939996 T AT95939996 T AT 95939996T AT 95939996 T AT95939996 T AT 95939996T AT E203897 T1 ATE203897 T1 AT E203897T1
- Authority
- AT
- Austria
- Prior art keywords
- ammonium compounds
- preservatively
- medicinal compositions
- compositions containing
- quaternary polymer
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/340,763 US5603929A (en) | 1994-11-16 | 1994-11-16 | Preserved ophthalmic drug compositions containing polymeric quaternary ammonium compounds |
| PCT/US1995/014910 WO1996014829A1 (en) | 1994-11-16 | 1995-11-16 | Preserved ophthalmic drug compositions containing polymeric quaternary ammonium compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE203897T1 true ATE203897T1 (de) | 2001-08-15 |
Family
ID=23334841
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95939996T ATE203897T1 (de) | 1994-11-16 | 1995-11-16 | Konservierungsmittelhaltige ophtalmisch anzuwendende arzneizusammensetzungen enthaltend quaternäre polymerammoniumverbindungen |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US5603929A (de) |
| EP (1) | EP0739197B1 (de) |
| JP (1) | JP2954356B2 (de) |
| AT (1) | ATE203897T1 (de) |
| AU (1) | AU686917B2 (de) |
| CA (1) | CA2180554C (de) |
| DE (1) | DE69522094T2 (de) |
| DK (1) | DK0739197T3 (de) |
| ES (1) | ES2160722T3 (de) |
| GR (1) | GR3036622T3 (de) |
| PT (1) | PT739197E (de) |
| WO (1) | WO1996014829A1 (de) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5505953A (en) * | 1992-05-06 | 1996-04-09 | Alcon Laboratories, Inc. | Use of borate-polyol complexes in ophthalmic compositions |
| US5683993A (en) * | 1995-06-22 | 1997-11-04 | Ciba Vision Corporation | Compositions and methods for stabilizing polymers |
| JP2000505486A (ja) * | 1996-02-14 | 2000-05-09 | アルコン ラボラトリーズ,インコーポレイテッド | ポリマー第4級アンモニウム化合物と、眼科用抗微生物剤としてのその使用 |
| EP0877600B1 (de) * | 1996-08-09 | 2003-10-22 | Alcon Manufacturing Ltd. | Konservierungssysteme fur cyclodextrine enthaltende arzneimittel |
| ATE326983T1 (de) | 1996-12-13 | 2006-06-15 | Alcon Lab Inc | Aminoalkohole enthaltende ophthalmische zusammensetzungen |
| ATE391492T1 (de) * | 1997-07-29 | 2008-04-15 | Alcon Lab Inc | Ophthalmische zusammensetzungen enthaltend galaktomannanpolymere und borat |
| JP4064625B2 (ja) | 1997-11-26 | 2008-03-19 | アドバンスト メディカル オプティクス, インコーポレーテッド | コンタクトレンズ洗浄組成物 |
| US6063745A (en) * | 1997-11-26 | 2000-05-16 | Allergan | Mutli-purpose contact lens care compositions |
| JPH11249087A (ja) * | 1997-12-18 | 1999-09-17 | Tome:Kk | コンタクトレンズ用液剤 |
| JP2006111636A (ja) * | 1997-12-26 | 2006-04-27 | Astellas Pharma Inc | 徐放性医薬組成物 |
| US7678836B2 (en) * | 1999-11-04 | 2010-03-16 | Fxs Ventures, Llc | Method for rendering a contact lens wettable |
| CA2395866C (en) | 2000-01-25 | 2009-10-13 | Alcon, Inc. | Ophthalmic anti-allergy compositions suitable for use with contact lenses |
| AR035509A1 (es) * | 2000-12-21 | 2004-06-02 | Alcon Inc | Solucion de lagrimas artificiales mejorada que contiene una combinacion de tres emolientes y el uso de dicha solucion para la fabricacion de un medicamento |
| US7923469B2 (en) | 2001-04-30 | 2011-04-12 | Allergen, Inc. | Compositions including vitamin-based surfactants and methods for using same |
| JP4286480B2 (ja) * | 2001-09-17 | 2009-07-01 | 株式会社メニコン | 殺菌液 |
| EP1586316B1 (de) | 2003-01-21 | 2008-04-30 | Senju Pharmaceutical Co., Ltd. | Wässrige flüssige zubereitung mit 2-amino-3-(4-bromobenzoyl)phenylessigsäure |
| CA2505836C (en) * | 2004-05-06 | 2013-08-27 | Alcon Inc. | Topical brimonidine tartrate formulations that lack chlorine dioxide |
| US20060073184A1 (en) * | 2004-09-29 | 2006-04-06 | Bausch & Lomb Inc. | Viscoelastic composition, methods of use and packaging device with anti-oxidant |
| CN1993118B (zh) | 2004-11-05 | 2010-06-16 | 千寿制药株式会社 | 促进眼内渗透性的水性滴眼剂 |
| JP5108234B2 (ja) * | 2005-02-07 | 2012-12-26 | 日本特殊陶業株式会社 | マイクロヒータ及びセンサ |
| US7947010B2 (en) | 2005-07-08 | 2011-05-24 | Depuy Products, Inc. | Composition and system for wound decontamination |
| US20100130580A1 (en) * | 2006-01-25 | 2010-05-27 | Aciex Therapeutics, Inc. | Formulations and Methods for Treating Dry Eye |
| CA2621616A1 (en) * | 2007-02-19 | 2008-08-19 | Alcon Research, Ltd. | Topical gatifloxacin formulations |
| US7705112B2 (en) | 2007-04-17 | 2010-04-27 | Abbott Medical Optics Inc. | Polyquaternium-1 synthesis methods |
| MX2009012645A (es) * | 2007-05-24 | 2010-03-08 | Aciex Therapeutics Inc | Formulaciones y metodos para tratar el ojo seco. |
| AU2008310956B2 (en) | 2007-10-08 | 2014-08-07 | Aurinia Pharmaceuticals Inc. | Ophthalmic compositions comprising calcineurin inhibitors or mTOR inhibitors |
| BRPI0908502A2 (pt) * | 2008-02-21 | 2017-05-23 | Ista Pharmaceuticals | aines oftálmicos como adjuvantes |
| US9192571B2 (en) | 2008-03-03 | 2015-11-24 | Allergan, Inc. | Ketorolac tromethamine compositions for treating or preventing ocular pain |
| RU2431469C1 (ru) * | 2008-03-03 | 2011-10-20 | Аллерган, Инк. | Композиции кеторолака трометамина для лечения или профилактики глазной боли |
| BRPI0909738A2 (pt) | 2008-03-17 | 2015-10-06 | Alcon Res Ltd | composições farmacêuticas aquosas contendo complexos de boratopoliol |
| TWI544927B (zh) | 2008-03-17 | 2016-08-11 | 愛爾康研究有限公司 | 具有低濃度的表面活性劑以促進治療劑之生物可利用性的藥學組成物 |
| TWI454289B (zh) * | 2008-04-03 | 2014-10-01 | Alcon Res Ltd | 使用順式二醇的聚合物於抑制陽離子殺生物劑被吸收進入水凝膠生物材質中之用途 |
| TW201038295A (en) * | 2009-04-17 | 2010-11-01 | Alcon Res Ltd | Aqueous ophthalmic compositions containing anionic therapeutic agents |
| MX338355B (es) | 2009-06-09 | 2016-04-13 | Aurinia Pharmaceuticals Inc | Sistemas de suministro de farmaco topico para uso oftalmico. |
| TWI489997B (zh) | 2009-06-19 | 2015-07-01 | Alcon Res Ltd | 含有硼酸-多元醇錯合物之水性藥學組成物 |
| WO2012099142A1 (ja) | 2011-01-18 | 2012-07-26 | 千寿製薬株式会社 | 保存効力を有するブロムフェナク水性液剤組成物 |
| JP6128572B2 (ja) * | 2012-11-19 | 2017-05-17 | ボシュ・アンド・ロム・インコーポレイテッドBausch & Lomb Incorporated | 2−アミノ−3−(4−ブロモベンゾイル)フェニル酢酸を含有する水性液体組成物 |
| US20160143869A1 (en) | 2013-06-19 | 2016-05-26 | Sentiss Research Center | Stable bromfenac solution |
| BR112016003692B1 (pt) | 2013-08-20 | 2022-02-08 | 3M Innovative Properties Company | Complexo poliéter boro-silano |
| WO2015087267A2 (en) | 2013-12-12 | 2015-06-18 | Sentiss Pharma Private Limited | Stable bromfenac ophthalmic solution |
| US10632202B2 (en) | 2016-03-04 | 2020-04-28 | Johnson & Johnson Consumer Inc. | Preservative containing compositions |
| US20190224275A1 (en) | 2017-05-12 | 2019-07-25 | Aurinia Pharmaceuticals Inc. | Protocol for treatment of lupus nephritis |
| US20230159202A1 (en) * | 2021-11-23 | 2023-05-25 | Bausch + Lomb Ireland Limited | Method for making a preservative-free packaged ophthalmic device product |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3931319A (en) * | 1974-10-29 | 1976-01-06 | Millmaster Onyx Corporation | Capped polymers |
| US4027020A (en) * | 1974-10-29 | 1977-05-31 | Millmaster Onyx Corporation | Randomly terminated capped polymers |
| US4136173A (en) * | 1977-01-31 | 1979-01-23 | American Home Products Corp. | Mixed xanthan gum and locust beam gum therapeutic compositions |
| US4136178A (en) * | 1977-01-31 | 1979-01-23 | American Home Products Corp. | Locust bean gum therapeutic compositions |
| US4136177A (en) * | 1977-01-31 | 1979-01-23 | American Home Products Corp. | Xanthan gum therapeutic compositions |
| FR2508440B1 (fr) * | 1981-06-25 | 1985-11-08 | Saint Gobain Isover | Procede de preparation d'alcools orthohydroxybenzyliques |
| US4407791A (en) * | 1981-09-28 | 1983-10-04 | Alcon Laboratories, Inc. | Ophthalmic solutions |
| US4525346A (en) * | 1981-09-28 | 1985-06-25 | Alcon Laboratories, Inc. | Aqueous antimicrobial ophthalmic solutions |
| US4836986A (en) * | 1984-09-28 | 1989-06-06 | Bausch & Lomb Incorporated | Disinfecting and preserving systems and methods of use |
| FR2588189B1 (fr) * | 1985-10-03 | 1988-12-02 | Merck Sharp & Dohme | Composition pharmaceutique de type a transition de phase liquide-gel |
| US4822819A (en) * | 1986-11-07 | 1989-04-18 | Alcon Laboratories, Inc. | Use of trimoprostil and derivatives in glaucoma therapy |
| US4822820A (en) * | 1986-11-24 | 1989-04-18 | Alcon Laboratories, Inc. | Use of tri-methyl PG-F2 a and derivatives in glaucoma therapy |
| ZA886757B (en) * | 1987-09-11 | 1990-05-30 | Syntex Inc | Preservative system for ophthalmics formulations |
| US5110493A (en) * | 1987-09-11 | 1992-05-05 | Syntex (U.S.A.) Inc. | Ophthalmic NSAID formulations containing a quaternary ammonium preservative and a nonionic surfactant |
| US5188826A (en) * | 1988-02-08 | 1993-02-23 | Insite Vision Incorporated | Topical ophthalmic suspensions |
| IE63392B1 (en) * | 1988-02-08 | 1995-04-19 | Insite Vision Inc | Ophthalmic suspensions |
| US5149693A (en) * | 1988-03-09 | 1992-09-22 | Alcon Laboratories, Inc. | Combination of tobramycin and fluorometholone for topical ophthalmic use |
| US5149694A (en) * | 1988-03-09 | 1992-09-22 | Alcon Laboratories, Inc. | Combination of tobramycin and dexamethasone for topical ophthalmic use |
| US5173507A (en) * | 1988-07-18 | 1992-12-22 | Alcon Laboratories, Inc. | Prostaglandin combinations in glaucoma therapy |
| US4960799A (en) * | 1988-09-13 | 1990-10-02 | Ciba-Geigy Corporation | Stabilized aqueous solutions of pharmaceutically acceptable salts of ortho-(2,6-dichlorophenyl)-aminophenylacetic acid for opthalmic use |
| US5037647A (en) * | 1988-09-15 | 1991-08-06 | Alcon Laboratories, Inc. | Aqueous antimicrobial opthalmic solutions comprised of quaternary ammonium compound, citric acid, citrate and sodium chloride |
| US5145643A (en) * | 1990-01-05 | 1992-09-08 | Allergan, Inc. | Nonoxidative ophthalmic compositions and methods for preserving and using same |
| ATE300936T1 (de) * | 1992-05-06 | 2005-08-15 | Alcon Lab Inc | Anwendung von boral-polyol-komplexen für ophthalmische arzneizusammensetzungen |
| US5300287A (en) * | 1992-11-04 | 1994-04-05 | Alcon Laboratories, Inc. | Polymeric antimicrobials and their use in pharmaceutical compositions |
| WO1994015597A1 (en) * | 1993-01-11 | 1994-07-21 | Allergan, Inc. | Ophthalmic compositions comprising benzyllauryldimethylammonium chloride |
-
1994
- 1994-11-16 US US08/340,763 patent/US5603929A/en not_active Expired - Lifetime
-
1995
- 1995-11-16 ES ES95939996T patent/ES2160722T3/es not_active Expired - Lifetime
- 1995-11-16 AT AT95939996T patent/ATE203897T1/de active
- 1995-11-16 DK DK95939996T patent/DK0739197T3/da active
- 1995-11-16 WO PCT/US1995/014910 patent/WO1996014829A1/en not_active Ceased
- 1995-11-16 AU AU41622/96A patent/AU686917B2/en not_active Expired
- 1995-11-16 CA CA002180554A patent/CA2180554C/en not_active Expired - Lifetime
- 1995-11-16 JP JP8509750A patent/JP2954356B2/ja not_active Expired - Lifetime
- 1995-11-16 DE DE69522094T patent/DE69522094T2/de not_active Expired - Lifetime
- 1995-11-16 EP EP95939996A patent/EP0739197B1/de not_active Expired - Lifetime
- 1995-11-16 PT PT95939996T patent/PT739197E/pt unknown
-
1996
- 1996-08-21 US US08/700,960 patent/US5653972A/en not_active Expired - Lifetime
-
2001
- 2001-09-17 GR GR20010401480T patent/GR3036622T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2180554C (en) | 2001-08-21 |
| JP2954356B2 (ja) | 1999-09-27 |
| DK0739197T3 (da) | 2001-10-29 |
| AU686917B2 (en) | 1998-02-12 |
| DE69522094D1 (de) | 2001-09-13 |
| AU4162296A (en) | 1996-06-06 |
| HK1012556A1 (en) | 1999-08-06 |
| PT739197E (pt) | 2001-12-28 |
| EP0739197A1 (de) | 1996-10-30 |
| GR3036622T3 (en) | 2001-12-31 |
| DE69522094T2 (de) | 2001-11-22 |
| US5603929A (en) | 1997-02-18 |
| EP0739197B1 (de) | 2001-08-08 |
| CA2180554A1 (en) | 1996-05-23 |
| US5653972A (en) | 1997-08-05 |
| ES2160722T3 (es) | 2001-11-16 |
| JPH09503791A (ja) | 1997-04-15 |
| WO1996014829A1 (en) | 1996-05-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |