ES2154744T3 - Formulaciones de comprimidos farmaceuticos para compresion directa. - Google Patents

Formulaciones de comprimidos farmaceuticos para compresion directa.

Info

Publication number
ES2154744T3
ES2154744T3 ES95942265T ES95942265T ES2154744T3 ES 2154744 T3 ES2154744 T3 ES 2154744T3 ES 95942265 T ES95942265 T ES 95942265T ES 95942265 T ES95942265 T ES 95942265T ES 2154744 T3 ES2154744 T3 ES 2154744T3
Authority
ES
Spain
Prior art keywords
direct compression
formulations
pharmaceutically active
active principle
pharmaceutical tablets
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95942265T
Other languages
English (en)
Spanish (es)
Inventor
Paul Mccarthy
Ann Donegan
John Pattison
Richard O'sullivan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ENBALT TRADING Ltd
Bioglan Ireland R&D Ltd
Original Assignee
ENBALT TRADING Ltd
Bioglan Ireland R&D Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IES950586 external-priority patent/IES950586A2/xx
Application filed by ENBALT TRADING Ltd, Bioglan Ireland R&D Ltd filed Critical ENBALT TRADING Ltd
Application granted granted Critical
Publication of ES2154744T3 publication Critical patent/ES2154744T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Emergency Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES95942265T 1994-12-14 1995-12-14 Formulaciones de comprimidos farmaceuticos para compresion directa. Expired - Lifetime ES2154744T3 (es)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
IE940969 1994-12-14
IE940971 1994-12-14
IES950586 IES950586A2 (en) 1995-07-31 1995-07-31 Pharmaceutical processing
IE950583 1995-07-31
IE950584 1995-07-31
PCT/IE1995/000062 WO1996018386A1 (en) 1994-12-14 1995-12-14 Pharmaceutical tablet formulations for direct compression

Publications (1)

Publication Number Publication Date
ES2154744T3 true ES2154744T3 (es) 2001-04-16

Family

ID=27517559

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95942265T Expired - Lifetime ES2154744T3 (es) 1994-12-14 1995-12-14 Formulaciones de comprimidos farmaceuticos para compresion directa.

Country Status (11)

Country Link
EP (2) EP1057479A1 (da)
AT (1) ATE199495T1 (da)
AU (1) AU4353996A (da)
DE (1) DE69520292T2 (da)
DK (1) DK0800384T3 (da)
ES (1) ES2154744T3 (da)
GB (1) GB2295966B (da)
GR (1) GR3035863T3 (da)
IE (1) IE950946A1 (da)
PT (1) PT800384E (da)
WO (1) WO1996018386A1 (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2352430C (en) 1998-12-01 2008-11-18 Novo Nordisk A/S New pharmaceutical composition and the process for its preparation
WO2001089523A1 (en) 2000-05-26 2001-11-29 Novo Nordisk A/S New pharmaceutical composition and the process for its preparation
AU2000249111A1 (en) * 2000-05-30 2001-12-11 Dr. Reddy's Research Foundation New pharmaceutical composition and the process for its preparation
AU2005202705B2 (en) * 2000-12-06 2006-06-15 Novartis Ag Pharmaceutical compositions for the oral delivery of pharmacologically active agents
US7049283B2 (en) * 2000-12-06 2006-05-23 Novartis Ag Pharmaceutical compositions for the oral delivery of pharmacologically active agents
RU2207128C2 (ru) * 2001-07-05 2003-06-27 Закрытое акционерное общество "ВЕРОФАРМ" Диуретическое и гипотензивное средство
RU2191572C1 (ru) * 2001-09-26 2002-10-27 Нестерук Владимир Викторович Диуретическое и гипотензивное средство в виде таблетки
PL193976B1 (pl) * 2002-07-01 2007-04-30 Pliva Krakow Tabletka o przedłużonym działaniu zawierająca indapamid i sposób wytwarzania tabletki o przedłużonym działaniu zawierającej indapamid
RU2286779C2 (ru) * 2003-02-06 2006-11-10 Закрытое акционерное общество "Фармацевтическое предприятие "Оболенское" Лекарственная форма, обладающая диуретическим и антигипертензивным действием, и способ ее изготовления
DE102004005009A1 (de) * 2004-01-30 2005-09-01 Krka Tovarna Zdravil, D.D. Verzögert freisetzende pharmazeutische Zusammensetzung von Indapamid
DE102004062257A1 (de) * 2004-12-23 2006-07-06 Merckle Gmbh Direkt verpresste Indapamid-Tabletten mit verzögerter Wirkstofffreisetzung
NZ612787A (en) 2005-10-25 2015-01-30 Resmed Ltd Interchangeable mask assembly

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4517179A (en) * 1983-04-29 1985-05-14 Pennwalt Corporation Rapid dissolving, uniform drug compositions and their preparation
US4639458A (en) * 1985-01-22 1987-01-27 Merck & Co., Inc. Tablet and formulation
ES2058288T3 (es) * 1987-07-08 1994-11-01 American Home Prod Composiciones de ibuprofen secadas por atomizacion.
US4792452A (en) * 1987-07-28 1988-12-20 E. R. Squibb & Sons, Inc. Controlled release formulation
HU208484B (en) * 1988-08-17 1993-11-29 Chinoin Gyogyszer Es Vegyeszet Process for producing pharmaceutical composition containing acid additional salt of selegilin as active component for treating schisofrenia
US5047246A (en) * 1988-09-09 1991-09-10 Bristol-Myers Company Direct compression cyclophosphamide tablet
DE3941703C2 (de) * 1989-12-18 2002-11-07 Sanol Arznei Schwarz Gmbh Bumetanid enthaltende pharmazeutische Zubereitung
US5358717A (en) * 1989-12-22 1994-10-25 Syntex (U.S.A.) Inc. Directly-compressible naproxen or naproxen sodium compositions
US5057321A (en) * 1990-06-13 1991-10-15 Alza Corporation Dosage form comprising drug and maltodextrin
FR2669221B1 (fr) * 1990-11-15 1993-01-15 Rhone Poulenc Sante Procede de preparation par compression directe de comprimes de derives de l'acide cephalosporanique.
SK117793A3 (en) * 1991-04-29 1994-05-11 Merck & Co Inc Optimized tablet formulation
FR2677886B1 (fr) * 1991-06-18 1995-03-31 Adir Comprime matriciel permettant la liberation prolongee d'indapamide apres administration par voie orale.
ZA933349B (en) * 1992-05-13 1994-06-15 Alza Corp Transdermal administration of oxybutynin
US5358941A (en) * 1992-12-02 1994-10-25 Merck & Co., Inc. Dry mix formulation for bisphosphonic acids with lactose
SE9301112D0 (sv) * 1993-04-02 1993-04-02 Orion-Yhtymae Oy A new composition
CA2125251C (en) * 1993-06-07 2005-04-26 Yoshiyuki Inada A pharmaceutical composition for angiotensin ii-mediated diseases
JPH08511009A (ja) * 1993-06-08 1996-11-19 チバ−ガイギー アクチェンゲゼルシャフト ジクロフェナックを含有する経口固体剤形の製造方法
ZA939566B (en) * 1993-12-21 1994-08-11 Applied Analytical Ind Inc Method for dry blend compression od medicaments.

Also Published As

Publication number Publication date
GB2295966A (en) 1996-06-19
DK0800384T3 (da) 2001-04-17
EP0800384A1 (en) 1997-10-15
EP1057479A1 (en) 2000-12-06
GB2295966B (en) 1997-09-24
IE950946A1 (en) 1996-06-26
GB9525598D0 (en) 1996-02-14
GR3035863T3 (en) 2001-08-31
DE69520292T2 (de) 2001-06-13
EP0800384B1 (en) 2001-03-07
DE69520292D1 (de) 2001-04-12
WO1996018386A1 (en) 1996-06-20
PT800384E (pt) 2001-06-29
ATE199495T1 (de) 2001-03-15
AU4353996A (en) 1996-07-03

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