ES2154176A1 - Nuevo procedimiento de obtencion de 3-(hidroximetil)cromen-4-onas. - Google Patents

Nuevo procedimiento de obtencion de 3-(hidroximetil)cromen-4-onas.

Info

Publication number
ES2154176A1
ES2154176A1 ES009801970A ES9801970A ES2154176A1 ES 2154176 A1 ES2154176 A1 ES 2154176A1 ES 009801970 A ES009801970 A ES 009801970A ES 9801970 A ES9801970 A ES 9801970A ES 2154176 A1 ES2154176 A1 ES 2154176A1
Authority
ES
Spain
Prior art keywords
chromen
hydroxymethyl
ones
preparation
halogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES009801970A
Other languages
English (en)
Other versions
ES2154176B1 (es
Inventor
Ambros Rafael Foguet
Gener Jordi Bolos
Munoz Aurelio Sacristan
Barenys Josep Maria Castello
Hernandez Jose A Ortiz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ferrer Internacional SA
Original Assignee
Ferrer Internacional SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferrer Internacional SA filed Critical Ferrer Internacional SA
Priority to ES009801970A priority Critical patent/ES2154176B1/es
Priority to TW088115637A priority patent/TW480254B/zh
Priority to ZA9905877A priority patent/ZA995877B/xx
Priority to ARP990104580A priority patent/AR017003A1/es
Priority to US09/787,113 priority patent/US6348605B1/en
Priority to DE69915498T priority patent/DE69915498T2/de
Priority to PCT/EP1999/006946 priority patent/WO2000017183A1/en
Priority to IL14175199A priority patent/IL141751A/xx
Priority to NZ510309A priority patent/NZ510309A/en
Priority to KR1020017003562A priority patent/KR100547939B1/ko
Priority to AU10331/00A priority patent/AU754043B2/en
Priority to CA002344664A priority patent/CA2344664C/en
Priority to EP99953745A priority patent/EP1115717B1/en
Priority to DK99953745T priority patent/DK1115717T3/da
Priority to PT99953745T priority patent/PT1115717E/pt
Priority to BRPI9914009-8A priority patent/BR9914009B1/pt
Priority to AT99953745T priority patent/ATE261437T1/de
Priority to JP2000574093A priority patent/JP3983979B2/ja
Publication of ES2154176A1 publication Critical patent/ES2154176A1/es
Priority to NO20011401A priority patent/NO327046B1/no
Application granted granted Critical
Publication of ES2154176B1 publication Critical patent/ES2154176B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

Nuevo procedimiento de obtención de 3-(hidroximetil)cromen-4- onas. Consiste en hacer reaccionar los compuestos de fórmula general (II) donde R significa hidrógeno, halógeno, alquilo cuyo número de carbonos está comprendido entre 1 y 4 o alcoxi cuyo número de carbonos está comprendido entre 1 y 4, opcionalmente substituido por fenil o por halógeno, con formaldehído y un catalizador básico seguido de acidificación, con lo cual se obtienen las 3-(hidroximetil)cromen-4-onas de fórmula general (I) donde R tiene igual significado que en (II).
ES009801970A 1998-09-21 1998-09-21 Nuevo procedimiento de obtencion de 3-(hidroximetil)cromen-4-onas. Expired - Fee Related ES2154176B1 (es)

Priority Applications (19)

Application Number Priority Date Filing Date Title
ES009801970A ES2154176B1 (es) 1998-09-21 1998-09-21 Nuevo procedimiento de obtencion de 3-(hidroximetil)cromen-4-onas.
TW088115637A TW480254B (en) 1998-09-21 1999-09-10 Process for preparing 3-(hydroxymethyl) chromen-4-ones
ARP990104580A AR017003A1 (es) 1998-09-21 1999-09-13 Procedimiento de obtencion de 3-(hidrometil)cromen-4-onas
ZA9905877A ZA995877B (en) 1998-09-21 1999-09-13 Process for preparing 3-(hydroxymethyl)chromen-4-ones.
DK99953745T DK1115717T3 (da) 1998-09-21 1999-09-20 3-(hydroxymethyl)chromen-4-oner samt fremgangsmåde til fremstilling heraf
PCT/EP1999/006946 WO2000017183A1 (en) 1998-09-21 1999-09-20 3-(hydroxymethyl)chromen-4-ones and process for preparing
IL14175199A IL141751A (en) 1998-09-21 1999-09-20 Process for preparing 3-(hydroxymethyl) chromen-4-ones
NZ510309A NZ510309A (en) 1998-09-21 1999-09-20 A process for preparing 3-(hydroxymethyl)chromen-4-ones and 3-(hydroxymethyl)chromen-4-ones prepared by this process
KR1020017003562A KR100547939B1 (ko) 1998-09-21 1999-09-20 3-(히드록시메틸)크로멘-4-온의 제조공정
AU10331/00A AU754043B2 (en) 1998-09-21 1999-09-20 3-(hydroxymethyl)chromen-4-ones and process for preparing
US09/787,113 US6348605B1 (en) 1998-09-21 1999-09-20 Process for preparing 3-hydroxymethyl chromen-4-ones
EP99953745A EP1115717B1 (en) 1998-09-21 1999-09-20 3-(hydroxymethyl)chromen-4-ones and process for their preparation
DE69915498T DE69915498T2 (de) 1998-09-21 1999-09-20 3-(hydroxymethyl)chromen-4-one und verfahren zu deren herstellung
PT99953745T PT1115717E (pt) 1998-09-21 1999-09-20 3-(hidroximetil)cromen-4-onas e processo para a sua preparacao
BRPI9914009-8A BR9914009B1 (pt) 1998-09-21 1999-09-20 processo para preparaÇço de 3-(hidroximetil) cromen-4-onas.
AT99953745T ATE261437T1 (de) 1998-09-21 1999-09-20 3-(hydroxymethyl)chromen-4-one und verfahren zu deren herstellung
JP2000574093A JP3983979B2 (ja) 1998-09-21 1999-09-20 ３−（ヒドロキシメチル）クロメン−４−オン類およびその製造方法
CA002344664A CA2344664C (en) 1998-09-21 1999-09-20 Process for preparing 3-(hydroxymethyl)chromen-4-ones
NO20011401A NO327046B1 (no) 1998-09-21 2001-03-20 Fremgangsmate for fremstilling av 3-(hydroksymetyl)kromen-4-oner

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES009801970A ES2154176B1 (es) 1998-09-21 1998-09-21 Nuevo procedimiento de obtencion de 3-(hidroximetil)cromen-4-onas.

Publications (2)

Publication Number Publication Date
ES2154176A1 true ES2154176A1 (es) 2001-03-16
ES2154176B1 ES2154176B1 (es) 2001-10-16

Family

ID=8305211

Family Applications (1)

Application Number Title Priority Date Filing Date
ES009801970A Expired - Fee Related ES2154176B1 (es) 1998-09-21 1998-09-21 Nuevo procedimiento de obtencion de 3-(hidroximetil)cromen-4-onas.

Country Status (19)

Country Link
US (1) US6348605B1 (es)
EP (1) EP1115717B1 (es)
JP (1) JP3983979B2 (es)
KR (1) KR100547939B1 (es)
AR (1) AR017003A1 (es)
AT (1) ATE261437T1 (es)
AU (1) AU754043B2 (es)
BR (1) BR9914009B1 (es)
CA (1) CA2344664C (es)
DE (1) DE69915498T2 (es)
DK (1) DK1115717T3 (es)
ES (1) ES2154176B1 (es)
IL (1) IL141751A (es)
NO (1) NO327046B1 (es)
NZ (1) NZ510309A (es)
PT (1) PT1115717E (es)
TW (1) TW480254B (es)
WO (1) WO2000017183A1 (es)
ZA (1) ZA995877B (es)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3887584A (en) * 1972-11-24 1975-06-03 Warner Lambert Co 3-(Hydroxymethyl)chromones
ES2101644A1 (es) * 1994-03-18 1997-07-01 Ferrer Int Nuevo compuesto derivado del cromeno
ES2103237A1 (es) * 1995-04-12 1997-09-01 Ferrerinternacional S A Nuevo compuesto derivado del cromeno

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2378573A (en) * 1939-07-08 1945-06-19 Natta Giulio Process for the manufacture of keto-alcohols
IL112764A0 (en) 1994-03-18 1995-05-26 Ferrer Int New chromene derivatives

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3887584A (en) * 1972-11-24 1975-06-03 Warner Lambert Co 3-(Hydroxymethyl)chromones
ES2101644A1 (es) * 1994-03-18 1997-07-01 Ferrer Int Nuevo compuesto derivado del cromeno
ES2103237A1 (es) * 1995-04-12 1997-09-01 Ferrerinternacional S A Nuevo compuesto derivado del cromeno

Also Published As

Publication number Publication date
KR100547939B1 (ko) 2006-02-02
NO20011401L (no) 2001-03-20
CA2344664C (en) 2006-11-07
PT1115717E (pt) 2004-07-30
TW480254B (en) 2002-03-21
EP1115717A1 (en) 2001-07-18
IL141751A0 (en) 2002-03-10
AR017003A1 (es) 2001-08-22
KR20010075229A (ko) 2001-08-09
DE69915498D1 (de) 2004-04-15
WO2000017183A1 (en) 2000-03-30
JP2002526487A (ja) 2002-08-20
ATE261437T1 (de) 2004-03-15
AU754043B2 (en) 2002-10-31
NZ510309A (en) 2002-06-28
IL141751A (en) 2005-03-20
AU1033100A (en) 2000-04-10
BR9914009B1 (pt) 2010-02-09
DE69915498T2 (de) 2004-08-19
JP3983979B2 (ja) 2007-09-26
ES2154176B1 (es) 2001-10-16
BR9914009A (pt) 2001-07-03
NO327046B1 (no) 2009-04-14
EP1115717B1 (en) 2004-03-10
US6348605B1 (en) 2002-02-19
DK1115717T3 (da) 2004-07-12
NO20011401D0 (no) 2001-03-20
CA2344664A1 (en) 2000-03-30
ZA995877B (en) 2001-01-02

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