ES2148826T3 - Metodo para tratar una lesion ganglionar de la retina usando un producto proteinico de factor neurotrofico obtenido de la linea celular glialica (gdnf). - Google Patents
Metodo para tratar una lesion ganglionar de la retina usando un producto proteinico de factor neurotrofico obtenido de la linea celular glialica (gdnf).Info
- Publication number
- ES2148826T3 ES2148826T3 ES96942805T ES96942805T ES2148826T3 ES 2148826 T3 ES2148826 T3 ES 2148826T3 ES 96942805 T ES96942805 T ES 96942805T ES 96942805 T ES96942805 T ES 96942805T ES 2148826 T3 ES2148826 T3 ES 2148826T3
- Authority
- ES
- Spain
- Prior art keywords
- gdnf
- treating
- neurotrophic factor
- glialic
- ganglionar
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000006378 damage Effects 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 102000034615 Glial cell line-derived neurotrophic factor Human genes 0.000 title abstract 2
- 108091010837 Glial cell line-derived neurotrophic factor Proteins 0.000 title abstract 2
- 108010025020 Nerve Growth Factor Proteins 0.000 title abstract 2
- 102000007072 Nerve Growth Factors Human genes 0.000 title abstract 2
- 208000027418 Wounds and injury Diseases 0.000 title 1
- 208000014674 injury Diseases 0.000 title 1
- 210000001525 retina Anatomy 0.000 title 1
- 230000007850 degeneration Effects 0.000 abstract 2
- 208000010412 Glaucoma Diseases 0.000 abstract 1
- 210000004498 neuroglial cell Anatomy 0.000 abstract 1
- 239000003900 neurotrophic factor Substances 0.000 abstract 1
- 210000001328 optic nerve Anatomy 0.000 abstract 1
- 210000003994 retinal ganglion cell Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Psychology (AREA)
- Ophthalmology & Optometry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
LA PRESENTE INVENCION TRATA EN GENERAL DE PROCEDIMIENTOS PARA TRATAR LESIONES O DEGENERACION DE CELULAS GANGLIONARES RETINIANAS MEDIANTE LA ADMINISTRACION DEL FACTOR NEUROTROFICO DERIVADO DE UNA LINEA DE CELULAS GLIALES (GDNF). LA INVENCION TRATA DE FORMA ESPECIFICS DE PROCEDIMIENTOS PARA TRATAR LAS LESIONES DEL NERVIO OPTICO O LA DEGENERACION ASOCIADA CON EL GLAUCOMA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/564,458 US5641749A (en) | 1995-11-29 | 1995-11-29 | Method for treating retinal ganglion cell injury using glial cell line-derived neurothrophic factor (GDNF) protein product |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2148826T3 true ES2148826T3 (es) | 2000-10-16 |
Family
ID=24254557
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES96942805T Expired - Lifetime ES2148826T3 (es) | 1995-11-29 | 1996-11-22 | Metodo para tratar una lesion ganglionar de la retina usando un producto proteinico de factor neurotrofico obtenido de la linea celular glialica (gdnf). |
Country Status (20)
Country | Link |
---|---|
US (1) | US5641749A (es) |
EP (1) | EP0866719B1 (es) |
JP (1) | JP4066201B2 (es) |
KR (1) | KR19990071541A (es) |
CN (1) | CN1203531A (es) |
AT (1) | ATE194081T1 (es) |
BR (1) | BR9611748A (es) |
CA (1) | CA2236158C (es) |
CZ (1) | CZ149998A3 (es) |
DE (1) | DE69609084T2 (es) |
DK (1) | DK0866719T3 (es) |
ES (1) | ES2148826T3 (es) |
GR (1) | GR3034194T3 (es) |
HU (1) | HUP0001078A2 (es) |
IL (1) | IL124600A0 (es) |
MX (1) | MX9803968A (es) |
NO (1) | NO982276L (es) |
PT (1) | PT866719E (es) |
SK (1) | SK65898A3 (es) |
WO (1) | WO1997019695A1 (es) |
Families Citing this family (64)
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US20020064870A1 (en) * | 1993-03-03 | 2002-05-30 | Pascale Briand | Recombinant adenoviruses and use thereof in gene therapy for treating eye diseases |
FR2704556B1 (fr) | 1993-04-30 | 1995-07-13 | Rhone Poulenc Rorer Sa | Virus recombinants et leur utilisation en thérapie génique. |
FR2710846B1 (fr) | 1993-10-04 | 1995-12-22 | Rhone Poulenc Rorer Sa | Compositions pharmaceutiques et leur utilisation, notamment dans le traitement des maladies neurogénératives. |
US8431119B2 (en) * | 1993-10-04 | 2013-04-30 | Aventis Pharma S.A. | Pharmaceutical compositions and utilization thereof particularly for the treatment of neurodegenerative diseases |
US5731284A (en) * | 1995-09-28 | 1998-03-24 | Amgen Inc. | Method for treating Alzheimer's disease using glial line-derived neurotrophic factor (GDNF) protein product |
US6184200B1 (en) * | 1995-09-28 | 2001-02-06 | Amgen Inc. | Truncated glial cell line-derived neurotrophic factor |
US5641750A (en) * | 1995-11-29 | 1997-06-24 | Amgen Inc. | Methods for treating photoreceptors using glial cell line-derived neurotrophic factor (GDNF) protein product |
US5741778A (en) * | 1996-03-19 | 1998-04-21 | Amgen Inc. | Method for treating Huntington's disease using glial cell line-derived neurotrophic factor (GDNF) protein product |
KR100236771B1 (ko) * | 1997-04-01 | 2000-02-01 | 성재갑 | 히아루론산을 이용한 약물의 서방성 미세입자 제형 |
US7276251B2 (en) * | 1997-04-01 | 2007-10-02 | Lg Life Sciences, Ltd., Inc. | Sustained-release composition of drugs encapsulated in microparticles of hyaluronic acid |
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WO1998010785A1 (fr) * | 1996-09-13 | 1998-03-19 | Advanced Medicine Research Institute | Compositions ophtalmiques de facteurs neurotrophiques, remedes pour troubles fonctionnels du nerf optique et procede de traitement de tels troubles |
IT1291892B1 (it) * | 1997-04-24 | 1999-01-21 | Alessandro Lambiase | Uso del nerve growth factor nella conservazione di cornee in coltura, nella produzione di tessuti corneali e congiuntivali in vitro e nella |
US20030121064A1 (en) * | 1997-06-11 | 2003-06-26 | Ann Logan | CNS neuroregenerative compositions and methods of use |
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US6339101B1 (en) | 1998-08-14 | 2002-01-15 | Gpi Nil Holdings, Inc. | N-linked sulfonamides of N-heterocyclic carboxylic acids or isosteres for vision and memory disorders |
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US6333340B1 (en) | 1998-08-14 | 2001-12-25 | Gpi Nil Holdings, Inc. | Small molecule sulfonamides for vision and memory disorders |
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US6337340B1 (en) | 1998-08-14 | 2002-01-08 | Gpi Nil Holdings, Inc. | Carboxylic acids and isosteres of heterocyclic ring compounds having multiple heteroatoms for vision and memory disorders |
US7265150B1 (en) | 1998-08-14 | 2007-09-04 | Gpi Nil Holdings Inc. | Carboxylic acids and carboxylic acid isosteres of N-heterocyclic compounds for vision and memory disorders |
US6399648B1 (en) | 1998-08-14 | 2002-06-04 | Gpi Nil Holdings, Inc. | N-oxides of heterocyclic ester, amide, thioester, or ketone for vision and memory disorders |
US6384056B1 (en) | 1998-08-14 | 2002-05-07 | Gpi Nil Holdings, Inc. | Heterocyclic thioesters or ketones for vision and memory disorders |
US7338976B1 (en) | 1998-08-14 | 2008-03-04 | Gpi Nil Holdings, Inc. | Heterocyclic esters or amides for vision and memory disorders |
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IT1305294B1 (it) | 1999-01-29 | 2001-05-04 | Alessandro Lambiase | Uso del nerve growth factor nella terapia di patologie a carico deitessuti intraoculari. |
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US6943153B1 (en) | 1999-03-15 | 2005-09-13 | The Regents Of The University Of California | Use of recombinant gene delivery vectors for treating or preventing diseases of the eye |
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US20030158112A1 (en) * | 2002-02-15 | 2003-08-21 | Johns Hopkins University School Of Medicine | Selective induction of apoptosis to treat ocular disease |
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GB2545763A (en) | 2015-12-23 | 2017-06-28 | Adverum Biotechnologies Inc | Mutant viral capsid libraries and related systems and methods |
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-
1995
- 1995-11-29 US US08/564,458 patent/US5641749A/en not_active Expired - Lifetime
-
1996
- 1996-11-22 PT PT96942805T patent/PT866719E/pt unknown
- 1996-11-22 SK SK658-98A patent/SK65898A3/sk unknown
- 1996-11-22 KR KR1019980703815A patent/KR19990071541A/ko not_active Application Discontinuation
- 1996-11-22 CA CA002236158A patent/CA2236158C/en not_active Expired - Fee Related
- 1996-11-22 DE DE69609084T patent/DE69609084T2/de not_active Expired - Lifetime
- 1996-11-22 AT AT96942805T patent/ATE194081T1/de active
- 1996-11-22 BR BR9611748A patent/BR9611748A/pt not_active Application Discontinuation
- 1996-11-22 JP JP52058297A patent/JP4066201B2/ja not_active Expired - Fee Related
- 1996-11-22 EP EP96942805A patent/EP0866719B1/en not_active Expired - Lifetime
- 1996-11-22 CZ CZ981499A patent/CZ149998A3/cs unknown
- 1996-11-22 DK DK96942805T patent/DK0866719T3/da active
- 1996-11-22 CN CN96198645A patent/CN1203531A/zh active Pending
- 1996-11-22 IL IL12460096A patent/IL124600A0/xx unknown
- 1996-11-22 ES ES96942805T patent/ES2148826T3/es not_active Expired - Lifetime
- 1996-11-22 HU HU0001078A patent/HUP0001078A2/hu unknown
- 1996-11-22 WO PCT/US1996/018851 patent/WO1997019695A1/en not_active Application Discontinuation
-
1998
- 1998-05-19 NO NO982276A patent/NO982276L/no unknown
- 1998-05-19 MX MX9803968A patent/MX9803968A/es unknown
-
2000
- 2000-08-14 GR GR20000401888T patent/GR3034194T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
AU696772B2 (en) | 1998-09-17 |
WO1997019695A1 (en) | 1997-06-05 |
DK0866719T3 (da) | 2000-08-28 |
NO982276D0 (no) | 1998-05-19 |
JP4066201B2 (ja) | 2008-03-26 |
SK65898A3 (en) | 1999-01-11 |
US5641749A (en) | 1997-06-24 |
CA2236158A1 (en) | 1997-06-05 |
NO982276L (no) | 1998-07-29 |
DE69609084D1 (de) | 2000-08-03 |
CN1203531A (zh) | 1998-12-30 |
KR19990071541A (ko) | 1999-09-27 |
BR9611748A (pt) | 1999-06-01 |
ATE194081T1 (de) | 2000-07-15 |
IL124600A0 (en) | 1998-12-06 |
HUP0001078A2 (hu) | 2000-08-28 |
CZ149998A3 (cs) | 1998-08-12 |
MX9803968A (es) | 1998-09-30 |
AU1163197A (en) | 1997-06-19 |
EP0866719B1 (en) | 2000-06-28 |
PT866719E (pt) | 2000-11-30 |
CA2236158C (en) | 2002-07-16 |
EP0866719A1 (en) | 1998-09-30 |
GR3034194T3 (en) | 2000-11-30 |
JP2000501393A (ja) | 2000-02-08 |
DE69609084T2 (de) | 2000-11-16 |
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