ES2147808T3 - Procedimiento para la obtencion de derivados de acido 4-metiliden-cinamico, asi como nuevos derivados de acido metilidencinamico. - Google Patents
Procedimiento para la obtencion de derivados de acido 4-metiliden-cinamico, asi como nuevos derivados de acido metilidencinamico.Info
- Publication number
- ES2147808T3 ES2147808T3 ES95110193T ES95110193T ES2147808T3 ES 2147808 T3 ES2147808 T3 ES 2147808T3 ES 95110193 T ES95110193 T ES 95110193T ES 95110193 T ES95110193 T ES 95110193T ES 2147808 T3 ES2147808 T3 ES 2147808T3
- Authority
- ES
- Spain
- Prior art keywords
- sub
- acid
- alkyl
- formula
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
- B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
- B01J31/24—Phosphines, i.e. phosphorus bonded to only carbon atoms, or to both carbon and hydrogen atoms, including e.g. sp2-hybridised phosphorus compounds such as phosphabenzene, phosphole or anionic phospholide ligands
- B01J31/2404—Cyclic ligands, including e.g. non-condensed polycyclic ligands, the phosphine-P atom being a ring member or a substituent on the ring
- B01J31/2409—Cyclic ligands, including e.g. non-condensed polycyclic ligands, the phosphine-P atom being a ring member or a substituent on the ring with more than one complexing phosphine-P atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/35—Ketones, e.g. benzophenone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
- B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
- B01J31/18—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes containing nitrogen, phosphorus, arsenic or antimony as complexing atoms, e.g. in pyridine ligands, or in resonance therewith, e.g. in isocyanide ligands C=N-R or as complexed central atoms
- B01J31/1845—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes containing nitrogen, phosphorus, arsenic or antimony as complexing atoms, e.g. in pyridine ligands, or in resonance therewith, e.g. in isocyanide ligands C=N-R or as complexed central atoms the ligands containing phosphorus
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
- B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
- B01J31/24—Phosphines, i.e. phosphorus bonded to only carbon atoms, or to both carbon and hydrogen atoms, including e.g. sp2-hybridised phosphorus compounds such as phosphabenzene, phosphole or anionic phospholide ligands
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
- B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
- B01J31/24—Phosphines, i.e. phosphorus bonded to only carbon atoms, or to both carbon and hydrogen atoms, including e.g. sp2-hybridised phosphorus compounds such as phosphabenzene, phosphole or anionic phospholide ligands
- B01J31/2404—Cyclic ligands, including e.g. non-condensed polycyclic ligands, the phosphine-P atom being a ring member or a substituent on the ring
- B01J31/2409—Cyclic ligands, including e.g. non-condensed polycyclic ligands, the phosphine-P atom being a ring member or a substituent on the ring with more than one complexing phosphine-P atom
- B01J31/2414—Cyclic ligands, including e.g. non-condensed polycyclic ligands, the phosphine-P atom being a ring member or a substituent on the ring with more than one complexing phosphine-P atom comprising aliphatic or saturated rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2231/00—Catalytic reactions performed with catalysts classified in B01J31/00
- B01J2231/40—Substitution reactions at carbon centres, e.g. C-C or C-X, i.e. carbon-hetero atom, cross-coupling, C-H activation or ring-opening reactions
- B01J2231/42—Catalytic cross-coupling, i.e. connection of previously not connected C-atoms or C- and X-atoms without rearrangement
- B01J2231/4205—C-C cross-coupling, e.g. metal catalyzed or Friedel-Crafts type
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
- B01J2531/80—Complexes comprising metals of Group VIII as the central metal
- B01J2531/82—Metals of the platinum group
- B01J2531/824—Palladium
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Materials Engineering (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Catalysts (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
LA INVENCION SE REFIERE A UN PROCESO PARA LA ELABORACION DE DERIVADOS 4 - ACIDO CINAMICO METILIDENO SUSTITUIDOS DE LA FORMULA (I) DONDE R ES CN O COR{SUP,1}, DONDE R{SUP,1} SIGNIFICA OH, O - C{SUB,6} - C{SUB,10} - ARILO, O - C{SUB,1} - C{SUB,20} - ALQUILO, NH{SUB,2}, NH - C{SUB,6} - C{SUB,10} - ARILO, NH C{SUB,1} - C{SUB,20} - ALQUILO, N - C{SUB,1} - C{SUB,20} - ALQUILO - C{SUB,6} C{SUB,10} - ARILO O N - DI - C{SUB,1} - C{SUB,20} - ALQUILO, R'' ES H, C{SUB,1} - C{SUB,20} - ALQUILO O R, R'''' ES H, C{SUB,1} - C{SUB,20} - ALQUILO, C{SUB,6} - C{SUB,20} - ARILO O UN RESTO DE LA FORMULA Y Z ES UN RESTO ELEGIDO A PARTIR DE LAS FORMULA II, III Y IV DONDE R{SUP,1} SIGNIFICA H O METILO, DONDE SE TRANSFORMA UN HALOGENURO ARILO DE LA FORMULA (V), DONDE Z POSEE EL SIGNIFICADO DADO, Y X{SUP,1} SIGNIFICA CL, BR O YODO, CON UN DERIVADO DE ACIDO ACRILICO DE LA FORMULA (VI) DONDE R, R'' Y R'''' POSEEN LOS SIGNIFICADOS DADOS, EN PRESENCIA DE CATALIZADORES DE PALADIO. LA INVENCION SE REFIERE ADEMAS A NUEVOS COMPUESTOS DE LA FORMULA I, CONDE Z ES UN RESTO DE LAS FORMULAS III O IV.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4424489A DE4424489A1 (de) | 1994-07-12 | 1994-07-12 | Verfahren zur Herstellung von substituierten 4-Methyliden-Zimtsäure-Derivaten |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2147808T3 true ES2147808T3 (es) | 2000-10-01 |
Family
ID=6522903
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES95110193T Expired - Lifetime ES2147808T3 (es) | 1994-07-12 | 1995-06-30 | Procedimiento para la obtencion de derivados de acido 4-metiliden-cinamico, asi como nuevos derivados de acido metilidencinamico. |
Country Status (4)
Country | Link |
---|---|
US (1) | US5639883A (es) |
EP (1) | EP0696568B1 (es) |
DE (2) | DE4424489A1 (es) |
ES (1) | ES2147808T3 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997033855A1 (de) * | 1996-03-13 | 1997-09-18 | Basf Aktiengesellschaft | Cinnamylidencampherderivate und ihre verwendung als uv-a lichtschutzmittel |
DE19701448A1 (de) * | 1997-01-17 | 1998-07-23 | Basf Ag | Arylaminomethylencampherderivate |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3560510A (en) * | 1969-03-05 | 1971-02-02 | Aldrich Chem Co Inc | 2-benzhydrylquinuclidines |
CH654286A5 (de) * | 1981-11-04 | 1986-02-14 | Ciba Geigy Ag | Verfahren zur pd-katalysierten arylierung von olefinen mit arylhalogeniden. |
FR2528420A1 (fr) * | 1982-06-15 | 1983-12-16 | Oreal | Nouveaux 3-benzylidene camphres, leur procede de preparation et leur utilisation pour la protection contre les rayons uv |
EP0103544A1 (de) * | 1982-09-08 | 1984-03-21 | Ciba-Geigy Ag | Verfahren zur Pd-katalysierten Arylierung von Olefinen mit Arylchloriden |
LU85139A1 (fr) * | 1983-12-14 | 1985-09-12 | Oreal | Nouveaux derives du 3-benzylidene camphre,leur procede de preparation et leur utilisation en tant qu'agents de protection contre les rayons uv et en tant que medicaments |
LU85138A1 (fr) * | 1983-12-14 | 1985-09-12 | Oreal | Compositions pharmaceutiques contenant des derives de l'acide campho-methylidene cinnamique |
DE4204922A1 (de) * | 1992-02-19 | 1993-08-26 | Merck Patent Gmbh | Ketotricyclo(5.2.1.0)decan-derivate |
-
1994
- 1994-07-12 DE DE4424489A patent/DE4424489A1/de not_active Withdrawn
-
1995
- 1995-06-06 US US08/487,093 patent/US5639883A/en not_active Expired - Fee Related
- 1995-06-30 EP EP95110193A patent/EP0696568B1/de not_active Expired - Lifetime
- 1995-06-30 DE DE59508302T patent/DE59508302D1/de not_active Expired - Fee Related
- 1995-06-30 ES ES95110193T patent/ES2147808T3/es not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DE4424489A1 (de) | 1996-01-18 |
US5639883A (en) | 1997-06-17 |
EP0696568B1 (de) | 2000-05-10 |
DE59508302D1 (de) | 2000-06-15 |
EP0696568A1 (de) | 1996-02-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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