ES2146239T3 - Procedimiento de preparacion de compuestos 2-ciano-4-oxo-4h-benzopiranicos. - Google Patents

Procedimiento de preparacion de compuestos 2-ciano-4-oxo-4h-benzopiranicos.

Info

Publication number
ES2146239T3
ES2146239T3 ES94110888T ES94110888T ES2146239T3 ES 2146239 T3 ES2146239 T3 ES 2146239T3 ES 94110888 T ES94110888 T ES 94110888T ES 94110888 T ES94110888 T ES 94110888T ES 2146239 T3 ES2146239 T3 ES 2146239T3
Authority
ES
Spain
Prior art keywords
alkyl
chem
phenyl
general formula
oxo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94110888T
Other languages
English (en)
Inventor
Takayuki Higashii
Hideki Ushio
Yukari Fujimoto
Tsutomu Matsumoto
Masayoshi Minai
Katsuichi Yasunaga
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP17333393A external-priority patent/JP3269188B2/ja
Priority claimed from JP17443993A external-priority patent/JP3185482B2/ja
Priority claimed from JP17806593A external-priority patent/JP3362458B2/ja
Priority claimed from JP18025093A external-priority patent/JP3528204B2/ja
Priority claimed from JP20749893A external-priority patent/JP3486922B2/ja
Priority claimed from JP27366993A external-priority patent/JP3355535B2/ja
Application filed by Sumitomo Chemical Co Ltd filed Critical Sumitomo Chemical Co Ltd
Application granted granted Critical
Publication of ES2146239T3 publication Critical patent/ES2146239T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/24—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

SE PRESENTA UN PROCESO PARA PRODUCCION DE COMPUESTOS DE 2-CIANO-4OXO-4H-BENZOPIRAN CON LA FORMULA (2), DONDE R1 Y R2 SON INDEPENDIENTEMENTE HIDROGENO, HALOGENO, HIDROXI, ALQUILO C1-C5, ALCOXI C1-C5, NITRO O UN GRUPO DE RCONH DONDE R ES ALQUILO C1-C20, FENILO, ALQUILO(C1-C20) FENIL-SUSTITUIDO, FENIL(C1-C20)ALCOXIFENILO O (C1-C20)ALCOXIFENILO. ESTE PROCESO DE PRODUCCION SE CARACTERIZA PORQUE UNA CARBOXAMIDA DE FORMULA GENERAL (1), DONDE R1 Y R2 SON COMO SE HA DEFINIDO ANTERIORMENTE, REACCIONA CON UN AGENTE DESHIDRATANTE EN PRESENCIA DE UN COMPUESTO DE PIRIDINA CON LA FORMULA GENERAL (4), DONDE A1 Y A2 SON INDEPENDIENTEMENTE HIDROGENO O ALQUILO C1-C5. SI EL PRODUCTO FINAL NO PUEDE OBTENERSE EN CRISTALES CON BUENAS PROPIEDADES DE FILTRACION CON TRATAMIENTOS ORDINARIOS, UNA NUEVA TECNICA COMO LA AQUI DESCRITA PUEDE PROPORCIONAR TALES CRISTALES DISOLVIENDO EL PRODUCTO DE REACCION EN UN SOLVENTE ORGANICO INSOLUBLE O LIGERAMENTE SOLUBLE EN AGUA; VERTIENDO LA SOLUCION RESULTANTE EN AGUA; Y ELIMINANDO EL SOLVENTE ORGANICO POR DESTILACION CON AGITACION HASTA CONSEGUIR LA CRISTALIZACION DEL PRODUCTO FINAL.
ES94110888T 1993-07-13 1994-07-13 Procedimiento de preparacion de compuestos 2-ciano-4-oxo-4h-benzopiranicos. Expired - Lifetime ES2146239T3 (es)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP17333393A JP3269188B2 (ja) 1993-07-13 1993-07-13 カルボン酸誘導体の製造法
JP17443993A JP3185482B2 (ja) 1993-07-14 1993-07-14 ニトリル化方法
JP17806593A JP3362458B2 (ja) 1993-07-19 1993-07-19 芳香族アミド化合物の製造法
JP18025093A JP3528204B2 (ja) 1993-07-21 1993-07-21 ２−カルボキシ−ベンゾ−４−ピロン類の製造法
JP20749893A JP3486922B2 (ja) 1993-08-23 1993-08-23 酸アミドの製造法
JP27366993A JP3355535B2 (ja) 1993-11-01 1993-11-01 有機化合物結晶の製造方法

Publications (1)

Publication Number Publication Date
ES2146239T3 true ES2146239T3 (es) 2000-08-01

Family

ID=27553401

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94110888T Expired - Lifetime ES2146239T3 (es) 1993-07-13 1994-07-13 Procedimiento de preparacion de compuestos 2-ciano-4-oxo-4h-benzopiranicos.

Country Status (6)

Country Link
US (1) US5659051A (es)
EP (1) EP0634409B1 (es)
AT (1) ATE192148T1 (es)
CA (1) CA2127945C (es)
DE (1) DE69424095T2 (es)
ES (1) ES2146239T3 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH691301A5 (de) * 1995-06-29 2001-06-29 Sumitomo Chemical Co Verfahren zur Herstellung von 2-Acetyl-6-(4-(4-phenylbutoxy)benzoyl)aminophenol.
AU2002242058A1 (en) * 2001-02-01 2002-08-12 Ziwei Huang Synthesis of 4h-chromene derivatives
WO2002085880A1 (fr) * 2001-04-19 2002-10-31 Ono Pharmaceutical Co., Ltd. Procede de fabrication d'un compose de nitrile
AU2003211758A1 (en) 2002-02-28 2003-10-08 Ono Pharmaceutical Co., Ltd. Process for producing chromone compound
EP1739071B1 (en) * 2004-04-01 2012-06-06 Sumitomo Chemical Company, Limited Method for producing carboxylic acid compound
US20090053641A1 (en) * 2005-03-24 2009-02-26 Kazuyoshi Kuroda Charge control agent and related art
ITMI20061606A1 (it) * 2006-08-09 2008-02-10 Dipharma Spa Procedimento per la preparazione di composti nitrilici
CN105732367A (zh) * 2016-03-23 2016-07-06 叶芳 对苯丁氧基苯甲酸及其制备方法
CN110423206B (zh) * 2019-07-17 2022-07-08 天津大学 从氨肟化反应产物中分离环己酮肟、环己酮与甲苯的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1296469A (es) * 1970-02-05 1972-11-15
CA960223A (en) * 1970-02-05 1974-12-31 Mervyn E. Peel Tetrazolyl chromones
GB1428676A (en) * 1972-05-25 1976-03-17 Fisons Ltd Process for the production of bis-chromone derivatives
GB1457254A (en) * 1972-12-05 1976-12-01 Miles Lab 1-phenoxy-2-hydroxy-3-chromonyloxy-propane derivatives
GB1457256A (en) * 1972-12-05 1976-12-01 Miles Lab 1-phenoxy-2-formyloxy-3-2-cyanochromonyloxy-propanes
GB1457255A (en) * 1972-12-05 1976-12-01 Miles Lab 1-phenoxy-2-hydroxy-3-2-amido-chromonyloxy-propanes
BE794639A (en) * 1973-01-26 1973-05-16 Fisons Ltd Phenoxy-alkyloxy-4-oxo-4h-1-benzopyran-2-carboxylic - acids and-2-yl tetrazoles - anaphylactic slow reacting substance anta
GB1488707A (en) * 1974-07-10 1977-10-12 Fisons Ltd 5-(2-hydroxy-propoxy)-4-oxo-8-propyl-4h-1-benzopyran-2-carboxylic acid and derivatives thereof

Also Published As

Publication number Publication date
CA2127945C (en) 2007-01-09
CA2127945A1 (en) 1995-01-14
ATE192148T1 (de) 2000-05-15
EP0634409A1 (en) 1995-01-18
EP0634409B1 (en) 2000-04-26
US5659051A (en) 1997-08-19
DE69424095D1 (de) 2000-05-31
DE69424095T2 (de) 2000-09-28

Similar Documents

Publication Publication Date Title
CA2269053A1 (en) Crystals of benzimidazole derivatives and their production
US4289699A (en) Process for the production of N-(hydroxyphenyl) maleimides
NO307379B1 (no) 3-merkapto-1-(1,3-tiazolin-2-yl)azetidin-derivater
ES2146239T3 (es) Procedimiento de preparacion de compuestos 2-ciano-4-oxo-4h-benzopiranicos.
US4202825A (en) Quercetin pentamethyl carbamate and a process for its preparation
US4131617A (en) Preparation of new isobutylramide derivatives
US4769456A (en) Sulfenamide derivatives and their production
US5026873A (en) Process for direct isolation of captopril
CA2200604A1 (en) Novel production intermediate and process for producing pyridine derivative
HUT45053A (en) Process for producing 7-(/meta-substituted/-phenyl-glycin-amido)-1-carba-1-detia-cefems
KR840000556A (ko) 5,6,7,7a-테트라하이드로-4H-티에노(3,2-c)-피리딘-2-온 유도체의 제조방법
Kaválek et al. Kinetics and mechanism of solvolysis of N-aryl sulfuric diamides
KR830000127B1 (ko) 시스-5-플루오로-2-메틸-1-[p-(메틸설피닐)벤질리덴]인덴-3-아세트산의 제조방법
US4028369A (en) Preparation of glycol (2-(p-chlorophenoxy)-2-methylpropionate)-2-nicotinate
KR100517343B1 (ko) 메톡시페닐하이드라진의 제조방법
CA2307979A1 (en) Novel production intermediate and process for producing pyridine derivative
SE8503811L (sv) Nytt forfarande for framstellning av en aminolakton
EP1067111A4 (en) PRODUCTION OF A HYDROQUINONE-DIESTER DERIVATIVE
HU9202666D0 (en) Method and intermediary products for production of 6-fluooro-benzisothiazoles
HUT50835A (en) Process for producing thiazolo benzimidazole derivatives
NO20034438D0 (no) Fremgangsmåte for fremstilling av et 7-kinolyl-3,5- dihydroksyhept-6-enoeat
JPS6440468A (en) Novel indenoimidazole derivative
JPS59163370A (ja) Ｏ−（アミノメチル）フエニル酢酸ラクタムの製造方法
FI911081A0 (fi) Foerfarande foer framstaellning av penem-foereningar.
JPS55151547A (en) Production of guanidinocapronic ester

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 634409

Country of ref document: ES