ES2145598T3 - Procedimiento para la sintesis electroquimica de n-acetilcisteina a partir de cistina. - Google Patents

Procedimiento para la sintesis electroquimica de n-acetilcisteina a partir de cistina.

Info

Publication number
ES2145598T3
ES2145598T3 ES97919417T ES97919417T ES2145598T3 ES 2145598 T3 ES2145598 T3 ES 2145598T3 ES 97919417 T ES97919417 T ES 97919417T ES 97919417 T ES97919417 T ES 97919417T ES 2145598 T3 ES2145598 T3 ES 2145598T3
Authority
ES
Spain
Prior art keywords
acetyl
cystine
cysteine
produce
cistina
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97919417T
Other languages
English (en)
Inventor
Riera Antonio Aldaz
Leguey Vicente Montiel
Garcia Vicente Garcia
Garcia Jose Gonzalez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universidad de Alicante
Original Assignee
Universidad de Alicante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universidad de Alicante filed Critical Universidad de Alicante
Application granted granted Critical
Publication of ES2145598T3 publication Critical patent/ES2145598T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C25ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25BELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B3/00Electrolytic production of organic compounds
    • C25B3/20Processes
    • C25B3/25Reduction
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D61/00Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/42Electrodialysis; Electro-osmosis ; Electro-ultrafiltration; Membrane capacitive deionization
    • B01D61/44Ion-selective electrodialysis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/02Preparation of thiols, sulfides, hydropolysulfides or polysulfides of thiols
    • C07C319/06Preparation of thiols, sulfides, hydropolysulfides or polysulfides of thiols from sulfides, hydropolysulfides or polysulfides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/02Preparation of thiols, sulfides, hydropolysulfides or polysulfides of thiols
    • C07C319/12Preparation of thiols, sulfides, hydropolysulfides or polysulfides of thiols by reactions not involving the formation of mercapto groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/22Preparation of thiols, sulfides, hydropolysulfides or polysulfides of hydropolysulfides or polysulfides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A20/00Water conservation; Efficient water supply; Efficient water use
    • Y02A20/124Water desalination

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Water Supply & Treatment (AREA)
  • Materials Engineering (AREA)
  • Metallurgy (AREA)
  • Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Electrochemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Electrolytic Production Of Non-Metals, Compounds, Apparatuses Therefor (AREA)

Abstract

LA INVENCION SE REFIERE A UN PROCESO QUE CONSISTE EN: (A) OBTENCION DE N - ACETIL - CISTEINA A PARTIR DE L - CISTINA, MEDIANTE LAS SIGUIENTES FASES: (I) ACETILACION DE L - CISTINA, PARA PRODUCIR N - ACETIL CISTINA; (II) ELECTRORREDUCCION Y DESALINACION MEDIANTE ELECTRODIALISIS DE LA N - ACETIL - CISTINA ASI PRODUCIDA, PARA PRODUCIR N - ACETIL CISTEINA; O (B) OBTENCION DE N - ACETIL - CISTEINA A PARTIR DE L - CISTINA, A TRAVES DE LAS SIGUIENTES FASES: (I) ACETILACION Y DESALINACION DE L CISTINA PARA PRODUCIR N ACETIL - CISTINA; (II) ELECTRORREDUCCION DE N - ACETIL - CISTINA QUE PUEDE PROCEDER O NO DE LA FASE PRECEDENTE (I), PARA PRODUCIR N - ACETIL CISTEINA; (C) OBTENCION DE N - ACETIL - CISTEINA A PARTIR DE L - CISTINA, MEDIANTE LAS SIGUIENTES FASES: (I) ELECTRORREDUCCION DE L - CISTINA PARA PRODUCIR L - CISTEINA; (II) ACETILACION Y DESALINACION MEDIANTE ELECTRODIALISIS DE L CISTEINA, QUE PUEDE PROCEDER O NO DE LA FASE PRECEDENTE (I), PARA PRODUCIR N - ACETIL - CISTEINA. LA N - ACETIL - CISTEINA ASI OBTENIDA PRESENTA IMPORTANTES UTILIZACIONES EN EL SECTOR FARMACEUTICO.
ES97919417T 1996-05-07 1997-05-07 Procedimiento para la sintesis electroquimica de n-acetilcisteina a partir de cistina. Expired - Lifetime ES2145598T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES09601014A ES2108654B1 (es) 1996-05-07 1996-05-07 Procedimiento para la sintesis electroquimica de n-acetilcisteina a partir de cistina.

Publications (1)

Publication Number Publication Date
ES2145598T3 true ES2145598T3 (es) 2000-07-01

Family

ID=8294718

Family Applications (2)

Application Number Title Priority Date Filing Date
ES09601014A Expired - Fee Related ES2108654B1 (es) 1996-05-07 1996-05-07 Procedimiento para la sintesis electroquimica de n-acetilcisteina a partir de cistina.
ES97919417T Expired - Lifetime ES2145598T3 (es) 1996-05-07 1997-05-07 Procedimiento para la sintesis electroquimica de n-acetilcisteina a partir de cistina.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES09601014A Expired - Fee Related ES2108654B1 (es) 1996-05-07 1996-05-07 Procedimiento para la sintesis electroquimica de n-acetilcisteina a partir de cistina.

Country Status (11)

Country Link
US (1) US6159352A (es)
EP (1) EP0905282B1 (es)
JP (1) JP2000509705A (es)
AT (1) ATE189273T1 (es)
AU (1) AU714021B2 (es)
CA (1) CA2253538A1 (es)
DE (1) DE69701224T2 (es)
ES (2) ES2108654B1 (es)
GR (1) GR3033038T3 (es)
PT (1) PT905282E (es)
WO (1) WO1997042358A1 (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2137105B1 (es) * 1997-03-20 2000-08-16 Dsm Deretil S A Procedimiento para la obtencion de l-cisteinas n-monosustituidas por via electroquimica.
DE19844061B4 (de) * 1998-09-25 2007-03-29 Degussa Ag Verfahren zur Herstellung von N-Alkanoylcysteinen
US6448621B1 (en) * 1999-06-04 2002-09-10 Mrinal Thakur Sensor apparatus using an electrochemical cell
US6586810B2 (en) 1999-06-04 2003-07-01 Mrinal Thakur Sensor apparatus using an electrochemical cell
DE10039171A1 (de) * 2000-08-10 2002-02-28 Consortium Elektrochem Ind Kathode für Elektrolysezellen
KR101805540B1 (ko) 2011-06-08 2017-12-07 삼성에스디아이 주식회사 리튬티타네이트의 제조방법
US11648506B2 (en) 2018-02-07 2023-05-16 Palo Alto Research Center Incorporated Electrochemical desalination system
US11117090B2 (en) 2018-11-26 2021-09-14 Palo Alto Research Center Incorporated Electrodialytic liquid desiccant dehumidifying system
US11015875B2 (en) * 2019-04-17 2021-05-25 Palo Alto Research Center Incorporated Electrochemical heat pump
CN110344077A (zh) * 2019-07-01 2019-10-18 吉林大学 一种由l-胱氨酸电化学合成n-乙酰-l半胱氨酸的方法
US12085293B2 (en) 2021-03-17 2024-09-10 Mojave Energy Systems, Inc. Staged regenerated liquid desiccant dehumidification systems
US11872528B2 (en) 2021-11-09 2024-01-16 Xerox Corporation System and method for separating solvent from a fluid
US11944934B2 (en) 2021-12-22 2024-04-02 Mojave Energy Systems, Inc. Electrochemically regenerated liquid desiccant dehumidification system using a secondary heat pump
CN115772104A (zh) * 2022-11-15 2023-03-10 广东百澳药业有限公司 一种n-乙酰-l-半胱氨酸的制备方法
WO2024129618A1 (en) 2022-12-12 2024-06-20 Mojave Energy Systems, Inc. Liquid desiccant air conditioning system and control methods

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1030259A (en) * 1964-10-29 1966-05-18 Senju Pharma Co Improvements in the production of n-acetyl-l-cysteine
JPS523021A (en) * 1975-06-24 1977-01-11 Nippon Rikagaku Yakuhin Kk Method for isolation of n-acylcysteine
FR2577242B1 (fr) * 1985-02-11 1987-10-30 Air Liquide Procede de fabrication d'amino-alcools par reduction electrochimique de nitro-alcools
JPH0745450B2 (ja) * 1986-10-29 1995-05-17 日本理化学薬品株式会社 高水溶性n−アセチルアミノ酸類の製造方法
EP0436055A1 (en) * 1990-01-04 1991-07-10 The Electrosynthesis Company, Inc. High yield methods for electrochemical preparation of cysteine and analogues
ES2032155A6 (es) * 1990-04-06 1993-01-01 Almu S A Procedimiento de obtencion de l-carboximetil-cisteina a partir de l-cisteina por metodos electroquimicos.
ES2098191B1 (es) * 1995-06-01 1997-12-16 Dsm Deretil S A Procedimiento para la obtencion de tioeteres para uso farmaceutico por metodos electroquimicos.

Also Published As

Publication number Publication date
GR3033038T3 (en) 2000-08-31
US6159352A (en) 2000-12-12
AU714021B2 (en) 1999-12-16
ES2108654A1 (es) 1997-12-16
DE69701224T2 (de) 2000-07-27
AU2389697A (en) 1997-11-26
EP0905282B1 (en) 2000-01-26
ATE189273T1 (de) 2000-02-15
PT905282E (pt) 2000-05-31
DE69701224D1 (de) 2000-03-02
CA2253538A1 (en) 1997-11-13
JP2000509705A (ja) 2000-08-02
WO1997042358A1 (es) 1997-11-13
EP0905282A1 (en) 1999-03-31
ES2108654B1 (es) 1998-07-01

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