ES2137859A1 - Procedimiento para la preparacion de los compuestos anativirales pen-ciclovir y famciclovir. - Google Patents
Procedimiento para la preparacion de los compuestos anativirales pen-ciclovir y famciclovir.Info
- Publication number
- ES2137859A1 ES2137859A1 ES009701612A ES9701612A ES2137859A1 ES 2137859 A1 ES2137859 A1 ES 2137859A1 ES 009701612 A ES009701612 A ES 009701612A ES 9701612 A ES9701612 A ES 9701612A ES 2137859 A1 ES2137859 A1 ES 2137859A1
- Authority
- ES
- Spain
- Prior art keywords
- penciclovir
- famciclovir
- purine
- preparing
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
- G06V30/00—Character recognition; Recognising digital ink; Document-oriented image-based pattern recognition
- G06V30/10—Character recognition
- G06V30/14—Image acquisition
- G06V30/142—Image acquisition using hand-held instruments; Constructional details of the instruments
- G06V30/1426—Image acquisition using hand-held instruments; Constructional details of the instruments by sensing position defining codes on a support
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Procedimiento para la preparación de los compuestos antivirales pen-ciclovir y fam-ciclovir. Un procedimiento para la preparación de pen-ciclovir o fam-ciclovir, que comprende una o más de las siguientes etapas: a) formar una purina mediante el cierre del anillo de imidazol o pirimidina; b) hacer reaccionar una purina con un intermedio precursor de cadena lateral en posición 9 adecuado; c) convertir la cadena lateral en posición 9 en 4-hidroxi-3- hidroximetilbut-l-ilo o 4-acetoxi-3-acetoximetilbut-l-ilo d) convertir una purina en guanina o 2-aminopurina
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9615253.3A GB9615253D0 (en) | 1996-07-20 | 1996-07-20 | Pharmaceuticals |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2137859A1 true ES2137859A1 (es) | 1999-12-16 |
ES2137859B1 ES2137859B1 (es) | 2000-11-16 |
Family
ID=10797218
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES009701612A Expired - Fee Related ES2137859B1 (es) | 1996-07-20 | 1997-07-18 | Procedimiento para la preparacion de los compuestos antivirales penciclovir y famciclovir. |
Country Status (5)
Country | Link |
---|---|
AT (1) | AT412212B (es) |
ES (1) | ES2137859B1 (es) |
GB (1) | GB9615253D0 (es) |
GR (1) | GR1002954B (es) |
PT (1) | PT102029B (es) |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5075445A (en) * | 1983-08-18 | 1991-12-24 | Beecham Group P.L.C. | Guanine derivatives |
WO1995028402A2 (en) * | 1994-04-19 | 1995-10-26 | Smithkline Beecham Plc | Preparation of purines |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL73682A (en) * | 1983-12-20 | 1991-08-16 | Medivir Ab | Antiviral pharmaceutical compositions containing 9-hydroxy aliphatic derivatives of guanine,some new such derivatives and process for their preparation |
EP0152316B1 (en) * | 1984-01-26 | 1989-07-26 | Merck & Co. Inc. | Substituted butyl guanines and their utilization in antiviral compositions |
EP0182024B1 (en) * | 1984-09-20 | 1991-04-03 | Beecham Group Plc | Purine derivatives and their pharmaceutical use |
SE8406538D0 (sv) * | 1984-12-21 | 1984-12-21 | Astra Laekemedel Ab | Novel derivatives of purine |
DE3671227D1 (de) * | 1985-07-27 | 1990-06-21 | Beecham Group Plc | 9-substituierte guaninmonohydrate. |
GB8817270D0 (en) * | 1988-07-20 | 1988-08-24 | Beecham Group Plc | Novel process |
GB8817607D0 (en) * | 1988-07-23 | 1988-09-01 | Beecham Group Plc | Novel process |
GB8822236D0 (en) * | 1988-09-21 | 1988-10-26 | Beecham Group Plc | Chemical process |
GB8922076D0 (en) * | 1989-09-28 | 1989-11-15 | Beecham Group Plc | Novel process |
-
1996
- 1996-07-20 GB GBGB9615253.3A patent/GB9615253D0/en active Pending
-
1997
- 1997-07-18 PT PT102029A patent/PT102029B/pt not_active IP Right Cessation
- 1997-07-18 ES ES009701612A patent/ES2137859B1/es not_active Expired - Fee Related
- 1997-07-18 AT AT0122797A patent/AT412212B/de not_active IP Right Cessation
- 1997-07-18 GR GR970100281A patent/GR1002954B/el not_active IP Right Cessation
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5075445A (en) * | 1983-08-18 | 1991-12-24 | Beecham Group P.L.C. | Guanine derivatives |
WO1995028402A2 (en) * | 1994-04-19 | 1995-10-26 | Smithkline Beecham Plc | Preparation of purines |
Non-Patent Citations (1)
Title |
---|
HARNDEN et al. Analogues of the antiviral acyclonucleosyde 9-(4-hydroxy-3-hydroxymethylbutyl)guanine. Part 4. Substitution on the 2-amino groups. J. Chem. Soc. Perkin Trans. I. (1989) (12) paginas 2207-2213. Compuesto 5; pagina 2209, columna 2, parrafo 2. * |
Also Published As
Publication number | Publication date |
---|---|
GR1002954B (el) | 1998-08-07 |
ATA122797A (de) | 2004-04-15 |
GB9615253D0 (en) | 1996-09-04 |
AT412212B (de) | 2004-11-25 |
ES2137859B1 (es) | 2000-11-16 |
PT102029A (pt) | 1998-01-30 |
MX9705482A (es) | 1998-08-30 |
GR970100281A (en) | 1998-03-31 |
PT102029B (pt) | 1999-04-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
GB2402656A (en) | Convertible wheelchair and separate lift module for connecting to and elevating the wheelchair | |
UA41287C2 (uk) | Алкоголяти металів для отримання похідних таксану | |
DK362689D0 (da) | Hidtil ukendt fremgangsmaade | |
ATE185995T1 (de) | Verfahren zur herstellung röntgenamorpher und nanokristalliner metallpulver | |
MY113056A (en) | Preparation process of ginkgolide b from ginkgolide c | |
EP0745593A3 (en) | Process of preparation of pure 4,6-dichloropyrimidine | |
ES2137859A1 (es) | Procedimiento para la preparacion de los compuestos anativirales pen-ciclovir y famciclovir. | |
JPH0768244B1 (es) | ||
HU9500364D0 (en) | Stereoselective dynthesis of nucleoside analogues using bicyclic intermediate | |
EP1114809A4 (en) | METHOD FOR PRODUCING FLUOROBENZYL DERIVATIVES | |
ES2138537A1 (es) | Procedimiento para la preparacion de los compuestos antivirales penciclovir y famciclovir. | |
EP0902019A4 (en) | METHOD FOR PRODUCING PYRIMIDINE COMPOUNDS | |
ES2138536A1 (es) | Procedimiento para la preparacion de los compuestos antivirales penciclovir y famciclovir. | |
ES2138535A1 (es) | Procedimiento para la preparacion de los compuestos antivirales penciclovir y famciclovir. | |
CA2037687A1 (en) | 7-(diphenylmethyl)oxy-9a-methoxymitosane and making and use thereof | |
CZ123495A3 (en) | Process for preparing 2-amino-4,6-dichloropyrimidine | |
ZA952287B (en) | Process for preparing (1H-tetrazol-5-yl)tetrazolo [1,5-a] quinolines and naphthyridines | |
GR3017105T3 (en) | Oasomycine, method of its preparation and its use. | |
ES2121685A1 (es) | Procedimiento para la obtencion de (+)-trans-4(4-fluorofenil)-3-hidroximetil-1-metil-piperidina. | |
AU588434B2 (en) | 3-(1H-tetrazol-5-YL)thieno-(2,3-d)-pyrimidin-4(3H)-ones | |
IT1254299B (it) | Procedimento per la produzione di energia meccanica da fonti rinnovabili e impianto per la realizzazione di detto procedimento. | |
ES8602695A1 (es) | Procedimiento de preparacion de un derivado pirimidinico | |
ES2007083A6 (es) | Procedimiento para la obtencion de la n-sulfamoil-3-(2-guanidinotiazol-4-il-metiltio)propionamidina | |
ES8505995A1 (es) | Procedimiento de obtencion del acido 1-etil-6-fluoro-1, 4-dihidro-4-oxo-7-(1-piperacinil)-3-quinolincarboxilico |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EC2A | Search report published |
Date of ref document: 19991216 Kind code of ref document: A1 Effective date: 19991216 |
|
FD2A | Announcement of lapse in spain |
Effective date: 20180807 |