MX9705482A - Farmacos. - Google Patents

Farmacos.

Info

Publication number
MX9705482A
MX9705482A MX9705482A MX9705482A MX9705482A MX 9705482 A MX9705482 A MX 9705482A MX 9705482 A MX9705482 A MX 9705482A MX 9705482 A MX9705482 A MX 9705482A MX 9705482 A MX9705482 A MX 9705482A
Authority
MX
Mexico
Prior art keywords
purine
hydrogen
hydroxy
side chain
chloro
Prior art date
Application number
MX9705482A
Other languages
English (en)
Other versions
MXPA97005482A (es
Inventor
Victor Witold Jacewicz
David Alan Jones
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of MX9705482A publication Critical patent/MX9705482A/es
Publication of MXPA97005482A publication Critical patent/MXPA97005482A/es

Links

Classifications

    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V30/00—Character recognition; Recognising digital ink; Document-oriented image-based pattern recognition
    • G06V30/10—Character recognition
    • G06V30/14—Image acquisition
    • G06V30/142—Image acquisition using hand-held instruments; Constructional details of the instruments
    • G06V30/1426—Image acquisition using hand-held instruments; Constructional details of the instruments by sensing position defining codes on a support

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Un proceso para la preparacion de: i) "penciclovir" o ii) "famciclovir" cuyo proceso comprende uno o más de los siguientes pasos: a) formar una purina por cierre de anillo de imidazol o pirimidina; b) hacer reaccionar una purina con un intermediario de precursor de cadena lateral en la posicion 9 apropiada; c) conversion de una cadena lateral en la posicion 9 a: i) 4-hidroxi-3-hidroximetilbut-ilo o ii) 4-acetoxi-3-acetoximetilbut-1-ilo d) conversion de una purina a: i) guanina o ii) 2-aminopurina; caracterizado porque: la purina tiene la formula (I): en donde R1 es halo, hidroxi, o un grupo de sulfonato; R2 es una cadena lateral en la posicion 9; X2 es hidrogeno o hidroxi o una porcion convertible a hidrogeno o hidroxi; X2 es hidrogeno o un grupo convertible al mismo; que se convierte a "famciclovir" o "peciclovir" porque: R1 es halo, hidroxi o sulfonato se convierte a R1 y es amino.
MXPA/A/1997/005482A 1996-07-20 1997-07-18 Procedimiento para preparar penciclovir o famciclovir MXPA97005482A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9615253.3A GB9615253D0 (en) 1996-07-20 1996-07-20 Pharmaceuticals
GB9615253.3 1996-07-20

Publications (2)

Publication Number Publication Date
MX9705482A true MX9705482A (es) 1998-08-30
MXPA97005482A MXPA97005482A (es) 1998-11-12

Family

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Also Published As

Publication number Publication date
AT412212B (de) 2004-11-25
ES2137859B1 (es) 2000-11-16
ATA122797A (de) 2004-04-15
GB9615253D0 (en) 1996-09-04
ES2137859A1 (es) 1999-12-16
PT102029A (pt) 1998-01-30
GR1002954B (el) 1998-08-07
PT102029B (pt) 1999-04-30
GR970100281A (en) 1998-03-31

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Legal Events

Date Code Title Description
GB Transfer or rights

Owner name: NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD.

FG Grant or registration
MM Annulment or lapse due to non-payment of fees