ES2134298T3 - Procedimiento y dispositivo para la dosificacion de liquidos. - Google Patents

Procedimiento y dispositivo para la dosificacion de liquidos.

Info

Publication number
ES2134298T3
ES2134298T3 ES94113751T ES94113751T ES2134298T3 ES 2134298 T3 ES2134298 T3 ES 2134298T3 ES 94113751 T ES94113751 T ES 94113751T ES 94113751 T ES94113751 T ES 94113751T ES 2134298 T3 ES2134298 T3 ES 2134298T3
Authority
ES
Spain
Prior art keywords
transfer element
liquid
liquids
volume
dispensing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94113751T
Other languages
English (en)
Inventor
Friedemann Dr Krause
Sigmar Dr Klose
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Roche Diagnostics GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics GmbH filed Critical Roche Diagnostics GmbH
Application granted granted Critical
Publication of ES2134298T3 publication Critical patent/ES2134298T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0241—Drop counters; Drop formers
    • B01L3/0244—Drop counters; Drop formers using pins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F1/00—Measuring the volume flow or mass flow of fluid or fluent solid material wherein the fluid passes through a meter in a continuous flow
    • G01F1/66—Measuring the volume flow or mass flow of fluid or fluent solid material wherein the fluid passes through a meter in a continuous flow by measuring frequency, phase shift or propagation time of electromagnetic or other waves, e.g. using ultrasonic flowmeters
    • G01F1/661—Measuring the volume flow or mass flow of fluid or fluent solid material wherein the fluid passes through a meter in a continuous flow by measuring frequency, phase shift or propagation time of electromagnetic or other waves, e.g. using ultrasonic flowmeters using light
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F22/00—Methods or apparatus for measuring volume of fluids or fluent solid material, not otherwise provided for
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F3/00—Measuring the volume flow of fluids or fluent solid material wherein the fluid passes through the meter in successive and more or less isolated quantities, the meter being driven by the flow
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027—General features of the devices
    • G01N2035/1034—Transferring microquantities of liquid
    • G01N2035/1037—Using surface tension, e.g. pins or wires
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575—Volumetric liquid transfer

Landscapes

  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Electromagnetism (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Length Measuring Devices By Optical Means (AREA)
  • Image Processing (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A UN PROCEDIMIENTO Y UN DISPOSITIVO PARA LA DOSIFICACION DE LIQUIDOS, DONDE EL VOLUMEN DE UNA GOTA (14) DE PRUEBA SE DETERMINA A TRAVES DE UN DIMENSIONADO OPTICO. EL LIQUIDO (14) A SER DOSIFICADO SE APLICA EN CONTACTO CON UN ELEMENTO (15) DE TRANSFERENCIA, DE TAL MODO QUE UNA GOTA (14) SE ADHIERE AL ELEMENTO (15) DE TRANSFERENCIA. EL ELEMENTO (15) DE TRANSFERENCIA Y EL LIQUIDO ADHERIDO SE ILUMINAN EN UNA O MULTIPLES DIRECCIONES (12,13) Y LA IMAGEN RESULTANTE SE CONFIGURA SOBRE UN SENSOR (17) OPTICO. BASADO EN LA IMAGEN SE DETERMINA EL VOLUMEN DEL LIQUIDO. UNA DOSIFICACION SE CONSIGUE A TRAVES DE LA TRANSFORMACION DEL VOLUMEN (14) DE LIQUIDO ADHERIDO EN EL ELEMENTO (15) DE TRANSFERENCIA EN UN RECIPIENTE DE ANALISIS.
ES94113751T 1993-09-08 1994-09-02 Procedimiento y dispositivo para la dosificacion de liquidos. Expired - Lifetime ES2134298T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4330412A DE4330412A1 (de) 1993-09-08 1993-09-08 Verfahren und Vorrichtung zur Dosierung von Flüssigkeiten

Publications (1)

Publication Number Publication Date
ES2134298T3 true ES2134298T3 (es) 1999-10-01

Family

ID=6497167

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94113751T Expired - Lifetime ES2134298T3 (es) 1993-09-08 1994-09-02 Procedimiento y dispositivo para la dosificacion de liquidos.

Country Status (6)

Country Link
US (1) US5856200A (es)
EP (1) EP0641599B1 (es)
JP (1) JP2672264B2 (es)
AT (1) ATE180184T1 (es)
DE (2) DE4330412A1 (es)
ES (1) ES2134298T3 (es)

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DE19605006C1 (de) * 1996-01-30 1997-08-21 Foerderung Angewandter Informa Verfahren und Vorrichtung zur Detektion und Bestimmung des Volumens von in Gefäßen eingebrachten Flüssigkeiten
US6112588A (en) * 1996-10-25 2000-09-05 Speedline Technologies, Inc. Method and apparatus for measuring the size of drops of a viscous material dispensed from a dispensing system
FR2764705A1 (fr) * 1997-06-17 1998-12-18 Corning Costar Corp Procede et appareil de transfert et de distribution de petits volumes de liquide
US6051190A (en) * 1997-06-17 2000-04-18 Corning Incorporated Method and apparatus for transferring and dispensing small volumes of liquid and method for making the apparatus
US6309600B1 (en) 1997-08-28 2001-10-30 Biotrove, Inc. Apparatus for droplet microchemistry
DE19754459A1 (de) * 1997-12-08 1999-06-17 Max Planck Gesellschaft Vorrichtung und Verfahren zur Bildaufnahme an tropfenerzeugenden Dispensierköpfen
US6159186A (en) * 1998-03-13 2000-12-12 Wft Projects (Proprietary) Limited Infusion delivery system
GB9824202D0 (en) 1998-11-04 1998-12-30 Moore David F Liquid transfer system
US6473190B1 (en) * 2000-03-13 2002-10-29 Bayer Corporation Optical volume sensor
US6579724B2 (en) * 2001-09-13 2003-06-17 First Ten Angstroms Dispensing method and apparatus for dispensing very small quantities of fluid
EP1332793A1 (de) * 2002-02-04 2003-08-06 Pet International Trading Gmbh Verfahren und Vorrichtung zur Dosierung von Partikeln
DE10215270B4 (de) * 2002-04-06 2007-04-19 Robert Bosch Gmbh Verfahren zur Messung eines Meniskusvolumens oder einer Meniskushöhe eines Flüssigkeitströpfchens
DE10232852A1 (de) * 2002-07-19 2004-02-12 Abb Patent Gmbh Verfahren und Vorrichtung zur Bestimmung einer Flüssigkeitsmenge
DE10315223B3 (de) * 2003-03-31 2005-02-10 Minebea Co., Ltd. Verfahren und Vorrichtung zur Befüllung des Lagerspalts eines hydrodynamischen Lagers mit einem Schmiermittel
US7344002B2 (en) 2003-03-31 2008-03-18 Minebea Co., Ltd. Method and apparatus for filling the bearing gap of a hydrodynamic bearing with a lubricant
DE10350716B3 (de) * 2003-10-30 2005-07-14 Minebea Co., Ltd. Verfahren zur Messung des Füllstandes einer Flüssigkeit in einem Hohlraum mit sub-mm breiter Öffnung
WO2005069964A2 (en) * 2004-01-23 2005-08-04 Sri International Apparatus and method of moving micro-droplets using laser-induced thermal gradients
US7582858B2 (en) * 2004-01-23 2009-09-01 Sri International Apparatus and method of moving micro-droplets using laser-induced thermal gradients
US20060002594A1 (en) * 2004-06-09 2006-01-05 Clarke Allan J Method for producing a pharmaceutical product
US8101244B2 (en) * 2004-06-09 2012-01-24 Smithkline Beecham Corporation Apparatus and method for producing or processing a product or sample
TWI547431B (zh) * 2004-06-09 2016-09-01 史密斯克萊美占公司 生產藥物之裝置及方法
WO2009104398A1 (ja) * 2008-02-22 2009-08-27 武蔵エンジニアリング株式会社 吐出量補正方法および塗布装置
EP2133668A1 (de) * 2008-06-12 2009-12-16 CSL Behring GmbH Zerstörungsfreie Messung des Füllvolumens eines mit einer Flüssigkeit gefüllten Behälters
KR101525800B1 (ko) * 2008-07-25 2015-06-10 삼성디스플레이 주식회사 잉크젯 프린팅 시스템 및 이를 이용한 표시 장치의 제조방법
US20100229911A1 (en) 2008-12-19 2010-09-16 Hi-Z Technology Inc. High temperature, high efficiency thermoelectric module
CN102425993B (zh) * 2011-09-20 2013-04-10 北京航空航天大学 水滴流场离散截面水滴平均直径变化曲线测量方法及装置
DE102011117323B4 (de) * 2011-10-28 2013-12-19 Torsten Matthias Verfahren und Vorrichtung zur Kontrolle des Volumens mindestens einer Probe
DE102011117310B4 (de) * 2011-10-28 2013-12-19 Torsten Matthias Vorrichtung und Verfahren zur Kontrolle eines Volumens einer Probe
CN102494622B (zh) * 2011-12-09 2013-07-24 北京航空航天大学 一种水滴直径测量方法
JP5483134B2 (ja) * 2012-10-09 2014-05-07 独立行政法人産業技術総合研究所 微量液滴の体積測定方法及び装置
CN103148905A (zh) * 2013-02-03 2013-06-12 浙江大学 基于管道出口液滴图像识别的微流量检测方法
WO2016013102A1 (ja) * 2014-07-25 2016-01-28 ギガフォトン株式会社 極端紫外光生成装置
EP3657139A1 (en) * 2014-11-24 2020-05-27 ART Healthcare Ltd. Drop and drip measurement
WO2017021971A1 (en) 2015-08-05 2017-02-09 Art Healthcare Ltd. Point of care urine analyzer
WO2018081617A2 (en) 2016-10-28 2018-05-03 Beckman Coulter, Inc. Substance preparation evaluation system
US10625254B2 (en) 2017-11-22 2020-04-21 Brand Gmbh + Co Kg Method for controlling a pipetting device
DE102018130493A1 (de) * 2018-11-30 2020-06-04 Hamilton Bonaduz Ag Verfahren zum Bestimmen des Volumens einer Flüssigkeit
CN111151314B (zh) * 2020-01-15 2021-07-27 杭州电子科技大学 一种仿蚂蚁口器功能结构的微液滴制备装置及方法

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US4041995A (en) * 1975-01-30 1977-08-16 Eastman Kodak Company Gas pressure-activated drop dispenser
US4345028A (en) * 1979-01-22 1982-08-17 Minnesota Mining And Manufacturing Company Bacteria growing device
US4328801A (en) * 1980-10-30 1982-05-11 Alvin J. Marx Automated intravenous fluid regulating and administering apparatus
GB2092758B (en) * 1981-02-06 1984-10-24 Nat Iranian Oil Co Process and apparatus for determining the characteristics of a drop of a liquid required for calculating the surface tension of the liquid
US4441532A (en) * 1982-05-03 1984-04-10 The United States Of America As Represented By The Secretary Of The Army Apparatus and method for generating single droplets
JPS59135306A (ja) * 1983-01-25 1984-08-03 Toray Ind Inc 加工糸の見掛け外径測定方式
JPS61231461A (ja) * 1985-04-05 1986-10-15 Fuji Photo Film Co Ltd 試料液点着装置
US4678337A (en) * 1985-05-03 1987-07-07 Laser Metric Systems, Inc. Laser based gaging system and method of using same
DE3607244A1 (de) * 1986-03-05 1987-09-10 Bat Cigarettenfab Gmbh Vorrichtung zur erfassung der laengskanten eines stabfoermigen objekts
US5200051A (en) * 1988-11-14 1993-04-06 I-Stat Corporation Wholly microfabricated biosensors and process for the manufacture and use thereof
JPH0545354A (ja) * 1991-08-16 1993-02-23 Fuji Photo Film Co Ltd 液滴モニタ装置
US5278626A (en) * 1991-09-05 1994-01-11 Amherst Process Instruments, Inc. Non-volatile residue system for monitoring impurities in a liquid
GB2259568A (en) * 1991-09-07 1993-03-17 Emhart Inc Monitoring fluid dispensing nozzle
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DE4430757A1 (de) * 1994-08-30 1996-03-07 Boehringer Mannheim Gmbh Neue 4-Aminopyridazine, Verfahren zu ihrer Herstellung sowie diese Verbindungen enthaltende Arzneimittel

Also Published As

Publication number Publication date
ATE180184T1 (de) 1999-06-15
US5856200A (en) 1999-01-05
DE59408272D1 (de) 1999-06-24
JP2672264B2 (ja) 1997-11-05
JPH07103799A (ja) 1995-04-18
EP0641599B1 (de) 1999-05-19
EP0641599A1 (de) 1995-03-08
DE4330412A1 (de) 1995-03-09

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