ES2133136A1 - Nuevo carbonato basico de aluminio y magnesio. - Google Patents

Nuevo carbonato basico de aluminio y magnesio.

Info

Publication number
ES2133136A1
ES2133136A1 ES09702717A ES9702717A ES2133136A1 ES 2133136 A1 ES2133136 A1 ES 2133136A1 ES 09702717 A ES09702717 A ES 09702717A ES 9702717 A ES9702717 A ES 9702717A ES 2133136 A1 ES2133136 A1 ES 2133136A1
Authority
ES
Spain
Prior art keywords
whose
magnesium carbonate
preparation
pharmaceutical composition
angstrom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES09702717A
Other languages
English (en)
Other versions
ES2133136B1 (es
Inventor
Ambros Rafael Foguet
Ribera Santiago Gubert
Munoz Aurelio Sacristan
Barenys Josep Maria Castello
Hernandez Jose A Ortiz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ferrer Internacional SA
Original Assignee
Ferrer Internacional SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferrer Internacional SA filed Critical Ferrer Internacional SA
Priority to ES009702717A priority Critical patent/ES2133136B1/es
Priority to ZA9811216A priority patent/ZA9811216B/xx
Priority to PA19988464401A priority patent/PA8464401A1/es
Priority to EP98966416A priority patent/EP0968133A1/en
Priority to RU99120777/12A priority patent/RU2168464C1/ru
Priority to PCT/EP1998/008498 priority patent/WO1999035088A1/en
Priority to JP53563199A priority patent/JP2001516328A/ja
Priority to CA002282361A priority patent/CA2282361A1/en
Priority to ARP980106727A priority patent/AR007232A1/es
Priority to IL13157398A priority patent/IL131573A0/xx
Priority to BR9807275-7A priority patent/BR9807275A/pt
Priority to KR1019997007914A priority patent/KR20000075839A/ko
Priority to PL98335464A priority patent/PL335464A1/xx
Priority to AU22767/99A priority patent/AU742544B2/en
Publication of ES2133136A1 publication Critical patent/ES2133136A1/es
Priority to NO994160A priority patent/NO994160L/no
Application granted granted Critical
Publication of ES2133136B1 publication Critical patent/ES2133136B1/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01F—COMPOUNDS OF THE METALS BERYLLIUM, MAGNESIUM, ALUMINIUM, CALCIUM, STRONTIUM, BARIUM, RADIUM, THORIUM, OR OF THE RARE-EARTH METALS
    • C01F7/00—Compounds of aluminium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/10—Carbonates; Bicarbonates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01F—COMPOUNDS OF THE METALS BERYLLIUM, MAGNESIUM, ALUMINIUM, CALCIUM, STRONTIUM, BARIUM, RADIUM, THORIUM, OR OF THE RARE-EARTH METALS
    • C01F7/00—Compounds of aluminium
    • C01F7/78—Compounds containing aluminium, with or without oxygen or hydrogen, and containing two or more other elements
    • C01F7/784—Layered double hydroxide, e.g. comprising nitrate, sulfate or carbonate ions as intercalating anions
    • C01F7/785—Hydrotalcite
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2002/00—Crystal-structural characteristics
    • C01P2002/70—Crystal-structural characteristics defined by measured X-ray, neutron or electron diffraction data
    • C01P2002/72—Crystal-structural characteristics defined by measured X-ray, neutron or electron diffraction data by d-values or two theta-values, e.g. as X-ray diagram
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2002/00—Crystal-structural characteristics
    • C01P2002/70—Crystal-structural characteristics defined by measured X-ray, neutron or electron diffraction data
    • C01P2002/77—Crystal-structural characteristics defined by measured X-ray, neutron or electron diffraction data by unit-cell parameters, atom positions or structure diagrams
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2002/00—Crystal-structural characteristics
    • C01P2002/80—Crystal-structural characteristics defined by measured data other than those specified in group C01P2002/70
    • C01P2002/82—Crystal-structural characteristics defined by measured data other than those specified in group C01P2002/70 by IR- or Raman-data
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2002/00—Crystal-structural characteristics
    • C01P2002/80—Crystal-structural characteristics defined by measured data other than those specified in group C01P2002/70
    • C01P2002/88—Crystal-structural characteristics defined by measured data other than those specified in group C01P2002/70 by thermal analysis data, e.g. TGA, DTA, DSC
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00—Particle morphology
    • C01P2004/50—Agglomerated particles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Geology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)

Abstract

Nuevo carbonato básico de aluminio y magnesio. Consiste en el nuevo carbonato básico de aluminio y magnesio de fórmula Al sub,2 Mg sub,4 (OH) sub,12 CO sub,3 .3H sub,2 O (I) y cristalización romboédrica, cuyos parámetros reticulares son a=b=3,046 Ao ; c=22,79 Ao ; a = b =90º; y =120º y volumen de la celda = 183 Ao sup,3 , cuyo espectro de difracción de rayos X presenta los valores d( Ao ) siguientes: 7,597; 3,798; 2,6202; 2,5698; 2,5322; 2,2830; 1,93545; 1,72447; 1,62930; 1,52289; 1,49318; 1,46002; 1,41351; 1,38528 y 1,31011; cuyo espectro de infrarrojo presenta bandas características a 1361, 785 y 449 cm sup,-1 (Figura 1) y cuyo DSC (Differential Scanning Calorimetry) se representa en la Figura 2. Se emplea en Terapéutica como antiácido y gastroprotector.
ES009702717A 1997-12-30 1997-12-30 Nuevo carbonato basico de aluminio y magnesio. Expired - Lifetime ES2133136B1 (es)

Priority Applications (15)

Application Number Priority Date Filing Date Title
ES009702717A ES2133136B1 (es) 1997-12-30 1997-12-30 Nuevo carbonato basico de aluminio y magnesio.
ZA9811216A ZA9811216B (en) 1997-12-30 1998-12-08 Basic aluminium magnesium carbonate.
PA19988464401A PA8464401A1 (es) 1997-12-30 1998-12-10 Nuevo carbonato basico de aluminio y magnesio
PL98335464A PL335464A1 (en) 1997-12-30 1998-12-29 Basic aluminium-magnesium carbonate
PCT/EP1998/008498 WO1999035088A1 (en) 1997-12-30 1998-12-29 Basic aluminum magnesium carbonate, method for the preparation thereof and its use as a pharmaceutical composition for treating stomach acidity
JP53563199A JP2001516328A (ja) 1997-12-30 1998-12-29 塩基性炭酸マグネシウムアルミニウム、その製造方法および胃酸性度を治療するための製薬組成物としてのその使用
CA002282361A CA2282361A1 (en) 1997-12-30 1998-12-29 Basic aluminum magnesium carbonate, method for the preparation thereof and its use as a pharmaceutical composition for treating stomach acidity
ARP980106727A AR007232A1 (es) 1997-12-30 1998-12-29 Nuevo carbonato basico de aluminio y magnesio
EP98966416A EP0968133A1 (en) 1997-12-30 1998-12-29 Basic aluminium magnesium carbonate, method for the preparation thereof and its use as a pharmaceutical composition for treating stomach acidity
BR9807275-7A BR9807275A (pt) 1997-12-30 1998-12-29 Carbonato básico de alumìnio e magnésio
KR1019997007914A KR20000075839A (ko) 1997-12-30 1998-12-29 염기성 탄산 알루미늄 마그네슘, 그 제조방법 및 위산 치료를위한 약학조성물로서의 이용
RU99120777/12A RU2168464C1 (ru) 1997-12-30 1998-12-29 Основной карбонат алюминия магния, способ его получения, фармацевтическая композиция на его основе и способ лечения повышенной желудочной кислотности
AU22767/99A AU742544B2 (en) 1997-12-30 1998-12-29 Basic aluminum magnesium carbonate, method for the preparation thereof and its use as a pharmaceutical composition for treating stomach acidity
IL13157398A IL131573A0 (en) 1997-12-30 1998-12-29 Basic aluminum magnesium caronate method for the preparation thereof and its use as a pharmaceutical composition for treating stomach acidity
NO994160A NO994160L (no) 1997-12-30 1999-08-27 Basisk aluminium-magnesiumkarbonat, fremgangsmaate for fremstilling derav og dets anvendelse som et farmasöytisk preparat for behandling av magesurhet

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES009702717A ES2133136B1 (es) 1997-12-30 1997-12-30 Nuevo carbonato basico de aluminio y magnesio.

Publications (2)

Publication Number Publication Date
ES2133136A1 true ES2133136A1 (es) 1999-08-16
ES2133136B1 ES2133136B1 (es) 2000-04-01

Family

ID=8301660

Family Applications (1)

Application Number Title Priority Date Filing Date
ES009702717A Expired - Lifetime ES2133136B1 (es) 1997-12-30 1997-12-30 Nuevo carbonato basico de aluminio y magnesio.

Country Status (15)

Country Link
EP (1) EP0968133A1 (es)
JP (1) JP2001516328A (es)
KR (1) KR20000075839A (es)
AR (1) AR007232A1 (es)
AU (1) AU742544B2 (es)
BR (1) BR9807275A (es)
CA (1) CA2282361A1 (es)
ES (1) ES2133136B1 (es)
IL (1) IL131573A0 (es)
NO (1) NO994160L (es)
PA (1) PA8464401A1 (es)
PL (1) PL335464A1 (es)
RU (1) RU2168464C1 (es)
WO (1) WO1999035088A1 (es)
ZA (1) ZA9811216B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4338470B2 (ja) * 2003-08-12 2009-10-07 日鉄鉱業株式会社 ハイドロタルサイト粒子及びその製造方法
JP5056014B2 (ja) * 2004-10-20 2012-10-24 堺化学工業株式会社 ハイドロタルサイト及び合成樹脂組成物
RU2540635C2 (ru) * 2012-11-22 2015-02-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Национальный минерально-сырьевой университет "Горный" Способ получения гидрокарбоалюминатов щелочноземельных металлов из природного магнийсодержащего сырья
CN108159072A (zh) * 2017-12-04 2018-06-15 上海裕英生物医药科技有限公司 铝镁加的制备工艺
RU2678007C1 (ru) * 2017-12-05 2019-01-22 Федеральное государственное бюджетное учреждение науки Федеральный исследовательский центр "Кольский научный центр Российской академии наук" (ФИЦ КНЦ РАН) Способ получения слоистого гидроксида магния и алюминия

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3650704A (en) * 1966-07-25 1972-03-21 Teruhiko Kumura Novel synthetic hydrotalcite and antacid comprising said synthetic hydrotalcite
US4447417A (en) * 1978-02-17 1984-05-08 Anphar S.A. Basic aluminium magnesium carbonate
US4539195A (en) * 1983-02-26 1985-09-03 Giulini Chemie Gmbh Basic magnesium aluminum hydroxycarbonate

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4904457A (en) * 1974-03-30 1990-02-27 Aluminum Company Of America Synthetic hydrotalcite
DK167146B1 (da) * 1990-09-11 1993-09-06 Topsoe Haldor As Fremgangsmaade og katalysator til fremstilling af aromatiske forbindelser
US5364828A (en) * 1992-10-21 1994-11-15 Minerals Technologies Spheroidal aggregate of platy synthetic hydrotalcite
HU221280B1 (en) * 1994-08-15 2002-09-28 Aluminum Co Of America Two powder synthesis of hydrotalcite and hydrotalcite-like compounds
DE19503522A1 (de) * 1995-02-03 1996-08-08 Rwe Dea Ag Herstellung gemischter schichtförmig aufgebauter Metallhydroxide sowie deren Metalloxide

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3650704A (en) * 1966-07-25 1972-03-21 Teruhiko Kumura Novel synthetic hydrotalcite and antacid comprising said synthetic hydrotalcite
US4447417A (en) * 1978-02-17 1984-05-08 Anphar S.A. Basic aluminium magnesium carbonate
US4539195A (en) * 1983-02-26 1985-09-03 Giulini Chemie Gmbh Basic magnesium aluminum hydroxycarbonate

Also Published As

Publication number Publication date
KR20000075839A (ko) 2000-12-26
ZA9811216B (en) 1999-07-14
IL131573A0 (en) 2001-01-28
BR9807275A (pt) 2000-05-02
JP2001516328A (ja) 2001-09-25
AU2276799A (en) 1999-07-26
AR007232A1 (es) 1999-10-27
ES2133136B1 (es) 2000-04-01
EP0968133A1 (en) 2000-01-05
CA2282361A1 (en) 1999-07-15
NO994160D0 (no) 1999-08-27
PL335464A1 (en) 2000-04-25
RU2168464C1 (ru) 2001-06-10
AU742544B2 (en) 2002-01-03
PA8464401A1 (es) 2000-09-29
NO994160L (no) 1999-08-27
WO1999035088A1 (en) 1999-07-15

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