ES2131020A1 - Derivados de benzofurano, dihidrobenzofunaro, dihidrobenzopirano y benzopirano como agentes antidepresivos. - Google Patents
Derivados de benzofurano, dihidrobenzofunaro, dihidrobenzopirano y benzopirano como agentes antidepresivos.Info
- Publication number
- ES2131020A1 ES2131020A1 ES09702114A ES9702114A ES2131020A1 ES 2131020 A1 ES2131020 A1 ES 2131020A1 ES 09702114 A ES09702114 A ES 09702114A ES 9702114 A ES9702114 A ES 9702114A ES 2131020 A1 ES2131020 A1 ES 2131020A1
- Authority
- ES
- Spain
- Prior art keywords
- dihydrobenzopyran
- dihydrobenzofuran
- benzofuran
- derivatives
- antidepressant agents
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
Se describe la actividad de determinados derivados de benzofurano, dihidrobenzofurano, dihidrobenzopirano y dibenzopirano que responden a la fórmula general como inhibidores de la recaptación de aminas biógenas tales como la noradrenalina, dopamina y serotonina y su consiguiente utilización como principios activos para la preparación de nuevos medicamentos antidepresivos. Algunos de dichos derivados manifiestan mayor especificidad como inhibidores de la recaptación de la serotonina. Algunos de los derivados descritos son nuevos en la literatura.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9702114A ES2131020B1 (es) | 1997-10-13 | 1997-10-13 | Derivados de benzofurano, dihidrobenzofunaro, dihidrobenzopirano y benzopirano como agentes antidepresivos. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9702114A ES2131020B1 (es) | 1997-10-13 | 1997-10-13 | Derivados de benzofurano, dihidrobenzofunaro, dihidrobenzopirano y benzopirano como agentes antidepresivos. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2131020A1 true ES2131020A1 (es) | 1999-07-01 |
ES2131020B1 ES2131020B1 (es) | 2000-03-01 |
Family
ID=8300843
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES9702114A Expired - Fee Related ES2131020B1 (es) | 1997-10-13 | 1997-10-13 | Derivados de benzofurano, dihidrobenzofunaro, dihidrobenzopirano y benzopirano como agentes antidepresivos. |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES2131020B1 (es) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7378552B2 (en) | 2005-06-07 | 2008-05-27 | Neurocrine Biosciences, Inc. | Monoamine re-uptake inhibitors and methods relating thereto |
WO2012150231A1 (en) * | 2011-05-04 | 2012-11-08 | F. Hoffmann-La Roche Ag | Novel benzofurane-piperidine compounds |
EP2631232A1 (en) | 2012-02-21 | 2013-08-28 | Centrum Badan Molekularnych I Makromolekularnych Pan | Halogen derivatives of benzo[b]furans useful as anti-neoplastic or anti-proliferative drugs |
WO2022215754A1 (ja) * | 2021-04-10 | 2022-10-13 | 住友ファーマ株式会社 | 二環性ピリジン誘導体 |
US12077546B2 (en) | 2021-04-10 | 2024-09-03 | Sumitomo Pharma Co., Ltd. | Bicyclic pyridine derivative |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4321270A (en) * | 1981-01-29 | 1982-03-23 | E. R. Squibb & Sons, Inc. | Substituted chromans |
FR2492378A1 (fr) * | 1980-10-20 | 1982-04-23 | Erba Farmitalia | Derives de type 6h-dibenzo(b,d) pyranne 6-substitues utiles notamment comme medicaments antiulcereux, immunomodulateurs et antiviraux et procedes de leur preparation |
WO1995009159A1 (en) * | 1993-09-28 | 1995-04-06 | Otsuka Pharmaceutical Company, Limited | Quinoxaline derivative as antidiabetic agent |
-
1997
- 1997-10-13 ES ES9702114A patent/ES2131020B1/es not_active Expired - Fee Related
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2492378A1 (fr) * | 1980-10-20 | 1982-04-23 | Erba Farmitalia | Derives de type 6h-dibenzo(b,d) pyranne 6-substitues utiles notamment comme medicaments antiulcereux, immunomodulateurs et antiviraux et procedes de leur preparation |
US4321270A (en) * | 1981-01-29 | 1982-03-23 | E. R. Squibb & Sons, Inc. | Substituted chromans |
WO1995009159A1 (en) * | 1993-09-28 | 1995-04-06 | Otsuka Pharmaceutical Company, Limited | Quinoxaline derivative as antidiabetic agent |
Non-Patent Citations (1)
Title |
---|
WRIGHT, J.B. et al., Some reactions of mannich bases derived from alpha-phenoxyacetophenone and alpha-phenoxypropiophenone, J. Org. Chem. (1960), Vol. 25, paginas 1867-1872. * |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7378552B2 (en) | 2005-06-07 | 2008-05-27 | Neurocrine Biosciences, Inc. | Monoamine re-uptake inhibitors and methods relating thereto |
WO2012150231A1 (en) * | 2011-05-04 | 2012-11-08 | F. Hoffmann-La Roche Ag | Novel benzofurane-piperidine compounds |
US8921397B2 (en) | 2011-05-04 | 2014-12-30 | Hoffmann-La Roche Inc. | Benzofurane-piperidine compounds |
EP2631232A1 (en) | 2012-02-21 | 2013-08-28 | Centrum Badan Molekularnych I Makromolekularnych Pan | Halogen derivatives of benzo[b]furans useful as anti-neoplastic or anti-proliferative drugs |
WO2022215754A1 (ja) * | 2021-04-10 | 2022-10-13 | 住友ファーマ株式会社 | 二環性ピリジン誘導体 |
US12077546B2 (en) | 2021-04-10 | 2024-09-03 | Sumitomo Pharma Co., Ltd. | Bicyclic pyridine derivative |
Also Published As
Publication number | Publication date |
---|---|
ES2131020B1 (es) | 2000-03-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EC2A | Search report published |
Date of ref document: 19990701 Kind code of ref document: A1 Effective date: 19990701 |
|
FD2A | Announcement of lapse in spain |
Effective date: 20180807 |