ES2126097T3 - Derivados de diesteres fosfonicos. - Google Patents

Derivados de diesteres fosfonicos.

Info

Publication number
ES2126097T3
ES2126097T3 ES94906377T ES94906377T ES2126097T3 ES 2126097 T3 ES2126097 T3 ES 2126097T3 ES 94906377 T ES94906377 T ES 94906377T ES 94906377 T ES94906377 T ES 94906377T ES 2126097 T3 ES2126097 T3 ES 2126097T3
Authority
ES
Spain
Prior art keywords
feniltio
treatment
lower alkyl
prevention
represent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94906377T
Other languages
English (en)
Spanish (es)
Inventor
Yasuo Shinseibiru Shoji
Yoshihiko Tsuda
Kazuhiko Tsutsumi
Yasuhide Inoue
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Otsuka Pharmaceutical Factory Inc
Original Assignee
Otsuka Pharmaceutical Co Ltd
Otsuka Pharmaceutical Factory Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co Ltd, Otsuka Pharmaceutical Factory Inc filed Critical Otsuka Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ES2126097T3 publication Critical patent/ES2126097T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6503—Five-membered rings
    • C07F9/6506—Five-membered rings having the nitrogen atoms in positions 1 and 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6536—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and sulfur atoms with or without oxygen atoms, as the only ring hetero atoms
    • C07F9/6539—Five-membered rings
    • C07F9/6541—Five-membered rings condensed with carbocyclic rings or carbocyclic ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES94906377T 1993-02-15 1994-02-10 Derivados de diesteres fosfonicos. Expired - Lifetime ES2126097T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2573293 1993-02-15

Publications (1)

Publication Number Publication Date
ES2126097T3 true ES2126097T3 (es) 1999-03-16

Family

ID=12173991

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94906377T Expired - Lifetime ES2126097T3 (es) 1993-02-15 1994-02-10 Derivados de diesteres fosfonicos.

Country Status (13)

Country Link
US (1) US5480874A (enExample)
EP (1) EP0638581B1 (enExample)
JP (1) JP2926273B2 (enExample)
KR (1) KR100296163B1 (enExample)
CN (1) CN1046733C (enExample)
AT (1) ATE174923T1 (enExample)
AU (1) AU660125B2 (enExample)
CA (1) CA2118007C (enExample)
DE (1) DE69415436T2 (enExample)
DK (1) DK0638581T3 (enExample)
ES (1) ES2126097T3 (enExample)
TW (1) TW260664B (enExample)
WO (1) WO1994018212A1 (enExample)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0882730B1 (en) * 1995-12-27 2002-10-02 Otsuka Pharmaceutical Factory, Inc. Phosphonic acid diester derivatives
DK0970095T3 (da) 1997-03-07 2004-03-08 Metabasis Therapeutics Inc Hidtil ukendte benzimidazolinhibitorer for fructose-1,6-bisphosphase
AU6452098A (en) * 1997-03-07 1998-09-22 Metabasis Therapeutics, Inc. Novel purine inhibitors of fructose-1,6-bisphosphatase
US6989379B1 (en) 1999-04-22 2006-01-24 H. Lundbick A/S Selective NPY (Y5) antagonists
US6340683B1 (en) 1999-04-22 2002-01-22 Synaptic Pharmaceutical Corporation Selective NPY (Y5) antagonists (triazines)
WO2000064880A1 (en) 1999-04-22 2000-11-02 Synaptic Pharmaceutical Corporation Selective npy (y5) antagonists
US6218408B1 (en) 1999-06-30 2001-04-17 Synaptic Pharmaceutical Corporation Selective NPY (Y5) antagonists (bicyclics)
US6222040B1 (en) 1999-06-30 2001-04-24 Synaptic Pharmaceutical Corporation Selective NPY (Y5) antagonists (tricyclics)
US6214853B1 (en) 1999-06-30 2001-04-10 Synaptic Pharmaceutical Corporation Selective NPY (Y5) antagonists (bicyclics)
US7273880B2 (en) 1999-06-30 2007-09-25 H. Lunbeck A/S Selective NPY (Y5) antagonists
US6225330B1 (en) 1999-06-30 2001-05-01 Synaptic Pharmaceutical Corporation Selective NPY (Y5) antagonists (tricyclics)
JP4445262B2 (ja) 2001-10-09 2010-04-07 アムジェン インコーポレイテッド 抗炎症剤としてのイミダゾール誘導体
JP2005509616A (ja) * 2001-10-16 2005-04-14 センジェント・セラピューティクス・インク チロシンホスファターゼに対する有機硫黄阻害剤
US7485655B2 (en) 2002-01-16 2009-02-03 University Of Virginia Patent Foundation 2-Aminothiazole allosteric enhancers of A1 adenosine receptors
EP1765332A2 (en) * 2004-06-17 2007-03-28 Cengent Therapeutics, Inc. Trisubstituted nitrogen modulators of tyrosine phosphatases
EP1786421A2 (en) * 2004-07-09 2007-05-23 Cengent Therapeutics, Inc. Oxygen/nitrogen heterocycle inhibitors of tyrosine phosphatases
CA2575339A1 (en) * 2004-08-05 2006-02-09 F. Hoffmann-La Roche Ag Substituted n-acyl-2-aminothiazoles
EP1841749A1 (en) 2004-09-02 2007-10-10 Metabasis Therapeutics, Inc. Derivatives of thiazole and thiadiazole inhibitors of tyrosine phosphatases
BRPI0516557A (pt) * 2004-10-07 2008-09-09 Boehringer Ingelheim Int pi3 cinases
TW200722432A (en) * 2005-03-25 2007-06-16 Sankyo Co Thiazole compounds
CA2608696C (en) * 2005-05-19 2014-04-08 Nissan Chemical Industries, Ltd. Thiophene compound having phosphoric ester and process for producing the same
US8779154B2 (en) * 2006-09-26 2014-07-15 Qinglin Che Fused ring compounds for inflammation and immune-related uses
DE102007012284A1 (de) 2007-03-16 2008-09-18 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue substituierte Arylsulfonylglycine, deren Herstellung und deren Verwendung als Arzneimittel
DE102007035333A1 (de) 2007-07-27 2009-01-29 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue substituierte Arylsulfonylglycine, deren Herstellung und deren Verwendung als Arzneimittel
DE102007035334A1 (de) * 2007-07-27 2009-01-29 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue substituierte Arylsulfonylglycine, deren Herstellung und deren Verwendung als Arzneimittel
DE102007042154A1 (de) 2007-09-05 2009-03-12 Boehringer Ingelheim Pharma Gmbh & Co. Kg Arylsulfonylaminomethyphosphonsäure-Derivate, deren Herstellung und deren Verwendung als Arzneimittel
CN114681454B (zh) * 2022-03-17 2024-05-07 江南大学 噻唑类化合物在制备抗sars-cov-2新型冠状病毒药物中的应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU523040B2 (en) * 1978-05-15 1982-07-08 Kanebo Limited Calcium -antagonistic composition
US4434162A (en) * 1981-02-17 1984-02-28 Kanebo, Ltd. Phosphonic acid ester, pharmaceutical compositions containing the same and method of using the same
JPH0651625B2 (ja) * 1986-12-29 1994-07-06 株式会社大塚製薬工場 高脂質血症治療剤
US4822780A (en) * 1987-07-08 1989-04-18 Otsuka Pharmaceutical Factory, Inc. Carboxamide compounds
AU606808B2 (en) * 1988-06-29 1991-02-14 Otsuka Pharmaceutical Factory, Inc. Arylcarboxamide substituted by alkylphosphonates, process for preparing the same and a pharmaceutical composition containing the same
JPH0745508B2 (ja) * 1988-06-29 1995-05-17 株式会社大塚製薬工場 カルボン酸アミド誘導体
JP2584336B2 (ja) * 1989-05-30 1997-02-26 株式会社大塚製薬工場 カルボン酸アミド誘導体
US5376665A (en) * 1992-05-21 1994-12-27 Otsuka Pharmaceutical Factory, Inc. Phosphonic diester derivatives

Also Published As

Publication number Publication date
EP0638581B1 (en) 1998-12-23
AU660125B2 (en) 1995-06-08
DE69415436T2 (de) 1999-06-02
EP0638581A1 (en) 1995-02-15
TW260664B (enExample) 1995-10-21
AU6010794A (en) 1994-08-29
EP0638581A4 (en) 1995-04-12
ATE174923T1 (de) 1999-01-15
DE69415436D1 (de) 1999-02-04
CN1102528A (zh) 1995-05-10
CN1046733C (zh) 1999-11-24
JP2926273B2 (ja) 1999-07-28
WO1994018212A1 (en) 1994-08-18
US5480874A (en) 1996-01-02
DK0638581T3 (da) 1999-08-23
CA2118007A1 (en) 1994-08-18
KR950700917A (ko) 1995-02-20
CA2118007C (en) 2003-12-02
KR100296163B1 (ko) 2001-11-05

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