ES2120903A1 - Metodo y kit para la deteccion de helicobacter pylori. - Google Patents
Metodo y kit para la deteccion de helicobacter pylori.Info
- Publication number
- ES2120903A1 ES2120903A1 ES09602383A ES9602383A ES2120903A1 ES 2120903 A1 ES2120903 A1 ES 2120903A1 ES 09602383 A ES09602383 A ES 09602383A ES 9602383 A ES9602383 A ES 9602383A ES 2120903 A1 ES2120903 A1 ES 2120903A1
- Authority
- ES
- Spain
- Prior art keywords
- carbon
- breath
- patient
- labelled
- urea
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 241000590002 Helicobacter pylori Species 0.000 title 1
- 229940037467 helicobacter pylori Drugs 0.000 title 1
- OKTJSMMVPCPJKN-OUBTZVSYSA-N Carbon-13 Chemical compound [13C] OKTJSMMVPCPJKN-OUBTZVSYSA-N 0.000 abstract 7
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 abstract 6
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 5
- 239000004202 carbamide Substances 0.000 abstract 5
- 239000007864 aqueous solution Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/58—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving urea or urease
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
- C12Q1/16—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor using radioactive material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/0004—Gaseous mixtures, e.g. polluted air
- G01N33/0009—General constructional details of gas analysers, e.g. portable test equipment
- G01N33/0027—General constructional details of gas analysers, e.g. portable test equipment concerning the detector
- G01N33/0036—General constructional details of gas analysers, e.g. portable test equipment concerning the detector specially adapted to detect a particular component
- G01N33/0055—Radionuclides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/497—Physical analysis of biological material of gaseous biological material, e.g. breath
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
- G01N2333/205—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Campylobacter (G)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/968—High energy substrates, e.g. fluorescent, chemiluminescent, radioactive
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pathology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Toxicology (AREA)
- Combustion & Propulsion (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
EL METODO SE BASA EN EL ENSAYO DEL ALIENTO CON UREA MARCADA CON CARBONO-13 Y QUE COMPRENDE: (A) ADMINISTRAR AL PACIENTE UNA SOLUCION ACUOSA DE ACIDO CITRICO CON UN PH COMPRENDIDO ENTRE 2 Y 2,5; (B) RECOGER UNA MUESTRA DEL ALIENTO DEL PACIENTE PARA DETERMINAR EL CONTENIDO BASAL DEL CARBONO-13; (C) ADMINISTRAR AL PACIENTE UNA CANTIDAD APROPIADA DE UREA MARCADA CON CARBONO-13; (D) RECOGER UNA MUESTRA DEL ALIENTO DEL PACIENTE PARA DETERMINAR EL CONTENIDO DE CARBONO-13 POSTADMINISTRACION DE LA UREA MARCADA; Y (E) ANALIZAR LAS MUESTRAS DE ALIENTO RECOGIDAS PARA DETERMINAR EL CONTENIDO EN CARBONO-13 ANTES Y DESPUES DE LA ADMINISTRACION DE UREA MARCADA CON CARBONO-13. EL KIT CONTIENE UN RECIPIENTE PARA EL ACIDO CITRICO, OTRO PARA LA UREA MARCADA CON CARBONO-13, UNOS EXETEINERS DESTINADOS A CONTENER EL ALIENTO DEL PACIENTE, Y UNOS MEDIOS PARA SOPLAR EL ALIENTO DENTRO DE LOS EXETEINERS.
Priority Applications (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES09602383A ES2120903B1 (es) | 1996-11-12 | 1996-11-12 | Metodo y kit para la deteccion de helicobacter pylori. |
JP10522201A JP2000504423A (ja) | 1996-11-12 | 1997-07-21 | ヘリコバクターピロリの検出のための方法およびキット |
ARP970103267A AR015796A1 (es) | 1996-11-12 | 1997-07-21 | Kit para la deteccion de helicobacter pylori |
EP97932840A EP0881491A1 (en) | 1996-11-12 | 1997-07-21 | METHOD AND KIT FOR DETECTING $i(HELICOBACTER PYLORI) |
TR1998/01343T TR199801343T1 (xx) | 1996-11-12 | 1997-07-21 | Helicobacter pylor�' n�n tespiti ile ilgili metod ve donan�m. |
US09/101,992 US6171811B1 (en) | 1996-11-12 | 1997-07-21 | Method and kit for detecting Helicobacter pylori |
PCT/ES1997/000184 WO1998021579A1 (es) | 1996-11-12 | 1997-07-21 | METODO Y KIT PARA LA DETECCION DE $i(HELICOBACTER PYLORI) |
AU36237/97A AU3623797A (en) | 1996-11-12 | 1997-07-21 | Method and kit for detecting (helicobacter pylori) |
CN97192764.2A CN1101546C (zh) | 1996-11-12 | 1997-07-21 | 检测幽门螺杆菌的试剂盒 |
BR9709195-2A BR9709195A (pt) | 1996-11-12 | 1997-07-21 | Método e kit para detecção de heliocobacter pylori |
CO97066023A CO4650143A1 (es) | 1996-11-12 | 1997-11-11 | Kit para deteccion de helicobacter pylori |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES09602383A ES2120903B1 (es) | 1996-11-12 | 1996-11-12 | Metodo y kit para la deteccion de helicobacter pylori. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2120903A1 true ES2120903A1 (es) | 1998-11-01 |
ES2120903B1 ES2120903B1 (es) | 1999-05-16 |
Family
ID=8296652
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES09602383A Expired - Fee Related ES2120903B1 (es) | 1996-11-12 | 1996-11-12 | Metodo y kit para la deteccion de helicobacter pylori. |
Country Status (11)
Country | Link |
---|---|
US (1) | US6171811B1 (es) |
EP (1) | EP0881491A1 (es) |
JP (1) | JP2000504423A (es) |
CN (1) | CN1101546C (es) |
AR (1) | AR015796A1 (es) |
AU (1) | AU3623797A (es) |
BR (1) | BR9709195A (es) |
CO (1) | CO4650143A1 (es) |
ES (1) | ES2120903B1 (es) |
TR (1) | TR199801343T1 (es) |
WO (1) | WO1998021579A1 (es) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX9703918A (es) | 1997-05-28 | 1998-11-30 | J Marshall M D Barry | Procedimiento para preparar un producto farmaceutico reactivo para deteccion de desorden gastrointestinal causado por bacteria en el tracto gastrointestinal superior. |
JP2002513911A (ja) * | 1998-05-06 | 2002-05-14 | アイソテクニカ、インコーポレーテッド | 糖尿病症状の診断及び血糖コントロール監視用13cグルコース呼気試験 |
US6461870B2 (en) | 1998-05-06 | 2002-10-08 | Isotechnika Inc. | 13C glucose breath test for the diagnosis of diabetic indications and monitoring glycemic control |
US6136610A (en) * | 1998-11-23 | 2000-10-24 | Praxsys Biosystems, Inc. | Method and apparatus for performing a lateral flow assay |
EP1006198A1 (en) * | 1998-12-01 | 2000-06-07 | Meretek Diagnostics | A non-invasive method for the functional assessment of infants and children with an inherited metabolic disorder |
JP4497572B2 (ja) * | 1999-02-10 | 2010-07-07 | 大塚製薬株式会社 | 13c含有尿素の製造法 |
US6656127B1 (en) | 1999-06-08 | 2003-12-02 | Oridion Breathid Ltd. | Breath test apparatus and methods |
EP1198198A4 (en) | 1999-06-08 | 2005-02-16 | Oridion Breathid Ltd | DEVICE FOR CHECKING THE CALIBRATION OF GAS ANALYZER DEVICES |
US20050171449A1 (en) * | 2000-03-21 | 2005-08-04 | Suslick Kenneth S. | Method and apparatus for detecting ammonia from exhaled breath |
US7201891B1 (en) * | 2000-05-19 | 2007-04-10 | Otsuka Pharmaceutical Co., Ltd. | Pharmaceutical preparation for the diagnosis of helicobacter pylori infection |
KR100315895B1 (ko) * | 2000-05-31 | 2001-12-12 | 강성훈 | 요소호흡 검사용의 저농축 13c 표지된 요소 조성물 |
US7033838B2 (en) * | 2001-08-09 | 2006-04-25 | Sitke Aygen | Method for the diagnosis of Helicobacter pylori infection, and a diagnostic kit for performing the method |
CN1539082A (zh) * | 2001-08-09 | 2004-10-20 | �ˡ����˶�������˹ | 诊断幽门螺旋菌的方法及实施该方法的诊断试剂盒 |
US20030036097A1 (en) * | 2001-08-17 | 2003-02-20 | Aftab Alam | Urea containing reagents for treatment of proteins |
US6998250B2 (en) | 2001-10-15 | 2006-02-14 | Donald J. McMichael | Method for detecting Helicobacter pylori |
US7008777B2 (en) * | 2001-10-15 | 2006-03-07 | Barry J. Marshall | System for the detection of urease and method for using same |
US20030073155A1 (en) * | 2001-10-15 | 2003-04-17 | Mcmichael Donald J. | Methods for performing multiple diagnostic tests |
US20030072686A1 (en) * | 2001-10-15 | 2003-04-17 | Marshall Barry J. | Systems for performing multiple diagnostic tests |
USD484988S1 (en) | 2001-12-17 | 2004-01-06 | Kimberly-Clark Worldwide, Inc. | Diagnostic test kit with specimen-handling tool |
US6783976B2 (en) | 2001-12-21 | 2004-08-31 | Kimberly-Clark Worldwide, Inc. | Carrier and specimen-handling tool for use in diagnostic testing |
US7582485B2 (en) * | 2003-10-16 | 2009-09-01 | Kimberly-Clark Worldride, Inc. | Method and device for detecting ammonia odors and helicobacter pylori urease infection |
US7413550B2 (en) | 2003-10-16 | 2008-08-19 | Kimberly-Clark Worldwide, Inc. | Visual indicating device for bad breath |
EP1685850A1 (en) * | 2005-02-01 | 2006-08-02 | Sitke Dr. Aygen | A method for the diagnosis of helicobacter pylori infection and diagnostic kit for performing the method |
US20080146956A1 (en) * | 2006-12-17 | 2008-06-19 | Campuzano German A | Method based on a breath test for the detection of pathogen microorganisms |
CN101231284B (zh) * | 2007-01-23 | 2012-09-26 | 深圳市先亚生物科技有限公司 | 诊断幽门螺杆菌感染的尿素试剂盒 |
CN101243978B (zh) * | 2008-03-31 | 2010-08-11 | 南京星芒科技咨询有限公司 | 呼吸采样器及呼吸采样方法 |
CN101887062A (zh) * | 2009-05-15 | 2010-11-17 | 艾克拜尔·热合曼 | 含有13c-尿素溶液的检测幽门螺旋杆菌试剂盒 |
CN101881763A (zh) * | 2009-10-27 | 2010-11-10 | 天津赛德生物制药有限公司 | 用于胃幽门螺旋杆菌检测的尿素呼气检测试剂盒 |
US20120226183A1 (en) * | 2010-08-30 | 2012-09-06 | Quintron Instrument Company | Evacuated air chamber |
CN104458603A (zh) * | 2013-09-23 | 2015-03-25 | 苏州青山生物科技有限公司 | 一种新型幽门螺杆菌检测方法、装置及其应用 |
US20180060551A1 (en) * | 2016-08-23 | 2018-03-01 | Lenovo (Singapore) Pte. Ltd. | Using gas chromatography for authentication, advertisements, and therapies |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4830010A (en) * | 1986-04-04 | 1989-05-16 | Marshall Barry J | Methods for the diagnosis of gastrointestinal disorders |
WO1996014091A1 (en) * | 1994-11-02 | 1996-05-17 | Diabact Ab | Diagnostic preparation for detection of helicobacter pylori |
-
1996
- 1996-11-12 ES ES09602383A patent/ES2120903B1/es not_active Expired - Fee Related
-
1997
- 1997-07-21 JP JP10522201A patent/JP2000504423A/ja active Pending
- 1997-07-21 CN CN97192764.2A patent/CN1101546C/zh not_active Expired - Fee Related
- 1997-07-21 TR TR1998/01343T patent/TR199801343T1/xx unknown
- 1997-07-21 EP EP97932840A patent/EP0881491A1/en not_active Withdrawn
- 1997-07-21 BR BR9709195-2A patent/BR9709195A/pt not_active Application Discontinuation
- 1997-07-21 WO PCT/ES1997/000184 patent/WO1998021579A1/es not_active Application Discontinuation
- 1997-07-21 AU AU36237/97A patent/AU3623797A/en not_active Abandoned
- 1997-07-21 AR ARP970103267A patent/AR015796A1/es active IP Right Grant
- 1997-07-21 US US09/101,992 patent/US6171811B1/en not_active Expired - Lifetime
- 1997-11-11 CO CO97066023A patent/CO4650143A1/es unknown
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4830010A (en) * | 1986-04-04 | 1989-05-16 | Marshall Barry J | Methods for the diagnosis of gastrointestinal disorders |
WO1996014091A1 (en) * | 1994-11-02 | 1996-05-17 | Diabact Ab | Diagnostic preparation for detection of helicobacter pylori |
Non-Patent Citations (1)
Title |
---|
LOTTERER, E. et al., "The simplified 13C-urea breath test - One point analysis for detection of Helicobacter pylori infection", 1991, Z. Gastroenterol., Vol. 29, pßginas 590-594 * todo el documento * * |
Also Published As
Publication number | Publication date |
---|---|
CN1219238A (zh) | 1999-06-09 |
WO1998021579A1 (es) | 1998-05-22 |
CO4650143A1 (es) | 1998-09-03 |
BR9709195A (pt) | 2001-01-02 |
AU3623797A (en) | 1998-06-03 |
US6171811B1 (en) | 2001-01-09 |
CN1101546C (zh) | 2003-02-12 |
EP0881491A1 (en) | 1998-12-02 |
AR015796A1 (es) | 2001-05-30 |
JP2000504423A (ja) | 2000-04-11 |
ES2120903B1 (es) | 1999-05-16 |
TR199801343T1 (xx) | 1999-02-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EC2A | Search report published |
Date of ref document: 19981101 Kind code of ref document: A1 Effective date: 19981101 |
|
FD2A | Announcement of lapse in spain |
Effective date: 20170224 |