ES2120903A1 - Metodo y kit para la deteccion de helicobacter pylori. - Google Patents

Metodo y kit para la deteccion de helicobacter pylori.

Info

Publication number
ES2120903A1
ES2120903A1 ES09602383A ES9602383A ES2120903A1 ES 2120903 A1 ES2120903 A1 ES 2120903A1 ES 09602383 A ES09602383 A ES 09602383A ES 9602383 A ES9602383 A ES 9602383A ES 2120903 A1 ES2120903 A1 ES 2120903A1
Authority
ES
Spain
Prior art keywords
carbon
breath
patient
labelled
urea
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES09602383A
Other languages
English (en)
Other versions
ES2120903B1 (es
Inventor
De Bengoa Vallejo Ana Becerro
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Isomed SL
Original Assignee
Isomed SL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to ES09602383A priority Critical patent/ES2120903B1/es
Application filed by Isomed SL filed Critical Isomed SL
Priority to PCT/ES1997/000184 priority patent/WO1998021579A1/es
Priority to AU36237/97A priority patent/AU3623797A/en
Priority to ARP970103267A priority patent/AR015796A1/es
Priority to EP97932840A priority patent/EP0881491A1/en
Priority to TR1998/01343T priority patent/TR199801343T1/xx
Priority to US09/101,992 priority patent/US6171811B1/en
Priority to BR9709195-2A priority patent/BR9709195A/pt
Priority to JP10522201A priority patent/JP2000504423A/ja
Priority to CN97192764.2A priority patent/CN1101546C/zh
Priority to CO97066023A priority patent/CO4650143A1/es
Publication of ES2120903A1 publication Critical patent/ES2120903A1/es
Application granted granted Critical
Publication of ES2120903B1 publication Critical patent/ES2120903B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/58Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving urea or urease
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • C12Q1/16Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor using radioactive material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/0004Gaseous mixtures, e.g. polluted air
    • G01N33/0009General constructional details of gas analysers, e.g. portable test equipment
    • G01N33/0027General constructional details of gas analysers, e.g. portable test equipment concerning the detector
    • G01N33/0036General constructional details of gas analysers, e.g. portable test equipment concerning the detector specially adapted to detect a particular component
    • G01N33/0055Radionuclides
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/497Physical analysis of biological material of gaseous biological material, e.g. breath
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/205Assays involving biological materials from specific organisms or of a specific nature from bacteria from Campylobacter (G)
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/968High energy substrates, e.g. fluorescent, chemiluminescent, radioactive
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/975Kit

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pathology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Combustion & Propulsion (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

EL METODO SE BASA EN EL ENSAYO DEL ALIENTO CON UREA MARCADA CON CARBONO-13 Y QUE COMPRENDE: (A) ADMINISTRAR AL PACIENTE UNA SOLUCION ACUOSA DE ACIDO CITRICO CON UN PH COMPRENDIDO ENTRE 2 Y 2,5; (B) RECOGER UNA MUESTRA DEL ALIENTO DEL PACIENTE PARA DETERMINAR EL CONTENIDO BASAL DEL CARBONO-13; (C) ADMINISTRAR AL PACIENTE UNA CANTIDAD APROPIADA DE UREA MARCADA CON CARBONO-13; (D) RECOGER UNA MUESTRA DEL ALIENTO DEL PACIENTE PARA DETERMINAR EL CONTENIDO DE CARBONO-13 POSTADMINISTRACION DE LA UREA MARCADA; Y (E) ANALIZAR LAS MUESTRAS DE ALIENTO RECOGIDAS PARA DETERMINAR EL CONTENIDO EN CARBONO-13 ANTES Y DESPUES DE LA ADMINISTRACION DE UREA MARCADA CON CARBONO-13. EL KIT CONTIENE UN RECIPIENTE PARA EL ACIDO CITRICO, OTRO PARA LA UREA MARCADA CON CARBONO-13, UNOS EXETEINERS DESTINADOS A CONTENER EL ALIENTO DEL PACIENTE, Y UNOS MEDIOS PARA SOPLAR EL ALIENTO DENTRO DE LOS EXETEINERS.
ES09602383A 1996-11-12 1996-11-12 Metodo y kit para la deteccion de helicobacter pylori. Expired - Fee Related ES2120903B1 (es)

Priority Applications (11)

Application Number Priority Date Filing Date Title
ES09602383A ES2120903B1 (es) 1996-11-12 1996-11-12 Metodo y kit para la deteccion de helicobacter pylori.
JP10522201A JP2000504423A (ja) 1996-11-12 1997-07-21 ヘリコバクターピロリの検出のための方法およびキット
ARP970103267A AR015796A1 (es) 1996-11-12 1997-07-21 Kit para la deteccion de helicobacter pylori
EP97932840A EP0881491A1 (en) 1996-11-12 1997-07-21 METHOD AND KIT FOR DETECTING $i(HELICOBACTER PYLORI)
TR1998/01343T TR199801343T1 (xx) 1996-11-12 1997-07-21 Helicobacter pylor�' n�n tespiti ile ilgili metod ve donan�m.
US09/101,992 US6171811B1 (en) 1996-11-12 1997-07-21 Method and kit for detecting Helicobacter pylori
PCT/ES1997/000184 WO1998021579A1 (es) 1996-11-12 1997-07-21 METODO Y KIT PARA LA DETECCION DE $i(HELICOBACTER PYLORI)
AU36237/97A AU3623797A (en) 1996-11-12 1997-07-21 Method and kit for detecting (helicobacter pylori)
CN97192764.2A CN1101546C (zh) 1996-11-12 1997-07-21 检测幽门螺杆菌的试剂盒
BR9709195-2A BR9709195A (pt) 1996-11-12 1997-07-21 Método e kit para detecção de heliocobacter pylori
CO97066023A CO4650143A1 (es) 1996-11-12 1997-11-11 Kit para deteccion de helicobacter pylori

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES09602383A ES2120903B1 (es) 1996-11-12 1996-11-12 Metodo y kit para la deteccion de helicobacter pylori.

Publications (2)

Publication Number Publication Date
ES2120903A1 true ES2120903A1 (es) 1998-11-01
ES2120903B1 ES2120903B1 (es) 1999-05-16

Family

ID=8296652

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09602383A Expired - Fee Related ES2120903B1 (es) 1996-11-12 1996-11-12 Metodo y kit para la deteccion de helicobacter pylori.

Country Status (11)

Country Link
US (1) US6171811B1 (es)
EP (1) EP0881491A1 (es)
JP (1) JP2000504423A (es)
CN (1) CN1101546C (es)
AR (1) AR015796A1 (es)
AU (1) AU3623797A (es)
BR (1) BR9709195A (es)
CO (1) CO4650143A1 (es)
ES (1) ES2120903B1 (es)
TR (1) TR199801343T1 (es)
WO (1) WO1998021579A1 (es)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX9703918A (es) 1997-05-28 1998-11-30 J Marshall M D Barry Procedimiento para preparar un producto farmaceutico reactivo para deteccion de desorden gastrointestinal causado por bacteria en el tracto gastrointestinal superior.
JP2002513911A (ja) * 1998-05-06 2002-05-14 アイソテクニカ、インコーポレーテッド 糖尿病症状の診断及び血糖コントロール監視用13cグルコース呼気試験
US6461870B2 (en) 1998-05-06 2002-10-08 Isotechnika Inc. 13C glucose breath test for the diagnosis of diabetic indications and monitoring glycemic control
US6136610A (en) * 1998-11-23 2000-10-24 Praxsys Biosystems, Inc. Method and apparatus for performing a lateral flow assay
EP1006198A1 (en) * 1998-12-01 2000-06-07 Meretek Diagnostics A non-invasive method for the functional assessment of infants and children with an inherited metabolic disorder
JP4497572B2 (ja) * 1999-02-10 2010-07-07 大塚製薬株式会社 13c含有尿素の製造法
US6656127B1 (en) 1999-06-08 2003-12-02 Oridion Breathid Ltd. Breath test apparatus and methods
EP1198198A4 (en) 1999-06-08 2005-02-16 Oridion Breathid Ltd DEVICE FOR CHECKING THE CALIBRATION OF GAS ANALYZER DEVICES
US20050171449A1 (en) * 2000-03-21 2005-08-04 Suslick Kenneth S. Method and apparatus for detecting ammonia from exhaled breath
US7201891B1 (en) * 2000-05-19 2007-04-10 Otsuka Pharmaceutical Co., Ltd. Pharmaceutical preparation for the diagnosis of helicobacter pylori infection
KR100315895B1 (ko) * 2000-05-31 2001-12-12 강성훈 요소호흡 검사용의 저농축 13c 표지된 요소 조성물
US7033838B2 (en) * 2001-08-09 2006-04-25 Sitke Aygen Method for the diagnosis of Helicobacter pylori infection, and a diagnostic kit for performing the method
CN1539082A (zh) * 2001-08-09 2004-10-20 �ˡ����˶�������˹ 诊断幽门螺旋菌的方法及实施该方法的诊断试剂盒
US20030036097A1 (en) * 2001-08-17 2003-02-20 Aftab Alam Urea containing reagents for treatment of proteins
US6998250B2 (en) 2001-10-15 2006-02-14 Donald J. McMichael Method for detecting Helicobacter pylori
US7008777B2 (en) * 2001-10-15 2006-03-07 Barry J. Marshall System for the detection of urease and method for using same
US20030073155A1 (en) * 2001-10-15 2003-04-17 Mcmichael Donald J. Methods for performing multiple diagnostic tests
US20030072686A1 (en) * 2001-10-15 2003-04-17 Marshall Barry J. Systems for performing multiple diagnostic tests
USD484988S1 (en) 2001-12-17 2004-01-06 Kimberly-Clark Worldwide, Inc. Diagnostic test kit with specimen-handling tool
US6783976B2 (en) 2001-12-21 2004-08-31 Kimberly-Clark Worldwide, Inc. Carrier and specimen-handling tool for use in diagnostic testing
US7582485B2 (en) * 2003-10-16 2009-09-01 Kimberly-Clark Worldride, Inc. Method and device for detecting ammonia odors and helicobacter pylori urease infection
US7413550B2 (en) 2003-10-16 2008-08-19 Kimberly-Clark Worldwide, Inc. Visual indicating device for bad breath
EP1685850A1 (en) * 2005-02-01 2006-08-02 Sitke Dr. Aygen A method for the diagnosis of helicobacter pylori infection and diagnostic kit for performing the method
US20080146956A1 (en) * 2006-12-17 2008-06-19 Campuzano German A Method based on a breath test for the detection of pathogen microorganisms
CN101231284B (zh) * 2007-01-23 2012-09-26 深圳市先亚生物科技有限公司 诊断幽门螺杆菌感染的尿素试剂盒
CN101243978B (zh) * 2008-03-31 2010-08-11 南京星芒科技咨询有限公司 呼吸采样器及呼吸采样方法
CN101887062A (zh) * 2009-05-15 2010-11-17 艾克拜尔·热合曼 含有13c-尿素溶液的检测幽门螺旋杆菌试剂盒
CN101881763A (zh) * 2009-10-27 2010-11-10 天津赛德生物制药有限公司 用于胃幽门螺旋杆菌检测的尿素呼气检测试剂盒
US20120226183A1 (en) * 2010-08-30 2012-09-06 Quintron Instrument Company Evacuated air chamber
CN104458603A (zh) * 2013-09-23 2015-03-25 苏州青山生物科技有限公司 一种新型幽门螺杆菌检测方法、装置及其应用
US20180060551A1 (en) * 2016-08-23 2018-03-01 Lenovo (Singapore) Pte. Ltd. Using gas chromatography for authentication, advertisements, and therapies

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4830010A (en) * 1986-04-04 1989-05-16 Marshall Barry J Methods for the diagnosis of gastrointestinal disorders
WO1996014091A1 (en) * 1994-11-02 1996-05-17 Diabact Ab Diagnostic preparation for detection of helicobacter pylori

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4830010A (en) * 1986-04-04 1989-05-16 Marshall Barry J Methods for the diagnosis of gastrointestinal disorders
WO1996014091A1 (en) * 1994-11-02 1996-05-17 Diabact Ab Diagnostic preparation for detection of helicobacter pylori

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
LOTTERER, E. et al., "The simplified 13C-urea breath test - One point analysis for detection of Helicobacter pylori infection", 1991, Z. Gastroenterol., Vol. 29, pßginas 590-594 * todo el documento * *

Also Published As

Publication number Publication date
CN1219238A (zh) 1999-06-09
WO1998021579A1 (es) 1998-05-22
CO4650143A1 (es) 1998-09-03
BR9709195A (pt) 2001-01-02
AU3623797A (en) 1998-06-03
US6171811B1 (en) 2001-01-09
CN1101546C (zh) 2003-02-12
EP0881491A1 (en) 1998-12-02
AR015796A1 (es) 2001-05-30
JP2000504423A (ja) 2000-04-11
ES2120903B1 (es) 1999-05-16
TR199801343T1 (xx) 1999-02-22

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