ES2118814T3 - L-tartrato de (-)-(s)-2,8-dimetil-3-metilen-1-oxa-8-azaspiro(4,5)decano. - Google Patents
L-tartrato de (-)-(s)-2,8-dimetil-3-metilen-1-oxa-8-azaspiro(4,5)decano.Info
- Publication number
- ES2118814T3 ES2118814T3 ES92909279T ES92909279T ES2118814T3 ES 2118814 T3 ES2118814 T3 ES 2118814T3 ES 92909279 T ES92909279 T ES 92909279T ES 92909279 T ES92909279 T ES 92909279T ES 2118814 T3 ES2118814 T3 ES 2118814T3
- Authority
- ES
- Spain
- Prior art keywords
- azaspiro
- oxa
- tartrate
- methylene
- dimetil
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
L-TARTRATO DE (-)-(S)-2,8-DIMETIL-3-METILEN-1-OXA-8-AZASPIRO[4,5]DECANO CON UNA ESTABILIDAD DE CONSERVACION SUPERIOR A LA DE OTRAS SALES Y QUE SE PUEDE APLICAR COMO MEDICINA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13961991 | 1991-05-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2118814T3 true ES2118814T3 (es) | 1998-10-01 |
Family
ID=15249510
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES92909279T Expired - Lifetime ES2118814T3 (es) | 1991-05-15 | 1992-04-27 | L-tartrato de (-)-(s)-2,8-dimetil-3-metilen-1-oxa-8-azaspiro(4,5)decano. |
Country Status (11)
Country | Link |
---|---|
US (1) | US5403931A (es) |
EP (1) | EP0590150B1 (es) |
AT (1) | ATE168114T1 (es) |
AU (1) | AU1666392A (es) |
CA (1) | CA2109117A1 (es) |
DE (1) | DE69226187T2 (es) |
DK (1) | DK0590150T3 (es) |
ES (1) | ES2118814T3 (es) |
GR (1) | GR3027686T3 (es) |
RU (1) | RU2057132C1 (es) |
WO (1) | WO1992020683A1 (es) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1995005390A1 (en) * | 1993-08-19 | 1995-02-23 | Merck & Co., Inc. | THERMODYNAMICALLY STABLE CRYSTAL FORM OF 4'-DEOXY-4'-EPI-METHYLAMINO AVERMECTIN B1a/B1b BENZOIC ACID SALT AND PROCESSES FOR ITS PREPARATION |
ES2368824T3 (es) * | 1998-03-27 | 2011-11-22 | Oregon Health & Science University | Vitamina d y sus análogos en el tratamiento de tumores y otros desórdenes hiperproliferativos. |
JP2003063964A (ja) * | 2001-08-28 | 2003-03-05 | Senju Pharmaceut Co Ltd | ドライアイまたはドライアイを伴なう疾病の予防治療剤 |
US7491725B2 (en) | 2004-02-06 | 2009-02-17 | Bristol-Myers Squibb Company | Process for preparing 2-aminothiazole-5-aromatic carboxamides as kinase inhibitors |
KR20080031430A (ko) * | 2005-07-26 | 2008-04-08 | 센주 세이야꾸 가부시키가이샤 | 경피적으로 흡수가능한 안과용 제제 |
WO2007025177A2 (en) * | 2005-08-26 | 2007-03-01 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation |
EP2258358A3 (en) | 2005-08-26 | 2011-09-07 | Braincells, Inc. | Neurogenesis with acetylcholinesterase inhibitor |
EP2377530A3 (en) | 2005-10-21 | 2012-06-20 | Braincells, Inc. | Modulation of neurogenesis by PDE inhibition |
US20070112017A1 (en) | 2005-10-31 | 2007-05-17 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
EP2377531A2 (en) | 2006-05-09 | 2011-10-19 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
US7678808B2 (en) | 2006-05-09 | 2010-03-16 | Braincells, Inc. | 5 HT receptor mediated neurogenesis |
MX2009002496A (es) | 2006-09-08 | 2009-07-10 | Braincells Inc | Combinaciones que contienen un derivado de 4-acilaminopiridina. |
US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
CA2750777C (en) * | 2009-01-26 | 2018-04-03 | Israel Institute For Biological Research | Bicyclic heterocyclic spiro compounds |
WO2010099217A1 (en) | 2009-02-25 | 2010-09-02 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3853758T2 (de) * | 1987-10-05 | 1995-09-07 | Yamanouchi Pharma Co Ltd | Heterozyklische Spiroverbindungen und ihre Herstellung. |
US5075317A (en) * | 1989-06-21 | 1991-12-24 | Fisons Corporation | Spirofurane derivatives |
-
1992
- 1992-04-27 AT AT92909279T patent/ATE168114T1/de not_active IP Right Cessation
- 1992-04-27 US US08/146,133 patent/US5403931A/en not_active Expired - Fee Related
- 1992-04-27 ES ES92909279T patent/ES2118814T3/es not_active Expired - Lifetime
- 1992-04-27 WO PCT/JP1992/000548 patent/WO1992020683A1/ja active IP Right Grant
- 1992-04-27 CA CA002109117A patent/CA2109117A1/en not_active Abandoned
- 1992-04-27 AU AU16663/92A patent/AU1666392A/en not_active Abandoned
- 1992-04-27 EP EP92909279A patent/EP0590150B1/en not_active Expired - Lifetime
- 1992-04-27 DK DK92909279T patent/DK0590150T3/da active
- 1992-04-27 DE DE69226187T patent/DE69226187T2/de not_active Expired - Fee Related
- 1992-04-27 RU RU9293058306A patent/RU2057132C1/ru active
-
1998
- 1998-08-20 GR GR980401862T patent/GR3027686T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
GR3027686T3 (en) | 1998-11-30 |
DE69226187T2 (de) | 1998-10-22 |
EP0590150A1 (en) | 1994-04-06 |
WO1992020683A1 (en) | 1992-11-26 |
ATE168114T1 (de) | 1998-07-15 |
DE69226187D1 (de) | 1998-08-13 |
EP0590150A4 (en) | 1994-06-29 |
AU1666392A (en) | 1992-12-30 |
DK0590150T3 (da) | 1999-04-19 |
US5403931A (en) | 1995-04-04 |
EP0590150B1 (en) | 1998-07-08 |
CA2109117A1 (en) | 1992-11-16 |
RU2057132C1 (ru) | 1996-03-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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