ES2115054T3 - Inhibicion de la hipotension y del shock septico, causados por oxido nitrico, mediante el uso de hemoproteina conteniendo hierro. - Google Patents

Inhibicion de la hipotension y del shock septico, causados por oxido nitrico, mediante el uso de hemoproteina conteniendo hierro.

Info

Publication number
ES2115054T3
ES2115054T3 ES93905917T ES93905917T ES2115054T3 ES 2115054 T3 ES2115054 T3 ES 2115054T3 ES 93905917 T ES93905917 T ES 93905917T ES 93905917 T ES93905917 T ES 93905917T ES 2115054 T3 ES2115054 T3 ES 2115054T3
Authority
ES
Spain
Prior art keywords
nitric oxide
septic shock
caused
hypotension
inhibition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93905917T
Other languages
English (en)
Inventor
Robert G Kilbourn
Angelo Joseph De
Joseph Bonaventura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Apex Bioscience Inc
University of Texas System
Duke University
Original Assignee
Apex Bioscience Inc
University of Texas System
Duke University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Apex Bioscience Inc, University of Texas System, Duke University filed Critical Apex Bioscience Inc
Application granted granted Critical
Publication of ES2115054T3 publication Critical patent/ES2115054T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/41—Porphyrin- or corrin-ring-containing peptides
    • A61K38/42—Haemoglobins; Myoglobins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LA INVENCION SE REFIERE A UN METODO PARA LA PROFILAXIS O TRATAMIENTO DE UN ANIMAL PARA EFECTOS FISIOLOGICOS DETERIORADOS TALES COMO HIPOTENSION SISTEMICA CAUSADA POR LA PRODUCCION DE OXIDO NITRICO INDUCIDO POR UN MODIFICADOR DE RESPUESTA BIOLOGICA. EJEMPLO DE TALES MODIFICADORES DE RESPUESTA BIOLOGICA COMPRENDEN PERO NO LIMITAN UNA CITOQUINA Y UNA ENDOTOXINA. LA INVENCION SE REFIERE TAMBIEN A UN METODO PARA EL TRATAMIENTO DEL ATAQUE SEPTICO.
ES93905917T 1992-02-19 1993-02-16 Inhibicion de la hipotension y del shock septico, causados por oxido nitrico, mediante el uso de hemoproteina conteniendo hierro. Expired - Lifetime ES2115054T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/838,603 US5296466A (en) 1992-02-19 1992-02-19 Inhibition of nitric oxide-mediated hypotension and septic shock with iron-containing hemoprotein

Publications (1)

Publication Number Publication Date
ES2115054T3 true ES2115054T3 (es) 1998-06-16

Family

ID=25277557

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93905917T Expired - Lifetime ES2115054T3 (es) 1992-02-19 1993-02-16 Inhibicion de la hipotension y del shock septico, causados por oxido nitrico, mediante el uso de hemoproteina conteniendo hierro.

Country Status (11)

Country Link
US (6) US5296466A (es)
EP (1) EP0626859B1 (es)
JP (1) JPH07504193A (es)
AT (1) ATE162722T1 (es)
AU (1) AU657212B2 (es)
CA (1) CA2117380C (es)
DE (1) DE69316737T2 (es)
DK (1) DK0626859T3 (es)
ES (1) ES2115054T3 (es)
GR (1) GR3026750T3 (es)
WO (1) WO1993016721A1 (es)

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Also Published As

Publication number Publication date
US5480866A (en) 1996-01-02
US5900403A (en) 1999-05-04
WO1993016721A1 (en) 1993-09-02
AU657212B2 (en) 1995-03-02
US6350729B1 (en) 2002-02-26
CA2117380A1 (en) 1993-09-02
DE69316737D1 (de) 1998-03-05
DK0626859T3 (da) 1998-09-21
US6103690A (en) 2000-08-15
ATE162722T1 (de) 1998-02-15
AU3665593A (en) 1993-09-13
GR3026750T3 (en) 1998-07-31
EP0626859A1 (en) 1994-12-07
EP0626859B1 (en) 1998-01-28
US5674836A (en) 1997-10-07
CA2117380C (en) 2003-04-15
US5296466A (en) 1994-03-22
DE69316737T2 (de) 1998-09-17
JPH07504193A (ja) 1995-05-11

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