ES2113348T3 - Composiciones de vacunas estabilizadas. - Google Patents

Composiciones de vacunas estabilizadas.

Info

Publication number
ES2113348T3
ES2113348T3 ES90913372T ES90913372T ES2113348T3 ES 2113348 T3 ES2113348 T3 ES 2113348T3 ES 90913372 T ES90913372 T ES 90913372T ES 90913372 T ES90913372 T ES 90913372T ES 2113348 T3 ES2113348 T3 ES 2113348T3
Authority
ES
Spain
Prior art keywords
compositions
stabilized vaccines
vaccines
stabilized
diamins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90913372T
Other languages
English (en)
Inventor
Brent Dorval
Marie Chow
Alexander Klibanov
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Massachusetts Institute of Technology
Original Assignee
Massachusetts Institute of Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Institute of Technology filed Critical Massachusetts Institute of Technology
Application granted granted Critical
Publication of ES2113348T3 publication Critical patent/ES2113348T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/125—Picornaviridae, e.g. calicivirus
    • A61K39/13—Poliovirus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32611—Poliovirus
    • C12N2770/32634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

COMPOSICIONES DE VACUNAS QUE CONTIENEN UN VIRUS Y, COMO ESTABILIZADOR, UN COMPUESTO QUE CONTIENE DOS GRUPOS AMINO POR LO MENOS. LOS ESTABILIZADORES INCLUYEN DIAMINAS COMO POR EJEMPLO LA LISINA O LA ETILENDIAMINA DE AMINOACIDOS Y POLIAMINAS COMO POR EJEMPLO LA POLI(ETILENIMINA).
ES90913372T 1989-08-15 1990-08-14 Composiciones de vacunas estabilizadas. Expired - Lifetime ES2113348T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US39399689A 1989-08-15 1989-08-15

Publications (1)

Publication Number Publication Date
ES2113348T3 true ES2113348T3 (es) 1998-05-01

Family

ID=23557105

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90913372T Expired - Lifetime ES2113348T3 (es) 1989-08-15 1990-08-14 Composiciones de vacunas estabilizadas.

Country Status (9)

Country Link
US (1) US5618539A (es)
EP (1) EP0487632B1 (es)
JP (1) JP3064413B2 (es)
AT (1) ATE163547T1 (es)
CA (1) CA2065023A1 (es)
DE (1) DE69032102T2 (es)
DK (1) DK0487632T3 (es)
ES (1) ES2113348T3 (es)
WO (1) WO1991002543A1 (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4370451B2 (ja) * 2001-09-28 2009-11-25 大塚製薬株式会社 医薬組成物
AU2003225057A1 (en) * 2002-04-19 2003-11-03 The Regents Of The University Of Michigan Polymer compositions that stabilize and control the release of formaldehyde-treated vaccine antigens
US20060110406A1 (en) * 2003-02-25 2006-05-25 Medimmune Vaccines, Inc. Refrigerator-temperature stable influenza vaccine compositions
KR101190932B1 (ko) * 2003-02-25 2012-10-16 메디뮨 엘엘씨 인플루엔자 백신 조성물의 제조 방법
US20060141483A1 (en) * 2004-12-23 2006-06-29 Calton Gary J Stabilization of viral compositions
TWI398272B (zh) 2005-03-08 2013-06-11 Intervet Int Bv 化學定義的安定劑
BRPI0800357A2 (pt) * 2008-03-10 2009-10-27 Fundacao Oswaldo Cruz método para produção de uma vacina estabilizada
US20110212127A1 (en) * 2008-09-24 2011-09-01 Stabilitech Ltd. Method for Preserving Polypeptides Using a Sugar and Polyethyleneimine
WO2010035001A1 (en) * 2008-09-24 2010-04-01 Stabilitech Ltd Method for preserving polypeptides using a sugar and polyethyleneimine
CA2795013C (en) 2010-03-31 2018-10-16 Stabilitech Ltd. Stabilisation of viral particles
BR112012025044A2 (pt) 2010-03-31 2016-06-21 Stabilitech Ltd método para conservar adjuvantes de alum e vacinas com adjuvantes de alum
US20130164296A1 (en) 2010-03-31 2013-06-27 Jeffrey Drew Excipients for Stabilising Viral Particles, Polypeptides or Biological Material
EP3744833A1 (en) * 2011-06-28 2020-12-02 Leukocare Ag Stabilisation method for viruses
GB201117233D0 (en) 2011-10-05 2011-11-16 Stabilitech Ltd Stabilisation of polypeptides
US9283270B2 (en) 2012-01-20 2016-03-15 Serum Institute Of India Ltd. Method for stabilization of biological molecules
TWI690322B (zh) * 2012-10-02 2020-04-11 法商傳斯堅公司 含病毒的調配物及其使用
SI3010537T1 (sl) 2013-06-17 2018-09-28 De Staat der Nederlanden, Vert. Door de Minister Van Vws Ministerie Van Volksgezondheid Welzijn en Sport Metode za preprečevanje agregacije virusnih komponent
GB201406569D0 (en) 2014-04-11 2014-05-28 Stabilitech Ltd Vaccine compositions
GB2562241B (en) 2017-05-08 2022-04-06 Stabilitech Biopharma Ltd Vaccine compositions

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3097143A (en) * 1960-03-30 1963-07-09 Merck & Co Inc Myristyl-gamma-picolinium chloride preserved polio vaccine and its production
US3097142A (en) * 1960-03-30 1963-07-09 Merck & Co Inc Benzyl alcohol stabilized polio vaccines and production thereof
US3128229A (en) * 1961-10-05 1964-04-07 Baylor Medical Foundation Stabilization of viral vaccine and inactivation of adventitious tissue culture contaminants therein
GB1564998A (en) * 1975-03-21 1980-04-16 Connaught Lab Vaccine and stabilizing solution therefor
US4338335A (en) * 1980-02-05 1982-07-06 Merck & Co., Inc. Vaccine stabilizer containing L-glutamic acid and L-arginine
US4337242A (en) * 1980-02-05 1982-06-29 Merck & Co., Inc. Vaccine stabilizer containing L-glutamic acid and L-arginine
FR2505657A1 (fr) * 1981-05-13 1982-11-19 Pasteur Institut Perfectionnements apportes aux agents de stabilisation de virus vivants pour la preparation de vaccins, et vaccins stabilises contenant lesdits agents de stabilisation

Also Published As

Publication number Publication date
EP0487632B1 (en) 1998-03-04
US5618539A (en) 1997-04-08
DE69032102T2 (de) 1998-06-25
DE69032102D1 (de) 1998-04-09
ATE163547T1 (de) 1998-03-15
JPH04506973A (ja) 1992-12-03
JP3064413B2 (ja) 2000-07-12
DK0487632T3 (da) 1998-05-25
EP0487632A1 (en) 1992-06-03
WO1991002543A1 (en) 1991-03-07
CA2065023A1 (en) 1991-02-16

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