ES2113348T3 - COMPOSITIONS OF STABILIZED VACCINES. - Google Patents

COMPOSITIONS OF STABILIZED VACCINES.

Info

Publication number
ES2113348T3
ES2113348T3 ES90913372T ES90913372T ES2113348T3 ES 2113348 T3 ES2113348 T3 ES 2113348T3 ES 90913372 T ES90913372 T ES 90913372T ES 90913372 T ES90913372 T ES 90913372T ES 2113348 T3 ES2113348 T3 ES 2113348T3
Authority
ES
Spain
Prior art keywords
compositions
stabilized vaccines
vaccines
stabilized
diamins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90913372T
Other languages
Spanish (es)
Inventor
Brent Dorval
Marie Chow
Alexander Klibanov
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Massachusetts Institute of Technology
Original Assignee
Massachusetts Institute of Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Institute of Technology filed Critical Massachusetts Institute of Technology
Application granted granted Critical
Publication of ES2113348T3 publication Critical patent/ES2113348T3/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/125—Picornaviridae, e.g. calicivirus
    • A61K39/13—Poliovirus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32611—Poliovirus
    • C12N2770/32634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

COMPOSICIONES DE VACUNAS QUE CONTIENEN UN VIRUS Y, COMO ESTABILIZADOR, UN COMPUESTO QUE CONTIENE DOS GRUPOS AMINO POR LO MENOS. LOS ESTABILIZADORES INCLUYEN DIAMINAS COMO POR EJEMPLO LA LISINA O LA ETILENDIAMINA DE AMINOACIDOS Y POLIAMINAS COMO POR EJEMPLO LA POLI(ETILENIMINA).VACCINE COMPOSITIONS CONTAINING A VIRUS AND, AS A STABILIZER, A COMPOUND CONTAINING AT LEAST TWO AMINO GROUPS. STABILIZERS INCLUDE DIAMINS LIKE FOR EXAMPLE LYSINE OR ETHYLENDIAMINE OF AMINO ACIDS AND POLYAMINES LIKE FOR EXAMPLE POLY (ETHYLENIMINE).

ES90913372T 1989-08-15 1990-08-14 COMPOSITIONS OF STABILIZED VACCINES. Expired - Lifetime ES2113348T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US39399689A 1989-08-15 1989-08-15

Publications (1)

Publication Number Publication Date
ES2113348T3 true ES2113348T3 (en) 1998-05-01

Family

ID=23557105

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90913372T Expired - Lifetime ES2113348T3 (en) 1989-08-15 1990-08-14 COMPOSITIONS OF STABILIZED VACCINES.

Country Status (9)

Country Link
US (1) US5618539A (en)
EP (1) EP0487632B1 (en)
JP (1) JP3064413B2 (en)
AT (1) ATE163547T1 (en)
CA (1) CA2065023A1 (en)
DE (1) DE69032102T2 (en)
DK (1) DK0487632T3 (en)
ES (1) ES2113348T3 (en)
WO (1) WO1991002543A1 (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4370451B2 (en) * 2001-09-28 2009-11-25 大塚製薬株式会社 Pharmaceutical composition
AU2003225057A1 (en) * 2002-04-19 2003-11-03 The Regents Of The University Of Michigan Polymer compositions that stabilize and control the release of formaldehyde-treated vaccine antigens
US20060110406A1 (en) * 2003-02-25 2006-05-25 Medimmune Vaccines, Inc. Refrigerator-temperature stable influenza vaccine compositions
EP2481819A1 (en) 2003-02-25 2012-08-01 MedImmune Vaccines, Inc. Cross flow filtration in the production of stabilized influenza vaccine compositions
US20060141483A1 (en) * 2004-12-23 2006-06-29 Calton Gary J Stabilization of viral compositions
TWI398272B (en) * 2005-03-08 2013-06-11 Intervet Int Bv Chemically defined stabiliser
BRPI0800357A2 (en) * 2008-03-10 2009-10-27 Fundacao Oswaldo Cruz method for producing a stabilized vaccine
CN102164943A (en) * 2008-09-24 2011-08-24 稳定技术有限公司 Method for preserving polypeptides using a sugar and polyethyleneimine
US20110212127A1 (en) * 2008-09-24 2011-09-01 Stabilitech Ltd. Method for Preserving Polypeptides Using a Sugar and Polyethyleneimine
WO2011121301A1 (en) 2010-03-31 2011-10-06 Stabilitech Ltd Excipients for stabilising viral particles, polypeptides or biological material
HUE026885T2 (en) 2010-03-31 2016-08-29 Stabilitech Ltd Stabilisation of viral particles
EP2552410B1 (en) 2010-03-31 2018-10-24 Stabilitech Biopharma Ltd Method for preserving alum adjuvants and alum-adjuvanted vaccines
CN108588035A (en) * 2011-06-28 2018-09-28 白血球保健股份有限公司 Virus or the Novel stabilisation method of bacterium
GB201117233D0 (en) 2011-10-05 2011-11-16 Stabilitech Ltd Stabilisation of polypeptides
US9283270B2 (en) 2012-01-20 2016-03-15 Serum Institute Of India Ltd. Method for stabilization of biological molecules
TWI690322B (en) * 2012-10-02 2020-04-11 法商傳斯堅公司 Virus-containing formulation and use thereof
PL3010537T3 (en) 2013-06-17 2019-03-29 De Staat Der Nederlanden, Vert. Door De Minister Van Vws, Ministerie Van Volksgezondheid, Welzijn En Sport Methods for the prevention of aggregation of viral components
GB201406569D0 (en) 2014-04-11 2014-05-28 Stabilitech Ltd Vaccine compositions
GB2562241B (en) 2017-05-08 2022-04-06 Stabilitech Biopharma Ltd Vaccine compositions

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3097142A (en) * 1960-03-30 1963-07-09 Merck & Co Inc Benzyl alcohol stabilized polio vaccines and production thereof
US3097143A (en) * 1960-03-30 1963-07-09 Merck & Co Inc Myristyl-gamma-picolinium chloride preserved polio vaccine and its production
US3128229A (en) * 1961-10-05 1964-04-07 Baylor Medical Foundation Stabilization of viral vaccine and inactivation of adventitious tissue culture contaminants therein
GB1564998A (en) * 1975-03-21 1980-04-16 Connaught Lab Vaccine and stabilizing solution therefor
US4337242A (en) * 1980-02-05 1982-06-29 Merck & Co., Inc. Vaccine stabilizer containing L-glutamic acid and L-arginine
US4338335A (en) * 1980-02-05 1982-07-06 Merck & Co., Inc. Vaccine stabilizer containing L-glutamic acid and L-arginine
FR2505657A1 (en) * 1981-05-13 1982-11-19 Pasteur Institut IMPROVEMENTS IN LIVE STABILIZING AGENTS FOR THE PREPARATION OF VACCINES, AND STABILIZED VACCINES CONTAINING SAID STABILIZING AGENTS

Also Published As

Publication number Publication date
WO1991002543A1 (en) 1991-03-07
DE69032102T2 (en) 1998-06-25
DE69032102D1 (en) 1998-04-09
JPH04506973A (en) 1992-12-03
EP0487632B1 (en) 1998-03-04
DK0487632T3 (en) 1998-05-25
US5618539A (en) 1997-04-08
ATE163547T1 (en) 1998-03-15
EP0487632A1 (en) 1992-06-03
CA2065023A1 (en) 1991-02-16
JP3064413B2 (en) 2000-07-12

Similar Documents

Publication Publication Date Title
ES2113348T3 (en) COMPOSITIONS OF STABILIZED VACCINES.
ES2149267T3 (en) SUBSTITUTED CYCLIC CARBONYLL AND DERIVED FROM THE SAME USEFUL AS RETROVIRAL PROTEASE INHIBITORS.
BR9201848A (en) PROCESS FOR THE PREPARATION OF VIRUS PARTICUALS FOR VACCINES, VACCINE, AND, PROCESS FOR THE TREATMENT OR PROPHYLAXIS OF A VIRAL INFECTION IN A MAMMALIAN WITH THE SAME NEED
DE3278344D1 (en) Stabilization of influenza virus vaccine
MX165474B (en) FABRIC SOFTENING COMPOSITION
DK0414263T3 (en) Process for stabilizing a solid pharmaceutical composition containing cyclic amino acids
ES2080119T3 (en) SOFTENING COMPOSITION OF FABRICS.
ATE196773T1 (en) POULTRY VACCINE CONTAINING INFECTIOUS BRONCHITIS VIRUS 4/91
DE69129207T2 (en) Peptides derived from virus-HIV-envelope glycoproteins, their use for the detection of infection of these viruses and for the vaccination against AIDS
ES2108772T3 (en) SUBSTITUTED AMINO PHOSPHONATE DERIVATIVES, PROCEDURE FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM.
ES2053077T3 (en) PIPERIDINIL, PIRROLIDINIL AND PIPERAZINIL ALKYLPHENOL ETHERS WITH ANTIRHINOVIRAL PROPERTIES.
DK1666057T3 (en) Method for Preparing an Acellular Vaccine Containing Bordetella pertussis Antigens
EA200100711A1 (en) ANALOGUES OF NUCLEOSIDE (OPTIONS) AND THEIR APPLICATION, COMBINATION AND METHOD OF TREATING VIRAL INFECTIONS, PHARMACEUTICAL COMPOSITION
ES8800358A1 (en) Vaccinal polypeptides.
DE68912809T2 (en) Process for the preparation of bis (2,2,6,6-tetramethyl-4-piperidyl) amine.
ES2132330T3 (en) VACCINE FOR THE PROTECTION OF HORSES AGAINST INFECTION WITH THE EQUINE HERPES VIRUS.
ES2059767T3 (en) DERIVATIVE OF 1,4-DIHYDROPYRIDINE.
ES2002662A6 (en) Oligomeric diazaoxaspirodecanes, their preparation and their use as light protectors for polymers.
AU6977387A (en) Stable injectable pharmaceutical formulation of 1,4- dihydroxy-5,8-bis((2-(2-hydroxyethylamino)-ethyl)amino)- anthraquinone, dihydrochloride
ES2058379T3 (en) MONOPERSULPHATES OF ACIDS (POLI) PERCARBOXYLLIC HETEROCICLICOS CONTAINING NITROGEN.
ES2096559T3 (en) INTERFERON GAMMA HUMANO, PROCEDURE FOR THE PREPARATION OF SUCH INTERFERON GAMMA HUMANO, AND ITS USE.
BR9205877A (en) Process and composition for the treatment of herpes infections.
ES2084587T3 (en) NON-REVERTING RNA VIRUSES.
DK553587D0 (en) ACYLED 9,10-ANTHRACENDICARBOXALDEHYD-BIS (2-IMIDAZOLIN-2-YL HYDRAZONES), PROCEDURE FOR THEIR PREPARATION AND THEIR USE
ES2056374T3 (en) IMPROVEMENTS IN CHEMICAL COMPOUNDS.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 487632

Country of ref document: ES