ES2112405T3 - Procedimiento para la fabricacion de manitol. - Google Patents

Procedimiento para la fabricacion de manitol.

Info

Publication number
ES2112405T3
ES2112405T3 ES93401858T ES93401858T ES2112405T3 ES 2112405 T3 ES2112405 T3 ES 2112405T3 ES 93401858 T ES93401858 T ES 93401858T ES 93401858 T ES93401858 T ES 93401858T ES 2112405 T3 ES2112405 T3 ES 2112405T3
Authority
ES
Spain
Prior art keywords
mannosa
fraction
stage
enriched
enzymatic isomerization
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93401858T
Other languages
English (en)
Inventor
Francis Devos
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roquette Freres SA
Original Assignee
Roquette Freres SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roquette Freres SA filed Critical Roquette Freres SA
Application granted granted Critical
Publication of ES2112405T3 publication Critical patent/ES2112405T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/24—Preparation of compounds containing saccharide radicals produced by the action of an isomerase, e.g. fructose

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)

Abstract

LA INVENCION TIENE POR OBJETO A UN PROCESO DE FABRICACION DE MANNITOL EN EL CUAL: RABE DE FRUCTOSA QUE CONTIENE AL MENOS UN 15% DE GLUCOSA A UNA ISOMERIZACION ENZIMATICA CON LA AYUDA DE AL MENOS UNA ENZIMA CAPAZ DE INTERCONVERTIR LA FRUCTOSA Y LA MANNOSA, DICHA ISOMERIZACION ENZIMATICA CONDUCE A LA OBTENCION DE UNA MEZCLA DE FRUCTOSA Y DE MANNOSA CONTENIENDO AL MENOS UN 15% DE MANNOSA; UNA SEGUNDA ETAPA SE SOMETE LA DICHA MEZCLA A UN TRATAMIENTO DE SEPARACION CROMATOGRAFIA DE FORMA QUE SE OBTENGA AL MENOS DOS FRACCIONES DE LAS CUALES UNA (FRACCION X1) ESTA MUY ENRIQUECIDA EN MANNOSA Y LA OTRA (FRACCION X2) ESTA MUY ENRIQUECIDA EN FRUCTOSA; LA FRACCION X2 EN CABEZA DE LA ETAPA DE ISOMERIZACION ENZIMATICA; EN UNA CUARTA ETAPA SE HIDROGENA LA FRACCION X1 FUERTEMENTE ENRIQUECIDA EN MANNOSA DE FORMA QUE SE OBTENGA UN JARABE RICO EN MANNITOL.
ES93401858T 1992-07-22 1993-07-19 Procedimiento para la fabricacion de manitol. Expired - Lifetime ES2112405T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9209053A FR2694019B1 (fr) 1992-07-22 1992-07-22 Procédé de fabrication de mannitol.

Publications (1)

Publication Number Publication Date
ES2112405T3 true ES2112405T3 (es) 1998-04-01

Family

ID=9432149

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93401858T Expired - Lifetime ES2112405T3 (es) 1992-07-22 1993-07-19 Procedimiento para la fabricacion de manitol.

Country Status (8)

Country Link
US (1) US5466795A (es)
EP (1) EP0580490B1 (es)
JP (1) JPH06157379A (es)
BR (1) BR9302941A (es)
DE (1) DE69315902T2 (es)
ES (1) ES2112405T3 (es)
FI (1) FI102841B1 (es)
FR (1) FR2694019B1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19820957A1 (de) * 1998-05-11 1999-11-25 Merck Patent Gmbh Verfahren zur Herstellung von Mannit
US6451123B1 (en) 1999-01-14 2002-09-17 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Process for the separation of sugars
BE1021455B1 (nl) * 2012-11-22 2015-11-26 Syral Belgium Nv Werkwijze voor het verwerken van substraten die een uitgangsstof voor mannitol omvatten.
CN114436768A (zh) * 2021-12-28 2022-05-06 广东焕发药业有限公司 一种从甘露醇母液中回收山梨醇和甘露醇的方法

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2985589A (en) * 1957-05-22 1961-05-23 Universal Oil Prod Co Continuous sorption process employing fixed bed of sorbent and moving inlets and outlets
US3044904A (en) * 1960-02-15 1962-07-17 Central Aguirre Sugar Company Separation of dextrose and levulose
US3416961A (en) * 1964-01-07 1968-12-17 Colonial Sugar Refining Co Process for the separation of fructose and glucose
US3785864A (en) * 1970-07-23 1974-01-15 Boehringer Mannheim Gmbh Process for the chromatographic separation of multi-component mixtures containing glucose
US3692582A (en) * 1970-07-31 1972-09-19 Suomen Sokeri Oy Procedure for the separation of fructose from the glucose of invert sugar
US4029878A (en) * 1975-05-19 1977-06-14 Ici United States Inc. Process for preparing mannitol from glucose
JPS5277007A (en) * 1975-12-19 1977-06-29 Towa Kasei Kogyo Kk Method of producing aqueous hexose and hexoseealcohol containing solution
US4226977A (en) * 1976-05-27 1980-10-07 Uop Inc. Process for separating a ketose from an aldose by selective adsorption
FR2353562A1 (fr) * 1976-06-04 1977-12-30 Roquette Freres Procede de fabrication de particules insolubles a activite enzymatique
JPS5326336A (en) * 1976-08-24 1978-03-11 Toray Industries Method of fractional absorption for saccharides
FI69248C (fi) * 1976-12-21 1986-01-10 Mitsubishi Chem Ind Foerfarande foer reglering av operationsprocessen av en simulerad roerlig baedd
GB1540556A (en) * 1977-01-11 1979-02-14 Ici America Inc Separation of mannose from glucose
JPS6055162B2 (ja) * 1977-05-26 1985-12-04 参松工業株式会社 カラムクロマト分離法
US4173514A (en) * 1977-06-02 1979-11-06 Ici Americas Inc. High mannitol process (enzymatic isomerization)
US4292451A (en) * 1978-03-30 1981-09-29 Ici Americas Inc. High mannitol process (alkaline hydrogenation in presence of alkali metal carbonate)
US4405455A (en) * 1978-11-02 1983-09-20 Mitsubishi Chemical Industries Limited Adsorption separation apparatus
AU540231B2 (en) * 1978-11-02 1984-11-08 Mitsubishi Kasei Corporation Adsorption separation method and apparatus
US4293346A (en) * 1979-11-05 1981-10-06 Uop Inc. Simulated countercurrent sorption process employing ion exchange resins with backflushing
US4422881A (en) * 1980-10-29 1983-12-27 Roquette Freres Installation and process for the continuous separation of mixtures of sugars and/or of polyols by selective adsorption
US4412866A (en) * 1981-05-26 1983-11-01 The Amalgamated Sugar Company Method and apparatus for the sorption and separation of dissolved constituents
EP0074713A1 (en) * 1981-09-14 1983-03-23 Ici Americas Inc. Method for concentrating mannose in aqueous glucose solutions
US4492755A (en) * 1982-06-30 1985-01-08 Nabisco Brands, Inc. Process for isomerizing L-mannose to L-fructose
US4471114A (en) * 1982-12-30 1984-09-11 Union Carbide Corporation Separation of mannose by selective adsorption on zeolitic molecular sieves
DE3326546A1 (de) * 1983-07-22 1985-02-07 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V., 8000 München Verfahren zur kontinuierlichen enzymatischen herstellung von gluconsaeure oder ihren derivaten und sorbit und/oder mannit
US4692514A (en) * 1985-12-20 1987-09-08 Uop Inc. Process for separating ketoses from alkaline- or pyridine-catalyzed isomerization products
US5049494A (en) * 1989-02-08 1991-09-17 Allied-Signal Inc. Conversion of mannose to fructose

Also Published As

Publication number Publication date
FR2694019A1 (fr) 1994-01-28
FI102841B (fi) 1999-02-26
BR9302941A (pt) 1994-02-16
FI933214A0 (fi) 1993-07-15
EP0580490B1 (fr) 1997-12-29
US5466795A (en) 1995-11-14
FI933214A (fi) 1994-01-23
FI102841B1 (fi) 1999-02-26
EP0580490A1 (fr) 1994-01-26
DE69315902T2 (de) 1998-05-07
FR2694019B1 (fr) 1994-10-14
JPH06157379A (ja) 1994-06-03
DE69315902D1 (de) 1998-02-05

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