ES2109970T3 - Dietanolato del etoposido 4'-fosfato cristalino. - Google Patents

Dietanolato del etoposido 4'-fosfato cristalino.

Info

Publication number
ES2109970T3
ES2109970T3 ES92116749T ES92116749T ES2109970T3 ES 2109970 T3 ES2109970 T3 ES 2109970T3 ES 92116749 T ES92116749 T ES 92116749T ES 92116749 T ES92116749 T ES 92116749T ES 2109970 T3 ES2109970 T3 ES 2109970T3
Authority
ES
Spain
Prior art keywords
ethoposide
diethanolate
crystal phosphate
phosphate
crystal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92116749T
Other languages
English (en)
Spanish (es)
Inventor
Denis Favreau
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of ES2109970T3 publication Critical patent/ES2109970T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
ES92116749T 1991-10-08 1992-09-30 Dietanolato del etoposido 4'-fosfato cristalino. Expired - Lifetime ES2109970T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/773,056 US5648474A (en) 1991-10-08 1991-10-08 Crystalline etoposide 4'-phosphate diethanolate

Publications (1)

Publication Number Publication Date
ES2109970T3 true ES2109970T3 (es) 1998-02-01

Family

ID=25097069

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92116749T Expired - Lifetime ES2109970T3 (es) 1991-10-08 1992-09-30 Dietanolato del etoposido 4'-fosfato cristalino.

Country Status (27)

Country Link
US (1) US5648474A (https=)
EP (1) EP0537555B1 (https=)
JP (1) JP3205816B2 (https=)
KR (1) KR100243981B1 (https=)
CN (1) CN1030610C (https=)
AT (1) ATE156832T1 (https=)
AU (1) AU650572B2 (https=)
CA (1) CA2079581C (https=)
CZ (1) CZ283735B6 (https=)
DE (1) DE69221573T2 (https=)
DK (1) DK0537555T3 (https=)
EG (1) EG20187A (https=)
ES (1) ES2109970T3 (https=)
FI (1) FI105034B (https=)
GR (1) GR3025176T3 (https=)
HU (2) HU213606B (https=)
IL (1) IL103262A (https=)
MX (1) MX9205777A (https=)
MY (1) MY108969A (https=)
NO (1) NO178342C (https=)
NZ (1) NZ244521A (https=)
PH (1) PH31666A (https=)
PL (1) PL168332B1 (https=)
RU (1) RU2042686C1 (https=)
SK (1) SK298692A3 (https=)
TW (1) TW239863B (https=)
ZA (1) ZA926903B (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5459248A (en) * 1993-11-04 1995-10-17 Bristol-Myers Squibb Company Process of preparing etoposide phosphate and etoposide

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4670578A (en) * 1983-08-29 1987-06-02 Merck & Co., Inc. Process for crystalline salts of L or (S)-3-(3,4-dihydroxyphenyl)-2-methylalanine esters
US4914222A (en) * 1983-08-29 1990-04-03 Merck & Co., Inc. Crystalline salts of L or (S)-3-(3,4-dihydroxyphenyl)-2-methylalanine esters and process
US4713246A (en) * 1984-03-19 1987-12-15 Bristol-Myers Company Etoposide oral dosage form
US4775751A (en) * 1985-06-03 1988-10-04 Eli Lilly & Company Process for cephalexin hydrochloride alcoholates
US4927638A (en) * 1986-10-08 1990-05-22 Bristol-Myers Company Etoposide solutions
US4904768A (en) * 1987-08-04 1990-02-27 Bristol-Myers Company Epipodophyllotoxin glucoside 4'-phosphate derivatives
DE68912721T2 (de) * 1988-11-16 1994-05-11 Nippon Kayaku Kk Kristallines Hydrochlorid von einer Etoposid-2-dimethylamino-Verbindung und Verfahren zur Herstellung davon.
US5081234A (en) * 1990-04-30 1992-01-14 Bristol-Myers Squibb Co. 4'-demethylepipodophyllotoxin glycosides

Also Published As

Publication number Publication date
SK278935B6 (sk) 1998-04-08
EP0537555B1 (en) 1997-08-13
ATE156832T1 (de) 1997-08-15
IL103262A0 (en) 1993-02-21
CZ298692A3 (en) 1993-04-14
FI105034B (fi) 2000-05-31
HU9203119D0 (en) 1992-12-28
MY108969A (en) 1996-11-30
EG20187A (en) 1997-09-30
KR100243981B1 (ko) 2000-02-01
FI924359L (fi) 1993-04-09
AU2530192A (en) 1993-04-22
FI924359A0 (fi) 1992-09-29
NO178342C (no) 1996-03-06
PL296078A1 (en) 1993-04-19
NO923754L (no) 1993-04-13
DK0537555T3 (da) 1998-01-26
TW239863B (https=) 1995-02-01
NO178342B (no) 1995-11-27
JPH05194575A (ja) 1993-08-03
CA2079581A1 (en) 1993-04-09
US5648474A (en) 1997-07-15
CZ283735B6 (cs) 1998-06-17
ZA926903B (en) 1993-05-03
CN1030610C (zh) 1996-01-03
HU213606B (en) 1997-08-28
PL168332B1 (pl) 1996-02-29
AU650572B2 (en) 1994-06-23
DE69221573D1 (de) 1997-09-18
JP3205816B2 (ja) 2001-09-04
CN1071432A (zh) 1993-04-28
DE69221573T2 (de) 1998-02-26
RU2042686C1 (ru) 1995-08-27
SK298692A3 (en) 1998-04-08
IL103262A (en) 1997-06-10
HU211672A9 (en) 1995-12-28
NO923754D0 (no) 1992-09-28
NZ244521A (en) 1994-02-25
MX9205777A (es) 1993-04-01
GR3025176T3 (en) 1998-02-27
CA2079581C (en) 2002-11-12
EP0537555A1 (en) 1993-04-21
PH31666A (en) 1999-01-12
HUT62309A (en) 1993-04-28
KR930007968A (ko) 1993-05-20

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