ES2109530T3 - Derivados de acidos fenil-ciclohexano-carboxilicos heterotriciclicamente sustituidos. - Google Patents

Derivados de acidos fenil-ciclohexano-carboxilicos heterotriciclicamente sustituidos.

Info

Publication number
ES2109530T3
ES2109530T3 ES94103448T ES94103448T ES2109530T3 ES 2109530 T3 ES2109530 T3 ES 2109530T3 ES 94103448 T ES94103448 T ES 94103448T ES 94103448 T ES94103448 T ES 94103448T ES 2109530 T3 ES2109530 T3 ES 2109530T3
Authority
ES
Spain
Prior art keywords
substituted
derivatives
heterotriciclicamente
cycllohexane
fenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94103448T
Other languages
English (en)
Spanish (es)
Inventor
Ulrich E Dr Muller
Jurgen Dr Dressel
Peter Dr Fey
Rudolf H Dr Hanko
Walter Dr Hubsch
Thomas Dr Kramer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Application granted granted Critical
Publication of ES2109530T3 publication Critical patent/ES2109530T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/86—Carbazoles; Hydrogenated carbazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the ring system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
ES94103448T 1993-03-18 1994-03-07 Derivados de acidos fenil-ciclohexano-carboxilicos heterotriciclicamente sustituidos. Expired - Lifetime ES2109530T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4308788A DE4308788A1 (de) 1993-03-18 1993-03-18 Hetero-tricyclisch-substituierte Phenyl-cyclohexan-carbonsäurederivate

Publications (1)

Publication Number Publication Date
ES2109530T3 true ES2109530T3 (es) 1998-01-16

Family

ID=6483216

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94103448T Expired - Lifetime ES2109530T3 (es) 1993-03-18 1994-03-07 Derivados de acidos fenil-ciclohexano-carboxilicos heterotriciclicamente sustituidos.

Country Status (23)

Country Link
US (3) US5478836A (el)
EP (1) EP0617035B1 (el)
JP (1) JPH07165710A (el)
CN (1) CN1097756A (el)
AT (1) ATE160146T1 (el)
AU (1) AU670487B2 (el)
CA (1) CA2119095A1 (el)
CZ (1) CZ62494A3 (el)
DE (2) DE4308788A1 (el)
DK (1) DK0617035T3 (el)
ES (1) ES2109530T3 (el)
FI (1) FI941230A (el)
GR (1) GR3025817T3 (el)
HU (1) HU216829B (el)
IL (1) IL108997A (el)
NO (1) NO301826B1 (el)
NZ (1) NZ260096A (el)
PL (1) PL175560B1 (el)
RU (1) RU2125990C1 (el)
SI (1) SI0617035T1 (el)
SK (1) SK32194A3 (el)
TW (1) TW241264B (el)
ZA (1) ZA941878B (el)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2140722A1 (en) * 1994-01-24 1995-07-25 Joseph A. Jakubowski Beta-carboline thromboxane synthase inhibitors
US5550118A (en) * 1994-01-31 1996-08-27 Eli Lilly And Company Polyhydronorharman synthase inhibitors
DE4435477A1 (de) 1994-10-04 1996-04-11 Bayer Ag Cycloalkano-indol- und -azaindol-derivate
HRP960015B1 (en) * 1995-02-01 2000-12-31 Bayer Ag Substituted indole derivatives
DE19525028A1 (de) * 1995-07-10 1997-01-16 Bayer Ag Amide und Sulfonamide von heterocyclisch substituierten Benzylaminen
WO1998045263A1 (en) * 1997-04-07 1998-10-15 Georgetown University Analogs of cocaine
WO1999051598A1 (en) * 1998-04-02 1999-10-14 Neurogen Corporation SUBSTITUTED 9H-PYRIDINO[2,3-b]INDOLE AND 9H-PYRIMIDINO[4,5-b]INDOLE DERIVATIVES: SELECTIVE NEUROPEPTIDE y RECEPTOR LIGANDS
EP1502936A1 (en) * 2002-03-25 2005-02-02 Idemitsu Kosan Co., Ltd. Material for organic electroluminescent element and organic electroluminescent element employing the same
WO2010009068A2 (en) * 2008-07-16 2010-01-21 Bristol-Myers Squibb Company Cyclohexenyl modulators of chemokine receptor activity

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH501623A (de) * 1967-12-18 1971-01-15 Ruetgerswerke Ag Verfahren zur Herstellung von 2-Chlorpyridin und seinen Derivaten
US4719211A (en) * 1984-05-01 1988-01-12 American Home Products Corporation 2,3,4,9-tetrahydro-2-heteroarylalkyl-1H-pyrido(3,4-B)indoles having antihypertensive properties
DE3535928A1 (de) * 1985-10-04 1987-04-09 Schering Ag Tetrahydro-(beta)-carboline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3535927A1 (de) * 1985-10-04 1987-04-09 Schering Ag 3-vinyl- und 3-ethinyl-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel
GB8600651D0 (en) * 1986-01-11 1986-02-19 Beecham Group Plc Compounds
CA1334092C (en) * 1986-07-11 1995-01-24 David John Carini Angiotensin ii receptor blocking imidazoles
CA1338238C (en) * 1988-01-07 1996-04-09 David John Carini Angiotensin ii receptor blocking imidazoles and combinations thereof with diuretics and nsaids
IE64514B1 (en) * 1989-05-23 1995-08-09 Zeneca Ltd Azaindenes
GB8911854D0 (en) * 1989-05-23 1989-07-12 Ici Plc Heterocyclic compounds
US5164407A (en) * 1989-07-03 1992-11-17 Merck & Co., Inc. Substituted imidazo-fused 5-membered ring heterocycles and their use as angiotensin ii antagonsists
US5124335A (en) * 1991-01-30 1992-06-23 Merck & Co., Inc. Substituted pyrollo-fused 6 membered heterocycles as angiotensin ii antagonists
FR2672598A1 (fr) * 1991-02-11 1992-08-14 Adir Nouveaux inhibiteurs de n-myristoyltransferase, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
GB9109246D0 (en) * 1991-04-30 1991-06-19 Ici Plc Nitrogen derivatives
DE4118741A1 (de) * 1991-06-05 1992-12-10 Schering Ag Neue hetaryloxy-(beta)-carboline, deren herstellung und verwendung in arzneimitteln
US5212195A (en) * 1992-05-13 1993-05-18 Syntex (U.S.A.) Inc. Substituted indole antagonists derivatives which are angiotensin II
TW281667B (el) * 1994-02-03 1996-07-21 Synthelabo

Also Published As

Publication number Publication date
DE4308788A1 (de) 1994-09-22
EP0617035B1 (de) 1997-11-12
SI0617035T1 (en) 1998-02-28
GR3025817T3 (en) 1998-03-31
FI941230A (fi) 1994-09-19
HU216829B (hu) 1999-09-28
US5834481A (en) 1998-11-10
US5478836A (en) 1995-12-26
NO940966L (no) 1994-09-19
IL108997A (en) 1997-04-15
JPH07165710A (ja) 1995-06-27
ATE160146T1 (de) 1997-11-15
NZ260096A (en) 1996-02-27
ZA941878B (en) 1994-10-18
PL175560B1 (pl) 1999-01-29
HU9400784D0 (en) 1994-06-28
DK0617035T3 (da) 1998-07-27
CA2119095A1 (en) 1994-09-19
DE59404557D1 (de) 1997-12-18
US5708003A (en) 1998-01-13
SK32194A3 (en) 1994-12-07
AU5788594A (en) 1994-09-22
EP0617035A1 (de) 1994-09-28
TW241264B (el) 1995-02-21
CN1097756A (zh) 1995-01-25
AU670487B2 (en) 1996-07-18
NO940966D0 (no) 1994-03-17
NO301826B1 (no) 1997-12-15
CZ62494A3 (en) 1994-10-19
HUT67040A (en) 1995-01-30
FI941230A0 (fi) 1994-03-16
RU2125990C1 (ru) 1999-02-10
IL108997A0 (en) 1994-06-24

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