IL108997A - 2-(4-heterotricyclically substituted methylphenyl)- cyclohexane-1- carboxylic acid derivatives, their preparation and pharmaceutical compositions containing them - Google Patents

2-(4-heterotricyclically substituted methylphenyl)- cyclohexane-1- carboxylic acid derivatives, their preparation and pharmaceutical compositions containing them

Info

Publication number
IL108997A
IL108997A IL108997A IL10899794A IL108997A IL 108997 A IL108997 A IL 108997A IL 108997 A IL108997 A IL 108997A IL 10899794 A IL10899794 A IL 10899794A IL 108997 A IL108997 A IL 108997A
Authority
IL
Israel
Prior art keywords
carbon atoms
chain
straight
branched alkyl
denote
Prior art date
Application number
IL108997A
Other languages
English (en)
Other versions
IL108997A0 (en
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of IL108997A0 publication Critical patent/IL108997A0/xx
Publication of IL108997A publication Critical patent/IL108997A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/86—Carbazoles; Hydrogenated carbazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the ring system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
IL108997A 1993-03-18 1994-03-16 2-(4-heterotricyclically substituted methylphenyl)- cyclohexane-1- carboxylic acid derivatives, their preparation and pharmaceutical compositions containing them IL108997A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4308788A DE4308788A1 (de) 1993-03-18 1993-03-18 Hetero-tricyclisch-substituierte Phenyl-cyclohexan-carbonsäurederivate

Publications (2)

Publication Number Publication Date
IL108997A0 IL108997A0 (en) 1994-06-24
IL108997A true IL108997A (en) 1997-04-15

Family

ID=6483216

Family Applications (1)

Application Number Title Priority Date Filing Date
IL108997A IL108997A (en) 1993-03-18 1994-03-16 2-(4-heterotricyclically substituted methylphenyl)- cyclohexane-1- carboxylic acid derivatives, their preparation and pharmaceutical compositions containing them

Country Status (23)

Country Link
US (3) US5478836A (el)
EP (1) EP0617035B1 (el)
JP (1) JPH07165710A (el)
CN (1) CN1097756A (el)
AT (1) ATE160146T1 (el)
AU (1) AU670487B2 (el)
CA (1) CA2119095A1 (el)
CZ (1) CZ62494A3 (el)
DE (2) DE4308788A1 (el)
DK (1) DK0617035T3 (el)
ES (1) ES2109530T3 (el)
FI (1) FI941230A (el)
GR (1) GR3025817T3 (el)
HU (1) HU216829B (el)
IL (1) IL108997A (el)
NO (1) NO301826B1 (el)
NZ (1) NZ260096A (el)
PL (1) PL175560B1 (el)
RU (1) RU2125990C1 (el)
SI (1) SI0617035T1 (el)
SK (1) SK32194A3 (el)
TW (1) TW241264B (el)
ZA (1) ZA941878B (el)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2140722A1 (en) * 1994-01-24 1995-07-25 Joseph A. Jakubowski Beta-carboline thromboxane synthase inhibitors
US5550118A (en) * 1994-01-31 1996-08-27 Eli Lilly And Company Polyhydronorharman synthase inhibitors
DE4435477A1 (de) 1994-10-04 1996-04-11 Bayer Ag Cycloalkano-indol- und -azaindol-derivate
HRP960015B1 (en) * 1995-02-01 2000-12-31 Bayer Ag Substituted indole derivatives
DE19525028A1 (de) * 1995-07-10 1997-01-16 Bayer Ag Amide und Sulfonamide von heterocyclisch substituierten Benzylaminen
CA2284732C (en) * 1997-04-07 2008-06-17 Georgetown University Analogs of cocaine
US6221875B1 (en) 1998-04-02 2001-04-24 Neurogen Corporation Substituted 9H-pyridino [2,3-B]indole and 9H-pyrimidino [4,5-B]indole derivatives: selective neuropeptide Y receptor ligands
KR20040094866A (ko) * 2002-03-25 2004-11-10 이데미쓰 고산 가부시키가이샤 유기 전자발광 소자용 재료 및 이를 이용한 유기 전자발광소자
EP2318352B1 (en) * 2008-07-16 2012-12-19 Bristol-Myers Squibb Company Cyclohexenyl compounds as modulators of chemokine receptor activity

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH501623A (de) * 1967-12-18 1971-01-15 Ruetgerswerke Ag Verfahren zur Herstellung von 2-Chlorpyridin und seinen Derivaten
US4719211A (en) * 1984-05-01 1988-01-12 American Home Products Corporation 2,3,4,9-tetrahydro-2-heteroarylalkyl-1H-pyrido(3,4-B)indoles having antihypertensive properties
DE3535927A1 (de) * 1985-10-04 1987-04-09 Schering Ag 3-vinyl- und 3-ethinyl-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel
DE3535928A1 (de) * 1985-10-04 1987-04-09 Schering Ag Tetrahydro-(beta)-carboline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
GB8600651D0 (en) * 1986-01-11 1986-02-19 Beecham Group Plc Compounds
CA1334092C (en) * 1986-07-11 1995-01-24 David John Carini Angiotensin ii receptor blocking imidazoles
CA1338238C (en) * 1988-01-07 1996-04-09 David John Carini Angiotensin ii receptor blocking imidazoles and combinations thereof with diuretics and nsaids
IE64514B1 (en) * 1989-05-23 1995-08-09 Zeneca Ltd Azaindenes
GB8911854D0 (en) * 1989-05-23 1989-07-12 Ici Plc Heterocyclic compounds
US5164407A (en) * 1989-07-03 1992-11-17 Merck & Co., Inc. Substituted imidazo-fused 5-membered ring heterocycles and their use as angiotensin ii antagonsists
US5124335A (en) * 1991-01-30 1992-06-23 Merck & Co., Inc. Substituted pyrollo-fused 6 membered heterocycles as angiotensin ii antagonists
FR2672598A1 (fr) * 1991-02-11 1992-08-14 Adir Nouveaux inhibiteurs de n-myristoyltransferase, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
GB9109246D0 (en) * 1991-04-30 1991-06-19 Ici Plc Nitrogen derivatives
DE4118741A1 (de) * 1991-06-05 1992-12-10 Schering Ag Neue hetaryloxy-(beta)-carboline, deren herstellung und verwendung in arzneimitteln
US5212195A (en) * 1992-05-13 1993-05-18 Syntex (U.S.A.) Inc. Substituted indole antagonists derivatives which are angiotensin II
TW281667B (el) * 1994-02-03 1996-07-21 Synthelabo

Also Published As

Publication number Publication date
DE4308788A1 (de) 1994-09-22
NO301826B1 (no) 1997-12-15
US5708003A (en) 1998-01-13
IL108997A0 (en) 1994-06-24
FI941230A0 (fi) 1994-03-16
ES2109530T3 (es) 1998-01-16
HU216829B (hu) 1999-09-28
US5834481A (en) 1998-11-10
HU9400784D0 (en) 1994-06-28
CZ62494A3 (en) 1994-10-19
SK32194A3 (en) 1994-12-07
US5478836A (en) 1995-12-26
JPH07165710A (ja) 1995-06-27
RU2125990C1 (ru) 1999-02-10
CN1097756A (zh) 1995-01-25
EP0617035A1 (de) 1994-09-28
AU5788594A (en) 1994-09-22
TW241264B (el) 1995-02-21
ZA941878B (en) 1994-10-18
NZ260096A (en) 1996-02-27
PL175560B1 (pl) 1999-01-29
CA2119095A1 (en) 1994-09-19
SI0617035T1 (en) 1998-02-28
FI941230A (fi) 1994-09-19
GR3025817T3 (en) 1998-03-31
AU670487B2 (en) 1996-07-18
NO940966L (no) 1994-09-19
HUT67040A (en) 1995-01-30
NO940966D0 (no) 1994-03-17
DE59404557D1 (de) 1997-12-18
DK0617035T3 (da) 1998-07-27
ATE160146T1 (de) 1997-11-15
EP0617035B1 (de) 1997-11-12

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
RH Patent void