ES2106728T3 - Dihidroespirorenona como agente antiandrogeno. - Google Patents

Dihidroespirorenona como agente antiandrogeno.

Info

Publication number
ES2106728T3
ES2106728T3 ES90250127T ES90250127T ES2106728T3 ES 2106728 T3 ES2106728 T3 ES 2106728T3 ES 90250127 T ES90250127 T ES 90250127T ES 90250127 T ES90250127 T ES 90250127T ES 2106728 T3 ES2106728 T3 ES 2106728T3
Authority
ES
Spain
Prior art keywords
dihydrespirorenone
androgen agent
treatment
androgen
agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90250127T
Other languages
English (en)
Inventor
Sybille Dr Beier
Walter Dr Elger
Yukishige Dr Nishino
Rudolf Prof-Dr Wiechert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6380839&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2106728(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering AG filed Critical Schering AG
Application granted granted Critical
Publication of ES2106728T3 publication Critical patent/ES2106728T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Dental Preparations (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

EL INVENTO DESCRIBE LA APLICACION DE UN COMPUESTO DE FORMULA (I) JUNTO CON UN ESTROGENO, EN LA PRODUCCION DE MEDICAMENTOS APROPIADOS PARA EL TRATAMIENTO DE IRREGULARIDADES HORMONALES EN LA PREMENOPAUSIA (ESTABILIZACION DE CICLOS), DE TERAPIA DE SUSTITUCION HORMONAL EN DIFERENTES CLIMAS, PERTURBACIONES ANDROGENAS Y DE CONTRACEPCION.
ES90250127T 1989-05-16 1990-05-16 Dihidroespirorenona como agente antiandrogeno. Expired - Lifetime ES2106728T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3916112A DE3916112A1 (de) 1989-05-16 1989-05-16 Dihydrospirorenon als antiandrogen

Publications (1)

Publication Number Publication Date
ES2106728T3 true ES2106728T3 (es) 1997-11-16

Family

ID=6380839

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90250127T Expired - Lifetime ES2106728T3 (es) 1989-05-16 1990-05-16 Dihidroespirorenona como agente antiandrogeno.

Country Status (20)

Country Link
US (1) US5569652A (es)
EP (1) EP0398460B1 (es)
JP (1) JP2848919B2 (es)
CN (1) CN1033948C (es)
AT (1) ATE154881T1 (es)
AU (1) AU642876B2 (es)
BR (1) BR1101055A (es)
CA (1) CA2016780C (es)
DD (1) DD294417A5 (es)
DE (3) DE3916112A1 (es)
DK (1) DK0398460T3 (es)
ES (1) ES2106728T3 (es)
GR (1) GR3024861T3 (es)
HU (1) HU213408B (es)
IE (1) IE81143B1 (es)
IL (1) IL94416A (es)
LU (1) LU91065I2 (es)
NL (1) NL300221I2 (es)
PT (1) PT94038B (es)
ZA (1) ZA903754B (es)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4321957C2 (de) * 1993-07-01 1995-09-28 Marika Dr Med Ehrlich Verwendung eines hormonalen Mittels zur Therapie der Akne
DE4344462C2 (de) 1993-12-22 1996-02-01 Schering Ag Zusammensetzung für die Empfängnisverhütung
DE19651000A1 (de) * 1996-12-01 1998-06-04 Schering Ag Oxyiminopregnancarbolactone
SI1598069T1 (sl) * 1999-08-31 2009-10-31 Bayer Schering Pharma Ag Farmacevtska kombinacija etinilestradiola in drospirenona za uporabo kot kontracepitev
EP2305267A3 (en) 1999-08-31 2011-08-17 Bayer Schering Pharma Aktiengesellschaft Pharmaceutical combination of ethinylestradiol and drospirenone for use as a contraceptive
US6787531B1 (en) * 1999-08-31 2004-09-07 Schering Ag Pharmaceutical composition for use as a contraceptive
US20020132801A1 (en) * 2001-01-11 2002-09-19 Schering Aktiengesellschaft Drospirenone for hormone replacement therapy
AU2002222387A1 (en) * 2000-12-20 2002-07-01 Schering Aktiengesellschaft Cyclodextrin-drospirenone inclusion complexes
EP1216712A1 (en) * 2000-12-20 2002-06-26 Schering Aktiengesellschaft Cyclodextrin-drospirenone inclusion complexes
EP1216713A1 (en) 2000-12-20 2002-06-26 Schering Aktiengesellschaft Compositions of estrogen-cyclodextrin complexes
KR20040091141A (ko) * 2002-03-18 2004-10-27 파마시아 코포레이션 알도스테론 수용체 길항물질 및 니코틴산 또는 니코틴산유도체의 혼합물
PL373029A1 (en) * 2002-03-18 2005-08-08 Pharmacia Corporation Combination of an aldosterone receptor antagonist and a bile acid sequestering agent
WO2004070048A1 (en) * 2003-02-07 2004-08-19 Pharmacia & Upjohn Company Llc A microbial process to prepare 5-androsten-3beta, 7alpha, 15alpha-triol-17-one and related analogues
MY142989A (en) * 2004-03-10 2011-02-14 Bayer Schering Pharma Ag Stabilised supersaturated solids of lipophilic drugs
US20050220825A1 (en) * 2004-03-10 2005-10-06 Adrian Funke Molecular dispersions of drospirenone
KR20060130723A (ko) 2004-03-10 2006-12-19 쉐링 악티엔게젤샤프트 분자 분산된 드로스피레논을 포함하는 조성물
DE102004026679A1 (de) 2004-05-28 2005-12-15 Grünenthal GmbH Hormonales Kontrazeptivum enthaltend eine Kombination aus Ethinylestradiol und Chlormadinonacetat
DE102004026671A1 (de) * 2004-05-28 2005-12-15 Grünenthal GmbH Darreichungsform zur hormonalen Kontrazeption
DE102004026670A1 (de) 2004-05-28 2005-12-15 Grünenthal GmbH Hormonales Kontrazeptivum enthaltend eine Kombination aus Ethinylestradiol und Chlormadinonacetat
DE102004026669A1 (de) * 2004-05-28 2005-12-15 Grünenthal GmbH Verwendung einer Kombination aus Ethinylestradiol und Chlormadinonacetat zur Herstellung eines Arzneimittels
ITMI20042338A1 (it) * 2004-12-06 2005-03-06 Ind Chimica Srl Processo per la preparazione di drospirenone
US8475838B2 (en) * 2005-06-03 2013-07-02 Sandoz Ag Rapidly-dissolving pharmaceutical composition for inhibiting ovulation
SI1746101T2 (sl) 2005-07-21 2014-09-30 Bayer Pharma Aktiengesellschaft Postopek za pripravo 3-okso-pregn-4-en-21,17-karbolaktonov z oksidacijo 17-(3-hidroksipropil)-3,17-dihidroksiandrostanov brez uporabe kovine
US7319154B2 (en) 2005-07-21 2008-01-15 Bayer Schering Pharma Ag Process for the production of 3-oxo-pregn-4-ene-21, 17-carbolactones by the metal free oxidation of 17-(3-hydroxypropyl)-3, 17-dihydroxyandrostanes
US20070275941A1 (en) * 2006-05-17 2007-11-29 Vladimir Hanes Salt sensitivity and prevention of hypertension with drospirenone
US20090269403A1 (en) * 2008-04-24 2009-10-29 Shaked Ze Ev Oral contraceptive dosage forms and methods of making such dosage forms
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
ES2885523T3 (es) 2011-11-23 2021-12-14 Therapeuticsmd Inc Formulaciones y terapias de reposición hormonal de combinación naturales
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
MX2016014281A (es) 2014-05-22 2017-02-22 Therapeuticsmd Inc Formulaciones y terapias de reemplazo de combinación de hormonas naturales.
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
AU2017239645A1 (en) 2016-04-01 2018-10-18 Therapeuticsmd, Inc. Steroid hormone pharmaceutical composition
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2652761C2 (de) * 1976-11-16 1985-11-21 Schering AG, 1000 Berlin und 4709 Bergkamen 15,16-Methylen-Spirolactone, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
DE3022337A1 (de) * 1980-06-11 1982-01-07 Schering Ag Berlin Und Bergkamen, 1000 Berlin Praeparate zur kontrazeption und zur behandlung gynaekologischer stoerungen
US4347245A (en) * 1981-05-26 1982-08-31 German Shapiro Spironolactone-containing composition and use thereof
JPS59139400A (ja) * 1983-01-31 1984-08-10 Shionogi & Co Ltd 抗アルドステロン活性ステロイド誘導体
DE3402329A1 (de) * 1984-01-20 1985-08-01 Schering AG, 1000 Berlin und 4709 Bergkamen 6,6-ethylen-15,16-methylen-3-oxo-17(alpha)-pregn-4-en-21,17-carbolactone, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate
US4855289A (en) * 1984-06-04 1989-08-08 Wester Per O Combination of two active substances
US4729999A (en) * 1984-10-12 1988-03-08 Bcm Technologies Antiestrogen therapy for symptoms of estrogen deficiency
DE3615376A1 (de) * 1986-05-07 1987-11-12 Schering Ag 2,2;6,6-diethylen-3-oxo-17(alpha)-pregn-4-en-21,17-carbolactone, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate
IE61236B1 (en) * 1986-07-15 1994-10-19 American Home Prod Combination dosage form for pre-menopausal women

Also Published As

Publication number Publication date
IL94416A (en) 1997-07-13
CN1047299A (zh) 1990-11-28
HUT54500A (en) 1991-03-28
DE122004000006I1 (de) 2006-06-08
IE81143B1 (en) 2000-04-19
AU642876B2 (en) 1993-11-04
CA2016780A1 (en) 1990-11-16
PT94038B (pt) 1997-06-30
EP0398460B1 (de) 1997-07-02
BR1101055A (pt) 2000-08-08
CN1033948C (zh) 1997-02-05
US5569652A (en) 1996-10-29
EP0398460A3 (de) 1991-09-25
NL300221I1 (nl) 2006-04-03
LU91065I2 (fr) 2004-03-30
NL300221I2 (nl) 2006-11-01
HU903045D0 (en) 1990-09-28
DD294417A5 (de) 1991-10-02
JPH0395121A (ja) 1991-04-19
DE59010730D1 (de) 1997-08-07
HU213408B (en) 1997-06-30
CA2016780C (en) 2000-07-11
AU5509490A (en) 1990-11-22
IE901738L (en) 1990-11-16
EP0398460A2 (de) 1990-11-22
ZA903754B (en) 1991-02-27
ATE154881T1 (de) 1997-07-15
IL94416A0 (en) 1991-03-10
PT94038A (pt) 1991-01-08
DK0398460T3 (da) 1998-02-16
JP2848919B2 (ja) 1999-01-20
GR3024861T3 (en) 1998-01-30
DE3916112A1 (de) 1990-11-22
DE3916112C2 (es) 1992-04-30

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