ES2105852T3 - Procedimiento de preparacion de compuestos indolicos a partir de indolinas n-protegidas. - Google Patents
Procedimiento de preparacion de compuestos indolicos a partir de indolinas n-protegidas.Info
- Publication number
- ES2105852T3 ES2105852T3 ES95402267T ES95402267T ES2105852T3 ES 2105852 T3 ES2105852 T3 ES 2105852T3 ES 95402267 T ES95402267 T ES 95402267T ES 95402267 T ES95402267 T ES 95402267T ES 2105852 T3 ES2105852 T3 ES 2105852T3
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- protected
- indolines
- procedure
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PROCESO DE PREPARACION DE COMPUESTOS INDOLICOS EN UNA SOLA ETAPA, CARACTERIZADO POR EL HECHO DE QUE CONSISTE EN PONER EN CONTACTO, EN PRESENCIA DE UN CATALIZADOR DE HIDROGENACION, UNA INDOLINA N-PROTEGIDA DE FORMULA (I) EN LA QUE R{SUB,1} REPRESENTA UN RADICAL ALCENILO LINEAL O RAMIFICADO EN C{SUB,2-C{SUB,10} SUSTITUIDO O NO SUSTITUIDO O UN GRUPO BENCILO SUSTITUIDO O NO SUSTITUIDO, R{SUB,2,R{SUB,3},R{SUB,4} IDENTICOS O DIFERENTES REPRESENTAN UN ATOMO DEHIDROGENO,UN ATOMO DE HALOGENO TAL COMO EL BROMO EL CLORO EL FLUOR O ELINDOL,UN RADICAL ALQUILO EN C{SUB,1-7}ARILL, HIDROXILO, ALCOXI EN C{SUB,1-7}, LACENILOXI EN C{SUB,3-7}, ARILOXI, ACILOXI, FORMILO, AROILO, HIDROXIMETILO, ARIL.-HIROXIMETILO, CARBOXI, ALCOXICARBONILO C{SUB,1-7} CARBAMOPILO, AMINO, MONOALQUILO(C{SUB,1-7})AMINO, DIALQUILO(C{SUB,1-7})AMINO, ALCOXI(C{SUB,1.7})CARBONILAMINO, ACILAMINO, N-ALQUILO(C{SUB,1-7})ACILAMINO, DIALQUIL(C{SUB,17})FORMAMIDINO O DIALCOXI(C{SUB,1-7})METILO CON HIDROGENO O UN DONATE DE HIDROGENO, HACIENDOSE DICHA PUESTA EN CONTACTO BAJO LA AGITACION EN MEDIO SOLVENTE CON UN PH INFERIOR O IGUAL A 7 Y A UNA TEMPERATURA COMPRENDIDA ENTRE LA TEMPERATURA AMBIENTE Y LA DE REFLUJO DEL MEDIO DE REACCION, POR LO QUE SE OBTIENE UN COMPUESTO INDOLICO DE FORMULA (I) EN LA QUE R{SUB,2}, R{SUB,3}, R{SUB,4} TIEJEN LAS MISMAS SIGNIFICACIONES QUE EN LA FORMULA (I).
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9412892A FR2726269B1 (fr) | 1994-10-27 | 1994-10-27 | Procede de preparation de composes indoliques a partir d'indolines n-protegees |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2105852T3 true ES2105852T3 (es) | 1997-10-16 |
Family
ID=9468291
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES95402267T Expired - Lifetime ES2105852T3 (es) | 1994-10-27 | 1995-10-10 | Procedimiento de preparacion de compuestos indolicos a partir de indolinas n-protegidas. |
Country Status (8)
Country | Link |
---|---|
US (1) | US5578735A (es) |
EP (1) | EP0709374B1 (es) |
JP (1) | JP2661891B2 (es) |
AT (1) | ATE154597T1 (es) |
CA (1) | CA2161579C (es) |
DE (1) | DE69500368T2 (es) |
ES (1) | ES2105852T3 (es) |
FR (1) | FR2726269B1 (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3968731B2 (ja) * | 1997-04-07 | 2007-08-29 | イハラケミカル工業株式会社 | 5−メチルインドリン類の製造法 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2699532B1 (fr) * | 1992-12-18 | 1995-02-24 | Oreal | Nouveaux composés indolines, compositions tinctoriales à base de ces composés et procédé de teinture des fibres kératiniques. |
-
1994
- 1994-10-27 FR FR9412892A patent/FR2726269B1/fr not_active Expired - Fee Related
-
1995
- 1995-10-10 ES ES95402267T patent/ES2105852T3/es not_active Expired - Lifetime
- 1995-10-10 DE DE69500368T patent/DE69500368T2/de not_active Expired - Fee Related
- 1995-10-10 EP EP95402267A patent/EP0709374B1/fr not_active Expired - Lifetime
- 1995-10-10 AT AT95402267T patent/ATE154597T1/de active
- 1995-10-26 JP JP7279476A patent/JP2661891B2/ja not_active Expired - Fee Related
- 1995-10-26 US US08/547,732 patent/US5578735A/en not_active Expired - Fee Related
- 1995-10-27 CA CA002161579A patent/CA2161579C/fr not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JPH08225524A (ja) | 1996-09-03 |
EP0709374A1 (fr) | 1996-05-01 |
JP2661891B2 (ja) | 1997-10-08 |
ATE154597T1 (de) | 1997-07-15 |
EP0709374B1 (fr) | 1997-06-18 |
DE69500368T2 (de) | 1997-10-02 |
FR2726269A1 (fr) | 1996-05-03 |
US5578735A (en) | 1996-11-26 |
FR2726269B1 (fr) | 1996-12-13 |
CA2161579C (fr) | 2000-05-23 |
CA2161579A1 (fr) | 1996-04-28 |
DE69500368D1 (de) | 1997-07-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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