ES2103434T3 - Sintesis de acidos sulfonicos, cloruros de sulfonilo y sulfonamidas biciclicos y aromaticos. - Google Patents
Sintesis de acidos sulfonicos, cloruros de sulfonilo y sulfonamidas biciclicos y aromaticos.Info
- Publication number
- ES2103434T3 ES2103434T3 ES93306418T ES93306418T ES2103434T3 ES 2103434 T3 ES2103434 T3 ES 2103434T3 ES 93306418 T ES93306418 T ES 93306418T ES 93306418 T ES93306418 T ES 93306418T ES 2103434 T3 ES2103434 T3 ES 2103434T3
- Authority
- ES
- Spain
- Prior art keywords
- synthesis
- bicyclic aromatic
- bicyclic
- aromatic sulfonamides
- sulphonic acids
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000015572 biosynthetic process Effects 0.000 title abstract 3
- 229940124530 sulfonamide Drugs 0.000 title abstract 3
- 238000003786 synthesis reaction Methods 0.000 title abstract 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 title 1
- RAHZWNYVWXNFOC-UHFFFAOYSA-N Sulphur dioxide Chemical class O=S=O RAHZWNYVWXNFOC-UHFFFAOYSA-N 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
- 150000007513 acids Chemical class 0.000 title 1
- 150000003456 sulfonamides Chemical class 0.000 title 1
- -1 bicyclic aromatic sulfonic acids Chemical class 0.000 abstract 5
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical compound OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 abstract 1
- 229940100389 Sulfonylurea Drugs 0.000 abstract 1
- 238000005576 amination reaction Methods 0.000 abstract 1
- 238000005915 ammonolysis reaction Methods 0.000 abstract 1
- 239000012948 isocyanate Substances 0.000 abstract 1
- 150000002513 isocyanates Chemical class 0.000 abstract 1
- AFDQGRURHDVABZ-UHFFFAOYSA-N n,n-dimethylformamide;sulfur trioxide Chemical compound O=S(=O)=O.CN(C)C=O AFDQGRURHDVABZ-UHFFFAOYSA-N 0.000 abstract 1
- YCWSUKQGVSGXJO-NTUHNPAUSA-N nifuroxazide Chemical group C1=CC(O)=CC=C1C(=O)N\N=C\C1=CC=C([N+]([O-])=O)O1 YCWSUKQGVSGXJO-NTUHNPAUSA-N 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 150000003461 sulfonyl halides Chemical class 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Furan Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/932,404 US5387681A (en) | 1992-08-19 | 1992-08-19 | Synthesis of bicyclic aromatic sulfonic acids sulfonyl chlorides and sulfonamides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2103434T3 true ES2103434T3 (es) | 1997-09-16 |
Family
ID=25462254
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES93306418T Expired - Lifetime ES2103434T3 (es) | 1992-08-19 | 1993-08-13 | Sintesis de acidos sulfonicos, cloruros de sulfonilo y sulfonamidas biciclicos y aromaticos. |
Country Status (15)
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6140505A (en) * | 1995-03-10 | 2000-10-31 | G. D. Searle & Co. | Synthesis of benzo fused heterocyclic sulfonyl chlorides |
| CA2267998A1 (en) * | 1996-10-04 | 1998-04-09 | Eli Lilly And Company | Antitumor compositions and methods of treatment |
| US8829198B2 (en) * | 2007-10-31 | 2014-09-09 | Proteotech Inc | Compounds, compositions and methods for the treatment of beta-amyloid diseases and synucleinopathies |
| US20090227647A1 (en) * | 2008-03-05 | 2009-09-10 | Thomas Lake | Compounds, Compositions and Methods for the Treatment of Islet Amyloid Polypeptide (IAPP) Accumulation in Diabetes |
| US8916598B2 (en) | 2003-05-30 | 2014-12-23 | Proteotech Inc | Compounds, compositions, and methods for the treatment of β-amyloid diseases and synucleinopathies |
| US20100331380A1 (en) * | 2009-06-29 | 2010-12-30 | Esposito Luke A | Compounds, Compositions, and Methods for the Treatment of Beta-Amyloid Diseases and Synucleinopathies |
| EP1640372B1 (en) * | 2003-06-25 | 2012-08-01 | Nissan Chemical Industries, Ltd. | 1,4-benzodioxane sulfonic acid compound and use thereof as electron-acceptor material |
| EP2422780A1 (en) | 2004-05-07 | 2012-02-29 | Sequoia Pharmaceuticals, Inc. | Resistance-repellent retroviral protease inhibitors |
| BRPI0821247A2 (pt) | 2007-12-14 | 2015-06-16 | Univ Georgetown | Inibidores de histona deacetilase |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH368076A (fr) * | 1961-02-24 | 1963-03-15 | Mefina Sa | Fusée pour projectile |
| DE3419795A1 (de) * | 1984-05-26 | 1985-11-28 | Basf Ag, 6700 Ludwigshafen | Verfahren zur herstellung von acyloxybenzolsulfonsaeuren und ihrer alkali- und erdalkalisalze |
| US4845128A (en) * | 1984-06-27 | 1989-07-04 | Eli Lilly And Company | N([(4-trifluoromethylphenyl)amino]carbonyl)benzene sulfonamides |
| JPS6163671A (ja) * | 1984-09-05 | 1986-04-01 | Shionogi & Co Ltd | ２，３−ジヒドロベンゾフラン−５−スルホンアミド誘導体および降圧利尿剤 |
| US4560771A (en) * | 1984-10-01 | 1985-12-24 | Ciba Geigy Corporation | Process for the preparation of 1,2-benzoxathiines |
| IL83215A (en) * | 1986-07-23 | 1991-12-15 | Lilly Co Eli | Synthesis of bicyclic heteroaromatic sulfonyl chlorides |
| JPH01100164A (ja) * | 1987-10-12 | 1989-04-18 | Shionogi & Co Ltd | スルファモイル−２−ベンゾフランカルボン酸誘導体 |
| ZA915371B (en) * | 1990-07-17 | 1993-03-31 | Lilly Co Eli | Antitumor compositions and methods of treatment |
| JP5015452B2 (ja) * | 2005-12-27 | 2012-08-29 | 京セラ株式会社 | セルスタック装置及び燃料電池 |
| JP6213893B2 (ja) * | 2012-09-25 | 2017-10-18 | Toto株式会社 | 固体酸化物型燃料電池装置 |
| JP2014143162A (ja) * | 2012-12-26 | 2014-08-07 | Kyocera Corp | セルスタック装置および燃料電池装置 |
-
1992
- 1992-08-19 US US07/932,404 patent/US5387681A/en not_active Expired - Fee Related
-
1993
- 1993-07-30 BR BR9303223A patent/BR9303223A/pt not_active Application Discontinuation
- 1993-08-12 CA CA002103930A patent/CA2103930A1/en not_active Abandoned
- 1993-08-12 TW TW082106453A patent/TW232688B/zh active
- 1993-08-12 IL IL11948093A patent/IL119480A/xx not_active IP Right Cessation
- 1993-08-12 IL IL10666993A patent/IL106669A/en not_active IP Right Cessation
- 1993-08-13 AT AT93306418T patent/ATE153333T1/de not_active IP Right Cessation
- 1993-08-13 DE DE69310836T patent/DE69310836T2/de not_active Expired - Fee Related
- 1993-08-13 DK DK93306418.0T patent/DK0583960T3/da active
- 1993-08-13 JP JP20152593A patent/JP3162232B2/ja not_active Expired - Fee Related
- 1993-08-13 ES ES93306418T patent/ES2103434T3/es not_active Expired - Lifetime
- 1993-08-13 EP EP93306418A patent/EP0583960B1/en not_active Expired - Lifetime
- 1993-08-16 MX MX9304960A patent/MX9304960A/es not_active IP Right Cessation
- 1993-08-17 HU HU9302363A patent/HU219235B/hu not_active IP Right Cessation
- 1993-08-18 KR KR1019930016042A patent/KR100261824B1/ko not_active Expired - Fee Related
-
1996
- 1996-10-24 IL IL11948096A patent/IL119480A0/xx unknown
-
1997
- 1997-07-16 GR GR970401771T patent/GR3024121T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL106669A (en) | 1999-12-31 |
| EP0583960B1 (en) | 1997-05-21 |
| EP0583960A3 (en) | 1994-06-15 |
| IL106669A0 (en) | 1993-12-08 |
| HU219235B (en) | 2001-03-28 |
| KR940003948A (ko) | 1994-03-14 |
| EP0583960A2 (en) | 1994-02-23 |
| CA2103930A1 (en) | 1994-02-20 |
| DE69310836T2 (de) | 1997-10-09 |
| HUT64953A (en) | 1994-03-28 |
| BR9303223A (pt) | 1994-03-01 |
| TW232688B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1994-10-21 |
| HU9302363D0 (en) | 1993-10-28 |
| JPH06199825A (ja) | 1994-07-19 |
| IL119480A0 (en) | 1997-01-10 |
| KR100261824B1 (ko) | 2000-07-15 |
| MX9304960A (es) | 1994-05-31 |
| GR3024121T3 (en) | 1997-10-31 |
| DE69310836D1 (de) | 1997-06-26 |
| US5387681A (en) | 1995-02-07 |
| IL119480A (en) | 1999-12-22 |
| ATE153333T1 (de) | 1997-06-15 |
| DK0583960T3 (da) | 1997-08-25 |
| JP3162232B2 (ja) | 2001-04-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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