ES2101306T3 - Procedimiento para la obtencion de vitamina e. - Google Patents
Procedimiento para la obtencion de vitamina e.Info
- Publication number
- ES2101306T3 ES2101306T3 ES93906485T ES93906485T ES2101306T3 ES 2101306 T3 ES2101306 T3 ES 2101306T3 ES 93906485 T ES93906485 T ES 93906485T ES 93906485 T ES93906485 T ES 93906485T ES 2101306 T3 ES2101306 T3 ES 2101306T3
- Authority
- ES
- Spain
- Prior art keywords
- acid
- procedure
- mixture
- transformation
- obtaining vitamin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 229940088594 vitamin Drugs 0.000 title 1
- 229930003231 vitamin Natural products 0.000 title 1
- 235000013343 vitamin Nutrition 0.000 title 1
- 239000011782 vitamin Substances 0.000 title 1
- 150000003722 vitamin derivatives Chemical class 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 3
- WFDIJRYMOXRFFG-UHFFFAOYSA-N Acetic anhydride Chemical compound CC(=O)OC(C)=O WFDIJRYMOXRFFG-UHFFFAOYSA-N 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 230000009466 transformation Effects 0.000 abstract 2
- PLIKAWJENQZMHA-UHFFFAOYSA-N 4-aminophenol Chemical compound NC1=CC=C(O)C=C1 PLIKAWJENQZMHA-UHFFFAOYSA-N 0.000 abstract 1
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 abstract 1
- 229960002645 boric acid Drugs 0.000 abstract 1
- 235000010338 boric acid Nutrition 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
- C07D311/72—3,4-Dihydro derivatives having in position 2 at least one methyl radical and in position 6 one oxygen atom, e.g. tocopherols
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyrane Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PROCESO PARA LA ELABORACION DE DL-ALFA-TOCOFEROL O DL-ALFAACETATO TOCOFERIL A TRAVES DE TRANSFORMACION CATALIZADA ACIDA DE 2,3,5 TRIMETILHIDROQUINONA (TMH) CON CITOL O ISOCITOL EN UN DISOLVENTE EN TEMPERATURA ELEVADA Y EVENTUALMENTE ESTERIFICACION A CONTINUACION DEL TOCOFEROL OBTENIDO CON ACETANHIDRIDO, QUE ESTA CARACTERIZADO, PORQUE LA TRANSFORMACION SE REALIZA EN PRESENCIA DE UNA MEZCLA DE ACIDO ORTOBORICO Y ACIDOS DI O TRICARBOXILICIOS ALIFATICOS DETERMINADOS, CON PREFERENCIA EN PRESENCIA DE UNA MEZCLA DE ACIDO ORTOBORICO Y ACIDO AXALICO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4208477A DE4208477A1 (de) | 1992-03-17 | 1992-03-17 | Verfahren zur herstellung von vitamin e |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2101306T3 true ES2101306T3 (es) | 1997-07-01 |
Family
ID=6454252
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES93906485T Expired - Lifetime ES2101306T3 (es) | 1992-03-17 | 1993-03-05 | Procedimiento para la obtencion de vitamina e. |
Country Status (10)
Country | Link |
---|---|
US (1) | US5468883A (es) |
EP (1) | EP0631577B1 (es) |
JP (1) | JP2550288B2 (es) |
CA (1) | CA2091729C (es) |
CZ (1) | CZ281829B6 (es) |
DE (2) | DE4208477A1 (es) |
ES (1) | ES2101306T3 (es) |
HU (1) | HU214095B (es) |
SK (1) | SK112094A3 (es) |
WO (1) | WO1993019057A1 (es) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3416281B2 (ja) * | 1994-04-12 | 2003-06-16 | エーザイ株式会社 | α−トコフェロール誘導体の製造方法および触媒 |
US5663376A (en) † | 1994-07-27 | 1997-09-02 | Eisai Co., Ltd. | Process for the preparation of α-tocopherol |
DE19524928A1 (de) * | 1995-07-08 | 1997-01-09 | Basf Ag | Verfahren zur Rektifikation von Gemischen hochsiedender luft- und/oder temperaturempfindlicher Substanzen, die eine hohe Trennleistung erfordern, im Feinvakuum, sowie für dieses Verfahren geeignete Kolonnen |
US5886196A (en) * | 1996-01-12 | 1999-03-23 | Roche Vitamins Inc. | Method of catalyzing condensation reactions |
DE10011403A1 (de) * | 2000-03-09 | 2001-09-13 | Degussa | Verfahren zur Herstellung von alpha-Tocopherolacetat durch Kondensation von Trimethylhydrochinon mit Isophytol unter Recyclierung einer essigsauren Katalysatorlösung |
AU2002227934A1 (en) | 2000-11-22 | 2002-06-03 | Basf Aktiengesellschaft | Method for continuously acylating chromanol ester derivatives |
DE10135714A1 (de) * | 2001-07-21 | 2003-02-06 | Basf Ag | Verbessertes Verfahren zur Aufarbeitung eines Vitamin-E-Acetat-haltigen Produktstromes |
US7858813B2 (en) | 2004-08-19 | 2010-12-28 | Dsm Ip Assets B.V. | Process for the rectification of mixtures of high-boiling air-and/or temperature-sensitive useful products |
WO2006018310A2 (en) * | 2004-08-19 | 2006-02-23 | Dsm Ip Assets B.V. | Process for the working-up of a vitamin e- and vitamin e-acetate and rectification colum suitable therefore |
DE102005013103A1 (de) | 2005-03-18 | 2006-09-28 | Sms Demag Ag | Kontrollierte Dickenreduktion bei schmelztauchbeschichtetem warmgewalztem Stahlband und hierbei eingesetzte Anlage |
CN106478581A (zh) * | 2016-08-30 | 2017-03-08 | 芜湖华海生物工程有限公司 | 一种维生素e醋酸酯的制备方法 |
CN113083339B (zh) * | 2021-04-15 | 2022-11-08 | 万华化学(四川)有限公司 | 一种用于制备维生素e的催化剂及其制备方法和应用 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3459773A (en) * | 1966-12-27 | 1969-08-05 | Takasago Perfumery Co Ltd | Process for producing alpha-tocopherol and its esters |
US3708505A (en) * | 1971-02-25 | 1973-01-02 | Diamond Shamrock Corp | Process for preparation of d,l-alpha tocopherol |
BE810299A (fr) * | 1974-01-29 | 1974-05-16 | Procede de fabrication de composes contenant un noyau chromane. | |
US4217285A (en) * | 1976-09-29 | 1980-08-12 | Nisshin Flour Milling Co., Ltd. | Process for the preparation of Dl-α-tocopherol of high purity |
JPS6019309B2 (ja) * | 1976-09-29 | 1985-05-15 | 日清製粉株式会社 | 高純度dl−α−トコフエロ−ルの製造法 |
DE3367100D1 (en) * | 1982-07-29 | 1986-11-27 | Basf Wyandotte Corp | Alpha tocopherol process |
-
1992
- 1992-03-17 DE DE4208477A patent/DE4208477A1/de not_active Withdrawn
-
1993
- 1993-03-05 DE DE59306604T patent/DE59306604D1/de not_active Expired - Fee Related
- 1993-03-05 WO PCT/EP1993/000498 patent/WO1993019057A1/de active IP Right Grant
- 1993-03-05 ES ES93906485T patent/ES2101306T3/es not_active Expired - Lifetime
- 1993-03-05 JP JP5516203A patent/JP2550288B2/ja not_active Expired - Lifetime
- 1993-03-05 CZ CZ942250A patent/CZ281829B6/cs not_active IP Right Cessation
- 1993-03-05 US US08/302,743 patent/US5468883A/en not_active Expired - Fee Related
- 1993-03-05 EP EP93906485A patent/EP0631577B1/de not_active Expired - Lifetime
- 1993-03-05 SK SK1120-94A patent/SK112094A3/sk unknown
- 1993-03-05 HU HU9402669A patent/HU214095B/hu not_active IP Right Cessation
- 1993-03-16 CA CA002091729A patent/CA2091729C/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
HU214095B (hu) | 1998-03-02 |
US5468883A (en) | 1995-11-21 |
DE4208477A1 (de) | 1993-09-23 |
EP0631577B1 (de) | 1997-05-28 |
CZ281829B6 (cs) | 1997-02-12 |
SK112094A3 (en) | 1995-04-12 |
CA2091729C (en) | 1999-11-23 |
WO1993019057A1 (de) | 1993-09-30 |
HU9402669D0 (en) | 1995-02-28 |
JPH07507274A (ja) | 1995-08-10 |
JP2550288B2 (ja) | 1996-11-06 |
HUT71257A (en) | 1995-11-28 |
CA2091729A1 (en) | 1993-09-18 |
DE59306604D1 (de) | 1997-07-03 |
CZ225094A3 (en) | 1995-04-12 |
EP0631577A1 (de) | 1995-01-04 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2101306T3 (es) | Procedimiento para la obtencion de vitamina e. | |
ES2083881T3 (es) | Procedimiento para la preparacion de agentes tensioactivos anfoteros. | |
ES2057090T3 (es) | Un procedimiento para la preparacion de sulfonatos de olefinas internas. | |
ES2058888T3 (es) | Procedimientos que utilizan composiciones de catalizador de fluoruro de aluminio para preparar haloetanos que contienen fluor. | |
ES2124373T3 (es) | Procedimiento para la preparacion de derivados del acido n-acil-n,n',n'-etilendiamintriacetico. | |
EP0257549A3 (en) | An improved cryogenic, forced -convection, freezing system | |
IT8722030A0 (it) | Procedimento di frazionamento di miscele gassose idrocarburiche ad alto contenuto di gas acidi. | |
EP0729934A3 (en) | Process for the preparation of 3-alkoxy-2-substituted benzoic acid or its ester | |
CO4560577A1 (es) | Proceso para oligomerizar olefinas | |
ES2088973T3 (es) | Cloracion mejorada de 6-esteres de sacarosa. | |
ES2109391T3 (es) | Soporte de ensayo para la determinacion de analitos y procedimiento para su fabricacion. | |
ES2146268T3 (es) | Procedimiento para la fabricacion de acido amidoetercarboxilico o de una sal del mismo y de una mezcla de agentes con actividad superficial que los contienen. | |
EP1163906A3 (en) | Method for stabilizing pranoprofen and stable liquid preparation of pranoprofen | |
ES2123671T3 (es) | Inhibidor de descomposicion de un hidrofluorocarbono y procedimiento. | |
BR0014577A (pt) | Método e sistema para refrigerar e efetuar mudança no estado de uma mistura lìquida | |
MX166927B (es) | Conversion de compuestos de calcio a compuestos solidos y gaseosos | |
ES2109555T3 (es) | Procedimiento para la obtencion de carbonatos de arilo. | |
AU1931992A (en) | Method of making post-foaming gels | |
JPS5417744A (en) | Linear lighting method | |
ES2035452T3 (es) | Procedimiento para la obtencion conjunta de 3-dialquil-aminopropionitrilos, bis-(2-cianoetil)-eteres y en caso deseado etilencianhidrina. | |
ES2096969T3 (es) | Procedimiento para la obtencion de difluormetoxi- y difluormetiltioarenos. | |
PT84044A (pt) | Processo e aparelho para a liquefaccao de material fundivel tal como vidro | |
DE3360629D1 (en) | Organic solution for phosphating metal surfaces | |
ES2075110T3 (es) | Un metodo para producir 3'-(1h-tetrazol-5-il) oxanilato de butilo. | |
ES2105453T3 (es) | Procedimiento para la preparacion de acido 5-fluoro-antranilico. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
Ref document number: 631577 Country of ref document: ES |