ES2095183B1 - Composiciones acusosas gelificantes para la administracion intranasal de farmacos. - Google Patents

Composiciones acusosas gelificantes para la administracion intranasal de farmacos.

Info

Publication number
ES2095183B1
ES2095183B1 ES9401412A ES9401412A ES2095183B1 ES 2095183 B1 ES2095183 B1 ES 2095183B1 ES 9401412 A ES9401412 A ES 9401412A ES 9401412 A ES9401412 A ES 9401412A ES 2095183 B1 ES2095183 B1 ES 2095183B1
Authority
ES
Spain
Prior art keywords
intranasal administration
pharmaces
compositions
gelificing
acususing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES9401412A
Other languages
English (en)
Other versions
ES2095183A1 (es
Inventor
Carreras Manuel Roig
Vidal Carlos Monserrat
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratorios Salvat SA
Original Assignee
Laboratorios Salvat SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios Salvat SA filed Critical Laboratorios Salvat SA
Priority to ES9401412A priority Critical patent/ES2095183B1/es
Publication of ES2095183A1 publication Critical patent/ES2095183A1/es
Application granted granted Critical
Publication of ES2095183B1 publication Critical patent/ES2095183B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

"COMPOSICIONES ACUOSAS GELIFICANTES PARA LA ADMINISTRACION INTRANASAL DE FARMACOS". COMPOSICIONES ACUOSAS LIQUIDAS A TEMPERATURA AMBIENTE, QUE FORMAN UN GEL A LA TEMPERATURA DEL CUERPO HUMANO, Y QUE SE ADHIEREN A LA MUCOSA NASAL, CARACTERIZADAS PORQUE COMPRENDEN UN 8-12% DE UN POLOXAMERO DE PESO MOLECULAR 8.000-10.000 DALTONS; UN 1% DE ALCOHOL BENCILICO; UNA CANTIDAD MENOR DE 1% DE UN POLIMERO BIOADHESIVO SELECCIONADO ENTRE CARBOXIPOLIMETILENO, HIDROXIPROPILCELULOSA, HIDROXIPROPILMETILCELULOSA Y EL GRUPO DE POLIMEROS ENTRECRUZADOS DERIVADOS DEL ACIDO ACRILICO; Y UNA CANTIDAD DE DISOLUCION ACUOSA DE CLORURO SODICO ADECUADA PARA CONSEGUIR UNA DISOLUCION FINAL PRACTICAMENTE ISOTONICA. TIENEN APLICACION EN LA ADMINISTRACION INTRANASAL DE PRINCIPIOS ACTIVOS FARMACEUTICOS, ESPECIALMENTE DE AGENTES SIMPATOMIMETICOS COMO LA OXIMETAZOLINA, CON LAS VENTAJAS DE UNA MEJOR BIODISPONIBILIDAD Y UNA LIBERACION CONTROLADA, QUE DISMINUYEN EL RIESGO POR EFECTOS SECUNDARIOS ADVERSOS.
ES9401412A 1994-06-29 1994-06-29 Composiciones acusosas gelificantes para la administracion intranasal de farmacos. Expired - Fee Related ES2095183B1 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES9401412A ES2095183B1 (es) 1994-06-29 1994-06-29 Composiciones acusosas gelificantes para la administracion intranasal de farmacos.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9401412A ES2095183B1 (es) 1994-06-29 1994-06-29 Composiciones acusosas gelificantes para la administracion intranasal de farmacos.

Publications (2)

Publication Number Publication Date
ES2095183A1 ES2095183A1 (es) 1997-02-01
ES2095183B1 true ES2095183B1 (es) 1997-12-16

Family

ID=8286732

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9401412A Expired - Fee Related ES2095183B1 (es) 1994-06-29 1994-06-29 Composiciones acusosas gelificantes para la administracion intranasal de farmacos.

Country Status (1)

Country Link
ES (1) ES2095183B1 (es)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8476319B2 (en) 2005-03-10 2013-07-02 3M Innovative Properties Company Methods of treating ear infections
US8512723B2 (en) 2003-09-09 2013-08-20 3M Innovative Properties Company Antimicrobial compositions and methods

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2006223136A1 (en) 2005-03-10 2006-09-21 3M Innovative Properties Company Antimicrobial compositions comprising esters of hydroxycarboxylic acids
BRPI0608690B8 (pt) 2005-03-10 2021-05-25 3M Innovative Properties Co uso de uma composição antimicrobiana
DE102009008094A1 (de) 2009-02-09 2010-08-19 Barnikol-Keuten, Doris, Dr. In situ Haft-Gelbildende Zubereitungen, insbesondere zur topischen Anwendung auf befeuchtete Haut/Schleimhaut
PL2759290T3 (pl) 2013-01-24 2020-03-31 Merz Pharma Gmbh & Co. Kgaa Płynny preparat w aerozolu do stosowania donosowego z wydłużonym miejscowym czasem działania
DE102013001151A1 (de) 2013-01-24 2014-07-24 Merz Pharma Gmbh & Co. Kgaa Sprühbare flüssige Zubereitung zur insbesondere nasalen Anwendung mit erhöhter lokaler Verweilzeit
DE202013000748U1 (de) 2013-01-24 2013-02-19 Merz Pharma Gmbh & Co. Kgaa Sprühbare flüssige Zubereitung zur insbesondere nasalen Anwendung mit erhöhter lokaler Verweilzeit

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4534958A (en) * 1983-07-13 1985-08-13 Basf Wyandotte Corporation Aerosol gel
CA1291036C (en) * 1986-04-23 1991-10-22 Edwin I. Stoltz Nasal administration of drugs
IT1250691B (it) * 1991-07-22 1995-04-21 Giancarlo Santus Composizioni terapeutiche per somministrazione intranasale comprendenti ketorolac.

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8512723B2 (en) 2003-09-09 2013-08-20 3M Innovative Properties Company Antimicrobial compositions and methods
US8476319B2 (en) 2005-03-10 2013-07-02 3M Innovative Properties Company Methods of treating ear infections

Also Published As

Publication number Publication date
ES2095183A1 (es) 1997-02-01

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