ES2094690A1 - Nuevos derivados de imida-piperazinas. - Google Patents
Nuevos derivados de imida-piperazinas.Info
- Publication number
- ES2094690A1 ES2094690A1 ES09402396A ES9402396A ES2094690A1 ES 2094690 A1 ES2094690 A1 ES 2094690A1 ES 09402396 A ES09402396 A ES 09402396A ES 9402396 A ES9402396 A ES 9402396A ES 2094690 A1 ES2094690 A1 ES 2094690A1
- Authority
- ES
- Spain
- Prior art keywords
- new
- imido
- piperazine derivatives
- treatment
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NUEVOS DERIVADOS DE IMIDA-PIPERAZINAS. LA PRESENTE INVENCION TRATA DE NUEVOS COMPUESTOS DE FORMULA I, DONDE R1 Y R2 SON FENILOS O BIFENIL-2,2-DIILO; N ES IGUAL A 1, 2, 3 O 4; R3 ES HIDROGENO, ALQUILO, HALOGENO, TRIFLUOROMETILO O ALCOXI. SE DESCRIBEN LOS DIFERENTES METODOS ALTERNATIVOS DE PREPARACION DE DICHOS COMPUESTOS, LOS CUALES PRESENTAN ELEVADA AFINIDAD Y SELECTIVIDAD POR EL RECEPTOR SEROTONINERGICO 5-HT1A Y ADRENERGICO AL1, LO QUE INDICA SU UTILIDAD DESDE EL PUNTO DE VISTA TERAPEUTICO EN EL TRATAMIENTO DE TRASTORNOS EN EL SNC (TALES COMO LA ANSIEDAD Y DEPRESION), ASI COMO EN EL TRATAMIENTO DE LA HIPERTENSION.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9402396A ES2094690B1 (es) | 1994-11-22 | 1994-11-22 | Nuevos derivados de imida-piperazinas. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9402396A ES2094690B1 (es) | 1994-11-22 | 1994-11-22 | Nuevos derivados de imida-piperazinas. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2094690A1 true ES2094690A1 (es) | 1997-01-16 |
ES2094690B1 ES2094690B1 (es) | 1997-08-01 |
Family
ID=8288052
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES9402396A Expired - Fee Related ES2094690B1 (es) | 1994-11-22 | 1994-11-22 | Nuevos derivados de imida-piperazinas. |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES2094690B1 (es) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000005206A1 (en) * | 1998-07-21 | 2000-02-03 | Ranbaxy Laboratories Limited | Arylpiperazine derivatives useful as uro-selective alpha-1-adrenoceptor blockers |
WO2000005205A1 (en) * | 1998-07-21 | 2000-02-03 | Ranbaxy Laboratories Limited | Arylpiperazine derivatives useful as uroselective alpha1-adrenoceptor blockers |
ES2154605A1 (es) * | 1999-09-14 | 2001-04-01 | Univ Madrid Complutense | Nuevos derivados mixtos de bencimidazol-arilpiperazina con afinidad por los receptores serotoninergicos 5-ht1a y 5-ht3 |
WO2005021506A1 (en) * | 2003-08-28 | 2005-03-10 | Ranbaxy Laboratories Limited | Synthesis of 1-[4-(2-methoxyphenyl) piperazin-1-yl]-3-(2,6-dioxopiperidin-1-yl) propane |
US7351732B2 (en) | 2002-07-31 | 2008-04-01 | Schwarz Pharma S.L. | Cycloalkanedione derivatives, method for the production thereof and their pharmacological applications |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0082402A2 (en) * | 1981-12-22 | 1983-06-29 | Sumitomo Chemical Company, Limited | Succinimide derivates and process for preparation thereof |
EP0109562A1 (en) * | 1982-10-21 | 1984-05-30 | Sumitomo Chemical Company, Limited | Succinimide derivatives and their production |
-
1994
- 1994-11-22 ES ES9402396A patent/ES2094690B1/es not_active Expired - Fee Related
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0082402A2 (en) * | 1981-12-22 | 1983-06-29 | Sumitomo Chemical Company, Limited | Succinimide derivates and process for preparation thereof |
EP0109562A1 (en) * | 1982-10-21 | 1984-05-30 | Sumitomo Chemical Company, Limited | Succinimide derivatives and their production |
Non-Patent Citations (2)
Title |
---|
MOKROSZ, M.J. y col. 1-(2-METHOXIPHENYL)-4-(4-SUCCINIMIDO)BUTYL)PIPERAZINE (MM-77): A NEW, POTENT, POSTSYNAPTIC ANTAGONIST OF 5-HT1A RECEPTORS. Medical Chemistry Research, 1994, Vol. 4, pßginas 161-169 * Estructura 9 * * |
YEVICH, J.P. y col. Buspirone Analogues. 1. Structure-Activity Relationships in a Series of N-Aryl- and Heteroarylpiperazine Derivatives. J. Med. Chem. 1983, Vol. 26, N‘ 2, pßginas 194-203 * Ejemplos 22,23,25,26,28,29 * * |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000005206A1 (en) * | 1998-07-21 | 2000-02-03 | Ranbaxy Laboratories Limited | Arylpiperazine derivatives useful as uro-selective alpha-1-adrenoceptor blockers |
WO2000005205A1 (en) * | 1998-07-21 | 2000-02-03 | Ranbaxy Laboratories Limited | Arylpiperazine derivatives useful as uroselective alpha1-adrenoceptor blockers |
ES2154605A1 (es) * | 1999-09-14 | 2001-04-01 | Univ Madrid Complutense | Nuevos derivados mixtos de bencimidazol-arilpiperazina con afinidad por los receptores serotoninergicos 5-ht1a y 5-ht3 |
US7351732B2 (en) | 2002-07-31 | 2008-04-01 | Schwarz Pharma S.L. | Cycloalkanedione derivatives, method for the production thereof and their pharmacological applications |
WO2005021506A1 (en) * | 2003-08-28 | 2005-03-10 | Ranbaxy Laboratories Limited | Synthesis of 1-[4-(2-methoxyphenyl) piperazin-1-yl]-3-(2,6-dioxopiperidin-1-yl) propane |
Also Published As
Publication number | Publication date |
---|---|
ES2094690B1 (es) | 1997-08-01 |
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Legal Events
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EC2A | Search report published |
Date of ref document: 19970116 Kind code of ref document: A1 Effective date: 19970116 |
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FD2A | Announcement of lapse in spain |
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