ES2095811A1 - Nuevos derivados de arilpiperazinas. - Google Patents

Nuevos derivados de arilpiperazinas.

Info

Publication number
ES2095811A1
ES2095811A1 ES09501534A ES9501534A ES2095811A1 ES 2095811 A1 ES2095811 A1 ES 2095811A1 ES 09501534 A ES09501534 A ES 09501534A ES 9501534 A ES9501534 A ES 9501534A ES 2095811 A1 ES2095811 A1 ES 2095811A1
Authority
ES
Spain
Prior art keywords
new
dihydro
arylpiperazine derivatives
compounds
alkoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES09501534A
Other languages
English (en)
Other versions
ES2095811B1 (es
Inventor
Rodriguez Maria Luz Lopez
Samitier Maria Luisa Rosado
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universidad Complutense de Madrid
Original Assignee
Universidad Complutense de Madrid
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universidad Complutense de Madrid filed Critical Universidad Complutense de Madrid
Priority to AU30792/95A priority Critical patent/AU3079295A/en
Priority to ES9501534A priority patent/ES2095811B1/es
Priority to PCT/ES1995/000094 priority patent/WO1996006846A1/es
Publication of ES2095811A1 publication Critical patent/ES2095811A1/es
Application granted granted Critical
Publication of ES2095811B1 publication Critical patent/ES2095811B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

NUEVOS DERIVADOS DE ARILPIPERAZINAS. LA PRESENTE INVENCION TRATA DE NUEVOS COMPUESTOS DE FORMULA GENERAL I, DONDE X ES -(CH2)3- O -(CH2)4-; M ES IGUAL A 0 O 1; N ES IGUAL A 1, 2, 3 O 4; AR ES 1-NAFTILO, 7-BENZOFURANILO, 2,3-DIHIDRO-1,4-BENZODIOXAN-5-ILO, 3,4-DIHIDRO-2H-1,5-BENZODIOXEPIN-6-ILO, FENILO O FENILO SUSTITUIDO POR ALQUILO, HALOGENO, TRIFLUOROMETILO, NITRO, CIANO, ALCOXI, AMINO, ALQUILCARBAMOILO ALQUILSULFONAMIDO O ALCOXICARBONILO. SE DESCRIBEN LOS DIFERENTES METODOS ALTERNATIVOS DE PREPARACION DE DICHOS COMPUESTOS, LOS CUALES PRESENTAN AFINIDAD POR EL RECEPTOR SEROTONINERGICO 5-HT1A, LO QUE INDICA SU UTILIDAD DESDE EL PUNTO DE VISTA TERAPEUTICO EN EL TRATAMIENTO DE TRASTORNOS EN EL SNC, TALES COMO LA ANSIEDAD Y DEPRESION.
ES9501534A 1994-09-01 1995-07-28 Nuevos derivados de arilpiperazinas. Expired - Fee Related ES2095811B1 (es)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU30792/95A AU3079295A (en) 1994-09-01 1995-07-28 New arylpiperazine derivatives
ES9501534A ES2095811B1 (es) 1995-07-28 1995-07-28 Nuevos derivados de arilpiperazinas.
PCT/ES1995/000094 WO1996006846A1 (es) 1994-09-01 1995-07-28 Nuevos derivados de arilpiperazinas

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9501534A ES2095811B1 (es) 1995-07-28 1995-07-28 Nuevos derivados de arilpiperazinas.

Publications (2)

Publication Number Publication Date
ES2095811A1 true ES2095811A1 (es) 1997-02-16
ES2095811B1 ES2095811B1 (es) 1997-08-01

Family

ID=8291213

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9501534A Expired - Fee Related ES2095811B1 (es) 1994-09-01 1995-07-28 Nuevos derivados de arilpiperazinas.

Country Status (1)

Country Link
ES (1) ES2095811B1 (es)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2092785A1 (en) * 1970-06-18 1972-01-28 Hokuriku Pharmaceutical 2-azaquinolizidine derivs and salts neurotropic and anti - -histamine agents synthesis
US3717634A (en) * 1969-11-24 1973-02-20 Mead Johnson & Co N-(heteroarcyclic)piperazinylalkyl-azaspiroalkanediones
EP0256936A1 (fr) * 1986-08-12 1988-02-24 Rhone-Poulenc Sante Nouveaux dérivés de la benzyl-4 pipérazine, leur préparation et les compositions pharmaceutiques qui les contiennent
EP0296048A1 (fr) * 1987-06-15 1988-12-21 Adir Et Compagnie Nouveaux dérivés de la pipérazinyl alkyl piperazine dione, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent
EP0362555A1 (de) * 1988-09-03 1990-04-11 Hoechst Aktiengesellschaft Piperazindione mit psychotroper Wirkung

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3717634A (en) * 1969-11-24 1973-02-20 Mead Johnson & Co N-(heteroarcyclic)piperazinylalkyl-azaspiroalkanediones
FR2092785A1 (en) * 1970-06-18 1972-01-28 Hokuriku Pharmaceutical 2-azaquinolizidine derivs and salts neurotropic and anti - -histamine agents synthesis
EP0256936A1 (fr) * 1986-08-12 1988-02-24 Rhone-Poulenc Sante Nouveaux dérivés de la benzyl-4 pipérazine, leur préparation et les compositions pharmaceutiques qui les contiennent
EP0296048A1 (fr) * 1987-06-15 1988-12-21 Adir Et Compagnie Nouveaux dérivés de la pipérazinyl alkyl piperazine dione, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent
EP0362555A1 (de) * 1988-09-03 1990-04-11 Hoechst Aktiengesellschaft Piperazindione mit psychotroper Wirkung

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PERRONE R. y col. Mixed 5HT1A/D-2, Activity of a New Model of Arylpiperazines: 1-Aryl-4-(3-(1,2-dihydronaphthalen-4-yl)-n-propil) piperazines. 1. Synthesis and Structure - Activity Relationships. Journal of Medicinal Chemistry, 1994, Vol. 37, N‘ 1, pßginas 99-104 * Todo el documento * *

Also Published As

Publication number Publication date
ES2095811B1 (es) 1997-08-01

Similar Documents

Publication Publication Date Title
MXPA04004982A (es) Derivados de benzotiazol.
ATE195938T1 (de) 2-(1',2',4'-triazol-3'yloxymethylen)-anilide und ihre verwendung als schädlingsbekämpfungsmittel
NO931151D0 (no) Fremgangsmaate for fremstilling av nitrogenholdige heterocykliske forbindelser med kondenserte ringer
HUP0203645A2 (hu) Fenilpiperazinil-származékok, ezeket tartalmazó gyógyszerkészítmények és alkalmazásuk
SG19995G (en) Novel 3-arylindole and 3-arylindazole derivatives
ATE378046T1 (de) Carbamatverbindungen zur vorbeugung oder behandlung bipolarer erkrankungen
DE69412016T2 (de) Substituierte arylalkoxybenzyl-aminopropanamide, ihre herstellung und verwendung als antiepileptische, neuroprotektive und antidepressive mittel
HUP0001093A2 (hu) 5-HT2A-antagonista oxazolidinon-származékok, az ezeket tartalmazó gyógyszerkészítmények és eljárás előállításukra
ES514619A0 (es) "procedimiento para la preparacion de derivados de arilamina".
EA200200523A1 (ru) Новые разветвленные замещенные аминопроизводные 3-амино-1-фенил-1h[1,2,4]триазола, способы их получения и содержащие их фармацевтические композиции
ES2095811A1 (es) Nuevos derivados de arilpiperazinas.
ES8802051A1 (es) Un metodo para preparar derivados de 9-bencilpurina
ATE150751T1 (de) Neuroprotektive 3,4-dihydro-2(1h)-chinolone
ATE191465T1 (de) Carbamoylcarbonsäureamide
EA200400469A1 (ru) Замещенные производные алкиламинопиридазинона, способ их получения и содержащие их фармацевтические композиции
ES2082727A1 (es) Nuevos derivados de arilpiperazinas.
ES2094690A1 (es) Nuevos derivados de imida-piperazinas.
DE69732359D1 (de) Disubstituierte morpholin-, oxazepin- oder thiazepinderivate, deren herstellung und verwendung als dopamin-d4-rezeptorantagonisten
ATE108444T1 (de) 3-isoxazolonderivate, ihre herstellung und ihre anwendung in der therapeutik.
ATE227718T1 (de) N-aryloxyethyl-indolyl-alkylamine zur behandlung von depressionen
NO308304B1 (no) Nye 5H-thiazol[3,2-a]pyrimidin-5-on derivater, anvendelse derav for fremstilling av farmasøytiske sammensetninger, farmasøytiske sammensetninger inneholdende derivatene, samt et preparat til behandling av psykose, schizofreni og angst

Legal Events

Date Code Title Description
EC2A Search report published

Date of ref document: 19970216

Kind code of ref document: A1

Effective date: 19970216

FD2A Announcement of lapse in spain

Effective date: 20151104