ES2082727A1 - Nuevos derivados de arilpiperazinas. - Google Patents

Nuevos derivados de arilpiperazinas.

Info

Publication number
ES2082727A1
ES2082727A1 ES09401895A ES9401895A ES2082727A1 ES 2082727 A1 ES2082727 A1 ES 2082727A1 ES 09401895 A ES09401895 A ES 09401895A ES 9401895 A ES9401895 A ES 9401895A ES 2082727 A1 ES2082727 A1 ES 2082727A1
Authority
ES
Spain
Prior art keywords
alkyl
new
arylpiperazine derivatives
compounds
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES09401895A
Other languages
English (en)
Other versions
ES2082727B1 (es
Inventor
Rodriguez Maria Luz Lopez
Samitier Maria Luisa Rosado
Salama Bellinda Benhamu
Velando Esther Fernandez
Ortega Maria Jose Morcillo
Munoz Luis Miguel Orensanz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universidad Complutense de Madrid
Original Assignee
Universidad Complutense de Madrid
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universidad Complutense de Madrid filed Critical Universidad Complutense de Madrid
Priority to ES9401895A priority Critical patent/ES2082727B1/es
Priority to AU30792/95A priority patent/AU3079295A/en
Priority to PCT/ES1995/000094 priority patent/WO1996006846A1/es
Publication of ES2082727A1 publication Critical patent/ES2082727A1/es
Application granted granted Critical
Publication of ES2082727B1 publication Critical patent/ES2082727B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

NUEVOS DERIVADOS DE ARILPIPERAZINAS. LA PRESENTE INVENCION TRATA DE NUEVOS COMPUESTOS DE FORMULA GENERAL I, DONDE X ES (CH2)3- O -(CH2)4-; M ES IGUAL A CERO O 1; N ES IGUAL A 1, 2, 3 O 4. AR ES NAFTILO, BENZOFURANO, BENZODIOXANO, FENILO O FENILO SUSTITUIDO POR ALQUILO, HALOGENO, TRIFLUORMETILO, NITRO, CIANO, ALCOXI, AMINO, ALQUILCARBAMOILO, ALQUILSULFONAMIDO O ALCOXICARBONILO. SE DESCRIBEN LOS DIFERENTES METODOS ALTERNATIVOS DE PREPARACION DE DICHOS COMPUESTOS, LOS CUALES PRESENTAN AFINIDAD POR EL RECEPTOR SEROTONINERGICO 5-HT1A, LO QUE INDICA SU UTILIDAD DESDE EL PUNTO DE VISTA TERAPEUTICO EN EL TRATAMIENTO DE TRASTORNOS EN EL SNC, TALES COMO LA ANSIEDAD Y DEPRESION.
ES9401895A 1994-09-01 1994-09-01 Nuevos derivados de arilpiperazinas. Expired - Fee Related ES2082727B1 (es)

Priority Applications (3)

Application Number Priority Date Filing Date Title
ES9401895A ES2082727B1 (es) 1994-09-01 1994-09-01 Nuevos derivados de arilpiperazinas.
AU30792/95A AU3079295A (en) 1994-09-01 1995-07-28 New arylpiperazine derivatives
PCT/ES1995/000094 WO1996006846A1 (es) 1994-09-01 1995-07-28 Nuevos derivados de arilpiperazinas

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9401895A ES2082727B1 (es) 1994-09-01 1994-09-01 Nuevos derivados de arilpiperazinas.

Publications (2)

Publication Number Publication Date
ES2082727A1 true ES2082727A1 (es) 1996-03-16
ES2082727B1 ES2082727B1 (es) 1996-10-16

Family

ID=8287378

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9401895A Expired - Fee Related ES2082727B1 (es) 1994-09-01 1994-09-01 Nuevos derivados de arilpiperazinas.

Country Status (1)

Country Link
ES (1) ES2082727B1 (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7351732B2 (en) 2002-07-31 2008-04-01 Schwarz Pharma S.L. Cycloalkanedione derivatives, method for the production thereof and their pharmacological applications

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2092785A1 (en) * 1970-06-18 1972-01-28 Hokuriku Pharmaceutical 2-azaquinolizidine derivs and salts neurotropic and anti - -histamine agents synthesis
US3717634A (en) * 1969-11-24 1973-02-20 Mead Johnson & Co N-(heteroarcyclic)piperazinylalkyl-azaspiroalkanediones
EP0256936A1 (fr) * 1986-08-12 1988-02-24 Rhone-Poulenc Sante Nouveaux dérivés de la benzyl-4 pipérazine, leur préparation et les compositions pharmaceutiques qui les contiennent
EP0296048A1 (fr) * 1987-06-15 1988-12-21 Adir Et Compagnie Nouveaux dérivés de la pipérazinyl alkyl piperazine dione, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent
EP0362555A1 (de) * 1988-09-03 1990-04-11 Hoechst Aktiengesellschaft Piperazindione mit psychotroper Wirkung

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3717634A (en) * 1969-11-24 1973-02-20 Mead Johnson & Co N-(heteroarcyclic)piperazinylalkyl-azaspiroalkanediones
FR2092785A1 (en) * 1970-06-18 1972-01-28 Hokuriku Pharmaceutical 2-azaquinolizidine derivs and salts neurotropic and anti - -histamine agents synthesis
EP0256936A1 (fr) * 1986-08-12 1988-02-24 Rhone-Poulenc Sante Nouveaux dérivés de la benzyl-4 pipérazine, leur préparation et les compositions pharmaceutiques qui les contiennent
EP0296048A1 (fr) * 1987-06-15 1988-12-21 Adir Et Compagnie Nouveaux dérivés de la pipérazinyl alkyl piperazine dione, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent
EP0362555A1 (de) * 1988-09-03 1990-04-11 Hoechst Aktiengesellschaft Piperazindione mit psychotroper Wirkung

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PERRONE, R. y col. Mixed 5-HT1A/D-2, Activity of a New Model of Arylpiperazines: 1-Aryl-4-(3-(1,2-dihydronaphthalen-4-yl)-n- propyl) piperazines. 1. Synthesis and Structure - Activity Relationships. Journal of Medicinal Chemistry, 1994, Vol. 37, N‘ 1, pßginas 99-104 * Todo el documento * *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7351732B2 (en) 2002-07-31 2008-04-01 Schwarz Pharma S.L. Cycloalkanedione derivatives, method for the production thereof and their pharmacological applications

Also Published As

Publication number Publication date
ES2082727B1 (es) 1996-10-16

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