ES2082727A1 - Nuevos derivados de arilpiperazinas. - Google Patents
Nuevos derivados de arilpiperazinas.Info
- Publication number
- ES2082727A1 ES2082727A1 ES09401895A ES9401895A ES2082727A1 ES 2082727 A1 ES2082727 A1 ES 2082727A1 ES 09401895 A ES09401895 A ES 09401895A ES 9401895 A ES9401895 A ES 9401895A ES 2082727 A1 ES2082727 A1 ES 2082727A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- new
- arylpiperazine derivatives
- compounds
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
NUEVOS DERIVADOS DE ARILPIPERAZINAS. LA PRESENTE INVENCION TRATA DE NUEVOS COMPUESTOS DE FORMULA GENERAL I, DONDE X ES (CH2)3- O -(CH2)4-; M ES IGUAL A CERO O 1; N ES IGUAL A 1, 2, 3 O 4. AR ES NAFTILO, BENZOFURANO, BENZODIOXANO, FENILO O FENILO SUSTITUIDO POR ALQUILO, HALOGENO, TRIFLUORMETILO, NITRO, CIANO, ALCOXI, AMINO, ALQUILCARBAMOILO, ALQUILSULFONAMIDO O ALCOXICARBONILO. SE DESCRIBEN LOS DIFERENTES METODOS ALTERNATIVOS DE PREPARACION DE DICHOS COMPUESTOS, LOS CUALES PRESENTAN AFINIDAD POR EL RECEPTOR SEROTONINERGICO 5-HT1A, LO QUE INDICA SU UTILIDAD DESDE EL PUNTO DE VISTA TERAPEUTICO EN EL TRATAMIENTO DE TRASTORNOS EN EL SNC, TALES COMO LA ANSIEDAD Y DEPRESION.
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9401895A ES2082727B1 (es) | 1994-09-01 | 1994-09-01 | Nuevos derivados de arilpiperazinas. |
AU30792/95A AU3079295A (en) | 1994-09-01 | 1995-07-28 | New arylpiperazine derivatives |
PCT/ES1995/000094 WO1996006846A1 (es) | 1994-09-01 | 1995-07-28 | Nuevos derivados de arilpiperazinas |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9401895A ES2082727B1 (es) | 1994-09-01 | 1994-09-01 | Nuevos derivados de arilpiperazinas. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2082727A1 true ES2082727A1 (es) | 1996-03-16 |
ES2082727B1 ES2082727B1 (es) | 1996-10-16 |
Family
ID=8287378
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES9401895A Expired - Fee Related ES2082727B1 (es) | 1994-09-01 | 1994-09-01 | Nuevos derivados de arilpiperazinas. |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES2082727B1 (es) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7351732B2 (en) | 2002-07-31 | 2008-04-01 | Schwarz Pharma S.L. | Cycloalkanedione derivatives, method for the production thereof and their pharmacological applications |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2092785A1 (en) * | 1970-06-18 | 1972-01-28 | Hokuriku Pharmaceutical | 2-azaquinolizidine derivs and salts neurotropic and anti - -histamine agents synthesis |
US3717634A (en) * | 1969-11-24 | 1973-02-20 | Mead Johnson & Co | N-(heteroarcyclic)piperazinylalkyl-azaspiroalkanediones |
EP0256936A1 (fr) * | 1986-08-12 | 1988-02-24 | Rhone-Poulenc Sante | Nouveaux dérivés de la benzyl-4 pipérazine, leur préparation et les compositions pharmaceutiques qui les contiennent |
EP0296048A1 (fr) * | 1987-06-15 | 1988-12-21 | Adir Et Compagnie | Nouveaux dérivés de la pipérazinyl alkyl piperazine dione, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent |
EP0362555A1 (de) * | 1988-09-03 | 1990-04-11 | Hoechst Aktiengesellschaft | Piperazindione mit psychotroper Wirkung |
-
1994
- 1994-09-01 ES ES9401895A patent/ES2082727B1/es not_active Expired - Fee Related
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3717634A (en) * | 1969-11-24 | 1973-02-20 | Mead Johnson & Co | N-(heteroarcyclic)piperazinylalkyl-azaspiroalkanediones |
FR2092785A1 (en) * | 1970-06-18 | 1972-01-28 | Hokuriku Pharmaceutical | 2-azaquinolizidine derivs and salts neurotropic and anti - -histamine agents synthesis |
EP0256936A1 (fr) * | 1986-08-12 | 1988-02-24 | Rhone-Poulenc Sante | Nouveaux dérivés de la benzyl-4 pipérazine, leur préparation et les compositions pharmaceutiques qui les contiennent |
EP0296048A1 (fr) * | 1987-06-15 | 1988-12-21 | Adir Et Compagnie | Nouveaux dérivés de la pipérazinyl alkyl piperazine dione, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent |
EP0362555A1 (de) * | 1988-09-03 | 1990-04-11 | Hoechst Aktiengesellschaft | Piperazindione mit psychotroper Wirkung |
Non-Patent Citations (1)
Title |
---|
PERRONE, R. y col. Mixed 5-HT1A/D-2, Activity of a New Model of Arylpiperazines: 1-Aryl-4-(3-(1,2-dihydronaphthalen-4-yl)-n- propyl) piperazines. 1. Synthesis and Structure - Activity Relationships. Journal of Medicinal Chemistry, 1994, Vol. 37, N‘ 1, pßginas 99-104 * Todo el documento * * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7351732B2 (en) | 2002-07-31 | 2008-04-01 | Schwarz Pharma S.L. | Cycloalkanedione derivatives, method for the production thereof and their pharmacological applications |
Also Published As
Publication number | Publication date |
---|---|
ES2082727B1 (es) | 1996-10-16 |
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