ATE227718T1 - N-aryloxyethyl-indolyl-alkylamine zur behandlung von depressionen - Google Patents

N-aryloxyethyl-indolyl-alkylamine zur behandlung von depressionen

Info

Publication number
ATE227718T1
ATE227718T1 AT99916480T AT99916480T ATE227718T1 AT E227718 T1 ATE227718 T1 AT E227718T1 AT 99916480 T AT99916480 T AT 99916480T AT 99916480 T AT99916480 T AT 99916480T AT E227718 T1 ATE227718 T1 AT E227718T1
Authority
AT
Austria
Prior art keywords
hydrogen
aryloxyethyl
alkylamines
indolyl
depression
Prior art date
Application number
AT99916480T
Other languages
English (en)
Inventor
Richard Eric Mewshaw
James Albert Nelson
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Application granted granted Critical
Publication of ATE227718T1 publication Critical patent/ATE227718T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/34—One oxygen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Psychiatry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Control Of El Displays (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT99916480T 1998-04-08 1999-04-07 N-aryloxyethyl-indolyl-alkylamine zur behandlung von depressionen ATE227718T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5715998A 1998-04-08 1998-04-08
PCT/US1999/007658 WO1999051591A2 (en) 1998-04-08 1999-04-07 N-aryloxyethyl-indoly-alkylamines for the treatment of depression

Publications (1)

Publication Number Publication Date
ATE227718T1 true ATE227718T1 (de) 2002-11-15

Family

ID=22008868

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99916480T ATE227718T1 (de) 1998-04-08 1999-04-07 N-aryloxyethyl-indolyl-alkylamine zur behandlung von depressionen

Country Status (11)

Country Link
EP (1) EP1068199B1 (de)
JP (1) JP2002510681A (de)
CN (1) CN1135228C (de)
AT (1) ATE227718T1 (de)
AU (1) AU3479299A (de)
CA (1) CA2327513A1 (de)
DE (1) DE69903930T2 (de)
DK (1) DK1068199T3 (de)
ES (1) ES2188155T3 (de)
PT (1) PT1068199E (de)
WO (1) WO1999051591A2 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108993496B (zh) * 2018-10-30 2021-01-15 山东第一医科大学(山东省医学科学院) 一种治疗运动障碍用药物罗匹尼罗中间体的制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3371098A (en) * 1966-11-29 1968-02-27 Philips Corp 5- and 6-methoxy-3-(phenoxyethyl-aminoethyl)-indoles
GB8719167D0 (en) * 1987-08-13 1987-09-23 Glaxo Group Ltd Chemical compounds
US4954502A (en) * 1988-06-10 1990-09-04 Bristol-Myers Squibb Company 1-indolyalkyl-4-(substituted-pyridinyl)piperazines
DK37790A (da) * 1990-02-13 1991-08-14 Novo Nordisk As Indolderivater, deres fremstilling og anvendelse
US5189179A (en) * 1990-08-29 1993-02-23 Merrell Dow Pharmaceuticals Inc. Serotonin 5ht1a agonists
JPH05255302A (ja) * 1992-03-09 1993-10-05 Yamanouchi Pharmaceut Co Ltd 新規なクロマニルオキシアルキルアミン誘導体
US5521197A (en) * 1994-12-01 1996-05-28 Eli Lilly And Company 3-<1-alkylenearyl>-4-<1,2,3,6-tetrahydropyridinyl>-and 3-<1-alkylenearyl>-4-piperidinyl-1h-indoles: new 5-HT1F agonists
JPH0940648A (ja) * 1995-08-02 1997-02-10 Yamanouchi Pharmaceut Co Ltd 新規な８−（２−アミノアルコキシ）キノリン誘導体
DE19615232A1 (de) * 1996-04-18 1997-10-23 Merck Patent Gmbh Neue Carbamoylderivate und deren Verwendung als 5-HT ¶1¶¶A¶-Antagonisten
US5846982A (en) * 1996-06-14 1998-12-08 Eli Lilly And Company Inhibition of serotonin reuptake
EP0923551B1 (de) * 1996-08-27 2002-06-05 American Home Products Corporation 4-aminoethoxy-indolon-derivate
DK0923548T3 (da) * 1996-08-27 2003-06-23 Wyeth Corp 4-Aminoethoxyindoler som dopamin-D2-agonister og som 5HT 1A-ligander
ZA9711376B (en) * 1996-12-20 1998-07-21 Lundbeck & Co As H Indole or dihydroindole derivatives

Also Published As

Publication number Publication date
JP2002510681A (ja) 2002-04-09
AU3479299A (en) 1999-10-25
PT1068199E (pt) 2003-02-28
DE69903930D1 (de) 2002-12-19
DK1068199T3 (da) 2003-03-03
EP1068199A2 (de) 2001-01-17
EP1068199B1 (de) 2002-11-13
CN1304407A (zh) 2001-07-18
ES2188155T3 (es) 2003-06-16
WO1999051591A2 (en) 1999-10-14
WO1999051591A3 (en) 1999-12-09
CN1135228C (zh) 2004-01-21
CA2327513A1 (en) 1999-10-14
DE69903930T2 (de) 2003-07-17

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