ES2092474T3 - Proteinas con propiedades anabolicas de la hormona del crecimiento con efecto reducido sobre el metabolismo de los hidratos de carbono. - Google Patents

Proteinas con propiedades anabolicas de la hormona del crecimiento con efecto reducido sobre el metabolismo de los hidratos de carbono.

Info

Publication number
ES2092474T3
ES2092474T3 ES89308257T ES89308257T ES2092474T3 ES 2092474 T3 ES2092474 T3 ES 2092474T3 ES 89308257 T ES89308257 T ES 89308257T ES 89308257 T ES89308257 T ES 89308257T ES 2092474 T3 ES2092474 T3 ES 2092474T3
Authority
ES
Spain
Prior art keywords
growth hormone
metabolism
proteins
reduced effect
carbon hydrates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89308257T
Other languages
English (en)
Inventor
Gerald Wayne Becker
Carl Joseph Shaar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of ES2092474T3 publication Critical patent/ES2092474T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

ESTA ESPECIFICACION DESCRIBE UNA HORMONA DE CRECIMIENTO MODIFICADA, QUE TIENE DISMINUIDAS LA EFICACIA SIMILAR A LA INSULINA Y DIABETOGENICA EN RALACION CON LA HORMONA NATURAL, CON RETENCION DE PRACTICAMENTE TODA LA EFICACIA ANABOLICA DE LA HORMONA NATURAL.
ES89308257T 1988-08-19 1989-08-15 Proteinas con propiedades anabolicas de la hormona del crecimiento con efecto reducido sobre el metabolismo de los hidratos de carbono. Expired - Lifetime ES2092474T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/233,772 US5079345A (en) 1988-08-19 1988-08-19 Proteins having growth hormone anabolic properties with reduced effect on carbohydrate metabolism

Publications (1)

Publication Number Publication Date
ES2092474T3 true ES2092474T3 (es) 1996-12-01

Family

ID=22878632

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89308257T Expired - Lifetime ES2092474T3 (es) 1988-08-19 1989-08-15 Proteinas con propiedades anabolicas de la hormona del crecimiento con efecto reducido sobre el metabolismo de los hidratos de carbono.

Country Status (6)

Country Link
US (1) US5079345A (es)
EP (1) EP0356107B1 (es)
JP (1) JPH02108698A (es)
CA (1) CA1339046C (es)
DE (1) DE68927316T2 (es)
ES (1) ES2092474T3 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6583115B1 (en) 1989-10-12 2003-06-24 Ohio University/Edison Biotechnology Institute Methods for treating acromegaly and giantism with growth hormone antagonists
US5958879A (en) * 1989-10-12 1999-09-28 Ohio University/Edison Biotechnology Institute Growth hormone receptor antagonists and methods of reducing growth hormone activity in a mammal
US5350836A (en) * 1989-10-12 1994-09-27 Ohio University Growth hormone antagonists
US6787336B1 (en) 1989-10-12 2004-09-07 Ohio University/Edison Biotechnology Institute DNA encoding growth hormone antagonists
US6946265B1 (en) 1999-05-12 2005-09-20 Xencor, Inc. Nucleic acids and proteins with growth hormone activity
SE0000837D0 (sv) * 2000-03-13 2000-03-13 Pharmacia & Upjohn Ab New use
ES2343518T3 (es) * 2002-09-09 2010-08-03 Hanall Biopharma Co., Ltd. Polipeptidos interferon alfa modificados resistentes a proteasas.
WO2006012525A2 (en) * 2004-07-23 2006-02-02 Neuren Pharmaceuticals Limited Non-diabetogenic therapy using a 20kda placental growth hormone variant
US7998930B2 (en) 2004-11-04 2011-08-16 Hanall Biopharma Co., Ltd. Modified growth hormones
WO2011103325A1 (en) 2010-02-17 2011-08-25 Elona Biotechnologies Methods for preparing human growth hormone

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1066215B (it) * 1975-09-08 1985-03-04 Scripps Clinic Res Procedimento per la produzione di prodotti di trasformazione dell or mone umano di crescita
US4446235A (en) * 1982-03-22 1984-05-01 Genentech, Inc. Method for cloning human growth hormone varient genes
BG49718A3 (en) * 1983-07-15 1992-01-15 Bio Technology General Corp Method for preparing of polypeptid with superoxiddismutasne activitty
DE3588249T2 (de) * 1984-08-16 2004-05-06 Savient Pharmaceuticals, Inc. Methode zur Herstellung von menschlichen Wachstumshormonen

Also Published As

Publication number Publication date
US5079345A (en) 1992-01-07
EP0356107B1 (en) 1996-10-09
JPH02108698A (ja) 1990-04-20
EP0356107A3 (en) 1991-08-14
EP0356107A2 (en) 1990-02-28
DE68927316T2 (de) 1997-03-06
DE68927316D1 (de) 1996-11-14
CA1339046C (en) 1997-04-01

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