ES2092122T3 - Dispositivo suministrador de larga duracion que incluye una dosis de carga hidrofuga. - Google Patents

Dispositivo suministrador de larga duracion que incluye una dosis de carga hidrofuga.

Info

Publication number
ES2092122T3
ES2092122T3 ES92913865T ES92913865T ES2092122T3 ES 2092122 T3 ES2092122 T3 ES 2092122T3 ES 92913865 T ES92913865 T ES 92913865T ES 92913865 T ES92913865 T ES 92913865T ES 2092122 T3 ES2092122 T3 ES 2092122T3
Authority
ES
Spain
Prior art keywords
agent
long
delivery
dose
supply device
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92913865T
Other languages
English (en)
Inventor
John Patrick Carr
James B Eckenhoff
Terry L Burkoth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of ES2092122T3 publication Critical patent/ES2092122T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas

Abstract

LA INVENCION SUMINISTRA UN DISPOSITIVO DE DISPENSACION (20) QUE COMPRENDE UNA DOSIS DE CARGA (UN PRIMER MEDIO PARA LA LIBERACION DE UN AGENTE) (32) PARA LA LIBERACION CONTINUA Y A CORTO PLAZO DE UN AGENTE QUE TIENE UNA ALTA POTENCIA, RETENIDO JUNTO CON UN DISPOSITIVO DE DISPENSACION DE LARGO PLAZO (SEGUNDO MEDIO DE SUMINISTRO DE AGENTES) (12) CAPAZ DEL SUMINISTRO CONTINUO Y A LARGO PLAZO DE UN AGENTE. LA COMBINACION DE LOS PRIMEROS Y SEGUNDOS MEDIOS DE SUMINISTRO DEL AGENTE SUMINISTRA UN DISPOSITIVO EN EL QUE UNA DOSIS SUBSTANCIALMENTE CONSTANTE DE UN AGENTE BENEFICO PUEDE SUMINISTRARSE AL MEDIO DE USO A LO LARGO DEL TIEMPO. EL SUMINISTRO RAPIDO, INICIAL DEL AGENTE BENEFICIOSO ES SEGUIDO POR UN SUMINISTRO CONTINUO Y PROLONGADO DEL AGENTE. EN UNA CONFORMACION MAS ADECUADA, EL DISPOSITIVO INCLUYE 1) UNA CAMARA PARA LA DOSIS DE CARGA (30) Y MEDIOS DE RETENCION (16) PARA RETENER UNA DOSIS DE CARGA (32) PARA EL SUMINISTRO RAPIDO Y CONTINUO DEL AGENTE QUE TIENE UNA ALTA POTENCIA CON RESPECTO AL MEDIO DE USO; Y 2) UN DISPOSITIVO DE DISPENSACION A LARGO PLAZO (12) QUE COMPRENDE UNA PARED SEMIPERMEABLE (14) QUE RODEA Y DEFINE UN LUMEN INTERNO (20), UNA FUENTE IMPULSORA (MEDIOS DE EXPANSION) (22) EN EL LUMEN PARA EXPANDIR Y OCUPAR UN VOLUMEN INCREMENTADO DEL LUMEN, UN AGENTE BENEFICIOSO (24) EN EL LUMEN QUE SUMINISTRA UNA FORMULACION DISPENSABLE AL MEDIO DE USO Y UNA SALIDA (28) EN EL DISPOSITIVO PARA SUMINISTRAR EL AGENTE BENEFICO AL MEDIO DE USO A LO LARGO DE UN PERIODO DE TIEMPO. TAMBIEN PUEDE INCLUIRSE UN DENSIFICADOR (24) Y/O UN MEDIO DE BARRERA MOVIL (34) EN EL LUMEN DEL DISPOSITIVO DE DISPENSACION A LARGO PLAZO.
ES92913865T 1991-06-11 1992-06-11 Dispositivo suministrador de larga duracion que incluye una dosis de carga hidrofuga. Expired - Lifetime ES2092122T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71454491A 1991-06-11 1991-06-11
US07/842,939 US5227167A (en) 1991-06-11 1992-02-27 Long-term delivery device including hydrophobic loading dose

Publications (1)

Publication Number Publication Date
ES2092122T3 true ES2092122T3 (es) 1996-11-16

Family

ID=27109175

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92913865T Expired - Lifetime ES2092122T3 (es) 1991-06-11 1992-06-11 Dispositivo suministrador de larga duracion que incluye una dosis de carga hidrofuga.

Country Status (14)

Country Link
US (1) US5227167A (es)
EP (1) EP0588947B1 (es)
JP (1) JP3399527B2 (es)
KR (1) KR0137261B1 (es)
AT (1) ATE141525T1 (es)
AU (1) AU653425B2 (es)
CA (1) CA2109698C (es)
DE (1) DE69213009T2 (es)
ES (1) ES2092122T3 (es)
IE (1) IE69377B1 (es)
MX (1) MX9202800A (es)
NZ (1) NZ243105A (es)
PT (1) PT100586B (es)
WO (1) WO1992022346A1 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5308348A (en) * 1992-02-18 1994-05-03 Alza Corporation Delivery devices with pulsatile effect
US5456679A (en) * 1992-02-18 1995-10-10 Alza Corporation Delivery devices with pulsatile effect
US5540926A (en) * 1992-09-04 1996-07-30 Bristol-Myers Squibb Company Soluble and its use in B cell stimulation
US5672357A (en) * 1994-07-01 1997-09-30 Monsanto Company Method and device for implantation of large diameter objects in bovines
US5595752A (en) * 1994-07-01 1997-01-21 Monsanto Company Increasing dressing percentage and carcass weight in finishing beef cattle
US5906833A (en) * 1995-05-22 1999-05-25 Klatz; Ronald M. Chronological food bar
US20020131988A1 (en) * 1999-12-16 2002-09-19 Foster Todd P. Pharmaceutical implant containing immediate-release and sustained-release components and method of administration
DE102004042578A1 (de) * 2004-09-02 2006-03-23 Roche Diagnostics Gmbh Mikropumpe zur Förderung von Flüssigkeiten mit niedrigen Förderraten im Druck/Saug-Betrieb
US20070190137A1 (en) * 2005-10-07 2007-08-16 Reyes Iran Osmotic dosage form with controlled release and fast release aspects
US20110251568A1 (en) * 2010-04-08 2011-10-13 Beeley Nathan R F Punctal plugs for controlled release of therapeutic agents
AU2021396978A1 (en) 2020-12-08 2023-02-23 Ruminant Biotech Corp Limited Improvements to devices and methods for delivery of substances to animals

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3845770A (en) * 1972-06-05 1974-11-05 Alza Corp Osmatic dispensing device for releasing beneficial agent
US3916899A (en) * 1973-04-25 1975-11-04 Alza Corp Osmotic dispensing device with maximum and minimum sizes for the passageway
US3995632A (en) * 1973-05-04 1976-12-07 Alza Corporation Osmotic dispenser
US4381780A (en) * 1981-01-19 1983-05-03 Research Corporation Sustained release delivery system
CH652025A5 (de) * 1981-09-14 1985-10-31 Hoffmann La Roche Pharmazeutisches praeparat.
US4564363A (en) * 1983-07-13 1986-01-14 Smithkline Beckman Corporation Delayed action assembly
GB8328916D0 (en) * 1983-10-28 1983-11-30 Castex Prod Pharmaceutical pellet
US4844984A (en) * 1984-03-19 1989-07-04 Alza Corporation Dispensing system with means for increasing delivery of beneficial agent from the system
US4729793A (en) * 1985-08-09 1988-03-08 Alza Corporation Composition for manufacturing wall of dispensing device
US4772474A (en) * 1985-08-09 1988-09-20 Alza Corporation Dispenser with internal arrangement of lamina means for dispensing beneficial agent
US4612186A (en) * 1984-03-19 1986-09-16 Alza Corporation Method for establishing blood levels of biocide in animals
US5000957A (en) * 1984-03-19 1991-03-19 Alza Corporation Dispenser comprising hydrophilic osmopolymer
US4595583A (en) * 1984-03-19 1986-06-17 Alza Corporation Delivery system controlled administration of beneficial agent to ruminants
GB8417202D0 (en) * 1984-07-05 1984-08-08 Norbrook Lab Ltd Drug intermittent release device
US4693886A (en) * 1985-04-22 1987-09-15 Alza Corporation Osmotic device with inert core
US4704118A (en) * 1985-08-16 1987-11-03 Alza Corporation Ruminant dispensing device with thermo-activated memory
US4643731A (en) * 1985-08-16 1987-02-17 Alza Corporation Means for providing instant agent from agent dispensing system
US5023088A (en) * 1987-06-25 1991-06-11 Alza Corporation Multi-unit delivery system
US4814181A (en) * 1987-09-03 1989-03-21 Alza Corporation Dosage form comprising fast agent delivery followed by slow agent delivery
US4872873A (en) * 1987-12-14 1989-10-10 Merck & Co., Inc. Controlled release bolus device
US5045082A (en) * 1990-01-10 1991-09-03 Alza Corporation Long-term delivery device including loading dose

Also Published As

Publication number Publication date
IE921885A1 (en) 1992-12-16
WO1992022346A1 (en) 1992-12-23
AU653425B2 (en) 1994-09-29
JPH06507912A (ja) 1994-09-08
PT100586B (pt) 1999-06-30
CA2109698A1 (en) 1992-12-23
NZ243105A (en) 1994-07-26
US5227167A (en) 1993-07-13
ATE141525T1 (de) 1996-09-15
JP3399527B2 (ja) 2003-04-21
EP0588947A1 (en) 1994-03-30
KR940701285A (ko) 1994-05-28
DE69213009D1 (de) 1996-09-26
AU2193392A (en) 1993-01-12
EP0588947B1 (en) 1996-08-21
IE69377B1 (en) 1996-09-04
PT100586A (pt) 1994-05-31
KR0137261B1 (ko) 1998-04-25
DE69213009T2 (de) 1996-12-19
CA2109698C (en) 1996-10-22
MX9202800A (es) 1992-12-01

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