ES2056636T3 - Dispositivo de suministro a largo plazo que incluye una dosis de carga. - Google Patents

Dispositivo de suministro a largo plazo que incluye una dosis de carga.

Info

Publication number
ES2056636T3
ES2056636T3 ES91902329T ES91902329T ES2056636T3 ES 2056636 T3 ES2056636 T3 ES 2056636T3 ES 91902329 T ES91902329 T ES 91902329T ES 91902329 T ES91902329 T ES 91902329T ES 2056636 T3 ES2056636 T3 ES 2056636T3
Authority
ES
Spain
Prior art keywords
agent
delivery
term
long
lumen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91902329T
Other languages
English (en)
Inventor
Atul Devdatt Ayer
James B Eckenhoff
Jeremy C Wright
Anthony L Kuczynski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of ES2056636T3 publication Critical patent/ES2056636T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0068—Rumen, e.g. rumen bolus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Medicinal Preparation (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
  • Filling Or Emptying Of Bunkers, Hoppers, And Tanks (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Testing Of Optical Devices Or Fibers (AREA)
  • Bidet-Like Cleaning Device And Other Flush Toilet Accessories (AREA)
  • Length Measuring Devices By Optical Means (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Glanulating (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Basic Packing Technique (AREA)
  • De-Stacking Of Articles (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

LA INVENCION PROPORCIONA UN DISPOSITIVO DISPENSADOR (10) QUE COMPRENDE UNA DOSIS DE CARGA (32) (PRIMER MEDIO DE DISTRIBUCION DEL AGENTE) PARA DISTRIBUCION A CORTO PLAZO Y CONTINUA DEL AGENTE, RETENIDO JUNTO CON UN DISPOSITIVO DISPENSADOR A LARGO PLAZO (12) (SEGUNDO MEDIO DE DISTRIBUCION DEL AGENTE) CAPAZ DE UNA DISTRIBUCION A LARGO PLAZO Y CONTINUA DEL AGENTE. LA COMBINACION DEL PRIMER Y SEGUNDO MEDIOS DE DISTRIBUCION DEL AGENTE PROPORCIONA UN DISPOSITIVO EN EL QUE SE DISTRIBUYE UNA DOSIS SUBSTANCIALMENTE CONSTANTE DEL AGENTE BENEFICO EN EL MEDIO DE UTILIZACION FUERA DEL TIEMPO NORMAL. UNA DISTRIBUCION RAPIDA DEL AGENTE BENEFICO VA SEGUIDA POR UNA DISTRIBUCION CONTINUA Y PROLONGADA DEL AGENTE. EN UNA REALIZACION PREFERIDA EL DISPOSITIVO INCLUYE (A) UNA CAMARA DE CARGA DE DOSIS (30) Y UN MEDIO DE RETENCION (16) QUE RETIENE UNA DOSIS DE CARGA (32) (MEDIO DE DISTRIBUCION A CORTO PLAZO) PARA LA DISTRIBUCION RAPIDA Y CONTINUA DEL AGENTE EN EL MEDIO DE UTILIZACION; Y (B) UN DISPOSITIVO DE DISPENSACION A LARGO PLAZO (12) (MEDIO DE DISTRIBUCION A LARGO PLAZO) QUE COMPRENDE UNA PARED SEMIPERMEABLE (14) QUE RODEA Y DEFINE UNA ABERTURA INTERIOR (20), UNA FUENTE DE ACCIONAMIENTO (22) (MEDIO DE EXPANSION) EN LA ABERTURA INTERIOR PARA EXPANDIR Y OCUPAR UN VOLUMEN INCREMENTADO DE LA ABERTURA INTERIOR, UN AGENTE BENEFICO (24) EN LA ABERTURA INTERIOR QUE PROPORCIONA UNA FORMULACION DISPENSABLE EN EL MEDIO DE UTILIZACION, Y UNA SALIDA (28) EN EL DISPOSITIVO PARA LA DISTRIBUCION DEL AGENTE BENEFICO EN EL MEDIO DE UTILIZACION FUERA DEL TIEMPO NORMAL. TAMBIEN SE PUEDEN INCLUIR UN DENSIFICADOR (26) Y/O UN MEDIO BARRERA MOVIL (34) EN LA ABERTURA INTERIOR DEL DISPOSITIVO DISPENSADOR A LARGO PLAZO.
ES91902329T 1990-01-10 1990-12-21 Dispositivo de suministro a largo plazo que incluye una dosis de carga. Expired - Lifetime ES2056636T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/463,109 US5045082A (en) 1990-01-10 1990-01-10 Long-term delivery device including loading dose

Publications (1)

Publication Number Publication Date
ES2056636T3 true ES2056636T3 (es) 1994-10-01

Family

ID=23838902

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91902329T Expired - Lifetime ES2056636T3 (es) 1990-01-10 1990-12-21 Dispositivo de suministro a largo plazo que incluye una dosis de carga.

Country Status (18)

Country Link
US (2) US5045082A (es)
EP (1) EP0510062B1 (es)
JP (1) JP3301612B2 (es)
KR (1) KR0158704B1 (es)
AT (1) ATE108998T1 (es)
AU (1) AU642704B2 (es)
CA (1) CA2032923C (es)
DE (1) DE69011131T2 (es)
DK (1) DK0510062T3 (es)
ES (1) ES2056636T3 (es)
FI (1) FI105011B (es)
IE (1) IE62391B1 (es)
MX (1) MX169706B (es)
NO (1) NO303862B1 (es)
NZ (1) NZ236627A (es)
PT (1) PT96337B (es)
WO (1) WO1991010423A1 (es)
ZA (1) ZA9010342B (es)

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US5728088A (en) * 1988-12-13 1998-03-17 Alza Corporation Osmotic system for delivery of fluid-sensitive somatotropins to bovine animals
US5135523A (en) * 1988-12-13 1992-08-04 Alza Corporation Delivery system for administering agent to ruminants and swine
US5045082A (en) * 1990-01-10 1991-09-03 Alza Corporation Long-term delivery device including loading dose
US5229133A (en) * 1990-01-24 1993-07-20 Alza Corporation Delivery system comprising means for controlling internal pressure
US5474785A (en) * 1990-01-24 1995-12-12 Alza Corporation Delivery system comprising means for controlling internal pressure
US5223266A (en) * 1990-01-24 1993-06-29 Alza Corporation Long-term delivery device with early startup
US5213809A (en) * 1990-01-24 1993-05-25 Alza Corporation Delivery system comprising means for controlling internal pressure
DK0597834T3 (da) * 1990-01-24 1996-02-26 Alza Corp Afgivelsessystem
US5861166A (en) * 1991-03-12 1999-01-19 Alza Corporation Delivery device providing beneficial agent stability
US5201728A (en) * 1991-05-03 1993-04-13 Giampapa Vincent C Subcutaneous implantable multiple-agent delivery system
US5227167A (en) * 1991-06-11 1993-07-13 Alza Corporation Long-term delivery device including hydrophobic loading dose
US5240713A (en) * 1991-09-27 1993-08-31 Alza Corporation Dual rate agent delivery device
US5288214A (en) * 1991-09-30 1994-02-22 Toshio Fukuda Micropump
US5462741A (en) * 1992-08-06 1995-10-31 Alza Corporation High agent loaded controlled release dispenser
US5431919A (en) * 1993-06-23 1995-07-11 Alza Ruminal drug delivery device
US5639477A (en) * 1993-06-23 1997-06-17 Alza Corporation Ruminal drug delivery device
GB9318641D0 (en) * 1993-09-08 1993-10-27 Edko Trading Representation Compositions
NZ250188A (en) * 1993-11-11 1996-06-25 Ashmont Holdings Ltd Substitut Anthelmintic drench comprising an avermectin or milbemycin and an organic selenium salt
ZA948426B (en) * 1993-12-22 1995-06-30 Qualcomm Inc Distributed voice recognition system
US5672357A (en) * 1994-07-01 1997-09-30 Monsanto Company Method and device for implantation of large diameter objects in bovines
US5595752A (en) * 1994-07-01 1997-01-21 Monsanto Company Increasing dressing percentage and carcass weight in finishing beef cattle
US5433711A (en) * 1994-08-01 1995-07-18 Monsanto Company Syringe with cannula-protecting sheath and sealing center rod
US5690952A (en) * 1995-06-07 1997-11-25 Judy A. Magruder et al. Implantable system for delivery of fluid-sensitive agents to animals
FR2754711B1 (fr) * 1996-10-21 1999-01-29 Vandamme Thierry Dispositif de liberation avec effet retard d'une substance active, notamment veterinaire
GB2345010B (en) 1998-12-17 2002-12-31 Electrosols Ltd A delivery device
US6669954B2 (en) 2000-01-25 2003-12-30 John R. Crison Controlled release of drugs
GB0115355D0 (en) * 2001-06-22 2001-08-15 Pirrie Alastair Vaporization system
US20060020253A1 (en) * 2004-07-26 2006-01-26 Prescott Anthony D Implantable device having reservoir with controlled release of medication and method of manufacturing the same
WO2007044234A1 (en) * 2005-10-07 2007-04-19 Alza Corporation Osmotic dosage form with controlled release and fast release aspects
US8273075B2 (en) * 2005-12-13 2012-09-25 The Invention Science Fund I, Llc Osmotic pump with remotely controlled osmotic flow rate
US8936590B2 (en) 2005-11-09 2015-01-20 The Invention Science Fund I, Llc Acoustically controlled reaction device
US8992511B2 (en) 2005-11-09 2015-03-31 The Invention Science Fund I, Llc Acoustically controlled substance delivery device
US8083710B2 (en) 2006-03-09 2011-12-27 The Invention Science Fund I, Llc Acoustically controlled substance delivery device
US8273071B2 (en) 2006-01-18 2012-09-25 The Invention Science Fund I, Llc Remote controller for substance delivery system
US9254256B2 (en) * 2005-11-09 2016-02-09 The Invention Science Fund I, Llc Remote controlled in vivo reaction method
US9067047B2 (en) 2005-11-09 2015-06-30 The Invention Science Fund I, Llc Injectable controlled release fluid delivery system
US7942867B2 (en) 2005-11-09 2011-05-17 The Invention Science Fund I, Llc Remotely controlled substance delivery device
US20080140057A1 (en) 2006-03-09 2008-06-12 Searete Llc, A Limited Liability Corporation Of State Of The Delaware Injectable controlled release fluid delivery system
US8337777B2 (en) * 2006-06-28 2012-12-25 Applied Biosystems, Llc Sample distribution devices and methods
NZ552290A (en) * 2006-12-21 2009-05-31 Bomac Research Ltd Tablet fomulation
US9101707B2 (en) 2012-04-27 2015-08-11 Gregory Zeltser Implantable bioartificial perfusion system
SI4037666T1 (sl) 2020-12-08 2024-09-30 Ruminant Biotech Corp Limited Izboljšave naprav in postopkov za dostavo snovi živalim

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GB372040A (en) * 1931-03-21 1932-05-05 Bernard Thomson Improvements relating to control mechanism particularly with reference to gear boxes
NL175029C (nl) * 1970-12-23 1984-09-17 Boehringer Sohn Ingelheim Depotdragee, die bekleed is met een onoplosbare en onverteerbare schaal, die op een of meer plaatsen een uitsparing vertoont.
US3995632A (en) * 1973-05-04 1976-12-07 Alza Corporation Osmotic dispenser
US4381780A (en) * 1981-01-19 1983-05-03 Research Corporation Sustained release delivery system
US4449983A (en) * 1982-03-22 1984-05-22 Alza Corporation Simultaneous delivery of two drugs from unit delivery device
US4576604A (en) * 1983-03-04 1986-03-18 Alza Corporation Osmotic system with instant drug availability
US4564363A (en) * 1983-07-13 1986-01-14 Smithkline Beckman Corporation Delayed action assembly
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US4772474A (en) * 1985-08-09 1988-09-20 Alza Corporation Dispenser with internal arrangement of lamina means for dispensing beneficial agent
US4612186A (en) * 1984-03-19 1986-09-16 Alza Corporation Method for establishing blood levels of biocide in animals
US4729793A (en) * 1985-08-09 1988-03-08 Alza Corporation Composition for manufacturing wall of dispensing device
GB8417202D0 (en) * 1984-07-05 1984-08-08 Norbrook Lab Ltd Drug intermittent release device
US4608048A (en) * 1984-12-06 1986-08-26 Alza Corporation Dispensing device with drug delivery patterns
US4704118A (en) * 1985-08-16 1987-11-03 Alza Corporation Ruminant dispensing device with thermo-activated memory
US4643731A (en) * 1985-08-16 1987-02-17 Alza Corporation Means for providing instant agent from agent dispensing system
IT1188212B (it) * 1985-12-20 1988-01-07 Paolo Colombo Sistema per il rilascio a velocita' controllata di sostanze attive
US4662880A (en) * 1986-03-14 1987-05-05 Alza Corporation Pseudoephedrine, brompheniramine therapy
US4716496A (en) * 1986-05-09 1987-12-29 Eaton Corporation Panel-mounted control station housing
US4842867A (en) * 1986-05-09 1989-06-27 Alza Corporation Pulsed drug delivery of doxylamine
US4915952A (en) * 1987-02-27 1990-04-10 Alza Corporation Composition comprising drug, HPC, HPMC and PEO
US4810502A (en) * 1987-02-27 1989-03-07 Alza Corporation Pseudoephedrine brompheniramine therapy
US4915953A (en) * 1987-09-03 1990-04-10 Alza Corporation Dosage form for delivering acetaminophen or phenylpropanolamine
US4814181A (en) * 1987-09-03 1989-03-21 Alza Corporation Dosage form comprising fast agent delivery followed by slow agent delivery
US4915954A (en) * 1987-09-03 1990-04-10 Alza Corporation Dosage form for delivering a drug at two different rates
US4872873A (en) * 1987-12-14 1989-10-10 Merck & Co., Inc. Controlled release bolus device
CA1330886C (en) * 1988-01-22 1994-07-26 Bend Research Inc. Osmotic system for delivery of dilute solutions
US5045082A (en) * 1990-01-10 1991-09-03 Alza Corporation Long-term delivery device including loading dose

Also Published As

Publication number Publication date
PT96337B (pt) 1998-07-31
DE69011131T2 (de) 1994-12-01
DK0510062T3 (da) 1994-11-28
NO922656L (no) 1992-07-06
IE62391B1 (en) 1995-01-25
ZA9010342B (en) 1991-10-30
KR920703026A (ko) 1992-12-17
EP0510062B1 (en) 1994-07-27
JPH05503100A (ja) 1993-05-27
IE904657A1 (en) 1991-07-17
KR0158704B1 (ko) 1998-12-01
FI923142A0 (fi) 1992-07-08
EP0510062A1 (en) 1992-10-28
NO303862B1 (no) 1998-09-14
WO1991010423A1 (en) 1991-07-25
US5840074A (en) 1998-11-24
NO922656D0 (no) 1992-07-06
CA2032923C (en) 2000-04-11
FI923142A (fi) 1992-07-08
NZ236627A (en) 1992-05-26
AU642704B2 (en) 1993-10-28
JP3301612B2 (ja) 2002-07-15
US5045082A (en) 1991-09-03
FI105011B (fi) 2000-05-31
CA2032923A1 (en) 1991-07-11
PT96337A (pt) 1991-09-30
AU7156991A (en) 1991-08-05
DE69011131D1 (de) 1994-09-01
MX169706B (es) 1993-07-19
ATE108998T1 (de) 1994-08-15

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