MX169706B - Dispositivo de administracion prolongada que incluye dosis de carga - Google Patents

Dispositivo de administracion prolongada que incluye dosis de carga

Info

Publication number
MX169706B
MX169706B MX023897A MX2389790A MX169706B MX 169706 B MX169706 B MX 169706B MX 023897 A MX023897 A MX 023897A MX 2389790 A MX2389790 A MX 2389790A MX 169706 B MX169706 B MX 169706B
Authority
MX
Mexico
Prior art keywords
agent
delivery
term
lumen
long
Prior art date
Application number
MX023897A
Other languages
English (en)
Inventor
Anthony L Kuczynski
Atul Devdatt Ayer
James B Eckenhoff
Jeremy C Wright
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of MX169706B publication Critical patent/MX169706B/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0068Rumen, e.g. rumen bolus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61DVETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D7/00Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Medicinal Preparation (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
  • Filling Or Emptying Of Bunkers, Hoppers, And Tanks (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Testing Of Optical Devices Or Fibers (AREA)
  • Bidet-Like Cleaning Device And Other Flush Toilet Accessories (AREA)
  • Length Measuring Devices By Optical Means (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Glanulating (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Basic Packing Technique (AREA)
  • De-Stacking Of Articles (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invención se refiere a un dispositivo de administración para administrar un agente benéfico a un ambiente de uso a una velocidad sustancialmente constante durante un periodo extendido, dicho dispositivo de administración estando caracterizado porque comprende: a) primeros medios de administración de agente para colocar una primera formulación de agente benéfico en disponibilidad para el ambiente de uso, dichos primeros medios de administración de agente comprendiendo; (1) una primera formulación de agente benéfico que comprende por lo menos a dicho agente benéfico y que libera dicho agente benéfico a lo largo del tiempo dentro del ambiente de uso; y (2) medios de retención para retener la primera formulación de agente benéfico en contacto con segundos medios de administración de agente mientras que se expone la primera formulación de agente benéfico y los segundos medios de administración de agente al ambiente de uso; y (b) segundos medios de administración de agente para la administración continua y prolongada de una segunda formulación de agente benéfico al ambiente de uso, dichos segundos medios de administración de agente comprendiendo; (1) una pared de rodea y define un lúmen interno, la pared comprendiendo una composición que es permeable al paso del flúido y sustancialmente impermeable al paso de agente benéfico; (2) una segunda formulación de agente benéfico en el lúmen, que provee una formulación administrable que incluye por lo menos un agente benéfico para el ambiente de uso; (3) medios de expansión en el lúmen para desplazar dicha segunda formulación de agente benéfico del interior del lúmen al ambiente de uso después de exponerse al ambiente de uso; y (4) medios de salida en el dispositivo de administración para la administración de dicha segunda formulación de agente benéfico al ambiente de uso; las velocidades de liberación del agente de dichos primeros medios de administración de agente y dichos segundos medios de administración de agente seleccionandose de manera tal que se mantenga una velocidad de administración de agente total, sustancialmente constante durante dicho período extendido.
MX023897A 1990-01-10 1990-12-21 Dispositivo de administracion prolongada que incluye dosis de carga MX169706B (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/463,109 US5045082A (en) 1990-01-10 1990-01-10 Long-term delivery device including loading dose

Publications (1)

Publication Number Publication Date
MX169706B true MX169706B (es) 1993-07-19

Family

ID=23838902

Family Applications (1)

Application Number Title Priority Date Filing Date
MX023897A MX169706B (es) 1990-01-10 1990-12-21 Dispositivo de administracion prolongada que incluye dosis de carga

Country Status (18)

Country Link
US (2) US5045082A (es)
EP (1) EP0510062B1 (es)
JP (1) JP3301612B2 (es)
KR (1) KR0158704B1 (es)
AT (1) ATE108998T1 (es)
AU (1) AU642704B2 (es)
CA (1) CA2032923C (es)
DE (1) DE69011131T2 (es)
DK (1) DK0510062T3 (es)
ES (1) ES2056636T3 (es)
FI (1) FI105011B (es)
IE (1) IE62391B1 (es)
MX (1) MX169706B (es)
NO (1) NO303862B1 (es)
NZ (1) NZ236627A (es)
PT (1) PT96337B (es)
WO (1) WO1991010423A1 (es)
ZA (1) ZA9010342B (es)

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US5045082A (en) * 1990-01-10 1991-09-03 Alza Corporation Long-term delivery device including loading dose
US5229133A (en) * 1990-01-24 1993-07-20 Alza Corporation Delivery system comprising means for controlling internal pressure
US5474785A (en) * 1990-01-24 1995-12-12 Alza Corporation Delivery system comprising means for controlling internal pressure
US5223266A (en) * 1990-01-24 1993-06-29 Alza Corporation Long-term delivery device with early startup
US5213809A (en) * 1990-01-24 1993-05-25 Alza Corporation Delivery system comprising means for controlling internal pressure
DK0597834T3 (da) * 1990-01-24 1996-02-26 Alza Corp Afgivelsessystem
US5861166A (en) * 1991-03-12 1999-01-19 Alza Corporation Delivery device providing beneficial agent stability
US5201728A (en) * 1991-05-03 1993-04-13 Giampapa Vincent C Subcutaneous implantable multiple-agent delivery system
US5227167A (en) * 1991-06-11 1993-07-13 Alza Corporation Long-term delivery device including hydrophobic loading dose
US5240713A (en) * 1991-09-27 1993-08-31 Alza Corporation Dual rate agent delivery device
US5288214A (en) * 1991-09-30 1994-02-22 Toshio Fukuda Micropump
US5462741A (en) * 1992-08-06 1995-10-31 Alza Corporation High agent loaded controlled release dispenser
US5431919A (en) * 1993-06-23 1995-07-11 Alza Ruminal drug delivery device
US5639477A (en) * 1993-06-23 1997-06-17 Alza Corporation Ruminal drug delivery device
GB9318641D0 (en) * 1993-09-08 1993-10-27 Edko Trading Representation Compositions
NZ250188A (en) * 1993-11-11 1996-06-25 Ashmont Holdings Ltd Substitut Anthelmintic drench comprising an avermectin or milbemycin and an organic selenium salt
ZA948426B (en) * 1993-12-22 1995-06-30 Qualcomm Inc Distributed voice recognition system
US5672357A (en) * 1994-07-01 1997-09-30 Monsanto Company Method and device for implantation of large diameter objects in bovines
US5595752A (en) * 1994-07-01 1997-01-21 Monsanto Company Increasing dressing percentage and carcass weight in finishing beef cattle
US5433711A (en) * 1994-08-01 1995-07-18 Monsanto Company Syringe with cannula-protecting sheath and sealing center rod
US5690952A (en) * 1995-06-07 1997-11-25 Judy A. Magruder et al. Implantable system for delivery of fluid-sensitive agents to animals
FR2754711B1 (fr) * 1996-10-21 1999-01-29 Vandamme Thierry Dispositif de liberation avec effet retard d'une substance active, notamment veterinaire
GB2345010B (en) 1998-12-17 2002-12-31 Electrosols Ltd A delivery device
US6669954B2 (en) 2000-01-25 2003-12-30 John R. Crison Controlled release of drugs
GB0115355D0 (en) * 2001-06-22 2001-08-15 Pirrie Alastair Vaporization system
US20060020253A1 (en) * 2004-07-26 2006-01-26 Prescott Anthony D Implantable device having reservoir with controlled release of medication and method of manufacturing the same
WO2007044234A1 (en) * 2005-10-07 2007-04-19 Alza Corporation Osmotic dosage form with controlled release and fast release aspects
US8273075B2 (en) * 2005-12-13 2012-09-25 The Invention Science Fund I, Llc Osmotic pump with remotely controlled osmotic flow rate
US8936590B2 (en) 2005-11-09 2015-01-20 The Invention Science Fund I, Llc Acoustically controlled reaction device
US8992511B2 (en) 2005-11-09 2015-03-31 The Invention Science Fund I, Llc Acoustically controlled substance delivery device
US8083710B2 (en) 2006-03-09 2011-12-27 The Invention Science Fund I, Llc Acoustically controlled substance delivery device
US8273071B2 (en) 2006-01-18 2012-09-25 The Invention Science Fund I, Llc Remote controller for substance delivery system
US9254256B2 (en) * 2005-11-09 2016-02-09 The Invention Science Fund I, Llc Remote controlled in vivo reaction method
US9067047B2 (en) 2005-11-09 2015-06-30 The Invention Science Fund I, Llc Injectable controlled release fluid delivery system
US7942867B2 (en) 2005-11-09 2011-05-17 The Invention Science Fund I, Llc Remotely controlled substance delivery device
US20080140057A1 (en) 2006-03-09 2008-06-12 Searete Llc, A Limited Liability Corporation Of State Of The Delaware Injectable controlled release fluid delivery system
US8337777B2 (en) * 2006-06-28 2012-12-25 Applied Biosystems, Llc Sample distribution devices and methods
NZ552290A (en) * 2006-12-21 2009-05-31 Bomac Research Ltd Tablet fomulation
US9101707B2 (en) 2012-04-27 2015-08-11 Gregory Zeltser Implantable bioartificial perfusion system
SI4037666T1 (sl) 2020-12-08 2024-09-30 Ruminant Biotech Corp Limited Izboljšave naprav in postopkov za dostavo snovi živalim

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Also Published As

Publication number Publication date
PT96337B (pt) 1998-07-31
DE69011131T2 (de) 1994-12-01
DK0510062T3 (da) 1994-11-28
NO922656L (no) 1992-07-06
IE62391B1 (en) 1995-01-25
ZA9010342B (en) 1991-10-30
KR920703026A (ko) 1992-12-17
EP0510062B1 (en) 1994-07-27
JPH05503100A (ja) 1993-05-27
IE904657A1 (en) 1991-07-17
KR0158704B1 (ko) 1998-12-01
FI923142A0 (fi) 1992-07-08
EP0510062A1 (en) 1992-10-28
NO303862B1 (no) 1998-09-14
WO1991010423A1 (en) 1991-07-25
US5840074A (en) 1998-11-24
NO922656D0 (no) 1992-07-06
CA2032923C (en) 2000-04-11
FI923142A (fi) 1992-07-08
NZ236627A (en) 1992-05-26
AU642704B2 (en) 1993-10-28
JP3301612B2 (ja) 2002-07-15
US5045082A (en) 1991-09-03
ES2056636T3 (es) 1994-10-01
FI105011B (fi) 2000-05-31
CA2032923A1 (en) 1991-07-11
PT96337A (pt) 1991-09-30
AU7156991A (en) 1991-08-05
DE69011131D1 (de) 1994-09-01
ATE108998T1 (de) 1994-08-15

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