ES2089122T3 - Vectores de expresion de adn recombinante y compuestos de adn que codifican la actividad de la isopenicilina n epimerasa. - Google Patents

Vectores de expresion de adn recombinante y compuestos de adn que codifican la actividad de la isopenicilina n epimerasa.

Info

Publication number
ES2089122T3
ES2089122T3 ES91300540T ES91300540T ES2089122T3 ES 2089122 T3 ES2089122 T3 ES 2089122T3 ES 91300540 T ES91300540 T ES 91300540T ES 91300540 T ES91300540 T ES 91300540T ES 2089122 T3 ES2089122 T3 ES 2089122T3
Authority
ES
Spain
Prior art keywords
isopenicillin
expression vectors
epimerase activity
compounds
coding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91300540T
Other languages
English (en)
Inventor
Barbara Jean Weigel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of ES2089122T3 publication Critical patent/ES2089122T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

LA INVENCION ACTUAL PROPORCIONA COMPUESTOS DE DNA QUE CODIFICAN LA ACTIVIDAD DE LA ISOPENICILINA N EPIMERASA. LOS COMPUESTOS PUEDEN UTILIZARSE PARA CONSTRUIR VECTORES DE EXPRESION DE DNA RECOMBINADO PARA UNA AMPLIA VARIEDAD DE CELULAS HUESPED, INCLUYENDO E, COLI, PENICILINA, ESTREPTOMICINAS, ASPERGILLUS Y CEFALOSPORIUM. LA INVENCION COMPRENDE TAMBIEN METODOS PARA EXPRESAR LA ACTIVIDAD DE LA ISOPENICILINA N EPIMERASA EN CELULAS HUESPED.
ES91300540T 1990-01-26 1991-01-24 Vectores de expresion de adn recombinante y compuestos de adn que codifican la actividad de la isopenicilina n epimerasa. Expired - Lifetime ES2089122T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US47047690A 1990-01-26 1990-01-26

Publications (1)

Publication Number Publication Date
ES2089122T3 true ES2089122T3 (es) 1996-10-01

Family

ID=23867771

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91300540T Expired - Lifetime ES2089122T3 (es) 1990-01-26 1991-01-24 Vectores de expresion de adn recombinante y compuestos de adn que codifican la actividad de la isopenicilina n epimerasa.

Country Status (9)

Country Link
EP (1) EP0444775B1 (es)
JP (1) JPH04211381A (es)
AT (1) ATE139571T1 (es)
CA (1) CA2034735A1 (es)
DE (1) DE69120315T2 (es)
DK (1) DK0444775T3 (es)
ES (1) ES2089122T3 (es)
GR (1) GR3020786T3 (es)
IL (1) IL97000A0 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9637746B2 (en) 2008-12-15 2017-05-02 Greenlight Biosciences, Inc. Methods for control of flux in metabolic pathways
EP2566953B1 (en) 2010-05-07 2019-01-02 Greenlight Biosciences, Inc. Methods for control of flux in metabolic pathways through enzyme relocation
WO2012030980A1 (en) 2010-08-31 2012-03-08 Greenlight Biosciences, Inc. Methods for control of flux in metabolic pathways through protease manipulation
EP2753702B1 (en) 2011-09-09 2021-12-15 GreenLight Biosciences, Inc. Cell-free preparation of carbapenems
DK3030671T3 (en) 2013-08-05 2019-01-21 Greenlight Biosciences Inc MODIFIED PROTEINS WITH A PROTEASE CLEANING PLACE
KR20230048162A (ko) 2015-03-30 2023-04-10 그린라이트 바이오사이언시스, 아이엔씨. 리보핵산의 무세포 생산
AU2017246458B2 (en) 2016-04-06 2022-08-11 Greenlight Biosciences, Inc. Cell-free production of ribonucleic acid
WO2018125863A1 (en) * 2017-01-01 2018-07-05 The Regents Of The University Of California Fluorescence-based reporters for mutagenesis detection in e. coli
IL273887B (en) 2017-10-11 2022-09-01 Greenlight Biosciences Inc Methods and preparations for the production of nucleoside triphosphate and ribonucleic acid

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4536476A (en) * 1982-08-23 1985-08-20 Queen's University At Kingston Stable epimerase reagent, cyclase reagent and ring expansion reagent for cell-free production of cephalosporins
DE68920987T2 (de) * 1988-12-22 1995-06-22 Lilly Co Eli Rekombinante DNA enthaltende Expressionsvektoren und für Isopenicillin-N-Epimerase-(Racemase)-Aktivität kodierende DNS-Verbindungen.

Also Published As

Publication number Publication date
IL97000A0 (en) 1992-03-29
DE69120315D1 (de) 1996-07-25
EP0444775B1 (en) 1996-06-19
EP0444775A1 (en) 1991-09-04
JPH04211381A (ja) 1992-08-03
ATE139571T1 (de) 1996-07-15
DK0444775T3 (da) 1996-07-15
DE69120315T2 (de) 1996-11-21
GR3020786T3 (en) 1996-11-30
CA2034735A1 (en) 1991-07-27

Similar Documents

Publication Publication Date Title
NZ221119A (en) Proteins with factor viii activity produced by microorganisms produced by genetic engineering
DE68928545D1 (de) Herstellung von glukoseoxidase in rekombinanten systemen
DE68922917T2 (de) KEX2-Endoprotease und Verfahren zu ihrer Herstellung.
ES2067556T3 (es) Vectores de expresion de adn recombinante y compuestos de adn que codifican la actividad isopenicilina n epimerasa (racemasa).
AU5233686A (en) Dna sequence encoding a hirudin-like protein and process for preparing such protein
ES2043607T3 (es) Agentes fibrinoliticos modificados.
ES2089122T3 (es) Vectores de expresion de adn recombinante y compuestos de adn que codifican la actividad de la isopenicilina n epimerasa.
ES2104596T3 (es) Nuevos polipeptidos, secuencias de adn que permiten su expresion, metodo de preparacion, y utilizacion.
DK102088D0 (da) Rekombinant-dna-udtrykkelsesvektorer og dna-produkter, der koder deacetoxycephalosporin c syntetase og deacetylsephalosporin c synthetase
DK606088A (da) Rekombinant-dna-udtrykkelsesvektorer og dna-forbindelser, der koder for isopenicillin n synthetase
FR2681076B1 (fr) Adn recombinant codant pour une proteine a activite endochitinase.
ATE189479T1 (de) Expressionsvektoren zur synthese von proteinen in der spalthefe schizosaccharomyces pombe
ES2086374T3 (es) Vectores de expresion de adn recombinante y compuestos de adn que codifican la actividad aciltransferasa de aspergillus.
AU7963487A (en) Recombinant ligninase
ES2078229T3 (es) Procedimiento para la preparacion de un polipeptido similar a la motilina y su expresion.
NO883963D0 (no) Modifiserte plasminogen-aktivatorer.
IT8521507A0 (it) Vettore di clonaggio, molecole di dna ricombinante, ceppi di bacillus subtilis trasformati con dette molecole e metodi per l'espressione di geni eterologhi e produzione e secrezione di proteine codificate da detti geni.
EP0197797A3 (en) Improved recombinant hosts, their production and use
EP0165759A3 (en) Mammalian promotors useful in yeast expression

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 444775

Country of ref document: ES

FG2A Definitive protection

Ref document number: 444775

Country of ref document: ES