DE69120315D1 - Rekombinante DNA-Expressionsvektoren und DNA-Zusammensetzungen, die Isopenizillin N-Epimerase-Aktivität kodieren - Google Patents

Rekombinante DNA-Expressionsvektoren und DNA-Zusammensetzungen, die Isopenizillin N-Epimerase-Aktivität kodieren

Info

Publication number
DE69120315D1
DE69120315D1 DE69120315T DE69120315T DE69120315D1 DE 69120315 D1 DE69120315 D1 DE 69120315D1 DE 69120315 T DE69120315 T DE 69120315T DE 69120315 T DE69120315 T DE 69120315T DE 69120315 D1 DE69120315 D1 DE 69120315D1
Authority
DE
Germany
Prior art keywords
expression vectors
epimerase activity
isopenicillin
recombinant dna
dna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69120315T
Other languages
English (en)
Other versions
DE69120315T2 (de
Inventor
Barbara Jean Weigel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of DE69120315D1 publication Critical patent/DE69120315D1/de
Application granted granted Critical
Publication of DE69120315T2 publication Critical patent/DE69120315T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
DE69120315T 1990-01-26 1991-01-24 Rekombinante DNA-Expressionsvektoren und DNA-Zusammensetzungen, die Isopenizillin N-Epimerase-Aktivität kodieren Expired - Fee Related DE69120315T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US47047690A 1990-01-26 1990-01-26

Publications (2)

Publication Number Publication Date
DE69120315D1 true DE69120315D1 (de) 1996-07-25
DE69120315T2 DE69120315T2 (de) 1996-11-21

Family

ID=23867771

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69120315T Expired - Fee Related DE69120315T2 (de) 1990-01-26 1991-01-24 Rekombinante DNA-Expressionsvektoren und DNA-Zusammensetzungen, die Isopenizillin N-Epimerase-Aktivität kodieren

Country Status (9)

Country Link
EP (1) EP0444775B1 (de)
JP (1) JPH04211381A (de)
AT (1) ATE139571T1 (de)
CA (1) CA2034735A1 (de)
DE (1) DE69120315T2 (de)
DK (1) DK0444775T3 (de)
ES (1) ES2089122T3 (de)
GR (1) GR3020786T3 (de)
IL (1) IL97000A0 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9637746B2 (en) 2008-12-15 2017-05-02 Greenlight Biosciences, Inc. Methods for control of flux in metabolic pathways
EP2566953B1 (de) 2010-05-07 2019-01-02 Greenlight Biosciences, Inc. Verfahren zur flusssteuerung bei stoffwechselwegen druch enzymumpositionierung
WO2012030980A1 (en) 2010-08-31 2012-03-08 Greenlight Biosciences, Inc. Methods for control of flux in metabolic pathways through protease manipulation
EP2753702B1 (de) 2011-09-09 2021-12-15 GreenLight Biosciences, Inc. Zellfreie herstellung von carbapenemen
DK3030671T3 (en) 2013-08-05 2019-01-21 Greenlight Biosciences Inc MODIFIED PROTEINS WITH A PROTEASE CLEANING PLACE
KR20230048162A (ko) 2015-03-30 2023-04-10 그린라이트 바이오사이언시스, 아이엔씨. 리보핵산의 무세포 생산
AU2017246458B2 (en) 2016-04-06 2022-08-11 Greenlight Biosciences, Inc. Cell-free production of ribonucleic acid
WO2018125863A1 (en) * 2017-01-01 2018-07-05 The Regents Of The University Of California Fluorescence-based reporters for mutagenesis detection in e. coli
IL273887B (en) 2017-10-11 2022-09-01 Greenlight Biosciences Inc Methods and preparations for the production of nucleoside triphosphate and ribonucleic acid

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4536476A (en) * 1982-08-23 1985-08-20 Queen's University At Kingston Stable epimerase reagent, cyclase reagent and ring expansion reagent for cell-free production of cephalosporins
DE68920987T2 (de) * 1988-12-22 1995-06-22 Lilly Co Eli Rekombinante DNA enthaltende Expressionsvektoren und für Isopenicillin-N-Epimerase-(Racemase)-Aktivität kodierende DNS-Verbindungen.

Also Published As

Publication number Publication date
IL97000A0 (en) 1992-03-29
ES2089122T3 (es) 1996-10-01
EP0444775B1 (de) 1996-06-19
EP0444775A1 (de) 1991-09-04
JPH04211381A (ja) 1992-08-03
ATE139571T1 (de) 1996-07-15
DK0444775T3 (da) 1996-07-15
DE69120315T2 (de) 1996-11-21
GR3020786T3 (en) 1996-11-30
CA2034735A1 (en) 1991-07-27

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Legal Events

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8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee