ES2088523T3 - Procedimiento de preparacion de capsulas de gelatina dura que contienen extractos de hierbas chinas. - Google Patents

Procedimiento de preparacion de capsulas de gelatina dura que contienen extractos de hierbas chinas.

Info

Publication number
ES2088523T3
ES2088523T3 ES92115192T ES92115192T ES2088523T3 ES 2088523 T3 ES2088523 T3 ES 2088523T3 ES 92115192 T ES92115192 T ES 92115192T ES 92115192 T ES92115192 T ES 92115192T ES 2088523 T3 ES2088523 T3 ES 2088523T3
Authority
ES
Spain
Prior art keywords
kampo medicine
hard capsules
kampo
medicine
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92115192T
Other languages
English (en)
Inventor
Toshihiro Uchida
Shin Ichiro Konishi
Takayoshi Kimura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tsumura and Co
Original Assignee
Tsumura and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tsumura and Co filed Critical Tsumura and Co
Application granted granted Critical
Publication of ES2088523T3 publication Critical patent/ES2088523T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539—Scutellaria (skullcap)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718—Coptis (goldthread)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725—Ziziphus, e.g. jujube
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/74—Rubiaceae (Madder family)
    • A61K36/744—Gardenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/756—Phellodendron, e.g. corktree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

CUANDO UN EXTRACTO EN POLVO DE MEDICINA KAMPO SE ENCAPSULA EN CAPSULAS DURAS, LOS EFECTOS FARMACEUTICOS DE LA MEDICINA KAMPO NO PUEDEN ALCANZARSE PLENAMENTE, YA QUE LA DISOLUCION DEL CONTENIDO DE LAS CAPSULAS DURAS REQUIERE UN LARGO PERIODO DE TIEMPO. POR LO TANTO, EL PRESENTE INVENTO PRETENDE OFRECER CAPSULAS DURAS DE MEDICINA KAMPO CON BUENAS PROPIEDADES DE DISOLUCION. ESTE INVENTO OFRECE UN PROCESO PARA PRODUCIR CAPSULAS DURAS DE MEDICINA KAMPO QUE COMPRENDE COMPRIMIR EXTRACTO EN POLVO DE MEDICINA KAMPO, MEZCLAR ESTEARATO DE MAGNESIO CON EL EXTRACTO EN POLVO DE MEDICINA KAMPO COMPRIMIDO Y RELLENAR CON LA MEZCLA CAPSULAS DURAS DE GELATINA. ES PREFERIBLE QUE LA RELACION PESO DE ESTEARATO DE MAGNESIO CON EL EXTRACTO EN POLVO DE MEDICINA KAMPO ESTE ENTRE 0,5/100 Y 3/100. ADEMAS, ES PREFERIBLE QUE DICHA MEDICINA KAMPO SE SELECCIONE DE OREN-GEDOKU-TO, SHO-SAIKO-TO, NINJIN-TO, SAN''OSHASHIN-TO, MAO-BUSHI-SAISHIN-TO, ANCHU-SAN, KEISHI-BUKURYOGAN, BYAKKO-KA-NINJIN-TO, SHAKUYAKU-KANZO-TO Y SAREI-TO.
ES92115192T 1991-09-05 1992-09-04 Procedimiento de preparacion de capsulas de gelatina dura que contienen extractos de hierbas chinas. Expired - Lifetime ES2088523T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP25274791 1991-09-05

Publications (1)

Publication Number Publication Date
ES2088523T3 true ES2088523T3 (es) 1996-08-16

Family

ID=17241721

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92115192T Expired - Lifetime ES2088523T3 (es) 1991-09-05 1992-09-04 Procedimiento de preparacion de capsulas de gelatina dura que contienen extractos de hierbas chinas.

Country Status (5)

Country Link
US (1) US5318798A (es)
EP (1) EP0530833B1 (es)
AT (1) ATE136785T1 (es)
DE (1) DE69209942T2 (es)
ES (1) ES2088523T3 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0818195B1 (en) * 1995-03-29 2003-11-26 Shionogi & Co., Ltd. Gelatin capsule with adjusted water activity
KR100195886B1 (ko) * 1996-11-01 1999-06-15 김상조 당뇨병 치료용 의약조성물
DE19758100B4 (de) 1997-12-18 2006-05-04 Lichtwer Pharma Ag Verfahren zum Herstellen von Pflanzenextrakt enthaltenden pharmazeutischen Formulierungen
AR020343A1 (es) * 1998-11-24 2002-05-08 Steigerwald Arzlneimittelwerk Metodo para producir farmacos que contienen extractos de plantas en una forma solida de aplicacion.
US20010024664A1 (en) * 1999-03-19 2001-09-27 Obukowicz Mark G. Selective COX-2 inhibition from edible plant extracts
US6238696B1 (en) 2000-01-07 2001-05-29 Gaia Herbs, Inc. Process for providing herbal medicants in cellulose derivative capsules
DE10112167C2 (de) * 2001-03-12 2003-02-13 Bionorica Ag Verfahren zur schonenden Gewinnung von Trockenextrakten
DE10144108A1 (de) 2001-09-03 2003-04-30 Steigerwald Arzneimittelwerk Verfahren zur Herstellung von Tabletten aus pflanzlichen Extrakten
US20040062823A1 (en) * 2001-12-13 2004-04-01 Obukowicz Mark G. Selective cox-2 inhibition from non-edible plant extracts
US20040126438A1 (en) * 2001-12-13 2004-07-01 Obukowicz Mark G. Selective cox-2 inhibition from plant extracts
TWI275397B (en) * 2001-12-21 2007-03-11 Sun Ten Pharmaceutical Co Ltd Herbal composition, use thereof in protection of endothelial cell and in anti-inflammation, and preparation method thereof
US7258877B2 (en) * 2001-12-21 2007-08-21 Sunten Phytotech Co., Ltd. Herbal pharmaceutical composition for treatment of cardiovascular disease
ES2349268T3 (es) * 2002-07-12 2010-12-29 TSUMURA & CO. Composición de comprimido que contiene un extracto de la medicina ortodoxa china y procedimiento para su producción.
US7051606B2 (en) * 2004-01-30 2006-05-30 Andrx Labs Llc Dosage form holder device and methods for immersion testing
US20090098228A1 (en) * 2007-10-10 2009-04-16 Tsumura & Co. Agent and method for improvement of impairment of learning and memory
CN102600273A (zh) * 2011-08-25 2012-07-25 浙江省中药研究所有限公司 一种新鲜栀子的加工方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2130113C3 (de) * 1970-06-22 1980-07-03 Scherico Ltd., Luzern (Schweiz) Gentamicin B, Gentamicin B1 und Gentamicin X, Verfahren zu deren Gewinnung und diese Gentamicine enthaltende pharmazeutische Zubereitungen
US3909444A (en) * 1971-08-05 1975-09-30 Ncr Co Microcapsule
US3780065A (en) * 1972-08-10 1973-12-18 Smithkline Corp Phenylvulpinic acid derivatives
JPS5115094B2 (es) * 1972-11-01 1976-05-14
GB8413191D0 (en) * 1984-05-23 1984-06-27 Beecham Group Plc Pharmaceutical composition
JPS61205272A (ja) * 1985-03-08 1986-09-11 Tsumura Juntendo Inc 新規なタンニン
KR920003577B1 (ko) * 1987-12-10 1992-05-04 주식회사 쓰무라 항 레트로바이러스제
JP3179522B2 (ja) * 1991-06-26 2001-06-25 宏樹 宮松 染色繊維製品およびその製造法

Also Published As

Publication number Publication date
EP0530833B1 (en) 1996-04-17
DE69209942T2 (de) 1996-09-05
US5318798A (en) 1994-06-07
ATE136785T1 (de) 1996-05-15
DE69209942D1 (de) 1996-05-23
EP0530833A1 (en) 1993-03-10

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